#56 The $101M Global Race to Redefine Aging: Jamie Justice on the Science of Longevity, and Why Aging Is an Opportunity, Not a Decline

Ageless Athlete - Longevity Insights From Adventure Sports Legends

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What if aging didn’t have to mean decline? What if the years ahead could be just as vibrant as your youth—if not more so? In this week’s episode of Ageless Athlete, Jamie Justice, Executive Vice President of Health at XPRIZE, reveals how she’s leading a $101 million global competition to make that vision a reality.

This episode is packed with mind-expanding insights, but here’s a preview of the most compelling takeaways:

A Personal Journey That Inspires
Jamie’s story is one of resilience and adventure. From ultra-running streaks spanning nearly two years to parenting competitive climbers, Jamie lives the philosophy of "ageless." Her mother, who sold everything in her 70s to live out of a van and explore the world, embodies the possibilities of living fully at any age. Jamie’s life is a testament to the mindset she’s advocating—a perfect balance of science and the human spirit.
The Bold Vision of XPRIZE Healthspan
Forget pills and quick fixes. The XPRIZE Healthspan competition is bringing together over 550 teams from 55 countries to develop breakthrough therapies, public health interventions, and lifestyle solutions that extend healthspan. Innovations range from repurposed drugs and stem cell therapies to meditation and housing-first models for improving health.
What You Eat (and When) Matters More Than You Think
Jamie shares why diet quality trumps calorie counting and how simple changes in meal timing can dramatically impact your health. Plus, she explains how your circadian rhythm might hold the key to living longer and better.
Why Following Brian Johnson May Be the Wrong Path
Jamie dives into the challenges of “biohacking” as it’s often presented by high-profile figures like Brian Johnson. While they may market one-size-fits-all solutions, Jamie explains why aging is deeply personal, influenced by biology, environment, and individual needs. Her advice? Science-backed personalization—not cookie-cutter regimens—is the future of longevity.
The Human Side of Science
Beyond the labs and clinical trials, Jamie’s insights are grounded in a deeply human perspective. From enduring personal loss to celebrating the small joys of life, she reminds us that longevity isn’t just about living longer—it’s about living better.

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