Process Analytical Technologies: Real-Time Insight for Smarter Manufacturing

In this episode, we speak with Carrie Mason, Thad Webster, and Ryan McDougall from Lonza’s PAT Center of Excellence about how Process Analytical Technologies are transforming the way biologics are developed and produced.

This episode of A View On takes us inside the manufacturing suite, where data, sensors, and decision-making converge in real time. Our guests explain how process analytical technologies (PAT) bring advanced analytics and spectroscopy directly into bioprocesses, allowing operators and scientists to “see” what’s happening inside a bioreactor without taking samples out.

Traditionally, biomanufacturing has depended on offline sampling, where materials are removed and sent to the lab for quality testing, a process that can take hours or even days. With PAT, those same insights can now be gathered in real time, enabling faster responses, greater reproducibility, and reduced batch variability.

Together, these approaches are changing not just how data are collected, but how manufacturing decisions are made, turning process analytics into a central pillar of modern bioproduction.