Best Hotter Project Podcasts (2025)

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926: AI is Disrupting the Legal Industry: Are Paralegals Doomed? 4:47

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2d ago4:47

4:47

In this Five-Minute Friday, Jon Krohn explores how AI is reshaping the legal industry. He investigates how AI tools are helping lawyers make conclusions faster, how paralegals are being retrained, and the latest in-demand role in law (hint: It concerns AI). Listen to hear how Harvey AI and Thomson Reuters’ CoCounsel are using AI to help lawyers get…

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#828: David Senra — How Extreme Winners Think and Win: Lessons from 400+ of History’s Greatest Founders and Investors (Including Buffett, Munger, Rockefeller, Jobs, Ovitz, Zell, and Names You Don’t Know ... 2:55:55

4d ago2:55:55

2:55:55

David Senra is the host of the Founders podcast. For the past nine years, David has intensely studied the life and work of hundreds of history’s greatest entrepreneurs. His new podcast, David Senra, showcases conversations with the best-of-the-best living founders and extreme winners. This episode is brought to you by: Cresset family office service…

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David Senra — How Extreme Winners Think and Win: Lessons from 400+ of History’s Greatest Founders and Investors (Including Buffett, Munger, Rockefeller, Jobs, Ovitz, Zell, and Names You Don’t Know But ...

4d ago

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“If you could summarize nine years, 400 biographies into one word of what I’ve learned is: focus.” — David Senra David Senra (@FoundersPodcast) is the host of the Founders podcast. For the past nine years, David has intensely studied the life and work of hundreds of history’s greatest entrepreneurs. Every week he reads another biography and shares …

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925: AI, Automation and the Future of Work, with Oxford’s Prof. Carl Benedikt Frey 1:10:06

5d ago1:10:06

1:10:06

Tech innovation’s dependence on economic systems, trust in technology throughout history, and job displacement through AI: The Dieter Schwartz Associate Professor of AI and work at the University of Oxford, Carl Benedikt Frey, talks to Jon Krohn about his latest book, How Progress Ends, as well as how different economic systems deal with innovation…

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924: 95% of Enterprise AI Projects Fail (Per MIT Research) 5:27

9d ago5:27

5:27

MIT lab NANDA (“Networked AI Agents in Decentralized Architecture”) reveals less than promising results for the future of AI adoption in businesses. According to “The GenAI Divide: State of AI in Business 2025”, a whopping 95% of enterprise AI projects “are getting zero return” on their $30-40 billion investment. Jon Krohn takes this Five-Minute Fr…

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Pablos Holman — One of the Scariest Hackers I’ve Ever Met (#827)

8d ago

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Pablos Holman (@pablos) is a hacker and inventor and the bestselling author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and helped build The Intellectual Ventures Lab to invent a wide variety of breakthroughs, including a brain surgery tool, a machine…

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#827: Pablos Holman — One of The Scariest Hackers I’ve Ever Met 2:31:41

11d ago2:31:41

2:31:41

Pablos Holman is a hacker and inventor and the author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and helped build The Intellectual Ventures Lab to invent a wide variety of breakthroughs. Pablos also hosts the Deep Future Podcast and is managing partn…

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923: Graph Algorithms, GraphRAG and Causal Graphs, with Graph Guru Amy Hodler 1:03:47

12d ago1:03:47

1:03:47

Graphs, but not as you would expect them: Graph analytics guru Amy Hodler speaks to Jon Krohn about the graph data structure and graph applications, graph algorithms, graph RAG, and graphs as memory systems for AI agents. We can use graphs in a surprising number of ways. Money laundering and fraud, as well as supply-chain crime, leave breadcrumbs a…

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922: AI for Manufacturing and Industry, with Hugo Dozois-Caouette 28:29

16d ago28:29

28:29

Hugo Dozois-Caouette speaks to Jon Krohn about his startup MaintainX and how he secured $254 million in venture capital, reaching a $2.5 billion valuation. MaintainX builds computerized maintenance management systems (CMMS) and enterprise asset management (EAM) software for industrial and manufacturing companies. This "digital clipboard" delivered …

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Q&A with Tim — Supplements I’m Taking, Austin vs. SF, Training for Mental Performance, Current Go-To AI Tools, Recovering from Surgery, Intermittent Fasting, and More (#826)

19d ago

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Welcome back to another in-between-isode, with one of my favorite formats: the good old-fashioned Q&A. I answer questions submitted by the small-but-elite group of test readers of my upcoming THE NO BOOK. The community is closed for new members, as we have the right number of people now, but I hope to potentially expand it, once the book comes out.…

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#826: Q&A with Tim — Supplements I’m Taking, Austin vs. SF, Training for Mental Performance, Current Go-To AI Tools, Recovering from Surgery, Intermittent Fasting, and More 1:25:12

19d ago1:25:12

1:25:12

This episode is a solo Q&A session where I answer a bunch of questions. We covered a ton of ground, from personal health protocols to professional frameworks and creative projects. This episode is brought to you by: Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very …

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921: NPUs vs GPUs vs CPUs for Local AI Workloads, with Dell’s Ish Shah and Shirish Gupta 1:12:12

19d ago1:12:12

1:12:12

Using Windows for AI development and the bleeding edge of NPUs: Shirish Gupta and Ish Shah from Dell Technologies speak to Jon Krohn about the latest products from Dell, the future of neural-processing units (NPUs), and how AI developers can make sound hardware investments. This episode is brought to you by the Trainium2, the latest AI chip from AW…

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The Sun Is Having Its Day 48:22

15d ago48:22

48:22

”In the midst of a lot of big, bad things happening, there's one big good thing happening on planet Earth right now.” Today on A Matter of Degrees, we’re bringing back the podcast’s very first guest — legendary activist and author Bill McKibben. Bill’s latest book, Here Comes the Sun: A Last Chance for the Climate and a Fresh Chance for Civilizati…

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920: In Case You Missed It in August 2025 21:57

23d ago21:57

21:57

This month’s episode of In Case You Missed It gives us reasons to be cautiously optimistic about the future of large language models (LLMs), with guests discussing what to do about recent reports that found AI agents blackmailed human users when threatened, the importance of post-training LLMs, and the training we have available for data and AI eng…

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Episode 47: buddhist gender melt 45:35

21d ago45:35

45:35

Fresh back from an LGBTQ+ silent meditation retreat, Mary has some big questions on their mind. When and where do you feel your gender disappearing? Is that a good feeling - and, in a world of containers & labels, is it one we should seek more? Plus, special guest Cec talks about their upcoming top surgery and has an exciting event announcement! Co…

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Dr. Dominic D’Agostino — All Things Ketones, How to Protect the Brain and Boost Cognition, Sardine Fasting, Diet Rules, Revisiting Metformin and Melatonin, and More (#825)

25d ago

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Dr. Dominic D’Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition. He teaches medical neuroscience, physiology, nutrition, and ne…

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#825: Dr. Dominic D’Agostino — All Things Ketones, How to Protect the Brain and Boost Cognition, Sardine Fasting, Diet Rules, Revisiting Metformin and Melatonin, and More 1:54:59

25d ago1:54:59

1:54:59

Dr. Dominic D’Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition. This episode is brought to you by: Helix Sleep premium mattres…

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919: Hopes and Fears of AGI, with All-Time Bestselling ML Author Aurélien Géron 1:29:51

26d ago1:29:51

1:29:51

PyTorch, AGI, and the future of alignment research: Aurélien Géron joins Jon Krohn in this live interview to talk about the fourth edition of his bestselling Hands-On Machine Learning as well as what superintelligence makes him hopeful for, as well as what concerns him about machines surpassing human intelligence. This episode is brought to you by …

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918: Multi-Agent Systems with CrewAI 9:16

30d ago9:16

9:16

In this Five-Minute Friday, Jon Krohn introduces listeners to CrewAI, an open-source Python framework that can create and manage multi-agent teams. The clue is in the title: CrewAI assembles specialized agents into single “crews” that achieve complex goals between them. CrewAI’s agent teams can also learn and iterate, meaning that after the crew ha…

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What Most Has My Attention Right Now — Credible (vs. Bogus) Vagus Nerve Stimulation (#824)

1M ago

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Kevin J. Tracey, MD (@KevinJTraceyMD), is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus-nerve research, and author of the recent book The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes. His contributions include identifying the therapeutic action o…

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#824: What Most Has My Attention Right Now — Credible (vs. Bogus) Vagus Nerve Stimulation 2:23:18

1M ago2:23:18

2:23:18

Kevin J. Tracey, MD is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus nerve research and author of the recent book, The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes. This episode is brought to you by: Eight Sleep Pod Cover 5 sleeping solution for …

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917: 8 Steps to Becoming an AI Engineer, with Kirill Eremenko 1:15:33

1M ago1:15:33

1:15:33

Founder of SuperDataScience, Kirill Eremenko, talks to Jon Krohn about how he found the best tools and approaches to help launch his 8-week AI engineering bootcamp. He breaks down the topics participants cover each week, and he also shares his tips with listeners who might want to start their own tech bootcamp or sign up for SuperDataScience’s Sept…

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Cash In On Clean Tech Incentives (Before It's Too Late) 37:08

30d ago37:08

37:08

Donald Trump’s so-called “One Big Beautiful Bill Act” took a sledgehammer to U.S. climate policy, including tax credits for clean cars and appliances. These incentives were helping people cut pollution, lower their energy bills, and make their homes more comfortable. Trump’s bill eliminates the credits by the end of this year. Wait, don’t change th…

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916: The 5 Key GPT-5 Takeaways 9:40

1M ago9:40

9:40

GPT-5 has just been released, but with not very much fanfare. In this Five-Minute Friday, Jon Krohn asks if GPT-5 deserves the community’s underwhelmed response to its release. He outlines five features of the model and explains why people might be feeling less than enthusiastic in the broader context of LLM development. Which LLMs are leading the …

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Dr. Jeffrey Goldberg — Creating Supranormal Vision, Cutting-Edge Science for Eye Health, Supplements, Red Light Therapy, and The Future of Eyesight Restoration (#823)

1M ago

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Dr. Jeffrey Goldberg is chair of the Department of Ophthalmology and director of the Byers Eye Institute at Stanford University. He is a leading scientist in the development and degeneration of the visual system from eye to brain and a professor, practicing ophthalmologist, and surgeon. Dr. Goldberg is a member of the National Academy of Medicine a…

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#823: Dr. Jeffrey Goldberg — Creating Supranormal Vision, Cutting-Edge Science for Eye Health, Supplements, Red Light Therapy, and The Future of Eyesight Restoration 1:44:33

1M ago1:44:33

1:44:33

Dr. Jeffrey Goldberg is Professor and Chair of Ophthalmology and Director of the Byers Eye Institute at Stanford University, a leading scientist in the development and degeneration of the visual system from eye to brain, and a practicing ophthalmologist and surgeon. This episode is brought to you by: Gamma AI design partner for effortless presentat…

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915: How to Jailbreak LLMs (and How to Prevent It), with Michelle Yi 1:09:33

1M ago1:09:33

1:09:33

Tech leader, investor, and Generationship cofounder Michelle Yi talks to Jon Krohn about finding ways to trust and secure AI systems, the methods that hackers use to jailbreak code, and what users can do to build their own trustworthy AI systems. Learn all about “red teaming” and how tech teams can handle other key technical terms like data poisoni…

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914: Data Lakes 101 (and Why They’re Key for AI Models), with Oz Katz 25:52

1M ago25:52

25:52

In this Five-Minute Friday, Cofounder and CTO of lakeFS Oz Katz talks to Jon Krohn about data warehouses, data lakes, and how companies can handle increasingly complex data infrastructures and formats. Hear about lakeFS’s collaboration with Legofest, lakeFS’s approach to helping users collaborate on data lakes, and how to overcome the challenges of…

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The Random Show — Ketones for Cognition, Tim’s Best Lab Results in 10+ Years, How Kevin Hit 100 Days Sober, Home Defense, Vibe Coding Unleashed, and More (#822)

2M ago

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Welcome to another wide-ranging “Random Show” episode I recorded with my close friend Kevin Rose (digg.com)! We cover Kevin’s sobriety journey and marking 100 days without alcohol, my results with the ketogenic diet and intermittent fasting, GLP-1 agonists, home defense and security, the future of Venture Capital, authenticating yourself online, AI…

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#822: The Random Show — Ketones for Cognition, Tim’s Best Lab Results in 10+ Years, How Kevin Hit 100 Days Sober, Home Defense, Vibe Coding Unleashed, and More 2:07:46

2M ago2:07:46

2:07:46

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)! We cover Kevin's sobriety journey and marking 100 days without alcohol, my results with the ketogenic diet and intermittent fasting, GLP-1 agonists, home security, the future of Venture Capital, AI, authenticating yourself online in a w…

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913: LLM Pre-Training and Post-Training 101, with Julien Launay 1:15:16

2M ago1:15:16

1:15:16

Julien Launay launched Adaptive to give data science teams in business enterprises their “RLOps tooling” to make reinforcement learning easier. Talking to Jon Krohn, Julien says, “Most of our users are data scientists who write Python codes to interface with the system”. Adaptive is also able to work with companies without data science teams, colla…

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912: In Case You Missed It in July 2025 32:38

2M ago32:38

32:38

In this episode of In Case You Missed It, we look back on five great interview episodes from July. Hear from Lilith Bat-Leah (Episode 901), Sinan Ozdemir (Episode 903), Sebastian Gehrmann (Episode 905), Zohar Bronfman (Episode 907) and Robert Ness (Episode 909). They’ll tell you why data-centric machine learning is so important across disciplines, …

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My Two-Year Secret Project, COYOTE — The Strategies and Tactics for Building a Bestseller from Nothing with Elan Lee of Exploding Kittens (#821)

2M ago

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This is a very special episode for me, one I’ve been looking forward to publishing for months. COYOTE is a fast, casual card game I created with the amazing Elan Lee and Exploding Kittens team. It has been my obsession for two years. Here is a demo: I worked really hard on every aspect of this one (concept, mechanics, art, you name it)! You can fin…

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#821: My Two-Year Secret Project, COYOTE — The Strategies and Tactics for Building a Bestseller from Nothing with Elan Lee of Exploding Kittens 3:00:18

2M ago3:00:18

3:00:18

This is a very special episode for me. My brand-new card game, COYOTE, created in collaboration with Elan Lee and Exploding Kittens, is here. It is available in ~8,000 locations worldwide, including Walmart, Target, Amazon, and many others. Learn more: https://coyotegame.com. This episode is brought to you by: Gamma AI design partner for effortless…

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911: The Future of Python Notebooks is Here, with Marimo’s Dr. Akshay Agrawal 58:20

2M ago58:20

58:20

Reproducibility, Python notebooks, and data science communities: Software developer Akshay Agrawal speaks to Jon Krohn about Marimo, the next-generation computational notebook for Python, how he built and fostered a thriving community around the product, and what makes this notebook so versatile and accessible for users. Additional materials: ⁠⁠⁠⁠⁠…

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910: AI is Disrupting Journalism: The Good, The Bad and The Opportunity 10:24

2M ago10:24

10:24

In this Five-Minute Friday, Jon Krohn looks into AI’s disruption of the journalism industry and how it has fundamentally reshaped news production. Multiple news outlets’ suing of ChatGPT over its use of copyrighted materials may have taken the most headlines to date, but this isn’t to say news media is rebuffing AI entirely. On the contrary, severa…

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#820: Elizabeth Gilbert — How to Find Your Inner Voice, Set Strong Boundaries, and Live a Life of Radical Ease (Repost) 1:56:02

2M ago1:56:02

1:56:02

Elizabeth Gilbert is the #1 New York Times bestselling author of Big Magic and Eat, Pray, Love as well as several other international bestsellers. Her latest novel, City of Girls, was named an instant New York Times bestseller. Go to ElizabethGilbert.Substack.com to subscribe to “Letters From Love with Elizabeth Gilbert,” her newsletter, which has …

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909: Causal AI, with Dr. Robert Usazuwa Ness 1:22:27

2M ago1:22:27

1:22:27

Researcher at Microsoft Robert Usazuwa Ness talks to Jon Krohn about how to achieve causality in AI with correlation-based learning, the right libraries, and handling statistical inference. When dealing with causal AI, Robert notes how important it is to keep aware of variables in the data that may mislead us and force inaccurate assumptions. Not a…

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908: AI Agents Blackmail Humans 96% of the Time (Agentic Misalignment) 8:50

2M ago8:50

8:50

The moral and ethical implications of letting AI take the wheel in business, as revealed by Anthropic: Jon Krohn looks into Anthropic’s latest research on how to use and deploy LLMs safely, specifically in business environments. The team designed scenarios to test the behavior of AI agents when given a goal and a set of obstacles to reach it. Those…

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Rhonda Patrick, Ph.D. — Protocols for Fasting, Lowering Dementia Risk, Reversing Heart Aging, Using Sauna for Longevity (Hotter is Not Better), and a Few Supplements That Might Actually Matter (#819)

2M ago

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Rhonda Patrick, Ph.D. (@foundmyfitness) is a biomedical scientist and the founder of FoundMyFitness, a platform dedicated to delivering rigorous, evidence-based insights on improving healthspan and mitigating age-related diseases. Through her podcast, website, and YouTube channel, reaching millions globally, she translates complex science into acti…

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#819: Rhonda Patrick, Ph.D. — Protocols for Fasting, Lowering Dementia Risk, Reversing Heart Aging, Using Sauna for Longevity (Hotter is Not Better), and a Few Supplements That Might Actually Matter 2:31:28

2M ago2:31:28

2:31:28

Rhonda Patrick, Ph.D. (@foundmyfitness) is a biomedical scientist and the founder of FoundMyFitness, a platform dedicated to delivering rigorous, evidence-based insights on improving healthspan and mitigating age-related diseases. Sponsors: Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders) Momentous high-quali…

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907: Neuroscience, AI and the Limitations of LLMs, with Dr. Zohar Bronfman 1:21:16

2M ago1:21:16

1:21:16

“Intelligence has many forms,” says Zohar Bronfman, who speaks with Jon Krohn about the fascinating intersection between computational neuroscience and philosophy, and how it has brought him closer to understanding what is necessary to develop human-like intelligence in machines, as well as his motivations for launching Pecan AI and why predictive …

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906: How Prof. Jason Corso Solved Computer Vision’s Data Problem 29:29

2M ago29:29

29:29

Jason Corso speaks to Jon Krohn in this Five-Minute Friday all about Voxel51’s latest tool, Verified Auto-Labelling, and the company’s incredible success in developing popular tools for computer vision. Additional materials: ⁠⁠⁠⁠⁠⁠⁠www.superdatascience.com/906⁠ Interested in sponsoring a SuperDataScience Podcast episode? Email natalie@superdatascie…

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905: Why RAG Makes LLMs Less Safe (And How to Fix It), with Bloomberg’s Dr. Sebastian Gehrmann 57:49

3M ago57:49

57:49

RAG LLMs are not safer: Sebastian Gehrmann speaks to Jon Krohn about his latest research into how retrieval-augmented generation (RAG) actually makes LLMs less safe, the three ‘H’s for gauging the effectivity and value of a RAG, and the custom guardrails and procedures we need to use to ensure our RAG is fit-for-purpose and secure. This is a great …

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904: A.I. is Disrupting the Entire Advertising Industry 9:14

3M ago9:14

9:14

In this Five-Minute Friday, Jon Krohn reveals how AI is taking on the glitzy world of advertising. Bold claims from Meta and OpenAI contend that users will soon be able to plug in what they want and have AI churn out an ad campaign for little to no cost are shaking the advertising industry to its core. The fact that the four biggest sellers of ads …

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903: LLM Benchmarks Are Lying to You (And What to Do Instead), with Sinan Ozdemir 1:28:20

3M ago1:28:20

1:28:20

Has AI benchmarking reached its limit, and what do we have to fill this gap? Sinan Ozdemir speaks to Jon Krohn about the lack of transparency in training data and the necessity of human-led quality assurance to detect AI hallucinations, when and why to be skeptical of AI benchmarks, and the future of benchmarking agentic and multimodal models. Addi…

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902: In Case You Missed It in June 2025 29:29

3M ago29:29

29:29

In this episode of “In Case You Missed It”, Jon recaps his June interviews on The SuperDataScience Podcast. Hear from Diane Hare, Avery Smith, Kirill Eremenko, and Shaun Johnson as they talk about the best portfolios for AI practitioners, how to stand out in a saturated candidate market for AI roles, how to tell when an AI startup is going places, …

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John Arnold with Dr. Peter Attia — The Greatest Energy Trader of All Time on Lessons Learned, Walking Away from Wall Street, and Reinventing Philanthropy (#818)

3M ago

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In this special episode, my friend—and fan-favorite guest—Dr. Peter Attia takes the mic as guest host. Peter sits down with legendary trader John Arnold, widely considered the greatest energy trader of all time. Today, through his foundation Arnold Ventures, John applies the same rigorous thinking to some of America’s toughest social challenges—cri…

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#818: John Arnold with Dr. Peter Attia — The Greatest Energy Trader of All Time on Lessons Learned, Walking Away from Wall Street, and Reinventing Philanthropy 2:36:09

3M ago2:36:09

2:36:09

In this special episode, my friend—and fan-favorite guest—Dr. Peter Attia takes the mic as guest host. Peter sits down with legendary trader John Arnold, widely considered the greatest energy trader of all time. Today, through his foundation Arnold Ventures, John applies the same rigorous thinking to some of America’s toughest social challenges—cri…

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901: Automating Legal Work with Data-Centric ML (feat. Lilith Bat-Leah) 1:06:12

3M ago1:06:12

1:06:12

Senior Director of AI Labs for Epiq Lilith Bat-Leah speaks to Jon Krohn about the ways AI have disrupted the legal industry using LLMs and retrieval-augmented generation (RAG), as well as how the data-centric machine learning research movement (DMLR) is systematically improving data quality, and why that is so important. Additional materials: ⁠⁠⁠⁠⁠…