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Joint Action

David Hunter, PhD, FRACP (Rheum)

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Joint Action is a podcast hosted by David Hunter. As a consequence of isolation, those living with osteoarthritis related disability may become less fit, more depressed and anxious, more socially isolated and gain weight. It is critical at times like this that people with osteoarthritis have their burden and disability minimised and their knowledge of how to manage the disease enhanced. Join David as he interviews the world's leading experts in osteoarthritis. Professor David Hunter is a rhe ...
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Join Dr. Grigory Karmy M.D., a distinguished chronic pain management physician with over 20 years of experience, on a captivating journey through the world of pain relief in his podcast series. Delving into the latest regenerative medical treatments like PRP, stem cell injections, and prolozone therapy, alongside educational discussions on pain transmission and the latest medical innovations, Dr. Karmy shares invaluable insights and real-life stories, empowering listeners to find relief and ...
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This week's episode is in honour of Frank Beier, who recently passed away on July 18, 2025. Frank leaves behind a remarkable legacy through the impact he made in the field of osteoarthritis. In this previous episode (2021), he discussed the recent advances in osteoarthritis understanding with a particular emphasis on novel targets and epigenetics. …
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You tried injections, physiotherapy and even surgery for your sciatica, but the pain is still there. What else can you try? Find out. If you have any questions for Dr. Karmy, feel free to email us at [email protected] Follow our social media: Instagram https://www.instagram.com/karmychronicpain?igsh=cHZycXdzeGhqN2Zn Facebook https://www.fa…
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On this week's episode of Joint Action discover how ultra-processed foods may be silently contributing to osteoarthritis. Dr Gabby Joseph joins us to discuss her research research linking poor diet quality to greater knee pain, poorer physical function and thinner knee cartilage. Dr Gabby Joseph is a scientist and statistician with over 20 years of…
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Dr. Andrea Furlan is the closest thing we have to an influencer in the field of chronic pain management. She is a content creator who has a very popular YouTube channel and an author who has written several books for patients with chronic pain. She is also an educator who has developed programs for healthcare providers. Join Dr Karmy for an intervi…
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Dribbling into discovery - on this episode of Joint Action, we are joined by Dr John Drazan to learn more about how he is using basketball to inspire the next generation of scientists. Dr John Drazan is an Assistant Professor of biomedical engineering at Fairfield University where he studies the relationship between muscle structure and function to…
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Did you know your beliefs about osteoarthritis could be making your symptoms worse? In this re-aired episode from Season 5, Episode 1 of Joint Action, physiotherapist and health communication expert Dr Ben Darlow joins us to explore how common misconceptions - like “wear and tear” or “bone on bone” - can limit your activity and shape your treatment…
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Methotrexate is a well-established drug used in oncology, but could it also play a role in managing osteoarthritis? In this episode of Joint Action, Professor David Hunter is joined by Dr Anna Døssing and Professor Robin Christensen to explore the potential of methotrexate as a treatment for osteoarthritis pain. They discuss: What methotrexate is a…
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Artificial Intelligence (AI) is all over the news with headlines promising that AI will replace all human workers or possibly even take over the world. Hype aside, how will AI impact pain research? Join me for a fascinating interview with Dr. Di Ieva, a neurosurgeon and computer scientist who is using AI to study chronic pain. If you have any quest…
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Metformin is one of the world’s most prescribed drugs for type 2 diabetes - but could it also help with knee osteoarthritis? In this episode of Joint Action, Prof. David Hunter is joined by Prof. Flavia Cicuttini to unpack the results of a groundbreaking clinical trial that tested metformin as a new treatment for knee pain in people with knee osteo…
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What is it like trying to discover new medication for chronic pain? Join Dr. Karmy for an interview with Dr. Chris Bladen, CEO of Zymedyne, a Calgary biotech start-up, to learn what it takes to bring a new medication for chronic pain to patients. Learn more about Zymedyne Theapeutics here: https://zymedyne.ca/ If you have any questions for Dr. Karm…
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In this episode of Joint Action, Professor David Hunter is joined by Dr. Stephanie Mathies and Dr. Giovanni Ferreira to unpack the cost-effectiveness of osteoarthritis treatments. They discuss the results of their recent systematic review, which analysed over 100 studies to identify which guideline-recommended treatments provide the best value for …
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In this week's episode of Joint Action, Professor David Hunter is joined by Dr Sarah Kobayashi, a lecturer in anatomy and osteoarthritis researcher, to talk about the power of walking - especially for people with osteoarthritis. Sarah shares her insights into the many health benefits of walking, why it’s so important for joint health, and how to ov…
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Join Dr. Karmy for an interview with Dr. Warren Goldstein, a neurologist with extensive experience in headache management. In this episode, we will have an in-depth discussion about a new class of migraine medications that block CGRP neuropeptides. Are the risks worth the benefits? What about insurance coverage? Should you try this new class of med…
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Running often gets a bad rap when it comes to knee osteoarthritis - but is the fear justified? In this week's episode of Joint Action, Professor David Hunter speaks with physiotherapist and researcher Dr Jean-François Esculier to unpack common myths about running and joint health. They explore the latest evidence, share tips for safe running with O…
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High heels have long been associated with fashion - but what impact do they have on your joints? This week, Professor David Hunter is joined by physiotherapist and footwear researcher Dr. Kathryn Mills to unpack the biomechanics of high heels and their effect on knee health. From changes in posture and joint compression to the importance of shoe co…
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Traditionally, the Radio Frequency Ablation (RFA) procedure for chronic back pain requires approximately six injections with 2-4 inch needles followed by the insertion of heated probes to burn the nerves that supply joints of the spine called facet joints. What if you could do all that without the need for injections or heated probes? An innovative…
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Can joint replacements reduce pain, help you move more - and live longer? In this week's podcast episode, we explore the untold benefits of hip and knee replacements beyond pain relief. Dr Tim Lindsay, clinician and researcher at Imperial College London, joins us to share insights from large-scale studies that show how joint replacement can restore…
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In this episode, join Dr. Karmy as he discusses lesser-known side effects of cortisone injections. If you have any questions for Dr Karmy, feel free to email us at [email protected]. Follow our social media: Instagram https://www.instagram.com/karmychronicpain?igsh=cHZycXdzeGhqN2Zn Facebook https://www.facebook.com/profile.php?id=615502373…
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In this episode of Joint Action, Professor David Hunter is joined by Dr. Bruno da Costa, Associate Professor of Clinical Epidemiology at the University of Toronto and Senior Scientist at the University of Oxford, to unpack the evidence behind injections for osteoarthritis. Dr. da Costa shares insights from his recent systematic review and network m…
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For too long, people living with osteoarthritis have felt powerless - like there’s nothing they can do to influence change. But that couldn’t be further from the truth. In this powerful episode, Prof. David Hunter is joined by Louise Hardy, Director of Policy and Advocacy at Arthritis Australia, to explore how individuals can use their voice to dri…
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In this episode, Dr. Karmy will review everything known so far about the newest and first-in-class non-addictive pain medication, Journavx. Follow our social media: Instagram https://www.instagram.com/karmychronicpain?igsh=cHZycXdzeGhqN2Zn Facebook https://www.facebook.com/profile.php?id=61550237320641&mibextid=dGKdO6 Send us a text with your thoug…
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MRIs are increasingly used to detect early signs of osteoarthritis - but are they truly beneficial for most people? On this week's episode, we examine the role of MRI scans in diagnosing knee osteoarthritis, particularly in its early stages. Joined by leading experts Dr. Alison Chang, a professor of Physical Therapy at Northwestern University, and …
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What if you could know your risk of developing osteoarthritis years before symptoms appear? In this episode, we explore whether a blood test could provide those answers. Joining us on this week's episode is Dr. Virginia Kraus, a leading rheumatologist and researcher, to discuss her study that identified osteoarthritis risk up to 10 years in advance…
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This episode describes Dr. Karmy's approach to patients with fibromyalgia. He delves into what are the treatments he finds the most helpful and the pros and cons of each approach. If you have any questions for Dr Karmy, feel free to email us at [email protected]. Follow our social media: Instagram https://www.instagram.com/karmychronicpain…
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Menopause is often referred to as "the change" and remains a complex and sensitive topic for many. Despite being historically under-discussed, it's crucial to address because of its profound impact on musculoskeletal health. Women are two to three times more likely than men to develop osteoarthritis, particularly around menopause. Changes in hormon…
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In this special episode of Joint Action, host Professor David Hunter brings together the most valuable insights from over 100 episodes, creating a practical guide to understanding and managing osteoarthritis. By summarising years of expert advice, groundbreaking research, and real-world strategies, this episode makes it easy to access the latest in…
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Most of us have experience with earaches, either in our children or sometimes through personal experience. Although the pain is severe, it does resolve in a few days. What if the pain never went away? Join Dr Karmy for an interview with a clinic patient who has a very unusual chronic pain condition. In this interview, we discuss how our patient fou…
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Join us for a unique and inspiring episode of the Joint Action podcast, where we step into a stylised clinical encounter between Professor Shannon Mihalko, acting as the clinician, and Tom Buttel, the patient. Together, they delve into the realities of living with osteoarthritis, sharing powerful insights into overcoming challenges, setting meaning…
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Welcome to Season 6 of the Joint Action Podcast and the first episode of 2025! We're kicking off with a crucial topic in advancing osteoarthritis treatment: understanding clinical trials. Clinical trials are vital for developing new treatments for osteoarthritis, yet many people are mystified by the process. Why participate? What are the benefits? …
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In our final episode for 2024, we answer your burning questions about osteoarthritis! Host Professor David Hunter dives deep into a variety of listener-submitted topics, including: The evidence (or lack thereof) behind treatments like pentosan polysulfate and Epiitalis Whether weightlifting and high-impact activities increase the risk of osteoarthr…
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In the second part of the interview with Dr.Howard Jacobs, one of the fathers of pain management in Ontario, we discuss how the medical discipline of Chronic Pain developed in the last 20 years and the challenges facing it in the future. Listen to Episode 10-Part 1 of this interview to discover how Dr. Howard Jacobs revolutionized chronic pain mana…
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This week on the Joint Action podcast, we’re joined by Professor Henning Bliddal, a leading researcher and Director at the Parker Institute in Denmark. Henning Bliddal has spent his career helping people with osteoarthritis live better lives. In this episode, we talk about a breakthrough study using a medication called Semaglutide. This drug, origi…
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Join Dr. Karmy for an in-depth interview with Dr. Jennifer Woodell-May who was instrumental in the development of the newest treatment for osteoarthritis. In this episode, Dr. Woodell-May answers the following questions: 1. How are new autologous and regenerative treatments created? 2. What are some of the obstacles to creating new autologous, cell…
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Ever wonder if the weather really impacts your joint pain? If you've ever felt like cold, damp days make your knees ache more, you're not alone - many people with osteoarthritis believe there's a strong link between weather and joint pain. But is there really a connection? In this episode of the Joint Action Podcast, we're joined by Professor Manue…
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Join Dr. Karmy for an interview with Acorn Biolabs CEO, Dr. Taylor, where they discuss the unique approach his company is taking to stem cell treatments. The wide ranging discussion will also cover his vision for the future of his company and how it fits into the broader field of regenerative medicine. Acorn Biolabs: Acorn Biolabs - Personalized Re…
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This week, we dive into the pressing need to shift osteoarthritis management away from costly, invasive procedures like knee replacements toward more accessible, non-surgical treatments. Professor Ilana Ackerman from Monash University joins us to discuss why lifestyle changes - exercise, diet, and education - should be the first line of care, backe…
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There was a time in Ontario when chronic pain patients who didn’t respond to physiotherapy or surgery were often given only basic advice to exercise or referred to a psychologist or psychiatrist to ensure they weren’t suffering from depression. But then, Dr. Peter Rothbart changed everything by founding the first community-based chronic pain clinic…
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In this week's episode of Joint Action, we explore how the built environment - where you live, work, and move - impacts your likelihood of staying physically active while living with osteoarthritis. Our guest, Dr. Sarah Gebauer, a family physician and translational epidemiologist, discusses the concept of "walkability" and how access to sidewalks, …
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In this week's episode of Joint Action, we dive deep into the question: why do women experience more osteoarthritis than men? Host Professor David Hunter is joined by experts Assistant Professor Tristan Maerz and Assistant Professor Dieuwke Schiphof to explore the biological and gender-based differences that contribute to osteoarthritis prevalence,…
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The Osteoarthritis Prevention Study run by University of Sydney researchers is currently recruiting woman aged 50 years or older with a BMI of 30 or more. The study is perfect for women who would like to take control of their health and participate in diet and exercise classes or health education classes in a safe and supportive environment. To lea…
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In this episode, Dr. Karmy dives into the facts and misconceptions surrounding cortisone injections. Often misunderstood, these powerful anti-inflammatory treatments can offer significant relief for joint pain, tendon issues, and nerve inflammation. Join Dr Karmy as he explores when cortisone is most effective, its potential risks, and why it may n…
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In this week's episode, we explore the quest for a therapy that not only alleviates symptoms of osteoarthritis but also addresses the underlying disease process. Host Professor David Hunter is joined by Chris Knight and Dr Sandeep Basnet from Formation Bio to discuss the complexities and breakthroughs in developing disease-modifying osteoarthritis …
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Botox is best known as a cosmetic treatment, however in addition to cosmetic uses it has a wide range of medical applications. In this episode, Dr Karmy explores the role of Botox therapeutic injections in managing chronic migraines—a condition that impacts millions worldwide and is often resistant to traditional medications. Join Dr. Karmy as he b…
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This week on Joint Action, we explore the potential of natural ingredients in relieving knee osteoarthritis pain. We start with a short introduction to the ATLAS study, a clinical trial by Professor David Hunter and a team of researchers at The University of Sydney. The ATLAS study is testing a groundbreaking supplement combining curcumin, boswelli…
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In this episode, Dr Karmy explores the world of radiofrequency ablation—a novel, OHIP-covered treatment for chronic back pain. He goes over the differences between radiofrequency ablation, pulsed radiofrequency, and cooled radiofrequency ablation, uncovering how each technique works and when they should be considered viable treatment options. Join …
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In this episode of the Joint Action podcast, we explore how injuries to the ACL (anterior cruciate ligament) in the knee can lead to osteoarthritis, especially in young people aged 15-25. Did you know that up to 20% of people who develop knee osteoarthritis do so because of a past injury? ACL injuries are a major culprit, and their impact can be li…
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In this episode, Dr Karmy is joined by Dr. James Henry, a pioneering expert in the field, where they dive deep into the neurobiology of pain. Trained at McGill University and with a distinguished career spanning Western University and McMaster's Michael De Groote Pain Center, Dr. Henry brings a wealth of knowledge on the role of neuropeptides in ch…
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On this week's episode of the Joint Action podcast, we dive into a critical aspect of osteoarthritis care: pain management. Dr Stefan Ivanavicius and Dr Sarah Kennedy join us to unravel why pain remains an unmet need in osteoarthritis. They shed light on the complexity of pain, influenced by biological, psychological, and social factors. We explore…
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In this episode, we dive into the often overlooked world of younger adults living with osteoarthritis. Associate Professor Anthony Perruccio joins us to explore why people develop osteoarthritis and the unique challenges faced by younger individuals with the disease. We discuss key risk factors such as age, sex, weight, genetics, prior joint injuri…
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In this episode, Dr Karmy will take an in-depth look at the newest treatment for osteoarthritis—the nSTRIDE Autologous Protein Solution (APS) kit. Like Platelet Rich Plasma (PRP), this treatment is made from the patient's own blood. How does it compare to PRP? Is it worth trying? Dr. Karmy will not only explain the science behind nSTRIDE from exist…
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