In this episode of Gradient Dissent, Lukas Biewald talks with Martin Shkreli — the infamous "pharma bro" turned founder — about his path from hedge fund manager and pharma CEO to convicted felon and now software entrepreneur. Shkreli shares his side of the drug pricing controversy, reflects on his prison experience, and explains how he rebuilt his …

In this episode of Gradient Dissent, host Lukas Biewald talks with Sualeh Asif, the CPO and co-founder of Cursor, one of the fastest-growing and most loved AI-powered coding platforms. Sualeh shares the story behind Cursor’s creation, the technical and design decisions that set it apart, and how AI models are changing the way we build software. The…

In this episode of Gradient Dissent, host Lukas Biewald talks with Christopher Ahlberg, CEO of Recorded Future, a pioneering cybersecurity company leveraging AI to provide intelligence insights. Christopher shares his fascinating journey from founding data visualization startup Spotfire to building Recorded Future into an industry leader, eventuall…

In this episode of Gradient Dissent, host Lukas Biewald speaks with Captain Jon Haase, United States Navy about real-world applications of AI and autonomy in defense. From underwater mine detection with autonomous vehicles to the ethics of lethal AI systems, this conversation dives into how the U.S. military is integrating AI into mission-critical …

In this episode of Gradient Dissent, host Lukas Biewald sits down with João Moura, CEO & Founder of CrewAI, one of the leading platforms enabling AI agents for enterprise applications. Joe shares insights into how AI agents are being successfully deployed in over 40% of Fortune 500 companies, what tools these agents rely on, and how software compan…

In this episode of Gradient Dissent, host Lukas Biewald sits down with Mike Knoop, Co-founder and CEO of Ndea, a cutting-edge AI research lab. Mike shares his journey from building Zapier into a major automation platform to diving into the frontiers of AI research. They discuss DeepSeek’s R1, OpenAI’s O-series models, and the ARC Prize, a competiti…

In this episode of Gradient Dissent, host Lukas Biewald sits down with David Cahn, partner at Sequoia Capital, for a compelling discussion on the dynamic world of AI investments. They dive into recent developments, including DeepSeek and Stargate, exploring their implications for the AI industry. Drawing from his articles, "AI's $200 Billion Questi…

In this episode of Gradient Dissent, Akshay Agrawal, Co-Founder of Marimo, joins host Lukas Biewald to discuss the future of collaborative AI development. They dive into how Marimo is enabling developers and researchers to collaborate seamlessly on AI projects, the challenges of scaling AI tools, and the importance of fostering open ecosystems for …

In this episode of Gradient Dissent, Joseph E. Gonzalez, EECS Professor at UC Berkeley and Co-Founder at RunLLM, joins host Lukas Biewald to explore innovative approaches to evaluating LLMs. They discuss the concept of vibes-based evaluation, which examines not just accuracy but also the style and tone of model responses, and how Chatbot Arena has …

In this episode of Gradient Dissent, Julian Green, Co-founder & CEO of Brightband, joins host Lukas Biewald to discuss how AI is transforming weather forecasting and climate solutions. They explore Brightband's innovative approach to using AI for extreme weather prediction, the shift from physics-based models to AI-driven forecasting, and the poten…

In this episode of Gradient Dissent, Jonathan Siddharth, CEO & Co-Founder of Turing, joins host Lukas Biewald to discuss the path to AGI. They explore how Turing built a "developer cloud" of 3.7 million engineers to power AGI training, providing high-quality code and reasoning data to leading AI labs. Jonathan shares insights on Turing’s journey, f…

In this episode of Gradient Dissent, Guillermo Rauch, CEO & Founder of Vercel, joins host Lukas Biewald for a wide ranging discussion on how AI is changing web development and front end engineering. They discuss how Vercel’s v0 expert AI agent is generating code and UI based on simple ChatGPT-like prompts, the importance of releasing daily for AI a…

In this episode of Gradient Dissent, Snowflake CEO Sridhar Ramaswamy joins host Lukas Biewald to explore how AI is transforming enterprise data strategies. They discuss Sridhar's journey from Google to Snowflake, diving into the evolving role of foundation models, Snowflake’s AI strategy, and the challenges of scaling AI in business. Sridhar also s…

In this episode of Gradient Dissent, Erik Bernhardsson, CEO & Founder of Modal Labs, joins host Lukas Biewald to discuss the future of machine learning infrastructure. They explore how Modal is enhancing the developer experience, handling large-scale GPU workloads, and simplifying cloud execution for data teams. If you’re into AI, data pipelines, o…

In this episode of Gradient Dissent, Howie Lou, CEO of Airtable, joins host Lukas Biewald to dive into Airtable's transformation from a no-code app builder to a platform capable of supporting complex AI-driven workflows. They discuss the strategic decisions that propelled Airtable's growth, the challenges of scaling AI in enterprise settings, and t…

In this episode of Gradient Dissent, Andrew Feldman, CEO of Cerebras Systems, joins host Lukas Biewald to discuss the latest advancements in AI inference technology. They explore Cerebras Systems' groundbreaking new AI inference product, examining how their wafer-scale chips are setting new benchmarks in speed, accuracy, and cost efficiency. Andrew…

In this episode of Gradient Dissent, Kanjun Qiu, CEO and Co-founder of Imbue, joins host Lukas Biewald to discuss how AI agents are transforming code generation and software development. Discover the potential impact and challenges of creating autonomous AI systems that can write and verify code and and learn about the practical research involved. …