IDEA Collider explores how asymmetric learning drives bold innovation in the pharmaceutical and life sciences industries. Hosted by Mike Rea, CEO of IDEA Pharma & Head of Strategy and Thought Leadership at SAI MedPartners, the podcast features conversations with top thinkers, scientists, and strategists who challenge the status quo to spark real progress in drug development, biotech, and healthcare. Each episode dives into how organizations can make smarter decisions earlier, reimagine R&D, ...
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IDEA Pharma Podcasts
Free Minds for a Free Society
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The Business of Biotech is the pod dedicated to leaders of emerging biopharma firms. SUBSCRIBE to our new newsletter at www.bioprocessonline.com/bob. We bring you insight into organizational, finance and funding, HR, clinical, manufacturing, regulatory, and commercial challenges you’ll face as you navigate your company from an idea to success in the clinic and beyond. Each episode features guest commentary and best practices from accomplished founders and biopharma industry luminaries. The B ...
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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance ...
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Driving inspiration, conversation and diversity in advertising
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CURIOUS ABOUT HOW TO MAKE THAT CAREER CHANGE? BURNED OUT ON YOUR LAST JOB & CURIOUS ABOUT DIFFERENT CAREERS? OR MAYBE YOU HAVE NO IDEA HOW TO GET INTO A PARTICULAR FIELD... LOOK. NO. FURTHER. Angela Stephens has over 30 years of experience as a Retained Recruiter: https://www.linkedin.com/in/angelaastephens/ In fact, she started her 30 year Executive Search Firm business with only $3,000 and grew it into one of the leading executive search firms in the country specializing in the pharma, bio ...
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Dr. Christian Rommel on Oncology Innovations and Modern Drug Development at Bayer
50:14
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50:14In this episode of Idea Collider, host Mike Rea interviews Dr. Christian Rommel from Bayer. Dr. Rommel discusses his journey in molecular oncology from the Max Planck Institute, through roles at Roche, to overseeing global R&D at Bayer. He shares insights on turning scientific discovery into novel medicines, collaboration between scientists and com…
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The Hidden Traps of “Healthy” Eating (Biohacking Daily Nutrition) : 1324
1:00:01
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1:00:01What if the foods you think are healthy are actually disrupting your biology? From sugar marketed as a performance tool to “whole grains” that drive cravings, this episode uncovers how hidden traps in modern nutrition can hijack your brain, wreck your metabolism, and accelerate aging. You’ll learn how to rethink daily eating so it fuels energy, res…
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Sulforaphane, Curcumin, and NEW GLP-1 Drugs (Biohacking for Longevity) : 1323
1:02:41
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1:02:41Most people think broccoli is a superfood, but the reality is more nuanced. In this episode of The Human Upgrade, Host Dave Asprey explores the good and bad of broccoli—why adult broccoli can block thyroid function and cause gut issues, while broccoli seeds deliver sulforaphane, the powerful compound that activates all three of your body’s detox pa…
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Mast Cells Explained: Biohacking Inflammation, Allergies, and Brain Fog : 1322
1:29:29
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1:29:29Millions of people are living with unexplained symptoms like allergies, brain fog, anxiety, and chronic fatigue without realizing the hidden cause: mast cells gone rogue. In this episode of The Human Upgrade, Host Dave Asprey sits down with leading functional medicine physician Dr. Tania Dempsey to uncover how Mast Cell Activation Syndrome (MCAS) d…
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Improving Cardiovascular Outcomes With Immediate Therapeutics' Atul Deshpande, Ph.D.
1:04:36
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1:04:36We love to hear from our listeners. Send us a message. On this week's episode, Atul Deshpande, Ph.D., CEO at Immediate Therapeutics, talks about partnering with American cities to conduct clinical trials during ambulance rides to the hospital, with the goal of preserving heart function and reducing mortality related to acute cardiovascular events, …
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What Is Uric Acid and How Does It Predict Your Longevity : 1321
1:09:44
1:09:44
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1:09:44Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer’s, and even accelerated aging—and how you can hack it to unlo…
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Hacking Dopamine Naturally: Pain, Focus, and Performance : 1320
1:15:10
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1:15:10Your dopamine system is being hijacked every day, and the way to reclaim it might surprise you. This episode reveals how pain, pleasure, and addiction are wired in your brain, and how to use that knowledge for real brain optimization, resilience, and longevity. You’ll discover why your dopamine levels control motivation, focus, mood, and even cravi…
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You Have A 25% Chance to Lose All Your Memory (Longevity Secrets) : 1319
1:46:41
1:46:41
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1:46:41Alzheimer’s is not inevitable—and it may even be optional. In this groundbreaking episode, you’ll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBP…
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Building A Biotech Incubator And Accelerator With Swiss Rockets Founder And CEO Vladimir Cmiljanovic, Ph.D.
52:07
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52:07We love to hear from our listeners. Send us a message. On this week's episode, ex-handballer Vladimir Cmiljanovic, Ph.D., Founder and CEO at Swiss Rockets, talks about co-discovering bimiralisib with his sister Natasa Cmiljanovic, Ph.D. (and COO at Swiss Rockets), losing his company to a hostile takeover, buying the company back, and building out S…
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The Hormone War Dividing Female and Male Longevity : 1318
53:48
53:48
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53:48Your hormones may be waging a hidden war that determines how long you live and how well you perform. This episode reveals how male and female biology diverge—and what those differences mean for your longevity, metabolism, and brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Revi…
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The 10-Second At-Home Walk Test for Longevity (Easy Biohack) : 1317
1:07:06
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1:07:06Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You’ll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pe…
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PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316
1:08:04
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1:08:04Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade …
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Biotech Product Partnership with Coya Therapeutics' Arun Swaminathan, Ph.D. and Dr. Reddy's Milan Kalawadia
52:37
52:37
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52:37We love to hear from our listeners. Send us a message. On this week's episode, Milan Kalawadia, CEO, North America, Dr. Reddy's Laboratories, and Arun Swaminathan, Ph.D., CEO, Coya Therapeutics discuss their unique partnership to develop COYA 302, a novel dual-mechanism immunotherapy for the treatment of ALS. The partnership pairs Coya's scientific…
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Still Fasting in 2025? Here’s How to Make It Work Better : 1315
59:50
59:50
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59:50How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mito…
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Why the Lack of Beauty is Destroying Society
14:38
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14:38“We have technology, convenience, security, and a measure of prosperity, but where is the beauty? Where is the beauty that we know we cannot really live without?” John-Mark Miravalle, Beauty: What it is and Why it Matters In 2009 the late English philosopher Roger Scruton warned that “Beauty is vanishing from our world”, and that […] The post Why t…
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How to Make Life-Changing Decisions Without Fear – Joe Hudson : 1314
52:09
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52:09How do you make tough decisions? How do you make them without fear or lying? This episode shows you how unresolved emotions disrupt decision-making, relationships, and functioning in peak brain performance. You’ll learn tips to rewire your nervous system for decision making, optimizing emotional intelligence, and regulating your body for high-level…
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The New Poisons Lurking Around You – Save Your Longevity : 1313
58:58
58:58
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58:58Toxins you cannot see are damaging your health, wrecking your metabolism, and quietly accelerating aging. This episode reveals how to detect the new poisons lurking in your home, how they sabotage mitochondria and brain optimization, and the biohacking fixes that restore longevity, energy, and human performance. You’ll learn actionable strategies y…
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How To Hire And Build A Winning Executive Team With Occam Global's Bill Holodnak
58:11
58:11
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58:11We love to hear from our listeners. Send us a message. On this week's episode, Bill Holodnak, Cofounder and CEO of Occam Global, a life sciences executive recruitment firm (and occasional investor), shares insights from his decades of experience pairing executives with drug development companies, and talks about the psychology of successful biotech…
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Jim Kwik: What I Take to Biohack Brain Speed and Focus : 1312
59:39
59:39
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59:39Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization protocols Jim Kwik uses daily, plus the biohacking routines that rebuilt his cognition after traumatic brain injury. Watch this episode on YouTube for the …
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Why I Inject a “Female Hormone” 3x a Week (Nootropic Hacking) : 1311
1:38:53
1:38:53
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1:38:53What if the most powerful upgrades for brain energy, metabolism, and drive aren’t in mainstream medicine, but in rare peptides and misunderstood hormones? In this episode, you’ll discover the cutting-edge compounds, nootropics, and hormonal strategies that elite biohackers are using right now to optimize every part of their biology. Watch this epis…
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Top 5 Dopamine Boosting Biohacks for Superhuman Energy : 1310
1:04:20
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1:04:20Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, and biohacking protocols that top performers are using to supercharge human performance, brain optimization, and long-term resilience. Watch this epis…
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The Generalist Biotech CEO With Seekyo's Oury Chetboun
52:03
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52:03We love to hear from our listeners. Send us a message. On this week's episode, Oury Chetboun, co-founder and CEO of Seekyo, a French biotech, talks about the range of experiences that prepared him to lead a company focused on developing innovative solid tumor treatments that target functional proteins in the tumor micro-environment. Chetboun talks …
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Protein vs. Plants: The 50g-a-Meal Biohacking Rule : 1309
47:04
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47:04Getting 50 grams of protein per meal may be the single most underrated biohacking protein strategy for muscle growth, metabolism, and longevity. In this episode, you’ll discover why animal protein vs vegan is not a fair match biologically, how hitting the leucine threshold activates mTOR for longevity, and why muscle is the most overlooked organ of…
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The Air Force Uses This Mind-Bending Sound Biohack — Try It Yourself! : 1308
54:05
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54:05This episode reveals how military-grade sound frequencies can rapidly shift your mental state, enhance neuroplasticity, and accelerate brain optimization. You’ll learn how to hack your nervous system using real-time biometric data, how frequency compositions are changing functional medicine, and why sound is emerging as one of the most powerful too…
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NEBC's Terence Murphy on Life, Leadership, and Lending a Hand
9:38
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9:38Angela welcomes back Terence Murphy, President Emeritus and Administrator of the New England Buying Consortium, for a wide-ranging conversation that goes far beyond the bookstore shelves. Terence shares his unique journey from serving in the army to becoming a key figure in the academic retail world, and why he still finds his job both meaningful a…
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Carl Jung and The Most Important Rule of Life
10:55
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10:55Marie-Louise von Franz was a Swiss psychologist who closely collaborated with Carl Jung from 1933 until his death in 1961. One of von Franz’s primary topics of interest was fairy tales. For like myths, fairy tales contains timeless wisdom that teaches us about the human condition. Jung believed that so much wisdom was contained in […] The post Carl…
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How To change ANY Habit In 63 Seconds (No Willpower Needed) : 1307
59:15
59:15
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59:15You’ve been lied to about how long it takes to change a habit. This episode reveals a powerful, science-backed method to rewire your brain in just 63 seconds—without relying on willpower. You’ll discover how to use the 63-second window to interrupt destructive thought loops and how true habit change requires 63-day habit formation, not the populari…
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Innovating On The Frontier Of Radiopharmaceuticals With RadioMedix's Ebrahim Delpassand, M.D.
54:07
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54:07We love to hear from our listeners. Send us a message. On this week's episode, Ebrahim Delpassand, M.D., founder, CEO, and chairman of the board at RadioMedix talks about his personal journey standing up and growing a radiopharmaceutical company focused on oncology. Dr. Delpassand discusses the current trends in radiopharmaceutical drug development…
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Who Should Take Herbal Ecstasy Supplements? (The Billion-Dollar Backstory) : 1306
59:12
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59:12What is Herbal Ecstasy—and why does it matter? This might be one of the most insane episodes we’ve ever recorded, and we had to bring it back because the story is too wild, too relevant, and too packed with real lessons in biohacking, brain optimization, and supplement hacking to miss. Host Dave Asprey sits down with Shaahin Cheyene, the renegade t…
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Boost Brain Power by 25% WITHOUT a Pill (Brain Optimization Secrets) : 1305
1:10:55
1:10:55
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1:10:55You’re leaving brainpower on the table, and this episode shows you how to reclaim it. Learn how to boost cognitive performance by 25% without relying on pills, stimulants, or gimmicks. Host Dave Asprey sits down with global finance expert and cross-cultural thinker Richard Conrad to explore how your cultural programming shapes your biology, metabol…
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The Biohacking Tool That Will Change the World (Mitochondrial Transfusions) : 1304
54:24
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54:24This may be the most cutting-edge life extension technology you’ll hear about for decades. You’ll discover how mitochondrial transfusion, rejuvenation, and repair could reverse biological aging, supercharge your metabolism, and radically extend healthspan—all by upgrading the cellular energy systems that power every function in your body. Watch thi…
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Building An Efficient Biopharma With South Rampart Pharma's Hernan Bazan, M.D.
45:41
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45:41We love to hear from our listeners. Send us a message. On this week's episode, Dr. Hernan Bazan, M.D., co-founder and CEO at New Orleans-based South Rampart Pharma, talks about building an ultra-lean drug development company to address an unmet need observed in his own patients as a surgeon: safe treatments for acute pain. Dr. Bazan explains his st…
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The Fastest-Acting Nootropic I’ve Ever Used : 1303
46:00
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46:00What if one spray could upgrade your brain, protect your mitochondria, and outperform IV therapy and liposomal supplements? In this episode, you’ll discover the breakthrough science behind topical glutathione delivery that uses your skin’s water channels to raise intracellular glutathione levels in just 60 seconds. Learn how this powerful antioxida…
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Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway) : 1302
53:57
53:57
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53:57If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal why this overlooked molecule controls your blood flow, mitochondrial energy, neuroplasticity, insulin response, and even your libido. You’ll learn how n…
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Easy Oxygen Hacking for Mitochondria (The 15-Minute Upgrade) : 1301
49:51
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49:51Supercharge your mitochondria, slash inflammation, and boost energy with one of the most overlooked hacks in human performance. This episode reveals how just 15 minutes of oxygen-based exercise can radically improve metabolism, brain optimization, and even reverse chronic conditions, without expensive gear or endless protocols. Watch this episode o…
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The Business And Science Of Obesity With Roger Cone, Ph.D., Founder Of Courage Therapeutics
54:23
54:23
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54:23We love to hear from our listeners. Send us a message. On this week's episode, Roger Cone, Ph.D., Founder and Chair of the Scientific Advisory Board at Courage Therapeutics, talks about discovering obesity-related protein receptors in the brain, how he spun his academic discoveries out into a biotech company developing new obesity drugs, the need f…
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The Psychology of War – Are We Doomed to Destroy Ourselves?
20:37
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20:37“Will men be able to give up toying with the idea of another war? It is now a question of existence or nonexistence. . .For the danger that threatens us now is of such dimensions as to make this last European catastrophe [i.e., World War II] seem like a curtain-raiser.” Carl Jung, Epilogue to “Essays […] The post The Psychology of War – Are We Doom…
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Facelifts, Breast Implants, and the REAL Fix for Wrinkles : 1300
57:25
57:25
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57:25Wrinkles are just the surface. This episode reveals what’s really happening beneath your skin and how to reverse it using stem cells, regenerative medicine, and the most advanced techniques in plastic surgery and aging. You’ll learn how to improve facial skin tightening, reduce inflammation, and trigger deep skin rejuvenation with stem cells, red l…
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Bold Science, Bigger Bets: Mathai Mammen on Visionary R&D and Transforming Biopharma
50:20
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50:20In this insightful episode of IDEA Collider, Mike welcomes Mathai Mammen, Chairman and CEO of Parabilis Medicines. Mathai shares his extensive journey through academia, MD PhD program at Harvard, co-founding Theravance, and leadership roles at Merck and J&J. They delve into Mathai's innovative approach to creating transformative medicines, navigati…
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Superintelligence, Transhumanism & Biohacking in 2027 : 1299
1:17:52
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1:17:52Superintelligence is coming faster than anyone predicted. In this episode, you’ll learn how to upgrade your biology, brain, and consciousness before AI and transhumanism reshape the future of health. Host Dave Asprey sits down with Soren Gordhamer, founder of Wisdom 2.0, to explore what superintelligence in 2027 means for your mind, body, and soul.…
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BoB Live At BIO: Amber Salzman, Ph.D., Epicrispr Biotechnologies
32:56
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32:56We love to hear from our listeners. Send us a message. This week's episode is one from the road, recorded in front of a live audience in Boston's Seaport neighborhood during the BIO conference (special thanks to MasterControl for making it happen). Amber Salzman, Ph.D., CEO of Epicrispr Biotechnologies (aka 'Epic Bio') explains how epigenetic editi…
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Why I Add Creatine to My Coffee Every Morning (And You Should Too) : 1298
30:41
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30:41Creatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episode reveals why creatine is a non-negotiable supplement for anyone serious about biohacking, longevity, and cognitive upgrades. Watch this episode on Yo…
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Death, Legacy & the Philosophy of Longevity — with Stephen Cave : 1297
57:09
57:09
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57:09What if death isn’t inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You’ll learn why some of today’s top thinkers are treating longevity as both a science and a spiritual movement, and how this shift affects your brain, your mitochondri…
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How To Be A Policy Advocate For Biotech With NewYorkBIO's Jennifer Hawks Bland
56:34
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56:34We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Jennifer Hawks Bland, CEO of NewYorkBIO, shares insights on New York State's life sciences ecosystem while reflecting on her journey from Capitol Hill to biotech advocacy. Her experiences in politics, law, and biopharma government affairs uniqu…
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Fix What’s Making You Feel Old—From Joints to Mitochondria | Dr. Greg Kelly : 1296
45:39
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45:39You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden causes of early aging like mitochondrial dysfunction, leaky gut, and chronic inflammation. Watch this episode on YouTube for the full video experience:…
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The Ultimate Guide to a Metabolism That Burns Fat Again — with Ben Azadi : 1295
1:06:15
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1:06:1593% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap to reboot your metabolism, escape the sugar-burning trap, and reignite your fat-burning engine for good. Watch this episode on YouTube for the full vi…
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Why are People so Obedient? – Compliance and Conformity
12:32
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12:32“And the word “courage” should be reserved to characterize the man or woman who leaves the infantile sanctuary of the mass mind.” Sam Keen, Fire in the Belly In the privacy of our minds many of us disagree with the ideologies, political agendas, and government mandates of our day, yet in public we comply. We […] The post Why are People so Obedient?…
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Why Your Workouts Aren’t Giving You a Summer Body — with Nick Bare : 1294
49:23
49:23
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49:23You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do instead. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with performance-dr…
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FDA Trials And Tribulations With Connect Biopharma's Barry Quart
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1:04:33We love to hear from our listeners. Send us a message. On this week's episode, Barry Quart, CEO of Connect Biopharma, weighs in on the current state of engagement between drug developers and the FDA, and how that key relationship continues to evolve under new leadership. Barry also discusses moving the company from China to San Diego, why a U.S. fi…
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Bridging Clinical Practice and Biotech: Paul Peter Tak's Transformative Journey
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49:58In this episode of Idea Collider, host Mike Rea interviews Paul Peter Tak, CEO of Candel Therapeutics, discussing his remarkable journey from a clinician in Amsterdam to leading cutting-edge biotech companies. Paul shares pivotal moments in his career, the challenges of transitioning from academia to big pharma, and the innovative principles he app…
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