Best The Chimp Paradox Podcasts (2025)

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135. The get rich quick trap - Why slow and boring wins the money race 39:23

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2d ago39:23

39:23

People confuse luck for skill when it comes to investments. Your path to wealth isn’t a sprint; it’s a patient, consistent marathon. We tear down the seductive fantasy of getting rich quickly, and reveal why those instant-success pitches are almost always traps preying on your fears of missing out and your desire to get rich quickly. We share why w…

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How to communicate results from adaptive studies simple, but still correct 24:20

8d ago24:20

24:20

A Conversation with Kaspar Rufibach Why You Should Listen: ✔ You need clear, defensible language for papers, conferences, and labels when your study had interims and stopping rules. ✔ You’ll learn practical rules-of-thumb for when “naïve” estimates are okay—and when to adjust. ✔ You’ll hear what regulators typically focus on vs. what patients and c…

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134. Finding happiness through ancient wisdom, the Epicurus way 48:54

9d ago48:54

48:54

Stop chasing the next big purchase and start finding genuine contentment. The world tells us that more money, more stuff, and a higher status equal happiness, yet we only feel more anxious and unfulfilled. Enter the ancient philosopher Epicurus, who flips the script on modern consumerism. We discuss how the Epicurean pursuit of tranquility and free…

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Introduction to adaptive designs and ICH E20 29:36

15d ago29:36

29:36

A Conversation with Kaspar Rufibach Why You Should Listen: If you’ve ever wondered what adaptive designs really are, when they make sense, and how ICH E20 will influence our work as statisticians, this episode will give you a clear, practical overview. You’ll learn: ✔ Why adaptive designs often save valuable time—and what organizational barriers ke…

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133. Five ways to reset holiday expectations 28:24

16d ago28:24

28:24

The holidays are meant to be about joy, but somewhere along the way, we've let them become a source of stress, guilt, and financial and emotional strain. We’ve all felt the pressure to overspend, over-commit, and keep up with picture-perfect social media feeds. We offer a practical antidote to the madness, with five actionable ways to reset your ho…

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132. The Art of the Return - Get your money back! 56:54

23d ago56:54

56:54

This is your masterclass in returns and reclaiming your money with grace and strategy. We reveal why returns matter and how to turn a common headache into a financial win. We go beyond the simple act of taking something back and share how to approach shopping with an "exit strategy" and that things are often negotiable. Listen to some of our crazie…

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131. What is rebalancing and should I be doing it? 26:18

1M ago26:18

26:18

Sometimes, your investment portfolio needs a course correction to stay safe and on track with your personal allocation strategy. We tackle the essential, yet often ignored, financial tune-up known as rebalancing. Learn exactly what rebalancing is, why this simple process is about managing risk (not chasing returns), and the practical steps to imple…

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Leadership, Influence & Presenting: Human Skills That Make Statisticians Effective 36:15

1M ago36:15

36:15

A conversation with Alexander Schacht and Alun Bedding Why You Should Listen: ✔ Hear my personal reflections on 456 episodes and the evolution of this podcast. ✔ Learn a simple, values-based view of leadership that applies no matter your level. ✔ Discover how to influence people—not departments—and build trust. ✔ See why contextual teaching beats g…

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130. The Chimp Paradox: Why you spend when you know you shouldn’t 35:49

1M ago35:49

35:49

Ever wonder why you make financial decisions that go against your better judgment? This episode delves into The Chimp Paradox, a powerful psychological model by Dr. Steve Peters that explains the constant tug-of-war between your emotional "chimp" brain and your rational "human" brain. We'll explore how this internal conflict often leads to impulsiv…

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129. Are you a HENRY? Escaping the traps so you can build wealth 1:04:31

1M ago1:04:31

1:04:31

Are you earning big but feeling broke? You're not alone. Welcome to the world of the H.E.N.R.Y.—High Earner, Not Rich Yet. This growing demographic of six-figure earners finds themselves in a financial paradox, with significant income but little to show for it in savings or investments. This episode dives into the two primary culprits behind the HE…

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Top 8: The Single Arm Studies and What are the Alternatives? 45:32

2M ago45:32

45:32

Interview with Anja Schiel Why You Should Listen: f you’ve ever wondered whether single-arm studies are “good enough” for regulators or HTA bodies, this episode will challenge your assumptions. Anja Schiel, one of Europe’s leading voices at the regulator–HTA interface, explains why comparisons matter, where single-arm designs break down, and what s…

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128. What is the good life? And how expensive is it? 58:57

2M ago58:57

58:57

Is the good life about luxury goods and expensive travel, or is it something much simpler yet profound? We dissect what a "good life" truly is, from the dictionary definition to Morgan Housel's core elements of happiness, and we'll reveal the simple, actionable steps you can take to start funding a life rich in more than just dollars. We explore wh…

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Top 7: How to work with a physician within Pharma to become a valuable partner 26:40

2M ago26:40

26:40

Discussion with Benjamin Piske and Alexander Schacht Why You Should Listen: Working with physicians isn’t always easy. Different mindsets, expectations, and communication styles can get in the way. In this episode, you’ll hear how to: ✔ Build trust and respect with physicians in pharma ✔ Communicate effectively across disciplines ✔ Know when to sup…

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127. Home warranties - A safety net or a money pit? 45:54

2M ago45:54

45:54

Are home warranties worth it? We answer this question and more. We break down how home warranties work, their pros and cons, and considerations for your primary home versus a rental property. We share personal experiences with home warranties and offer our tips on how to shop for and maximize the benefits of a home warranty if you decide to purchas…

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Top 6: What is EU HTA and why should statisticians care? 36:08

2M ago36:08

36:08

Interview with Lara Wolfson and Anders Gorst-Rasmussen Why You Should Listen: ✔ EU HTA is becoming reality: Joint Clinical Assessments begin soon with oncology/ATMPs and will expand to all medicines over the next years. ✔ Statisticians are central: Re-analyses, indirect comparisons, RWE, and quality-of-life analyses will be required—often beyond wh…

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126. The Real L-Word - Why Limits are your new best friend 33:46

2M ago33:46

33:46

Setting limits can get a bad rap, but limits are actually the key to a more joyful and abundant financial life. We redefine budgeting and setting limits not as a thing of deprivation, but as a path to peace, and share how setting healthy financial limits can reduce decision fatigue, build powerful discipline, and surprisingly, create more freedom a…

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Top 5: The analysis of adverse events done right 52:45

2M ago52:45

52:45

Interview with Kaspar Rufibach & Jan Beyersmann What You’ll Learn: ✔ Why analyzing adverse events differently from efficacy endpoints creates problems. ✔ How differing follow-up times and censoring bias AE results. ✔ The role of the Aalen–Johansen estimator and why it should be standard practice. ✔ What the SAVVY collaboration achieved by uniting p…

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125. The psychology of debt - How to stay motivated while paying off debt 1:07:08

2M ago1:07:08

1:07:08

Let's make paying off debt a little more fun and a little less of a slog. We deep dive into the psychology of debt repayment and offer some of the more enjoyable ways to stay motivated and on top of your debt payoff journey. We’re moving beyond standard budgets and interest rates to discuss the power of “hacking” your brain, leveraging the principl…

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124. Listener Q&A with Andrew - US vs. international investing, 457b plans, roth conversion ladders, when to stop contributing to your 401k, tracking HSAs expenses, and more! 53:22

3M ago53:22

53:22

This week, Andrew and I answer your money questions about the nitty-gritty of retirement planning, complexities of early retirement strategies, roth conversion ladders, what to do with your cash, common investing misconceptions, US vs. international stock investing, and more. Get the full show notes, show references, and more information here: http…

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Replay: R vs SAS - which is the better tool in pharmaceutical research 42:29

3M ago42:29

42:29

Interview with Sam Gardner & Thomas Neitmann What You’ll Learn: ✔ How Thomas and Sam were first introduced to SAS and R — and how their early experiences shaped their preferences. ✔ Key differences in learning curves and the resources available for beginners. ✔ How each tool fares in day-to-day work and long-term maintainability. ✔ Strengths and we…

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123. A dopamine menu - 20 ways to feel good without spending money 50:09

3M ago50:09

50:09

Next time you get the urge to make a purchase, try one of these things to get a free or low-cost dopamine hit. We’re exploring the science of dopamine and how our brains are hooked on the thrill of a new purchase. Instead of letting the impulse to shop take over, we share ideas to create your own dopamine menu that will deliver the same feel-good c…

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Replay: The Chimp Paradox 41:35

3M ago41:35

41:35

Interview with Stuart McGuire What You’ll Learn: ✔ How to recognize when your “chimp” is in control — and what to do about it ✔ The difference between emotional, rational, and programmed brain responses ✔ How to manage anxiety and fear in high-stakes situations like meetings and presentations ✔ Why we often overwork out of tribal guilt — and how to…

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122. This is your brain on debt - Let’s stop normalizing debt 1:13:25

3M ago1:13:25

1:13:25

Debt has become a quiet, accepted part of our lives, but what if we stopped seeing it as normal? We challenge the narrative that debt is an inevitable part of modern life. We dissect how societal pressures, easy access to credit, and a culture of instant gratification lead us down a path of unintentional debt. This isn't just about the numbers; it'…

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Replay: Is data science something for you? 26:19

3M ago26:19

26:19

Interview with Yannis Jemiai & Rajat Mukherjee What You’ll Learn: ✔ How two leading statisticians transitioned into data science ✔ The key differences (and overlaps) between data science, statistics, big data, and machine learning ✔ Why data science is more than hype—and why statisticians are needed more than ever ✔ The role of visualization and st…

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121. Mid-year spend review with Liz, Andrew, Erica, and Greg 1:23:30

3M ago1:23:30

1:23:30

Four families share what they spent in the first half of 2025. We’ve had renovations, vacations, celebrations, donations, and more! Listen to find out who’s spent the lowest and highest this time, it is not who you’d guess. We are still big fans of intentional spending and not spending more than you earn, and we’re all still following those best pr…

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Replay: Things we would like to have known before we started with RWE 48:53

4M ago48:53

48:53

Interview with Rachel Tham What You’ll Learn: ✔ Why “index date” is more complicated than it sounds ✔ Common mistakes around exposure definitions ✔ The importance of understanding how RWE data is generated ✔ What programmers should know about timing, variables, and algorithms ✔ Why project management in RWE must be iterative and stakeholder-driven …

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120. The humility hack - how less ego can lead to more money 54:39

4M ago54:39

54:39

Humility can be your most powerful financial tool, so learn how to check your ego and enhance your financial well-being. Cultivating and improving your humility can be transformative in building lasting wealth and a truly fulfilling life. Get ready to ditch the "keeping up with the Kardashians" effect and embrace actionable strategies that redefine…

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119. The intersection of mental health and financial wealth 57:35

4M ago57:35

57:35

We unpack the powerful, often perplexing, and always present link between your mental health and your personal finances. In a world of economic uncertainty and rising costs, it's more crucial than ever to understand that financial wellness isn't just about what's in your wallet; it's about what's in your head. Join us as we explore how financial wo…

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118. Is more expensive better? When it pays to pay more. 1:21:50

4M ago1:21:50

1:21:50

We explore the complex relationship between cost and quality, debating whether "more expensive is always better." We deep dive into the fascinating psychology, sneaky marketing tactics, and real-world financial implications behind our purchasing decisions. We discuss a range of products, including mattresses, groceries, clothing, and cosmetics. We …

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AI and Statistics Start-ups: Opportunities and Challenges 43:32

4M ago43:32

43:32

Keynote by Manjari Narayan | The Effective Statistician Conference 2024 What You’ll Learn: ✔ Why the 21st century is truly the "century of biology" and what that means for statisticians ✔ The untapped opportunity for statisticians to innovate before clinical trials begin ✔ How AI-guided experiments are changing drug discovery—and the statistical ch…

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117. How to make more money - career advice, asking for a raise, side hustles, and more 1:07:31

4M ago1:07:31

1:07:31

Cutting expenses and being frugal can significantly boost your financial future, but it’s only one part of the wealth-building equation. Sometimes, the best defense is a good offense—in this case, earning more money. In this episode, we tackle the often intimidating topic of how to increase your income, covering everything from being an outstanding…

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Combining RCT and RWD – applications in rare diseases and practical recommendations 47:05

5M ago47:05

47:05

Keynote by Prof. Tim Friede | The Effective Statistician Conference 2024 What You’ll Learn: ✔ When and how to combine RCTs with real-world data (RWD) ✔ The CJD study: lessons from combining registry and trial data ✔ Hierarchical Bayesian meta-analysis and shrinkage estimators ✔ Robustness of these approaches in the face of heterogeneity ✔ Practical…

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116. Our favorite financial books and podcasts, with a few surprising gems! 1:08:42

5M ago1:08:42

1:08:42

The sheer volume of free and high-quality financial content accessible to us is truly impressive, yet it can also be incredibly overwhelming. That's why we're sharing our absolute favorites with you in this episode, cutting through the noise to bring you the books and podcasts that have genuinely transformed our financial thinking. Discover why cla…

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Real-World Evidence vs. Randomized Trials: Can We Emulate Accuracy? 52:00

5M ago52:00

52:00

Keynote by Prof. Sebastian Schneeweiss | The Effective Statistician Conference 2024 What You’ll Learn: ✔ The motivation behind emulating randomized trials using real-world data ✔ How claims and EHR data can support regulatory-grade evidence ✔ What makes a trial emulation good vs. suboptimal ✔ The role of adherence, measurement limitations, and data…

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115. Mind over money: How Stoicism can transform your finances with Kathleen from Minimalish Mom 48:20

5M ago48:20

48:20

Think ancient philosophy has nothing to do with your bank account? Think again! This episode brings a powerful dose of Stoic wisdom to your modern financial world. Joined by special guest co-host Kathleen from the Minimalish Mom podcast, we're uncovering how the timeless principles of Stoicism, like focusing on what you can control and accepting wh…

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The Power of Networking 16:32

5M ago16:32

16:32

Discussion with Alun Bedding What You’ll Learn: ✔ Why networking is about curiosity—not small talk ✔ How to set clear intentions for networking at events ✔ The three biggest myths that hold people back from networking (and how to overcome them) ✔ Practical tips for PSI Conference attendees to network with confidence ✔ The real-world value of buildi…

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114. The inside out approach to financial freedom 1:09:48

5M ago1:09:48

1:09:48

Ever felt like you're climbing someone else's ladder, or that your financial decisions are driven by what everyone else is doing? This episode introduces the powerful concept of "Inside Out" living, a philosophy that inspired the very name of this podcast. We'll explore why shedding societal expectations and reconnecting with your true desires is t…

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Inclusion for All: Rethinking Success, Neurodiversity, and Accessibility in the Workplace 36:46

5M ago36:46

36:46

Featuring Alun Bedding and Emma Crawford Learnings You’ll Gain From This Episode: ✔ Why inclusion is everyone’s responsibility—not just HR’s ✔ The difference between “reasonable adjustments” and “success enablers” ✔ How AI tools can support accessibility and productivity ✔ The hidden challenges behind late diagnoses of neurodivergence ✔ Why leaders…

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113. The real reasons you’re not improving your finances, and how to fix them 40:55

5M ago40:55

40:55

Ready to finally take control of your finances? We dive into the common roadblocks that hold us back from reaching our financial goals. Discover why your mindset might be your biggest obstacle, the power of knowing your numbers, and how to navigate the crucial relationship dynamics that impact your money. It's time to stop making excuses and start …

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112. Withdrawal strategies in early retirement - A flexible strategy and account playbook to fund your retirement 49:14

5M ago49:14

49:14

You've diligently saved and invested, and now comes the pivotal question: How do you live off those funds, especially in early retirement? We discuss the various withdrawal strategies, going beyond the basic 4% rule to explore dynamic and flexible approaches. Learn how to consider tax implications, access retirement accounts early without penalties…

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Daily updated systematic literature reviews - the future of oncology 22:57

6M ago22:57

22:57

Interview with Anna Forsythe Why You Should Listen: ✔ Discover how SLRs are evolving through automation and AI ✔ Learn how real-time data can improve cancer treatment decisions ✔ Understand the balance between innovation and clinical responsibility ✔ Hear about a tool that could change the way guidelines and clinical practice align ✔ Be inspired by…

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111. How to handle a windfall - protect your future fortune 59:13

6M ago59:13

59:13

Whether it's a lottery win, an inheritance, or a work bonus, a windfall can feel like a dream come true, but mishandling it can quickly turn it into a financial nightmare. We dive into the crucial first steps you need to take, understanding the tax implications, setting meaningful financial goals, and creating a solid plan to protect and grow your …

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A novel approach for finding predictive biomarkers 35:39

6M ago35:39

35:39

Interview with Julia Geronimi and Pavel Mozgunov Why You Should Listen: ✔ You’ll learn a new method that’s both statistically sound and easy to implement ✔ You’ll see how to pre-specify your analysis strategy for biomarker evaluation ✔ You’ll understand how to get more value out of small sample sizes ✔ And you’ll come away with a fresh appreciation…

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110. Raising financially responsible kids - Setting money expectations at every age 1:35:50

6M ago1:35:50

1:35:50

Raising kids is tough, but raising financially responsible and aware kids is quite simple, and you can do it! This week, I am joined by a special teenager co-host, my 16-year-old step-daughter Maddie, as we discuss how and when to set financial expectations with kids. From limiting the volume of toys to comparison shopping to the realities of car i…

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A Webinar Recording: Redefining the Role of Statisticians in a World of Real-World Data and AI 51:48

6M ago51:48

51:48

Webinar with Yannis Jemiai, Flaminia Chiesa, and Benjamin Piske ✔ Learn how statisticians can step into leadership roles as data science becomes more strategic. ✔ Understand the impact of AI, real-world evidence, and decentralized trials on clinical trial design. ✔ Hear practical advice for staying relevant in the age of reimagined RCTs. ✔ Get insi…

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109. Andrew's Big News - What's next and why it's not early retirement 56:50

6M ago56:50

56:50

Buckle up for some exciting news from co-host Andrew! Andrew shares what is next for him after 25 years in Corporate America, and it might not be what you think! Andrew shares the journey that led him to this pivotal moment, from early FIRE aspirations to pandemic-fueled perspective shifts to navigating his next chapter. Andrew explores intriguing …

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RWE and JCA - how do they go together 20:21

6M ago20:21

20:21

Interview with Katrin Kupas What You’ll Learn in This Episode: ✔ What the JCA is and why it changes how we plan evidence generation ✔ When and how RWE can help answer comparator questions in HTA ✔ The risks of non-randomized comparisons—and how to mitigate them ✔ Why we need an integrated evidence plan early in development ✔ How tools like ROBINS-I…

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108. Reclaim your time (and money) - Actionable strategies for the overwhelmed 37:06

6M ago37:06

37:06

It takes time to improve your finances, and you're not alone if you feel like there’s never enough. We’re diving into the reality of time constraints, with actionable strategies for the busy and overwhelmed. Discover how to use Parkinson’s Law for good, the high cost of inaction, why you should focus on the important vs. the urgent, the importance …

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Why and how you can promote more students become statisticians 29:32

7M ago29:32

29:32

Interview with Emma Crawford and Alex Spiers ✔ Why STEM outreach is so important for the future of our industry ✔ How your company, community, and even your own career can benefit from getting involved ✔ The challenges students face (especially girls and those from underserved areas) in seeing themselves in STEM ✔ How PSI’s Schools Outreach team ca…

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107. Finfluencers - Yuck! Wait!? Is that what we are? 1:11:00

7M ago1:11:00

1:11:00

When I grew up, finding financial opinions and advice felt hard. Now we’re saturated with it, but is that a good thing!? We discuss the murky waters of social media financial influencers, aka finfluencers, and explore the good, the bad, and the downright misleading. We unpack what it means to be a finance enthusiast versus an influencer, question t…