The researcher said that not all instances of Angler are using the new Flash zero-day exploit, nor is it being used against all of the popular browsers. In his tests, Kafeine found that IE 10 on Windows 8, IE 8 on Windows 7 and IE 6-9 on Windows XP all are being exploited. Chrome is not being targeted and fully patched Windows 8.1 is not exploitable, he said.
http://threatpost.com/exploit-for-flash-zero-day-appears-in-angler-exploit-kit/110569