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Welcome to The Lean AI Podcast, where we want to flip the AI conversation on its head by offering invaluable insights into the practical application of AI, the challenges companies face, and the strategies used to achieve success. In each episode we speak with guests who challenge established views and offer disruptive perspectives, providing new, actionable ideas for companies looking to effectively implement AI by applying Lean Startup methodologies.
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Tools for Scale

Causeartist

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Grant Trahant interviews early stage founders and product creators for insight on features and strategies they use to scale. Topics include no-code, sass, bootstrapping, content creation, solo entrepreneurship, freelancing, and tons more.
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Inside Outside

Brian Ardinger, Founder of NXXT, Inside Outside Innovation podcast, InsideOutside.io, and the Inside Outside Innovation Summit

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Inside Outside Innovation explores the ins and outs of innovation with raw stories, real insights, and tactical advice from the best and brightest in startups & corporate innovation. Each week we bring you the latest thinking on talent, technology, and the future of innovation. Join our community of movers, shakers, makers, founders, builders, and creators to help speed up your knowledge, skills, and network. Previous guests include thought leaders such as Brad Feld, Arlan Hamilton, Jason Ca ...
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Founder, entrepreneur, and best-selling author of The Lean Startup Eric Ries discusses how to build profitable companies for the long-term benefit of society. Ries talks with world-class technologists, thought leaders, executives, and others working to create a new ecosystem of trustworthy organizations with limitless potential for growth and a deep commitment to purpose. Together, they uncover the tools and methods to ensure the next generation of companies are designed to maximize human fl ...
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Starting it Up is where dozens of the top startup founders, CEOs, and investors share their entrepreneurial stories. Hosted by Ben Burman, each episode uncovers actionable information that you can learn from and use on your own journey.
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Innovation Rockstars

Dr. Christian Mühlroth, ITONICS

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The Innovation Rockstars podcast is your no-nonsense guide to all things corporate innovation. With a focus on actionable insights and real-world experiences, we dive deep into the practices that drive sustainable growth and transformative change. From corporate foresight to ideation and creativity to hands-on execution, our episodes bring you unfiltered conversations with the minds shaping the future of business. Tune in!
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Future Squared, hosted by Steve Glaveski, brings you conversations with icons from across different fields to help you make better decisions, kick goals in your professional and personal life and better navigate a fast-changing and uncertain world. Learn from luminaries like Tyler Cowen, Jason Calacanis, Brad Feld, Seth Godin, Gretchen Rubin, Annie Duke, Kevin Kelly, Scott Belsky, Neil Patel, Adam Grant, Nir Eyal, Oliver Burkeman, Brad Feld, Steve Blank, and so many others. Find out more: ht ...
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The Growth Hacking & Product Growth Podcast

Featuring Neil Patel, Ari Meisel, Casey Armstrong and many more twice a week

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The Growth Hacking Podcast is a bi-weekly show created for YOU, the Startup Founder, Marketing Expert or Investor. If you are looking for inspiration and ACTIONABLE advice on how to GROW your Startup, Laura Moreno delivers great interviews twice a week. Each episode brings you a successful Startup Founder or Growth Hacker who shares a Growth Hacking Strategy that worked for them. Each episode ends with the Lightning Round where they will share with you their secrets for lean growth and success!
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Anthony Gold from Anthony’s Desk shares his lessons learned from entrepreneurship, building social impact businesses, startup investing, running successful for-profit and nonprofit organizations, and his own personal growth. He’s had the great fortune of being an investor, entrepreneur, CEO, software developer, hardware engineer, and intern - and is still amazed that one of the supercomputers he architected is in the Guinness Book of World Records. Anthony has had his work, including his mos ...
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Building Biotechs

Recruitomics Consulting

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From the ground floor to the C-Suite, Building Biotechs offers a behind-the-scenes look into the strategy that goes into launching and scaling successful biotech and life science companies. We talk with biotech executives, founders, HR leaders, and culture builders to learn how they think about growing companies with intention, and discuss the valuable lessons they’ve learned along the way.
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In this conversation, Ben Haefle, CEO of Lean Startup Co., discusses the realities of corporate innovation, emphasizing the importance of core innovation over disruptive innovation. He explains the Lean Startup methodology, focusing on strategic alignment, milestones, team roles, governance, and culture. The discussion also touches on the concept o…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Philip Chew, a veteran technologist with experience building platforms at financial companies since the 1990s. Together, they explore Philip's unique approach to leading AI transformation in large corporations, including his portfolio management methodology, the importance of brea…
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What does it take to challenge a century-old status quo in aviation? In this episode of The Eric Ries Show, I sit down with Blake Scholl, Founder and CEO of Boom Supersonic, a company on a mission to bring back supersonic air travel—sustainably and affordably. Blake doesn’t come from aerospace. He’s a computer scientist and former Amazon engineer w…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Adam Newton, AI transformation leader with experience at EON, Danone, and Amazon. Together, they explore the critical difference between problem-focused and technology-focused AI initiatives, the importance of strategic speed over operational speed, and practical frameworks for se…
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In this episode of The Eric Ries Show, I’m joined by Maria Colacurcio, Co-Founder and CEO of Syndio, a workplace equity analytics platform. Syndio helps companies close pay gaps and build high-trust organizations. Maria has had a long career in leadership, previously co-founding Smartsheet and serving as a senior leader at Starbucks, where she focu…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Kunal Sawarkar, Chief Data Scientist and Distinguished Engineer at IBM. Together, they discuss practical strategies for embedding AI into products successfully, including Kunal's "burning star syndrome" approach to AI investment, the importance of customer-focused problem solving,…
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In this episode of The Eric Ries Show, I sit down with Ev Williams—someone whose work has profoundly shaped the modern internet. Ev co-founded Twitter, created Medium, and before all that, built Blogger, the original blogging platform (and the one where my own blog, Startup Lessons Learned, still lives today). We cover a wide range of topics, but a…
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In this episode of The Eric Ries Show, I'm joined by Jess Mah, an extraordinary entrepreneur who launched her first six-figure business in middle school and went on to co-found more than 10 companies collectively valued at over $1 billion. Jess rose to public acclaim and earned a spot on Forbes' 30 Under 30 while privately facing the reality that h…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Supreet Kaur, AI professional at Microsoft. Together, they discuss strategic approaches for securing leadership buy-in for AI initiatives, the importance of aligning AI with business problems, and how to effectively communicate AI progress to maintain momentum and support from exe…
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The truth behind the Grammy Awards 🏆 What does it really take to win? How are nominees selected, and what role does AI play in music today? Panos A. Panay, President of the Recording Academy, reveals everything - from the intense behind-the-scenes orchestration of music’s biggest night to how technology and creativity intersect. Get insider access …
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In this episode of The Eric Ries Show, I sit down with Marten Mickos, a serial tech CEO who has been at the forefront of some of the most transformative moments in open-source technology. From leading MySQL through its groundbreaking journey to guiding HackerOne as a pioneering bug bounty platform, Marten's career is a masterclass in building innov…
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In the first episode in Season 2 of The Lean AI Podcast, host Ben Hafele is joined by Chris Reitz, a seasoned product management professional and AI educator. Together, they discuss the importance of cultivating AI use cases through problem-focused approaches, avoiding "magical thinking" in AI initiatives, and making strategic small bets rather tha…
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In this episode of The Eric Ries Show, I'm joined by Celine Halioua, founder and CEO of Loyal, a groundbreaking biotech startup developing drugs to extend dogs' healthspan and lifespan. Celine's journey combines her passion for animals with a bold scientific mission that looks beyond pets to potentially transform human longevity as well. Our conver…
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In this episode of The Eric Ries Show, I sit down with Daniel Dines, the Founder and CEO of UiPath, a company that started in robotic process automation (RPA) and is now making a bold shift into agentic AI. Dubbed “the boss of bots” by Forbes, Daniel has led UiPath from its humble beginnings to a $6.65 billion company that’s reshaping the future of…
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In this episode of The Eric Ries Show, I’m joined by Alyssa Ravasio, CEO and Founder of Hipcamp. Hipcamp is the platform that has revolutionized camping, with a mission to “get more people outside.” By making it easier for people to find camping on public lands—and then expanding to include private lands—Hipcamp significantly increased the supply o…
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In today’s episode of The Eric Ries Show, I’m joined by Gagan Biyani, Co-Founder and CEO of Maven, a platform that’s redefining online education with cohort-based courses. Before Maven, Gagan co-founded Udemy, now one of the largest online education marketplaces, and Sprig, a meal delivery startup. Gagan started his entrepreneurial journey at just …
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In today’s episode ofThe Eric Ries Show, I am joined by Luis von Ahn, CEO and co-founder of Duolingo. With Duolingo, his mission was simple: make language learning accessible to everyone—not to build a for-profit company. Fast forward to today, and Duolingo has grown into a $17 billion business with a reported 90% of the online daily active users i…
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In this episode of The Eric Ries Show, I sit down with Craig Newmark, the founder of Craigslist—one of the internet’s most influential platforms. Despite its massive impact, Craigslist has remained intentionally minimalist, resisting the hyper-monetization strategies common in tech. Craig attributes his success to being in the right place at the ri…
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In this episode of The Eric Ries Show, I’m joined by Amir Nathoo, Co-Founder and CEO of Outschool, an education platform offering live online classes for K-12 learners. Amir’s own childhood inspired Outschool—while he went to traditional schools, his parents always encouraged his self-driven coding projects at home. Outschool is about empowering ki…
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In this episode of The Eric Ries Show, I’m joined by Emil Eifrem, Co-Founder and CEO of Neo4j, an open-source graph database. Neo4j enables organizations to unlock the business value of connections, influences, and relationships in data. In our conversation today, we talk about the following topics: • The origin story of Neo4j and why they chose op…
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"Why are we trying to fight all of this?" The pace of technological advancement outstrips our ability to adapt, a phenomenon captured by MarTec's Law. In this episode, Dr. Chris Mühlroth and Scott Brinker, VP of Platform Ecosystem at HubSpot delve into the complexities of technological advancement and its implications for organizations. They discus…
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In this episode of The Eric Ries Show, I’m joined by Iman Abuzeid, the co-founder and CEO of Incredible Health, a platform transforming how healthcare systems hire nurses. After earning an MD, Iman pivoted to business and technology. She spent some time working in New York before enrolling at The Wharton School, where she earned her MBA. After grad…
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In this episode of The Eric Ries Show, I’m joined by Siqi Chen, a four-time founder and the CEO and CFO of his latest venture, Runway. Runway offers a modern, user-friendly platform for financial modeling, headcount planning, and departmental budgeting—proudly branding itself as “the finance platform your team doesn’t hate.” With its distinctive ma…
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In the dynamic season #1 finale of The Lean AI Podcast, host Ben Hafele is joined by Eric Ries—bestselling author of The Lean Startup and The Startup Way, and creator of the transformative Lean Startup methodology. Known for redefining how companies innovate, Eric shares actionable strategies to develop AI-powered solutions that drive real impact. …
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This week I had a great conversation with Russ Peloquin, Managing Partner of LifeSci Catalyst Partners. We dive into Russ's unique journey from aspiring exterminator (yes, you read that right!) to leading life science entrepreneur, discussing his extensive experience in commercialization, mergers, and acquisitions. Russ shares invaluable insights o…
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Join renowned aging researcher Dr. Aubrey de Grey in an enlightening conversation about the science and societal impact of anti-aging technologies. Explore the concept of aging as a medical problem, the interplay of genetics and lifestyle, and groundbreaking research at the LEV Foundation aimed at reversing the effects of aging. Discover how biolog…
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Rodney Brooks has spent his entire life at the intersection of robotics, computers, and AI. When the Roomba vacuum cleaner launched in 2002, his company, iRobot, brought all three into millions of people’s homes. iRobot had already succeeded with robots for space exploration, mine detection, search missions, and military applications. However, afte…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Mike Hollinger, Distinguished Engineer at IBM and President of the Austin AI Alliance. Together, they explore the critical importance of understanding user intent, leveraging organizational data effectively, and avoiding common pitfalls in AI implementation. Website: ibm.com/desig…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Chris Withers, a seasoned leader known for his transformative roles in data and AI at BT Group, EY, and IBM. Together, they discuss deploying AI tools to enhance productivity and spearhead initiatives, the challenges of collecting "ground truth" data, and the value of testing assu…
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The story of the digital content-sharing platform Gumroad challenges every aspect of the received wisdom about building successful companies. After it almost went under, founder and CEO Sahil Lavingia decided to pare down to the essentials rather than walk away. Then he took his characteristic counter-intuitiveness further and left Silicon Valley f…
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This week I chatted with Renee Williams, Founder and Managing Partner at Williams Biotech Consulting. Renee is a seasoned fractional Chief Business Officer (CBO) for small and growing biotechnology companies. Renee shares her career path, insights into helping biotech startups secure funding and navigate partnerships, and the importance of adaptabl…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Christina Mongan, Global Director of AI Practice at Unisys. Together, they discuss driving successful AI transformation in large organizations. Christina shares insights on prioritizing business outcomes, creating a human-centered approach to AI, and avoiding common pitfalls in AI…
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This week, I spoke with Natalie Nairn, co-founder and CEO of Cyclera Therapeutics. Natalie is also a Termeer Fellow, and listeners of this podcast know how much I love the Termeer Foundation. We discuss her transition from chemical engineering to biomedical applications. She describes her unexpected path into the fun and volatile startup space, whi…
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The story of Groq, a semiconductor startup that makes chips for AI inference and was recently valued at $2.8 billion, is a classic “overnight success that was years in the making” tale. On this episode, I talk with founder and CEO Jonathan Ross. He began the work that eventually led to Groq as an engineer at Google, where he was a member of the rap…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Dr. Meeta Vouk, AI Product and Strategy Leader. Together they discuss essential strategies for executives navigating AI, including the importance of starting with clearly defined problems, establishing robust governance frameworks, and fostering cross-functional collaboration.…
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In this thought-provoking episode, we sit down with Nic Jones, a former executive who made the bold decision to step away from a high-powered career in media to drive buses. Jones, whose past roles spanned influential positions at Moshcam, Pureprofile, Nine, Yahoo, News Corp, Publisis, and Vevo, shares the experiences and reflections that led him t…
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In this episode, I had an engaging conversation with Stacie Frye, co-founder and Chief Commercial Officer of StimulusBio, a life sciences commercialization and venture studio for biotech startups. We discussed how StimulusBio aids startups in operational and commercialization aspects, leveraging Stacie's unique journey across marketing, chemical en…
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Wendy Gonzalez is the CEO of Sama, an ethical AI company that provides training and jobs with equitable pay and benefits to those who face the greatest barriers to stable employment. Among the companies it provides AI development data to are Microsoft, Ford, Walmart, Google, and many others. But before its current incarnation, Sama was a very diffe…
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Introduction: In this episode, we dive into the world of Lean Startup, 13 years on from its inception, and explore the challenges and nuances of applying it within large corporations. While Lean Startup principles are widely taught, executing them in established corporate environments often leads to failure. Our guest, Ben Hafele from Lean Startup …
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Mike Schubert, Vice President of Technology at Unum. Together, they discuss Mike’s four-step framework for successful AI initiatives, the importance of grounding AI efforts in real business needs, and the value of learning from both successes and failures.…
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"AI is an amazing tool for brainstorming, giving ideas, and being a thought partner, but even when machines can do better than humans, we still like the story behind it. The human behind the machine is what really matters." In this episode, we exchange withMike Todasco, formerSenior Director of Innovation at PayPal and current AI Fellow at San Dieg…
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This week, I had an insightful conversation with David Sans, PhD, FAARM, MBA, who heads healthcare investment banking at EF Hutton. We discussed the intricacies of different Public Offering strategies, including micro IPOs, which offer a unique avenue for biotech companies. David provides a deep perspective on the strategic implications of IPOs for…
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Sal Khan arrived at the idea for Khan Academy truly organically. While working at a hedge fund, he took time in the evenings to tutor a younger cousin in math over the phone. Soon, a family tutoring network was in place, and from there, it was only a few years before Sal realized that the kind of help he was giving his family could – and should – b…
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This week I had a great conversation with Iva Toudjarska, founder and CEO of Zeal Therapeutics. From earning a PhD in molecular biology to a solid scientific career at Alnylam, to working in venture capital, to selling a successful SaaS company, Iva’s career that’s set her up well to enjoy this new challenge – founding a baby biotech. Her expertise…
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In this episode of The Lean AI Podcast, host Ben Hafele is joined by Vivek Mahapatra, Vice President of Go To Market at Salesforce AI. Together they discuss the strategic implementation of AI in business, successful AI use cases in customer service, and common pitfalls organizations face.By Lean Startup Co
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This week I had a fun conversation with Jason Cordeiro, Chief Operating and Innovation Officer at MassBio. We dissect MassBio's newly announced five-year strategic plan that includes a multi-pronged set of initiatives aimed at advancing the biotech industry. From supporting early-stage startups to advocating for policy changes and fostering talent …
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"Strategic foresight, as I define it, is really about the capability of organizations to, in a systematic way, create superior positions in markets of the future." In this episode, Dr. Christian Mühlroth engages in a discussion with Professor Dr. René Rohrbeck, a leading expert in strategy foresight and innovation, Professor of Strategy and EDHEC &…
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Founded in 2011 in the distinctly non-Silicon Valley location of Columbia, Missouri, software integration company Zapier hit profitability in 2014. Today, the company is valued in the billions, and is poised to keep thriving as AI becomes a normal part of everything we do online. My guest on this episode of The Eric Ries Show is co-founder and CEO …
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