Conversations with scientists at the forefront of brain research. Hosted by neuroscientist Mark Mattson.
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David Mattson Podcasts
The Wisdom Keepers podcast encourages meaningful and educational interactions between individuals of diverse perspectives and experiences, bringing to light the foundational values we have in common in a shared forum …that bridges people, communities and cultures across Nations and across generations.
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Prime Time 89 is about catching-up with classmates and friends from a generation ago. Finding out how they're doing, where they are, how they got there and what experiences they've had along the way.
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Break free from the ordinary career and learn how to use franchising to launch your entrepreneurial success story. No Guts, No Gain! is hosted by Dave Mattson, the Executive Chairman and President of Franchising at Sandler, who brings you firsthand accounts from Sandler franchisees who have successfully navigated the path to business ownership. We'll uncover their diverse backgrounds, from military service to corporate roles, and gain invaluable insights into what it takes to become your own ...
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Throwback Trivia Takedown is a podcast that pits to contenders head-to-head in a nostalgic trivia match-up.
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We’re a team of doctors with a combined 100 years of experience and a passion for helping patients find long-term vitality using our new approach to medicine. Instead of just trying to lengthen your lifespan, we aim to lengthen your healthspan.
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If you're angry, frustrated, or scared about the state of politics and media and looking for thoughtful, balanced discussions, this podcast is for you. About 30 minutes every few weeks. It will change your life. Outrage Overload explores the extreme polarization and political bias dominating politics and media today. We dive into the anger and outrage that drive divisions between people, distort the news, and fuel political violence. Each episode features leading scientists, researchers, aut ...
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Neurobiology of Aging Lecture #4: Aging and Neurodegenerative Disorders; AD, PD, ALS, and FTD.
1:04:46
1:04:46
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1:04:46In this lecture I describe how changes occurring in the brain during normal aging set contribute to the pathogenesis of Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal dementia. Cellular and molecular hallmarks of aging predispose brain cells to neurodegenerative orders with environmental and genetic fact…
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Ep. 288: Daniela Browning vs. Kristen Berset-Harris
40:08
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40:08Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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BONUS - A Clear-Eyed Look Back at the Pandemic Divide
25:50
25:50
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25:50COVID may be behind us, but many of the frustrations, myths, and political divides it created are still quietly shaping our social and civic landscape. This bonus episode revisits a conversation originally recorded for Outrage Science Bites—now brought to the main feed because its insights remain deeply relevant. We take a calm, evidence-based look…
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Tomás Ryan: Competition Between Memory Engrams and The Importance of Forgetting
54:37
54:37
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54:37During the past decade several new technological advances have enabled the identification of ensembles of neurons that encode a specific memory trace (engram cells) and for controlling the activity of engram cells so that recall or inhibition of a memory is controlled by the experimenter. The technologies include fluorescence 'tagging' of engram ce…
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Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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BONUS - The Congresspeople You’ve Never Heard Of Might Save Democracy – Brad Porteus
31:50
31:50
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31:50While outrage and division dominate the headlines, quiet collaborators in Congress are actually getting things done — you just never hear about them. In this episode, David Beckemeyer talks with Brad Porteus, founder of Bridge Grades, a data-driven “report card for Congress” that measures who’s building bridges — and who’s tearing them down. Togeth…
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#68 – Dr. Stefanos N. Kales | Mediterranean Diet, Lifestyle Medicine & Disease Prevention | Harvard Professor
57:26
57:26
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57:26Send us a text A Harvard professor explains why Mediterranean lifestyle principles—nutrition, sleep, and culture—may be our most powerful tools for preventing chronic disease, especially in high-stress professions. Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they speak with Dr. Stefanos N. Kales, Professor of Medicine at Harvard Medical…
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Shuying Sun: RNA Dysregulation in Neurodegenerative Disorders – From Mechanisms to New Therapies
1:02:28
1:02:28
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1:02:28Recent discoveries show that some neurodegenerative disorders occur because of abnormalities in the processing of RNA in the cell nucleus and/or its export from the nucleus. Johns Hopkins University Associate Professor Shuying Sun is at the forefront of research that is establishing the molecular mechanisms responsible for RNA dysregulation in amyo…
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Ep. 285: Scott Grimes vs Janelle Alvstad-Mattson
46:28
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46:28Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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Neurobiology of Aging Lecture #3: mTOR, Functional and Structural Alterations, and Biomarkers
1:19:09
1:19:09
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1:19:09NOTE: This lecture with slides presented can be found on the Brain Ponderings YouTube Channel. This episode begins by highlighting recent evidence showing adverse effects on the brain of excessive activation of the mTOR pathway as a consequence of dietary branched chain amino acid consumption. Then I describe evidence that Beyond the age of 40 year…
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Neurobiology of Aging Lecture 2: Cellular and Molecular Hallmarks of Brain Aging
1:21:19
1:21:19
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1:21:19NOTE: This lecture with slides presented can be found on the Brain Ponderings YouTube Channel. This video describes 12 major changes that occur in brain cells during aging and their involvement in decline in brain function and the development of neurodegenerative disorders including dementia and Parkinson's disease.…
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Neurobiology of Aging Lecture Series: #1 – Theories, Comparative Biology, and Animal Models of Aging
1:21:18
1:21:18
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1:21:18NOTE: This lecture with slides presented can be found on the Brain Ponderings YouTube Channel. This is the first of five lectures on the Neurobiology of Aging. The other four lectures cover cellular hallmarks, structural and functional aspects, biomarkers, how neurodegenerative disorders occur during aging, and how aging can be slowed and brain hea…
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78. When AI Becomes the Most Persuasive Voice in the Room – Petter Törnberg
41:18
41:18
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41:18When AI Starts Shaping What We Believe We often blame social media algorithms for toxic polarization — for the outrage, the misinformation, the “us versus them” dynamic pulling society apart. But what if the real problem goes deeper than the algorithm? In this episode, University of Amsterdam researcher Petter Törnberg explains why social media is …
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Ep. 284: Scott Anglemeyer vs. Riley Scherer
28:44
28:44
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28:44Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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BONUS - The America You Don’t See on the News – Adam Mizel
36:12
36:12
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36:12Most Americans are tired of the outrage — and hungry for something better. So how do we unite America when everything feels so divided? In this episode, we talk with Adam Mizel, co-founder and CEO of US United, a movement focused on ending toxic polarization through everyday actions anyone can take. After traveling the country in a purple pickup tr…
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Norm Haughey: Membrane Sphingomyelin and Ceramides Abnormalities in Alzheimer's and Other Diseases
55:32
55:32
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55:32The lipid membrane bilayer of cells is composed of fats including phospholipids, cholesterol, and sphingomyelin. Enzymes called sphingomyelinases can cleave sphingomyelin resulting in the liberation of ceramides which can diffuse within the cell and act as signaling molecules. In this episode I talk with Tulane University Professor Norm Haughey abo…
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Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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77. Issue Salience Polarization - Adrienne Kafka & Troy Campbell
30:33
30:33
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30:33Why We Disagree About What Matters We often assume political polarization is about beliefs or party loyalty—but what if it’s about which issues we think are worth caring about? In this episode, behavioral scientists Adrienne Kafka (Duke University) and Troy Campbell (On Your Feet, formerly Disney Imagineering and Netflix) unpack their research on i…
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Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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Okay Boomer – Drowning in Digital Overwhelm - Craig Mattson
18:39
18:39
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18:39Digital Overwhelm: Talking Across Generations In a world that never stops pinging, how do we stay human—and stay connected across generations? Host David Beckemeyer talks with communication scholar Craig Mattson, author of Digital Overwhelm, about what happens when Boomers, Gen X, Millennials, and Gen Z all try to navigate the same flood of digital…
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David Gutmann – Cancer Neuroscience and the Sociobiology of Brain Tumors
59:27
59:27
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59:27Brain tumor cells interact with neurons, glial cells, and immune cells in complex ways that often benefit the cancer cells while compromising the function of normal neural cells. In this episode I talk with Washington University Neurology Professor David Gutmann about brain cancer cells and their communication with surrounding normal cells. A major…
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Ep. 281: Frankie Mitchell vs Hollie Medina
48:04
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48:04Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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76. The Revolt Against the Experts – Hillary Shulman
28:08
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28:08Why People Stop Trusting Science Why do so many people reject science—even when the facts are clear? We are joined by Hillary Shulman, a communication scholar at Ohio State University, to learn about science populism—the growing belief that science is an elite enterprise disconnected from everyday life. They explore how distrust of experts, polariz…
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Ray Dorsey: Environmental Toxins and Parkinson's Disease – Evidence and What to Avoid
57:26
57:26
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57:26There is considerable evidence that exposure to certain chemicals in the environment cause Parkinson's disease in many people. In this episode neurologist Ray Dorsey talks about some of the chemicals that may cause Parkinson's disease including the pesticides paraquat and rotenone, and trichloroethylene and perchloroethylene which are chemicals use…
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#67 – Dr. Sharon J. Parish | Women’s Sexual Health |Professor of Clinical Medicine & Psychiatry at Weill Cornell
1:37:41
1:37:41
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1:37:41Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they speak with Dr. Sharon J. Parish, a nationally recognized leader in women’s sexual health, menopause care, and the integration of emotional and physical well-being. Dr. Parish is a Professor of Clinical Medicine and Psychiatry at Weill Cornell Medicine and has played a key r…
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Ep. 280: David Kantorski vs. Jerry Filbin
34:04
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34:04Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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Ai Yamamoto: "ALFY" Cleanses Neurons of Pathological Proteins to Counteract Degenerative Diseases
1:12:11
1:12:11
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1:12:11A shared feature of neurodegenerative disorders is accumulation of aggregated proteins within neurons: Tau in Alzheimer's disease; alpha-synuclein in Parkinson's disease; huntingtin in Huntington's disease; and TDP43 in amyotrophic lateral sclerosis. In this episode Ai Yamamoto – an Associate Professor Neurology at Columbia University – talks about…
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75. The Hidden Power of the Politically Homeless - Lura Forcum
38:38
38:38
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38:38When the Center Becomes the Rebel Once, being radical meant picking a side—Rush Limbaugh on the right, Keith Olbermann on the left. But today, that kind of partisanship isn’t radical anymore—it’s predictable. In this episode, we explore a surprising idea: maybe the true radicals now are the independent thinkers—the bridge-builders—who refuse to be …
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Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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DOCUMENTARY - The Manosphere: A Shadow Network of Influence – Havana Mohr-Ramirez
40:03
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40:03We take a closer look at the online world known as the manosphere—a loose network of communities including incels, Men Going Their Own Way (MGTOW), men’s rights activists (MRAs), and pick-up artists (PUAs). These groups may look different on the surface, but they share a common core: resentment toward feminism, nostalgia for traditional masculinity…
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Marco Capogrosso – Spinal Cord Stimulation for Recovery of Function After Stroke or Trauma
1:03:16
1:03:16
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1:03:16Remarkable advances are being made in the development and clinical applications of stimulation devices that enable recovery of motor function in patients who have suffered a spinal cord injury, a stroke, and even those with rare disabling genetic disorders. At the forefront of this research is Marco Capogrosso at the University of Pittsburgh. He ha…
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Ep. 277: Stacey Melquist vs Vanessa Roberts
34:34
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34:34Throwback Trivia Takedown takes trivia back to the glory days from the mid 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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74. When Polarized Communities Work Together – Kira Hamman
33:36
33:36
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33:36Why Talking Isn’t Enough to Bridge Divides What happens when people in deeply divided communities set aside differences to work on real problems together? In this episode, we hear from participants in Southern Oregon and from Urban Rural Action’s Senior Director of Programs about how building trust and taking action can bridge divides, create belon…
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#66 – Dr. William Li | Angiogenesis & “Food as Medicine” Authority | President of the Angiogenesis Foundation
1:06:36
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1:06:36Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they interview Dr. William Li, a pioneering physician-scientist, bestselling author, and global leader in the “food as medicine” movement. Dr. Li is the President and Medical Director of the Angiogenesis Foundation, where his groundbreaking work has redefined how we understand f…
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Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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Scott Ayton: Iron, Brain Health, Parkinson's and Alzheimer's Diseases – A Delicate Balance
1:15:26
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1:15:26Dietary iron is essential for health as it plays important roles in the ability of hemoglobin to carry oxygen throughout the body and brain. In addition, iron is involved in various functions in cells including the generation of ATP in mitochondria and DNA synthesis. The vast majority of iron is bound to proteins such as ferritin and heme. However,…
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Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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73. Rethinking Autism Advocacy – Ari Ne’eman
46:29
46:29
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46:29What If Inclusion, Not Normalization, Was the Goal? Too often, conversations about autism happen without autistic voices at the table. In this episode, we talk with Ari Ne’eman, Assistant Professor at Harvard and co-founder of the Autistic Self-Advocacy Network, about the real divides in autism advocacy and what a better path forward could look lik…
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Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia? bfopnetwork.com…
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Erik Musiek: Brain Cell Circadian Clock Proteins in Neuroplasticity, Aging, and Alzheimer's Disease
1:12:00
1:12:00
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1:12:00Health depends upon proper regulation of circadian rhythms of cell and organ functions. Disruption of circadian rhythms has detrimental consequences for brain function and resilience and abnormal circadian rhythms are a common feature of Alzheimer's disease. In this episode neurology professor Erik Musiek talks about the roles of specific circadian…
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Ep. 273: Christian Hernandez vs Mary Randazzo
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34:00Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia?
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72. The Fight to Make Online Spaces Civil Again - Yevgeny Simkin
40:52
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40:52Why Owning Your Online Identity Matters More Than Ever Is it possible to fix social media? In this episode, I’m joined by Yevgeny Simkin, Co-Founder of Sez.us, a new social media platform built to encourage civility and healthier online spaces. We talk about why we need real alternatives to Facebook and Twitter, who controls online conversations to…
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Ep. 272: Philip Sanford vs. Arjun Sivakumar
37:42
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37:42Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia?
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Georgia Hodes: Sex Differences in Responses to Stress and Vulnerability to Neurological Disorders
1:11:08
1:11:08
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1:11:08Chronic uncontrolled stress is a risk factor for many different diseases including mental and neurodegenerative disorders. The effects of such stress on the brain differ considerably between females and males. However, the vast majority of preclinical studies in animal models have included only males which in some cases has resulted in therapeutic …
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DOCUMENTARY - What’s Pulling Young Men to the Right?
34:28
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34:28Gen Z’s political gender gap is widening. Young women are trending left, while young men drift right—and it’s not just politics. In this episode, we explore the cultural, social, and economic pressures shaping young men’s identities, from the “manosphere” to societal expectations around masculinity and the pressure to be the breadwinner. We examine…
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Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious. Do you know your nostalgia?
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Hello everyone, the contest has been won by 4 awesome people: Ian Schulze, Paul McLaughlin, Chris Parkinson, and Chris Panter. Congrats to them! Thank you to everyone who submitted an answer and joined in on the madness.
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We've put together a pop culture scavenger hunt math problem. The first two non-patron winners will receive a year-long membership at the $5 level. The first two current patron winners will receive a set of tumbler (rocks) glasses. Submit the final number you get to [email protected]. If it's correct, great job! If not, you may need…
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71. Do Facts Really Change Minds? – Nick Stagnaro
32:23
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32:23The Shift from Certainty to Nuance We’ve all heard the saying: facts don’t change minds. But new research challenges that idea. In this episode, David talks with social scientist Nick Stagnaro about what happens when people dive deep into the facts on divisive issues like gun control. The findings? Knowledge can soften extreme positions—shifting pe…
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