Best Nathaniel Whittemore Podcasts (2025)

1
The 6 AI Use Case Primitives 21:02

27m ago21:02

21:02

OpenAI just released a new report breaking down the six core ways businesses are using AI today. They call these “AI use case primitives”—the main types of work where AI tools keep showing up: content creation, research, coding, data analysis, ideation and strategy, and automation. NLW shows where they're headed in the emerging era of agents. Get A…

1
Who Can Out-Saylor Saylor? 11:46

2h ago11:46

11:46

Trump Media, GameStop, Joe Lubin, and a growing list of others are embracing the Michael Saylor playbook—raising massive capital to load up on Bitcoin. Today on The Breakdown, NLW unpacks the explosion of MicroStrategy-style public vehicles, the reflexive loop driving investor FOMO, and whether this leverage injection is a new frontier for Bitcoin-…

1
The Big Bank Stablecoin Consortium 11:00

3h ago11:00

11:00

America’s biggest banks are planning a joint stablecoin, signaling a new phase of institutional crypto adoption — but it’s happening just as political backlash intensifies. NLW breaks down the Wall Street consortium’s ambitions, the implications for the U.S. financial system, and how Trump’s meme coin controversy is complicating stablecoin legislat…

1
Is AI Already Shrinking Entry-Level Tech Jobs? 18:05

13h ago18:05

18:05

Is AI starting to cut entry-level tech jobs? New research says entry-level hiring in tech is way down. The State of Talent Report 2025 shows entry-level roles in big tech dropped 25% last year, and are down more than 50% from 2019. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/AIDailyBrief⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
What to Use Claude 4 For 20:31

1d ago20:31

20:31

Anthropic has released Claude Opus 4 and Sonnet 4, their newest AI models. Both are better at long tasks and coding. NLW discusses why the trick with new models isn't to compare general benchmarks, but to figure out how to slot in the specific model for the specific use case. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http…

1
How to Make AI Work at Work 22:30

4d ago22:30

22:30

AI races forward, yet organizations remain behind. In this piece, NLW explores Professor Ethan Mollick's three-part organizational architecture for capturing the gains of AI, arguing that if anything, agents have increased the urgency. Source: https://www.oneusefulthing.org/p/making-ai-work-leadership-lab-and Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
Rick Rubin on Art, Life and Vibe Coding 55:59

6d ago55:59

55:59

Legendary music producer Rick Rubin joins NLW on The AI Daily Brief for a singular conversation about creativity, technology, and how a meme turned into something much deeper. After unexpectedly becoming the internet’s unofficial mascot of “vibe coding,” Rubin leaned into the joke—and emerged with a profound new collaboration: The Way of Code, a Ta…

1
Bitcoin Hits All-Time High — But Nobody Seems to Care 13:23

7d ago13:23

13:23

Bitcoin just notched a new all-time high, but this time, there’s no mania, no frenzy—just a shrug. NLW breaks down the weirdest ATH in Bitcoin’s history, why it happened without a clear catalyst, and what it says about BTC’s shifting role in the global financial system. Plus, a look at Japan’s spiraling bond market, rising U.S. fiscal fears, and wh…

1
OpenA-IPhone? Legendary Designer Joins OpenAI 20:34

7d ago20:34

20:34

OpenAI has purchased the AI hardware design firm of legendary iPhone designer Jony Ive. The plan is, of course, to build AI hardware with fundamentally new form factors. But what exactly that means isn't yet clear. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/AIDailyBrief⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
The Push to Productize AI 18:13

7d ago18:13

18:13

Following Microsoft Build kicking off the announcement week, Google followed with their I/O event. Since they had already recently made lots of big announcements, people wondered if the show would be muted. Instead, Google laid out a comprehensive set of announcements that showed how aggressively they’re trying to productive AI. Get Ad Free AI Dail…

101
Bitcoin Inches Toward History as Politics, Policy, and Memecoins Collide 11:15

8d ago11:15

11:15

Bitcoin hovers just below a new all-time high, with traders bracing for a potential liquidation cascade and analysts divided on what comes next. NLW explores whether upcoming catalysts—ranging from a Trump meme coin gala to SEC regulatory shifts—could break the stalemate. Plus: Robinhood’s big tokenization push, Kraken’s global derivatives expansio…

101
Senate Clears Stablecoin Bill Hurdle 11:13

8d ago11:13

11:13

In a major breakthrough for crypto legislation, the U.S. Senate voted 66-32 to advance the Genius Act—marking the most significant step yet toward stablecoin regulation. NLW breaks down what flipped Democratic support, why Elizabeth Warren fought to the bitter end, and what’s next as the bill moves toward a final vote. Plus, Circle is reportedly ex…

1
Here Comes the Internet of Agents 22:34

8d ago22:34

22:34

Microsoft Build 2025 opened, focusing on AI agents and the open agent web. Announcements included a coding agent for GitHub, Copilot Tuning for company language, and multi-agent orchestration for teams. NLW argues that the biggest news is in the tone: the time for pilots and half-moves is over. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
US Credit Downgrade Hits—Bitcoin Pumps Anyway 13:34

10d ago13:34

13:34

Moody’s has officially downgraded the U.S. credit rating, joining S&P and Fitch in knocking the government off its AAA pedestal. NLW breaks down the political reaction, the muted market response, and why institutional investors still seem bullish on Bitcoin despite fiscal dysfunction. Plus, what rising transaction fees and ETF flows reveal about th…

1
The Five Vectors of AI Competition 24:15

9d ago24:15

24:15

With Microsoft Build, Google I/O, and Code with Claude all happening this week, the battle between major AI labs is heating up. This episode breaks down how to think about the AI race across five key vectors: Consumer, Enterprise, Coding, Agents, and Benchmarks. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/AID…

1
When Investors Should Say "No" vs. "Yes" 10:16

11d ago10:16

10:16

A reading and discussion inspired by https://blockworks.co/news/investors-prediction-market-no-bet-outcome Enjoying this content? SUBSCRIBE to the Podcast: https://pod.link/1438693620 Watch on YouTube: https://www.youtube.com/@TheBreakdownBW Subscribe to the newsletter: ⁠⁠https://blockworks.co/newsletter/thebreakdown⁠⁠ Join the discussion: https://…

1
The Vibe Coding Landscape 2025 13:56

11d ago13:56

13:56

Vibe coding is among the biggest AI themes and trends of the year, opening up incredible new possibilities for creation. But what's the difference between the various platforms? Based on a recent LinkedIn essay by Nufar Gaspar, NLW breaks it down. Source: https://www.linkedin.com/posts/nufar-gaspar-76b7424b_the-vibe-coding-revolution-isnt-about-bui…

1
The Five Most Important Stories in Crypto This Week 18:58

12d ago18:58

18:58

This week’s Friday Five is a whirlwind tour through one of the most bullish weeks for crypto on Wall Street in recent memory. NLW and Scott Melker break down Coinbase’s historic addition to the S&P 500, Galaxy’s NASDAQ uplisting, and eToro’s surprisingly strong IPO. They also cover a surprisingly soft inflation print, new Bitcoin treasury players r…

1
The "Wave of Crazy New AI Stuff" Coming Next Month 22:24

13d ago22:24

22:24

A flood of major AI updates is right around the corner. New models from Anthropic, OpenAI’s autonomous coding agent Codex, Windsurf's SWE-1 for end-to-end software engineering, and changes at Salesforce and Walmart all point to a massive shift. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/AIDailyBrief⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
How AI Is Already Changing Jobs 20:34

14d ago20:34

20:34

AI is transforming the job market, reshaping roles from software engineers to customer service agents. Microsoft's layoffs spotlight how AI may replace middle management and coding jobs, while companies like Klarna and Duolingo navigate the balance between AI efficiency and human interaction. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
As eToro IPO Pops is Wall Street Getting Crypto Fever? 11:21

14d ago11:21

11:21

eToro's successful NASDAQ debut signals renewed investor appetite for crypto-focused companies, potentially reopening the IPO window for others like Kraken and Circle. Meanwhile, traditional finance giants JPMorgan and Standard Chartered accelerate their blockchain integrations, highlighting growing convergence with crypto. Plus, Bitcoin treasury c…

1
5 Questions Shaping the Near Future of Crypto and Macro 18:28

15d ago18:28

18:28

Blockworks announced that we're bringing together their daily newsletter together with The Breakdown brand to build the best daily content package in crypto. In celebration of that, NLW is joined by Byron Gilliam to discuss some of the big explorations of the moment. Find Byron on X: https://x.com/bgilliam1982 Subscribe to the Newsletter: https://b…

1
The Age of AI Diplomacy 18:27

15d ago18:27

18:27

AI is becoming a central pillar of geopolitical strategy, as highlighted by a series of landmark AI deals announced during a major US-Saudi investor summit. With participation from leaders like Elon Musk, Sam Altman, and Jensen Huang, Saudi Arabia is poised to build out significant AI infrastructure. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…

1
What to Use Different AI Models For 22:21

16d ago22:21

22:21

If you’ve ever stared at OpenAI’s model selector and thought, “Which one am I supposed to use?”, this episode breaks it all down. We go through when to use GPT-4o, GPT-4.5, o3, o4-mini, o4-mini-high, and o1 pro, all based on real world business scenarios. Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/AIDailyBrief⁠⁠⁠…

1
Coinbase Joins the S&P 500 as Bitcoin and Traditional Finance Converge 10:06

16d ago10:06

10:06

Coinbase has officially become the first crypto company added to the S&P 500, signaling a new era of legitimacy for crypto in traditional finance. Meanwhile, Bitcoin's increasing acceptance is marked by Goldman Sachs ramping up client exposure, Galaxy Digital's upcoming NASDAQ listing, and Nakamoto Holdings going public. NLW explores how these deve…

Podcasts Worth a Listen

Nathaniel Whittemore Podcasts

Podcasts Worth a Listen

1
The AI Daily Brief (Formerly The AI Breakdown): Artificial Intelligence News and Analysis

Nathaniel Whittemore

1
The Breakdown

Blockworks

1
The 6 AI Use Case Primitives 21:02

1
Who Can Out-Saylor Saylor? 11:46

1
The Big Bank Stablecoin Consortium 11:00

1
Is AI Already Shrinking Entry-Level Tech Jobs? 18:05

1
What to Use Claude 4 For 20:31

1
How to Make AI Work at Work 22:30

1
Rick Rubin on Art, Life and Vibe Coding 55:59

1
Bitcoin Hits All-Time High — But Nobody Seems to Care 13:23

1
OpenA-IPhone? Legendary Designer Joins OpenAI 20:34

1
The Push to Productize AI 18:13

101
Bitcoin Inches Toward History as Politics, Policy, and Memecoins Collide 11:15

101
Senate Clears Stablecoin Bill Hurdle 11:13

1
Here Comes the Internet of Agents 22:34

1
US Credit Downgrade Hits—Bitcoin Pumps Anyway 13:34

1
The Five Vectors of AI Competition 24:15

1
When Investors Should Say "No" vs. "Yes" 10:16

1
The Vibe Coding Landscape 2025 13:56

1
The Five Most Important Stories in Crypto This Week 18:58

1
The "Wave of Crazy New AI Stuff" Coming Next Month 22:24

1
How AI Is Already Changing Jobs 20:34

1
As eToro IPO Pops is Wall Street Getting Crypto Fever? 11:21

1
5 Questions Shaping the Near Future of Crypto and Macro 18:28

1
The Age of AI Diplomacy 18:27

1
What to Use Different AI Models For 22:21

1
Coinbase Joins the S&P 500 as Bitcoin and Traditional Finance Converge 10:06