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Episode 17 - Enough about DAT | Approach to DAT Negative Haemolysis
Manage episode 440506558 series 3596833
MAHA TMA Gandhi once said a cell for a cell makes the whole body anaemic, or something along those lines. There’s so much more to DAT negative haemolysis than just DIC. Get out those buckets and put your sorting hats on - it’s time to go where detective Coombs never dared to and look over the DAT negative haemolytic processes.
Timestamps
2:42 - Approach to DAT negatives - main categories
4:53 - Intrinsic Bucket 1: Membrane disorders
16:16 - Intrinsic Bucket 2: Enzyme disorders
18:51 - Intrinsic Bucket 3: Haemoglobin disorders
24:05 - Extrinsic Bucket 1: Microangiopathies
26:54 - Extrinsic Bucket 2: Infections
28:07 - Extrinsic Bucket 3: "Macroangiopathies"
30:58 - Extrinsic Bucket 4: Liver stuff
34:07 - Take home messages
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Chapters
1. Episode 17 - Enough about DAT | Approach to DAT Negative Haemolysis (00:00:00)
2. Approach to DAT negatives - main categories (00:02:42)
3. Intrinsic Bucket 1: Membrane disorders (00:04:53)
4. Intrinsic Bucket 2: Enzyme disorders (00:16:16)
5. Intrinsic Bucket 3: Haemoglobin disorders (00:18:51)
6. Extrinsic Bucket 1: Microangiopathies (00:24:05)
7. Extrinsic Bucket 2: Infections (00:26:54)
8. Extrinsic Bucket 3: "Macroangiopathies" (00:28:07)
9. Extrinsic Bucket 4: Liver stuff (00:30:58)
10. Take home messages (00:34:07)
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