Best James Mackey Podcasts (2025)

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#229 Outliers: Andy Grove – Only The Paranoid Survive 1:23:18

18m ago1:23:18

1:23:18

Most people protect their identity. Andy Grove would rewrite his, again and again. He started as a refugee, became a chemist, turned himself into an engineer, then a manager, and finally the CEO who built Intel into a global powerhouse. He didn’t cling to credentials or titles. When a challenge came up, he didn’t delegate, he learned. This episode …

1
#349 - AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity 11:25

12h ago11:25

11:25

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter dives deep into the topic of muscle mass and strength, examining their essential roles in both lifespan and healthspan. Drawing from over 30 hours of prior discussions wit…

1
#228 Elad Gil: How to Spot a Billion-Dollar Startup Before the Rest of the World 1:38:34

6d ago1:38:34

1:38:34

What if the world’s most connected tech investor handed you his mental playbook? Elad Gil, an investor behind Airbnb, Stripe, Coinbase and Anduril, flips conventional wisdom on its head and prioritizes market opportunities over founders. Elad decodes why innovation has clustered geographically throughout history, from Renaissance Florence to Silico…

1
EP 171: AI talent pipelines: Strategies for sustainable hiring in an era of rapid change with Lupe Colangelo, Director of Alumni Engagement & Employer Partnerships at General Assembly. 32:50

12d ago32:50

32:50

In this episode host James Mackey sits down with Lupe Colangelo, Director of Alumni Engagement & Employer Partnerships at General Assembly. They provide insights into the evolving tech talent landscape with a special focus on AI hiring trends and challenges faced by employers and job seekers alike. Lupe shares key findings from GA's State of Tech T…

1
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D. 2:13:28

7d ago2:13:28

2:13:28

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Rachel Rubin is a board-certified urologist and one of the nation's foremost experts in sexual health. In this episode, she shares her deep expertise on the often-overlooked topic of women’s sexual health, exploring wh…

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The Knowledge Project Podcast: Trailer 2:47

11d ago2:47

2:47

Trusted by Fortune 500 CEOs and elite performers, this is where you go to think better, live better, and get ahead. Each week, Shane Parrish goes deep with the world’s sharpest minds—founders, economists, bestselling authors—to uncover the mental models, habits, and strategies behind extraordinary results. The Knowledge Project isn't just a podcast…

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Hat Trick Hockey Talk - 2nd Round Playoff Show 44:06

14d ago44:06

44:06

The boys are back and this one is chaos.. Sean can't find a working dry erase marker, Ryan and Sean switch setups and James can't figure out how Streamyard works... The second round of the playoffs has begun and James won the first round, the boys make their second round predictions, Sean hates on Brandon Saad after game one of Vegas and Edmonton a…

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#227 Outliers: Rose Blumkin — Women of Berkshire Hathaway 45:58

13d ago45:58

45:58

Rose Blumkin didn’t just build a business. She revolutionized retail. After fleeing Russia with $66 in her purse, she opened a basement furniture store in Omaha at 43 years old—with no English, no education, and no connections. Her formula? Sell cheap, tell the truth, don't cheat the customer. Nebraska Furniture Mart would survive depressions, fire…

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#347 – Peter’s takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly ... 33:20

21d ago33:20

33:20

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from his discussions with Jeff English on…

1
Hat Trick Hockey Talk - First Round Playoff Show 43:38

22d ago43:38

43:38

The first round of the NHL Playoffs conclude on May 4th and the boys met just in time to talk about the first round matchups, the end of the season and make their selections for the remainder of the first round! Now apart of the Inside the Rink Podcast Network. Follow Us On Twitter: @HatTrickHkyTalk Follow Us On Instagram: @hattrickhockeytalk Follo…

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#226 Garry Tan: Billion-Dollar Misfits — Inside Y Combinator’s Startup Formula 2:23:14

20d ago2:23:14

2:23:14

Most accelerators fund ideas. Y Combinator funds founders—and transforms them. With a 1% acceptance rate and alumni behind 60% of the past decade’s unicorns, YC knows what separates the founders who break through from those who burn out. It's not the flashiest résumé or the boldest pitch but something President Garry Tan says is far rarer: earnestn…

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#346 - Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H. 2:05:50

21d ago2:05:50

2:05:50

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Susan Desmond-Hellmann is a physician and scientist whose remarkable career has spanned clinical medicine, oncology, biotech innovation, and global health leadership. In this episode, Susan shares insights from her jou…

1
EP 170: Georgetown's entrepreneurial ecosystem with Benjamin Zimmerman 36:13

25d ago36:13

36:13

Georgetown University is redefining entrepreneurial education by building a mission-driven ecosystem where innovation thrives. In this episode, our host, James Mackey, and Ben Zimmerman, Managing Director of Georgetown Entrepreneurship, share Georgetown’s unique approach to fostering an environment that helps startups succeed. From student programs…

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#225 Outliers: Henry Singleton – Distant Force 1:00:47

27d ago1:00:47

1:00:47

If Warren Buffett is the king of capital allocation—Henry Singleton is the ghost. Singleton built one of the most successful conglomerates in American history, transforming business while remaining virtually unknown. While Wall Street chased fads, Singleton, who could play chess blindfolded, quietly turned industrial conglomerate Teledyne into a bu…

1
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D. 2:47:06

28d ago2:47:06

2:47:06

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Sean Mackey is a professor of pain medicine at Stanford University and the director of the Stanford Systems Neuroscience and Pain Lab, where his research explores the neural mechanisms of pain and the development of no…

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EP 169: What’s Next for AI and Automation in Recruiting: Insights from Jason Heilman, Sr VP of Product, Automation, and AI at Bullhorn 36:30

1M ago36:30

36:30

Jason Heilman, Senior Vice President of Product, Automation, and AI at Bullhorn, and our host James Mackey, offer a masterclass in AI and Automation for recruiting organizations. Drawing from Jason’s experience as co-founder of Herefish (acquired by Bullhorn in 2019), Jason reveals how automation serves as the essential foundation for effective AI …

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#224 Bret Taylor: A Vision for AI’s Next Frontier 2:11:14

1M ago2:11:14

2:11:14

What happens when one of the most legendary minds in tech delves deep into the real workings of modern AI? A 2-hour long masterclass that you don’t want to miss. Bret Taylor, current chairman of OpenAI, unpacks why AI is transforming software engineering forever, how founders can survive acquisition (he’s done it twice), and why the true bottleneck…

1
#344 - AMA #70: Nicotine: impact on cognitive function, performance, and mood, health risks, delivery modalities, and smoking cessation strategies 21:47

1M ago21:47

21:47

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter dives deep into nicotine—a topic increasingly debated both scientifically and publicly. He clarifies the critical differences between nicotine and tobacco, highlighting wh…

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#223 Pierre Poilievre: What I Want to Build (and Break) To Fix Canada 1:23:27

1M ago1:23:27

1:23:27

Pierre Poilievre, leader of Canada’s Conservative Party, reveals a roadmap for restoring opportunity and unity across the country. From unleashing innovation by cutting red tape, to reigniting upward mobility and building a powerhouse economy, Poilievre’s message goes beyond borders. If you care about restoring opportunity, strengthening democracy,…

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#222 Outliers: Cornelius Vanderbilt — The First Tycoon 1:24:31

1M ago1:24:31

1:24:31

Cornelius Vanderbilt was a force in 19th century America, playing a pivotal role in transitioning the U.S. economy from rural mercantilism to industrial corporate capitalism. Vanderbilt didn't just compete—he dominated; and didn’t just dominate one industry—he conquered three: ferries, steamships, and railroads. He understood that power lay in cont…

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#343 – The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions | Sanjay Mehta, M.D. 2:12:12

2M ago2:12:12

2:12:12

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Sanjay Mehta is a radiation oncologist with over 25 years of experience, and is currently the president of Century Cancer Centers in Houston, Texas (drsanjaymehta.com). In this episode, Sanjay explores the rapidly evol…

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#221 Bruce Flatt on Value, Discipline, and Durability 1:20:54

2M ago1:20:54

1:20:54

Brookfield CEO Bruce Flatt reveals the investment philosophy behind building one of the world's largest alternative asset managers with over a trillion dollars under management. At the core of Brookfield's strategy is a disciplined focus on downside protection that has delivered 19% annualized returns over 30 years. Flatt identifies three major tre…

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EP 168: Navigating staffing in uncertain times: Insights from Hugo Malan, President of Kelly Science, Engineering, Technology & Telecom 35:37

2M ago35:37

35:37

In today’s unpredictable economy, businesses must navigate shifting market conditions while maintaining efficiency and resilience. Our host James Mackey and Hugo Malan, President of Kelly Science, Engineering, Technology, and Telecom, explore the power of a mixed labor strategy - a dynamic approach that blends full-time hires with temporary and pro…

1
#342 ‒ Aging well: Peter shares strategies for improving longevity with residents at a senior living center 43:33

2M ago43:33

43:33

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this special episode of The Drive, Peter joins a unique conversation inspired by his daughter’s volunteer experience at a senior care center, where she formed meaningful relationships with residents curious about he…

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#220 Outliers: James Dyson — Against the Odds 1:12:42

2M ago1:12:42

1:12:42

How do you turn 5,127 failures into a multi-billion-dollar empire? James Dyson turned dust into possibility, failure into discovery, and frustration into revolution. Dyson didn’t just build a better vacuum; he redefined a whole industry. Facing thousands of failed prototypes, crushing financial setbacks, and a dismissive industry that insisted a su…

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EP 167: Revolutionizing staffing through network intelligence with Brad Beach, CEO & Founder of Tailored Management & Jobvious 38:16

2M ago38:16

38:16

Join host James Mackey as he chats with Brad Beach, Founder and CEO of Tailored Management and Jobvious. Brad shares his journey from the early days in staffing to building a cutting-edge platform that’s reshaping contingent labor. They dive into the challenges of traditional hiring models, the power of network-driven recruitment, and how technolog…

1
#341 - Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D. 2:05:16

2M ago2:05:16

2:05:16

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Ashley Mason is a clinical psychologist and an associate professor at UCSF, where she leads the Sleep, Eating, and Affect (SEA) Laboratory. In this episode, Ashley provides a masterclass on cognitive behavioral therapy…

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#219 Logan Ury: The Dating Myths You Need to Stop Believing 2:12:51

2M ago2:12:51

2:12:51

Most people date the wrong way. They chase the spark, mistake attraction for compatibility, and expect their partners to read their minds. Then they wonder why relationships don’t last. Logan Ury thinks about dating differently. As the Director of Relationship Science at Hinge, she’s spent years studying what actually makes relationships work. Her …

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#340 - AMA #69: Scrutinizing supplements: creatine, fish oil, vitamin D, and more—a framework for understanding effectiveness, quality, and individual need 24:36

2M ago24:36

24:36

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores the complex world of supplements by introducing a practical framework for evaluating their effectiveness and relevance to individual health needs. Rather than pro…

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#218 Outliers: Estée Lauder — A Success Story 1:21:48

2M ago1:21:48

1:21:48

Most people hear "Estée Lauder" and think of cosmetics—lipstick, perfume, face cream. But the real story isn’t just about makeup—it’s about a woman being an unstoppable force. Estée Lauder didn’t just build a beauty brand; she rewrote the rules of an industry. She turned rejection into fuel, defied industry gatekeepers, and transformed a homemade f…

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Hat Trick Hockey - Trade Deadline Review Show 1:16:51

3M ago1:16:51

1:16:51

THE BOYS ARE BACK (kind of) FOR A TRADE DEADLINE REVIEW SHOW! Now apart of the Inside the Rink Podcast Network. Be sure to use code "ITR" on the Draft Kings Sportsbook App for up to $200 in bonus bets! Visit insidetherink.com/espn to sign up for ESPN+ and catch thousands of out of market games for this upcoming NHL season. Follow Us On Twitter: @Ha…

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#339 - Unpacking trauma: How early wounds shape behavior and the path toward healing | Jeff English 2:02:11

2M ago2:02:11

2:02:11

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Jeff English is a trauma-focused clinical counselor with extensive experience working with adults, teens, families, and groups across various settings, including career counseling, life coaching, addiction recovery, pr…

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EP 166: The Future of recruitment technology and automation for the Staffing and Recruiting industry with Sean Mallapurkar, CEO of Recruit CRM 34:40

2M ago34:40

34:40

Sean Mallapurkar joins host James Mackey to discuss the pivotal role technology is playing in shaping the future of staffing. Sean shares his remarkable journey from launching Recruit CRM to growing it into a global organization. Sean and James explore how recruitment professionals can benefit from integrating various technological solutions to str…

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#217 Josh Wolfe: Human Advantage in the World of AI 2:02:28

3M ago2:02:28

2:02:28

While Silicon Valley chases unicorns, Josh Wolfe hunts for something far more elusive: scientific breakthroughs that could change civilization. As co-founder and managing partner of Lux Capital, he's looking for the kind of science that turns impossible into inevitable. Josh doesn’t just invest in the future—he sees it coming before almost anyone e…

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#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4 27:41

3M ago27:41

27:41

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from his discussions on diverse topics su…

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#216 Outliers: Andrew Mellon – America’s Secret Banker 1:18:47

3M ago1:18:47

1:18:47

He was the strangest titan America ever produced: a whisper-quiet banker who turned systematic thinking into a superpower, building an industrial empire while barely raising his voice above a murmur. Andrew Mellon's story isn't just about money—it's about how patience, observation, and positioning can create more wealth than charisma ever could. Bu…

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