Conversations with founders, operators and investors who are building the future. Listen to find the stories, ideas, tactics & investments behind the products that will define the future of technology. https://startupproject.substack.com/
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Nataraj Podcasts
Nodycast is a lively podcast discussing the theory, techniques and latest innovations in nonlinear dynamics, and its applications to systems of all kinds. This includes almost everything under the sun such as mechanical, structural, electrical, chemical, thermo-fluid, ecological, economic, epidemiological, biological and chemical systems. It is hosted by Dr. 'Nat' C. Nataraj, Moritz Professor at Villanova University and Senior Editor for Nonlinear Dynamics, a Springer-Nature journal.
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On The Bioinformatics CRO Podcast, we sit down with scientists to discuss interesting topics across biomedical research and to explore what made them who they are today.
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Chitheads is a smorgasbord of contemplative education. Each episode is like a mini masterclass, exploring the diverse landscapes of spiritual practice, philosophy, and the transformative power of embodied knowledge. Each episode is crafted with the curious and open heart in mind, aiming to illuminate the path of self-inquiry and empowerment for yoga teachers, scholar-practitioners, meditators and other spiritual seekers and contemplative folks from around the world. From the profound teachin ...
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This is Oh Ship, the show where experts and leaders look back at their biggest moments of failure just so you can avoid making them. And there is no one better to squeeze the naked truth out of our charismatic guests than your host, Chameleon Collective Founding Partner, Freddie Laker.
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Nataraj Pagadala - molecular glues for targeted protein degradation
31:01
31:01
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31:01Nataraj Pagadala, founder, president, and CEO of LigronBio, discusses his company's goal of using molecular glues to target traditionally undruggable proteins as a route to new therapies for neurodegenerative diseases. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic res…
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How AI Is Unlocking Materials We’ve Never Been Able to Build | Radical AI
38:21
38:21
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38:21Discover how Radical AI is revolutionizing material science using self-driving labs. About the episode: Nataraj hosts Joseph Krause, CEO of Radical AI, to explore how they're speeding up material R&D by combining AI, engineering, and robotics. Joseph shares his journey from material science to venture capital, highlighting Radical AI's mission to c…
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Chris Yohn - bridging computational biology and the wet lab
38:42
38:42
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38:42Chris Yohn, leader of CompBio Bridge, discusses his current experience with computational biology contracting and consulting, what companies are doing with computational biology right now, and how to most effectively bridge the gap between data science and the wet lab. The Bioinformatics CRO is a fully distributed contract research company that ser…
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Phillip Meade - building high-performance culture
44:01
44:01
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44:01Dr. Phillip Meade, a leadership and culture advisor at Gallaher Edge, discusses his experience evaluating organizational culture and how to diagnose culture problems and build lasting habits for high-performance organizations. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of acad…
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Why the Humanities Are Dying and the Revival of Holistic Education with Athena Potari
1:18:15
1:18:15
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1:18:15In this timely and energizing conversation, Jacob speaks with philosopher and Hellenic wisdom teacher Athena Potari about the crisis and rebirth of the humanities. Drawing on her work with the Galileo Commission and her training in ancient Greek philosophy, Athena describes how modern academia has reduced the human being to brain chemistry and data…
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Sophia George - hereditary breast and ovarian cancer
42:00
42:00
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42:00Sophia George, professor in the Division of Gynecological Oncology at the University of Miami Miller School of Medicine, discusses her research at the Sylvester Comprehensive Cancer Center investigating the genetics and biology of hereditary breast and ovarian cancer and working at the intersection of genomics, health equity, and cancer. The Bioinf…
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Manifestation Isn't Magic with Jacob Kyle
1:07:19
1:07:19
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1:07:19In the highest view, the fruit of practice is not the attainment of something new but the effortless recognition of what has always been — ānanda, the bliss inherent in awareness itself. The Anupāya — the “methodless method” — is not about doing but about relaxing into this truth. In this final talk, we’ll explore how genuine manifestation flows no…
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How Decagon Built Human-Level AI Support: Ashwin Sreenivas on customer obsession, early traction, enterprise complexity, and the AI concierge future
49:01
49:01
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49:01Unlock the secrets to Decagon AI's $1.5 billion valuation and AI-powered customer support. Ashwin Sreenivas is the co-founder of Decagon AI, a company revolutionizing enterprise customer support with AI agents. Founded in 2023, Decagon has rapidly grown to a $1.5 billion valuation, automating support workflows for brands like Duolingo and Notion. A…
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Christiaan Engstrom - building life sciences partnering networks
32:39
32:39
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32:39Christiaan Engstrom, founder and CEO of BLPN, discusses his experience building a space for authentic, non-transactional business networking in the life sciences. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechnology companies, with a focus on ge…
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From Forbes to Founder: Alex Konrad on new media, creator economy, AI tools for journalists, Midas List secrets, and why traditional media is losing to independent voices
46:28
46:28
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46:28Discover the evolving roles of traditional vs. new media in tech and gain insights into effective content creation strategies. About the episode: In this episode, Nataraj hosts Alex Konrad, founder and editor of Upstart Media, to explore the shifting dynamics of tech media. Alex shares his experiences at Forbes, defines the roles of traditional and…
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Joanne Hackett - revolutionising the future of healthcare
47:15
47:15
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47:15Dr. Joanne Hackett, VP of Health Systems Services at IQVIA and Chair of the Board at eLife, discusses her hopes for the future of healthcare. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechnology companies, with a focus on genomics. https://www.b…
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AI Hype, Future Trends & Research Trends with Best Selling Author of The Master Algorithm Pedro Domingos
1:21:38
1:21:38
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1:21:38This week we are republishing one of our favourite conversations that didn't get much visibility when it first came out. About the episode: Nataraj hosts Pedro Domingos, a distinguished figure in AI and machine learning, to discuss the current state of AI, hype cycles, and future trends. Pedro shares insights from his early career, his widely-read …
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The Invisible Layer Powering the AI Infrastructure | Co-Founder and CEO of Momento | Khawaja Shams
39:26
39:26
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39:26We are republishing one of our favorite episode with the co-founder of Momento this week, we will be publishing a brand new episode next week. Discover how a NASA engineer leveraged AWS to build a serverless caching solution. About the episode: Join Nataraj as he speaks with Khawaja Shams, co-founder and CEO of Momento, a serverless caching solutio…
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David Scieszka - senolytic vaccines to extend healthspan
38:30
38:30
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38:30David Scieszka, founder and CEO of Vertical Longevity Pharmaceuticals, tells us about VeLo's pioneering senolytic vaccine approach to clearing senescent cells and his quest for longer, healthier lives for everyone. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researc…
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Offline AI, personal AI assistants, edge computing revolution, compression of neural networks, privacy, compute efficiency, AI infrastructure startups | David Stout, Founder of webAI
1:05:25
1:05:25
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1:05:25Discover how webAI is revolutionizing AI by enabling powerful models to run directly on devices. About the episode: Nataraj chats with David Stout, founder of webAI, about bringing AI infrastructure to edge devices. David shares his journey from a Michigan farm to pioneering techniques for compressing AI models onto phones, laptops, and even airpla…
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Everything is the Goddess with Nataraj Chaitanya
1:06:42
1:06:42
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1:06:42In this episode, Jacob Kyle sits down with his longtime friend and collaborator Nataraj Chaitanya, whose early creative influence helped shape the founding vision of Embodied Philosophy and even inspired the name CHITHEADS. Ten years after those first late-night conversations about yoga, consciousness, and modern spirituality, Jacob and Nataraj reu…
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Caspar Barnes - blockchain infrastructure for biobanking
43:35
43:35
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Manos Metzakopian - CellCodex and AI-ready datasets
25:01
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25:01Manos Metzakopian, co-founder and CEO of CellCodex, joins us to discuss CellCodex's mission to provide high-quality, scalable cellular perturbation data, ready to train advanced AI models for biology. Our host, Grant Belgard, is also a co-founder and the CTO of CellCodex. The Bioinformatics CRO is a fully distributed contract research company that …
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Fixing Broken Meetings, Managing Calendars with AI, and Redesigning the Future of Work | Matt Martin CEO & Co-Founder Clockwise
49:00
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49:00In this episode, Nataraj welcomes Matt Martin, CEO of Clockwise, to explore the science of smart scheduling. Discover how Clockwise uses AI to optimize calendars, reduce meeting overload, and create more focused work time. Matt shares insights on balancing collaboration with individual productivity, the impact of remote work on meeting culture, and…
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Dr. Eva-Maria Hempe, who leads NVIDIA's healthcare and life sciences business across Europe, the Middle East, and Africa, joins us to discuss her work at NVIDIA, the gaps that AI can fill in healthcare research, and the future of drug discovery. The Bioinformatics CRO is a fully distributed contract research company that serves the computational bi…
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The Future of Enterprise AI: $100M ARR, Agents, Company Building, and Scaling Unicorns | Arvind Jain (Co-founder of Glean, Rubrik, ex-Google)
54:02
54:02
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54:02Discover how Glean AI is transforming enterprise productivity with AI-powered search and intelligent agents. About the episode: Join Nataraj as he explores the evolution of enterprise AI with Arvind Jain, CEO of Glean. From its roots as an AI-powered search solution, Glean has transformed into a comprehensive AI agent platform, helping companies li…
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Jeff Bizzaro - open source, open access bioinformatics
22:23
22:23
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22:23Jeff Bizzaro, founder and long-time president of bioinformatics.org, discusses the importance of open source tools and open access in the life sciences. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechnology companies, with a focus on genomics. ht…
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APIs as Graphs not Endpoints, building a company on open source foundations, why VPs of Engineering face impossible trade-offs | Apollo GraphQL CEO Matt DeBergalis
50:42
50:42
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50:42### About the episode: Join Nataraj as he interviews Matt DeBergalis, CEO of Apollo GraphQL, about the evolution of GraphQL from an open-source project to a product company. Matt shares insights on building and scaling APIs, the challenges of transitioning open-source tech into a viable business, and how AI is reshaping API development. Discover ho…
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Afshin Beheshti, director of the University of Pittsburgh's new Center for Space Biomedicine, discusses the importance of space biomedicine to understanding human health both in space and on earth. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechn…
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How to be an AI first company, Enterprise AI adoption, Future of Developers, Cost of AI, Unlocking value from Enterprise Data with AI & more with Ben Kus | CTO of Box
55:25
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55:25In this episode of Startup Project, Nataraj interviews Ben Kus, CTO of Box, about the critical role of unstructured data in the AI revolution. They discuss the cost structures of adopting and building with AI, and how AI is transforming enterprise businesses. Ben shares Box's unique perspective, managing over an exabyte of data for 120,000 enterpri…
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Automating Startup Formation, Scaling Fund Products, Applying AI Across Venture Tools | AngelList CTO Goutham Buchi
49:25
49:25
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49:25About the Episode: This episode dives into AngelList's core products and how they strengthen the startup ecosystem. Goutham explains how AngelList sits at the center of founders, GPs, and LPs, providing tools and infrastructure to fuel innovation. He discusses the impact of AI on AngelList's operations, from streamlining fund deployment to providin…
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Kenny Workman - modern data infrastructure for biosciences
54:02
54:02
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54:02Kenny Workman, co-founder and CTO of LatchBio, discusses his experience building a cloud platform for modern biology and how Latch has grown since our 2022 episode with his co-founder Alfredo Andere. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotec…
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Don Alexander, founder and president of GeneCoda, discusses the current climate in hiring for life sciences, trends in remote and hybrid work, and the impact of AI on expectations for candidates. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechnol…
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How Publishers are Navigating Advertising, AI's Impact on Search Traffic, Biased Incentives of Ad Industry, Future of Publishing | Jared Siegal Founder of Aditude Inc | #104
49:24
49:24
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49:24About the episode: Join Nataraj as he explores the world of online advertising with Jared Siegal, founder and CEO of Aditude. Discover how programmatic advertising empowers publishers to scale their revenue and the evolving landscape of online monetization. They discuss the roles of different players in the ad industry, the impact of AI on search t…
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Elizabeth Ruzzo - endogenomics for inclusive scientific discovery
40:19
40:19
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40:19Dr. Elizabeth Ruzzo, founder and CEO of Adyn, discusses precision medicine for personalized birth control and her commitment to using pioneering endogenomics to make scientific discovery more inclusive. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and bio…
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AI Startup Cleaning Up a $1.6 Trillion Crisis, Building a Hardware + AI Startup, Scaling Edge AI, Digitize Waster & Reduce Landfill | Ambarish Mitra Co-Founder of Greyparrot AI | #103
40:10
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40:10Join Nataraj as he interviews Rish, the co-founder and CEO of Greyparrot, a company leveraging AI to revolutionize the recycling industry. Rish shares his journey from augmented reality to AI-powered waste management, detailing the challenges and opportunities in this space. Discover how Greyparrot's innovative technology brings transparency and ef…
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This episode features a stimulating discussion between Prof. Nataraj (host) and Prof. Steven Shaw. Prof. Shaw is a Professor at Florida Tech in Melbourne, Florida, and is a prolific and noted scholar with many publications in nonlinear dynamics. His work ranges over a number of diverse areas including fundamental physics, modeling, and design of re…
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Max Marchione - Superpower and affordable concierge medicine
41:46
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41:46Max Marchione, Co-Founder of Superpower, discusses his experience founding a health tech company, making concierge medicine accessible to all, and the future of healthcare. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechnology companies, with a f…
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Spiritual Bypassing, Non-Dualism Explained, and the 4th State of Consciousness with Jacob Kyle
42:22
42:22
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42:22In this episode, Jacob Kyle offers a curated selection of teachings from Sādhana School, Embodied Philosophy’s year-long curriculum of contemplative study and practice. The episode weaves together reflections on states of consciousness, metaphysics, emotional transformation, and the pitfalls of spiritual bypassing, drawing deeply from Indian philos…
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How Statsig Founder Vijaye Raji Built a $1.1B Product Development Platform | CEO & Co-Founder of Statsig | Startup Project #102
51:34
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51:34Join Nataraj as he sits down with Vijaye Raji, founder and CEO of Statsig, a platform revolutionizing product development with data-driven decision-making. Formerly a VP at Facebook and head of Facebook Seattle, Vijaye shares his journey from big tech to startup founder. About the Episode: This conversation explores Vijaye's transition from leading…
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Wolfgang Brysch - inflammation, cellular metabolism, and ageing
31:04
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31:04Wolfgang Brysch, Co-Founder and CSO of MetrioPharm and iüLabs, discusses longevity, inflammation, and his dual path of research into natural and pharmaceutical remedies. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotechnology companies, with a focu…
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How Chronosphere Solved Observability in Containerized Environments to Build $1.6B Company | Uber spin-out, 5x Cheap & Impact of AI in Observability | CEO Martin Mao | Startup Project #101
50:47
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50:47Martin Mao is the co-founder and CEO of Chronosphere, an observability platform built for the modern containerized world. Prior to Chronosphere, Martin led the observability team at Uber, tackling the unique challenges of large-scale distributed systems. With a background as a technical lead at AWS, Martin brings unique experience in building scala…
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Scott Fahrenkrug - seaweed genetics and the agricultural future
45:50
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45:50Scott Fahrenkrug, founder of Forjazul, discusses his path toward seaweed research, the importance of genetic knowledge for agriculture, and how Kappaphycus alvarezii can help move us into the future. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of academic researchers and biotec…
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The Unfiltered Playbook to Make Early‑Stage Startups Get Media Traction & Demystifying Public Relations for Tech Founders | Emilie Gerber Founder of Six Eastern PR | Startup Project #100
49:36
49:36
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49:36Join host Nataraj as he speaks with Emilie Gerber, founder and principal of SixEastern, a PR firm specializing in startups and tech companies. Emilie shares her expertise on crafting effective PR strategies for early-stage startups and navigating the evolving media landscape. About the Episode: This episode demystifies the world of PR for tech foun…
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Award-Winning Industrial Designer on How to Design Great Hardware Products at Scale? | Todd Bracher Founder of Betterlab | Startup Project #99
47:12
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47:12Join host Nataraj as he sits down with Todd Bracher, founder of BetterLab, an industrial design firm partnering with scientists and innovators to create game-changing products. Previously Executive Creative Director and Design Partner at Human Scale, Todd has also collaborated with iconic brands like Issey Miyake, Herman Miller, and 3M. A two-time …
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The Power of Poetry in Medieval Kashmir with James D. Reich
1:24:19
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1:24:19In this conversation, Jacob Kyle and James D. Reich discuss the concept of Rasa in Indian aesthetics and literary theory. They explore the idea that poetry and art can evoke a specific emotional experience in the audience, known as Rasa. They delve into the theories of Anandavardhana and Abhinavagupta, who developed the concept of Rasa and its asso…
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Warp Dev The AI Terminal Changing Software Development | Zach Lloyd CEO & Co-Founder of Warp Dev | Startup Project #98
50:51
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50:51Join host Nataraj as he sits down with Zach Lloyd, the founder and CEO of Warp, a company developing an intelligent terminal aimed at modernizing the command line experience for developers. Zach, a former principal engineer at Google, having worked on Google Sheets and Docs, and co-founder and CTO of Selfmade, shares his insights on the future of s…
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How to Build a Scalable Venture Community | Jennifer Jeronimo CEO of Gaingels Inc| Startup Project #97
32:03
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32:03Join Nataraj on Startup Project as he interviews Jennifer Jeronimo, CEO of Gaingels, a venture capital syndicate that has deployed over $900 million into 2,500 startups. About the Episode: Jennifer shares Gaingels' unique journey from an investment club focused on LGBTQ+ founders to one of the largest venture capital syndicates globally, with a div…
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Startup Mistakes to Avoid: Overvaluation, Fundraising, AI & SaaS Pricing | Vanessa Larco Partner at NEA | Startup Project #96
44:48
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44:48Join host Nataraj on Startup Project as he sits down with Vanessa Larco, Partner at NEA, to discuss the transformative impact of AI on startups and venture capital. About the Episode: This episode delves into the evolving landscape of tech investing, exploring how AI is reshaping business models, pricing strategies, and the future of work. Vanessa,…
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Deep Tech's Golden Age: Investing in Robotics, AI, and Quantum Computing | Startup Project #95
49:23
49:23
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49:23Join host Nataraj as he sits down with Karthee Madasamy, the Managing Director of MFA Partners, to discuss his journey from chip designer to venture capitalist in the world of deep tech. About the Episode: This episode explores Karthee's transition from a technical background in semiconductors and wireless communication to a successful career in ve…
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Ritual, Reality & the Sri Yantra with Kavitha Chinnaiyan
1:18:56
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1:18:56In this episode, Jacob Kyle and Kavitha Chinnaiyan delve into the intricate world of the Sri Chakra and Sri Yantra, exploring their significance in Tantric practices. Kavitha shares insights from her latest book, discussing the complexities of the Sri Yantra, its historical context, and the importance of ritual in spiritual practice. They also touc…
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Secondary Markets Explained: How EquityZen Provides Liquidity for Pre-IPO Shares | Startup Project Podcast #94
50:32
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50:32Join Nataraj on Startup Project as he talks to Aatish, CEO and founder of EquityZen, a secondary market for private equities. They discuss the evolution of secondary markets, EquityZen's business model, the value proposition of secondary equity platforms, investor strategies, and the nuances of investing in secondary shares. They'll also delve into…
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Seattle's Ambition to Become the Next Silicon Valley | Aviel Ginsberg | Startup Project #93
47:15
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47:15Join host Nataraj as he sits down with Aviel Ginsberg, the founder of Simply Measured (acquired by Sprout Social), managing director at Amazon's Alexa Accelerator, general partner at Founders Co-op, and now co-founder of Foundations, a shared workspace and accelerator designed to bolster Seattle's VC ecosystem. About the Episode: This episode explo…
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Revolutionizing Workflows with AI Agents | Jacob Bank | relay app | Startup Project
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44:54Join host Nataraj as he sits down with Jacob Bank, founder and CEO of Relay.app, a platform building AI agents to revolutionize how we work. **About the Episode:**This conversation explores the evolution of AI agents and how Relay is solving customer problems by automating cross-tool workflows. Jacob, a former product lead at Google (Gmail, G Suite…
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Building a Billion-Dollar Portfolio: David Blumberg's Investment Strategies | Startup Project #91
56:55
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56:55Join host Nataraj on the Startup Project podcast as he sits down with David Blumberg, a seasoned investor with over three decades of experience in early-stage tech companies. From his early days at T. Rowe Price to founding Bloomberg Capital, David shares his unique journey and insights into the world of venture capital. About the Episode: This epi…
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