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Ama Steps Forward Podcasts

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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance ...
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Many practices reduce unnecessary messages by suppressing the delivery of “thank you” messages into clinician inboxes. With this switch, the care team does not have to manage patient replies that express gratitude or acknowledge understanding (but require no further action). There is no regulatory obligation to respond to every patient portal messa…
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You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden causes of early aging like mitochondrial dysfunction, leaky gut, and chronic inflammation. Watch this episode on YouTube for the full video experience:…
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93% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap to reboot your metabolism, escape the sugar-burning trap, and reignite your fat-burning engine for good. Watch this episode on YouTube for the full vi…
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You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do instead. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with performance-dr…
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Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You’ll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxins disrupting your hormones, brain, mitochondria, and overall health. This is a masterclass in biohacking from two experts who’ve spent decades resear…
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Dr. Kim Smolderen, licensed clinical psychologist and outcomes researcher, Associate Professor of Medicine and Psychiatry at the Yale School of Medicine, Co-founder of the American College of Cardiology (ACC) Cardiovascular Psychology workgroup, and a recognized expert in vascular disease, discusses the critical but often underrecognized intersecti…
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Your anti-aging skincare routine might be secretly aging you faster. In this episode, you’ll uncover how trending skincare products including vitamin C serums, harsh exfoliants, and blue light therapies can damage your skin’s mitochondria, accelerate senescence, and trigger systemic inflammation. You’ll learn how to reverse this damage, support cel…
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Most supplements don’t work, and this episode reveals why. You’ll learn how to stop wasting money on “expensive pee,” how to spot marketing lies on labels, and which ingredients actually move the needle for energy, focus, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asp…
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Psychedelic therapy is on the verge of reshaping mental health, trauma healing, and human consciousness. This episode reveals what’s really happening behind the scenes at the FDA, inside pharmaceutical companies, and within the global movement to legalize MDMA-assisted therapy. Watch this episode on YouTube for the full video experience: https://ww…
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Dr. Greenawald, Interim Chair of Family Medicine at Carilion Clinic in Virginia, explores the concept of "autonomy" for physicians, offering his personal perspective while highlighting how the meaning of autonomy can vary for different physicians depending on their context and environment. Dr. Greenawald also discusses practical strategies for phys…
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You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boosting mitochondria, and rebuilding your biology from t…
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Your brain is under constant assault from devices you use every day. This episode reveals the hidden effects of 5G on brain function, cognitive performance, and nervous system stress, along with the science-backed method that neutralizes the damage. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR …
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Dr. Rob Saper, Chair of the Department of Wellness and Preventive Medicine at Cleveland Clinic, explains what it means to fully disconnect from your work as a practicing physician, and discusses practical, actionable steps to do so. Explore the Value of Feeling Valued Playbook: https://bit.ly/43BX9Vk Explore the "Real PTO" for Physicians Toolkit: h…
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Most people think 10,000 steps a day is the gold standard for health, but it’s outdated, inefficient, and often damaging. In this episode, you’ll discover a smarter, faster way to walk for longevity, fat burning, and total body resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave …
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This episode dives into the brutal, mind-altering experience of spending 60 days alone in Antarctica, and how extreme suffering became a catalyst for spiritual awakening, peak performance, and deep inner peace. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with elite a…
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Dr. Tiffany Moore Simas, Medical Director for Lifeline for Moms, and Obstetric Engagement Liaison for the Massachusetts Child Psychiatry Access Program (MCPAP) for Moms, explores the opportunities and challenges of maternal behavioral health-focused care models while emphasizing the importance of integrating behavioral health as a core component of…
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This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Aaron Alexander, a world-renowned h…
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This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mona Sharma, a renowned Ayu…
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Dr. Vincent Liu, Chief Data Officer at The Permanente Medical Group, an AMA health system group member, shares how they are defining success in Augmented Intelligence (AI) governance. He discusses how they're aligning AI initiatives with strategic goals, scaling successful pilots like ambient documentation, managing emerging risks, and building tru…
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You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours. Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Sc…
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Your brain runs slow when it’s running on the wrong fuel. In this episode of The Human Upgrade, Dave Asprey sits down with Geoffrey Woo, Stanford-trained computer scientist and founder of Ketone-IQ, to reveal the high-performance brain fuel once reserved for Special Forces and elite athletes. Discover how ketones helped operators in combat zones sh…
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Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You’ll learn ho…
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Physicians can often cut out redundant information, only documenting the medically necessary and appropriate history. By encouraging all physicians to create standardized notes with the same look and feel, your clinical team will reduce their cognitive burden and spend less time scrolling. Explore the Simplified Outpatient Documentation and Coding …
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Your brain has a gear you’ve never touched. Psychedelics can shift you into it. In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science. You will le…
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Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it. In this episode of The Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixe…
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Your environment is rewiring your hormones, fertility, and long-term health without your consent. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking…
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Dr. Alvin Liu, an endowed professor of the AI Oversight Team and inaugural director of the James P. Gills Jr., MD, & Heather Gills Artificial Intelligence Innovation Center at Johns Hopkins Medicine, discusses Johns Hopkins Medicine’s journey with Augmented Intelligence (AI) governance, involving end users to provide feedback, and some critical fac…
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What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why po…
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What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition? In this episode of The Human Upgrade, Dave Asprey talks with Dr. Brandon Crawford, a leading neurotherapist and founder of 528 Innovations, about the emerging science of laser therapy for the brain and body. You’ll learn how light—when precisely p…
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Dr. Srinivasan Suresh, Chief Information Officer, Chief Medical Information Officer, and Vice President of UPMC Children’s Hospital of Pittsburgh discusses key steps for success in Augmented Intelligence (AI) governance, including establishing leadership and structure, aligning AI initiatives with strategic goals, developing policy, ensuring proper…
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What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution? In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science of cellular intelligence. Together, they reveal how your mitochondria, microbiome, and genetic memory do far more than support survival—they actively…
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You’ve probably heard of HIIT—but have you heard of “REHIT?” This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained e…
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Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy…
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Both patients and care teams need to understand that communication through the patient portal should not replace a physician visit, whether telehealth or in-person. Offer your patients a handout describing the best way to use the portal. Be open and honest with patients if they are sending too many messages. Explore the Patient Portal Optimization …
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Most people run from stress. The world’s highest performers run toward it. Sébastien Page manages over $500 billion in global assets. He’s the CIO of one of the world’s largest investment firms, and he wrote The Psychology of Leadership while living under relentless pressure. His secret? He doesn’t avoid stress—he uses it as a tool for performance,…
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Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you. But what if there was a way to take it back… and hack the system? In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to explore a radical shift in the way…
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Dr. Jessi Gold, inaugural Chief Wellness Officer for the University of Tennessee (UT) System, associate professor of psychiatry at the University of Tennessee Health Science Center (UTHSC), practicing outpatient psychiatrist, and author of the book, How Do You Feel?: One Doctor's Search for Humanity in Medicine, discusses her experience with burnou…
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If your brain feels foggy, your mood swings like a pendulum, or your cravings seem to control you—this episode will flip what you think you know about your body and your mind. Because what if your thoughts… aren’t really yours? In this mind-altering episode of The Human Upgrade, Dr. Steven Gundry reveals a startling new theory: your gut microbiome …
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If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong? For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real…
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What if you could rewrite the code of your personality—on command? Not just cope with anxiety, overthinking, or social exhaustion… but delete the traits holding you back and install better ones? This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods…
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Dr. Gino Somers, Chief of the Department of Paediatric Laboratory Medicine from Hospital for Sick Children (SickKids) Toronto, shares his experience adapting the AMA STEPS Forward® After a Physician Suicide Toolkit to meet the unique needs of his organization. He discusses the challenges of addressing physician suicide, the importance of creating a…
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Your brain isn’t broken—it’s underpowered. Energy crashes, poor sleep, brain fog, and emotional reactivity don’t just happen. You’re running on low voltage, and your mind pays the price. In this episode, Dave sits down with Dr. Patrick Porter, founder of BrainTap, to reveal how to reprogram your brain using light, sound, and guided visualization—no…
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You think you’re helping your kid. You clear the path. You smooth the bumps. You make sure they never feel too sad, too bored, too uncomfortable. It feels like love. But what if it’s making them weak? In this episode, Dave Asprey sits down with bestselling author, TED speaker, and resilience expert Jennifer Cohen to reveal how today’s parenting nor…
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Dr. Raymond Tsai, AMA member and Vice President of Advanced Primary Care at the Purchaser Business Group on Health (PBGH), explains why it is in an employer's best interest to prioritize providing their employees with high-quality, whole-person care. He also provides insights into PBGH’s ongoing efforts to help employers access their model of advan…
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For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging? In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in m…
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For nearly a century, scientists believed we had discovered ALL of the essential fatty acids the human body needs. But what if they were wrong? Stephanie Venn-Watson, a veterinary epidemiologist and longevity researcher, joins Dave to reveal a groundbreaking discovery—a newly identified essential fatty acid, C15, that may hold the key to healthier …
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When a colleague is experiencing a crisis or is at risk of suicide, you don’t have to be an expert to offer help. Peer support is a crucial component in ensuring the well-being of colleagues and reducing the risk of suicidal ideation. Often, reaching out with a simple recommendation to talk with a mental health professional can make a huge differen…
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You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammati…
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You think, you feel, you are—but what if your consciousness isn’t just in your brain? What if reality itself is shaped by something beyond the physical? In this episode, Mark Gober—author, consciousness researcher, and former Silicon Valley banker—joins Dave Asprey to challenge everything you think you know about the mind, reality, and human potent…
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Dr. Suzanna Fox and Yasemin Moore from Advocate Health, which achieved Joy in Medicine Gold for the Southeast region in 2023, discuss the Best Place to Care Initiative and its use of STEPS Forward® resources and Organizational Biopsy® results to provide well-being care for their physicians and Advanced Practice Providers (APPs). Explore the AMA Org…
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