Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Content provided by Stanford Engineering & Russ Altman and Stanford Engineering. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Stanford Engineering & Russ Altman and Stanford Engineering or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
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The future of Alzheimer’s treatment
Manage episode 455307983 series 2712286
Content provided by Stanford Engineering & Russ Altman and Stanford Engineering. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Stanford Engineering & Russ Altman and Stanford Engineering or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Guest Michael Greicius is an authority on Alzheimer’s disease. He makes the case that while effective treatments have remained elusive, there are high hopes for new approaches that target tau proteins in the brain associated with the disease. In the meantime, to reduce Alzheimer’s risk stay active, eat well, and manage circulatory risks, but skip genetic testing for now until better treatments emerge, Greicius tells host Russ Altman on this episode of Stanford Engineering’s The Future of Everything podcast.
Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to [email protected].
Episode Reference Links:
- Stanford Profile: Michael Greicius
Connect With Us:
- Episode Transcripts >>> The Future of Everything Website
- Connect with Russ >>> Threads / Bluesky / Mastodon
- Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook
Chapters:
(00:00:00) Introduction
Russ Altman introduces guest Michael Greicius, a professor of neurology and neurological sciences at Stanford University.
(00:02:12) Understanding Alzheimer's Disease
The roles of amyloid and tau proteins in Alzheimer's disease.
(00:04:53) Challenges in Developing Treatments
The multiple hurdles in creating Alzheimer's therapies.
(00:09:07) Current Alzheimer's Drugs
The controversies and limitations of recently approved drugs.
(00:10:23) Amyloid Plaques and Their Impact
Why removing amyloid plaques hasn’t improved patient outcomes.
(00:14:29) Problems with Alzheimer's Trials
The disconnect between amyloid removal and patient outcomes.
(00:18:03) Functional Unblinding and Trial Bias
How functional unblinding affects trial results and drug evaluations.
(00:23:51) The Potential of Targeting Tau
New breakthroughs in targeting tau protein for Alzheimer’s.
(00:26:35) The Future of Prevention
Potential preemptive treatments for Alzheimer's and their administration.
(00:29:19) Lifestyle and Risk Reduction
Recommendations for reducing risk of Alzheimer’s disease.
(00:31:43) Conclusion
Connect With Us:
Episode Transcripts >>> The Future of Everything Website
Connect with Russ >>> Threads / Bluesky / Mastodon
Connect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
340 episodes
Share
Manage episode 455307983 series 2712286
Content provided by Stanford Engineering & Russ Altman and Stanford Engineering. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Stanford Engineering & Russ Altman and Stanford Engineering or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Guest Michael Greicius is an authority on Alzheimer’s disease. He makes the case that while effective treatments have remained elusive, there are high hopes for new approaches that target tau proteins in the brain associated with the disease. In the meantime, to reduce Alzheimer’s risk stay active, eat well, and manage circulatory risks, but skip genetic testing for now until better treatments emerge, Greicius tells host Russ Altman on this episode of Stanford Engineering’s The Future of Everything podcast.
Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to [email protected].
Episode Reference Links:
- Stanford Profile: Michael Greicius
Connect With Us:
- Episode Transcripts >>> The Future of Everything Website
- Connect with Russ >>> Threads / Bluesky / Mastodon
- Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook
Chapters:
(00:00:00) Introduction
Russ Altman introduces guest Michael Greicius, a professor of neurology and neurological sciences at Stanford University.
(00:02:12) Understanding Alzheimer's Disease
The roles of amyloid and tau proteins in Alzheimer's disease.
(00:04:53) Challenges in Developing Treatments
The multiple hurdles in creating Alzheimer's therapies.
(00:09:07) Current Alzheimer's Drugs
The controversies and limitations of recently approved drugs.
(00:10:23) Amyloid Plaques and Their Impact
Why removing amyloid plaques hasn’t improved patient outcomes.
(00:14:29) Problems with Alzheimer's Trials
The disconnect between amyloid removal and patient outcomes.
(00:18:03) Functional Unblinding and Trial Bias
How functional unblinding affects trial results and drug evaluations.
(00:23:51) The Potential of Targeting Tau
New breakthroughs in targeting tau protein for Alzheimer’s.
(00:26:35) The Future of Prevention
Potential preemptive treatments for Alzheimer's and their administration.
(00:29:19) Lifestyle and Risk Reduction
Recommendations for reducing risk of Alzheimer’s disease.
(00:31:43) Conclusion
Connect With Us:
Episode Transcripts >>> The Future of Everything Website
Connect with Russ >>> Threads / Bluesky / Mastodon
Connect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
340 episodes
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Similar to The Future of Everything
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
…
continue reading
We humans could have a bright future ahead of us that lasts billions of years. But we have to survive the next 200 years first. Join Josh Clark of Stuff You Should Know for a 10-episode deep dive that explores the future of humanity and finds dangers we have never encountered before lurking just ahead. And if we humans are alone in the universe, if we don't survive intelligent life dies out with us too.
…
continue reading
Whether we wear a lab coat or haven't seen a test tube since grade school, science is shaping all of our lives. And that means we all have science stories to tell. Every year, we host dozens of live shows all over the country, featuring all kinds of storytellers - researchers, doctors, and engineers of course, but also patients, poets, comedians, cops, and more. Some of our stories are heartbreaking, others are hilarious, but they're all true and all very personal. Welcome to The Story Collider!
…
continue reading
The Science Show gives Australians unique insights into the latest scientific research and debate, from the physics of cricket to prime ministerial biorhythms.
…
continue reading
The kickass science and technology radio show that delivers an irreverent look at the week in science and technology.
…
continue reading
Best Business Podcast (Gold), British Podcast Awards 2023 How do you build a fully electric motorcycle with no compromises on performance? How can we truly experience what the virtual world feels like? What does it take to design the first commercially available flying car? And how do you build a lightsaber? These are some of the questions this podcast answers as we share the moments where digital transforms physical, and meet the brilliant minds behind some of the most innovative products a ...
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continue reading
The Naked Scientists flagship science show brings you a lighthearted look at the latest scientific breakthroughs, interviews with the world's top scientists, answers to your science questions and science experiments to try at home.
…
continue reading
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