In this conversation, Dr. Karen Radley discusses the GLP-1 drugs, their mechanisms, patient selection, risks, and alternatives for weight loss. She emphasizes the importance of understanding the side effects and the long-term implications of using these medications, while also highlighting the need for a holistic approach to weight management that includes diet and exercise.

Takeaways

GLP-1 drugs are primarily used for diabetes and obesity.

They stimulate insulin production and reduce appetite.

Weight loss effects can lead to off-label use in non-diabetic patients.

Patients with a BMI over 30 or comorbidities may benefit most.

Side effects include gastrointestinal issues and potential long-term risks.

Many patients stop using GLP-1 drugs due to side effects.

Weight regain is common after discontinuation of GLP-1 medications.

Diet and exercise remain crucial for sustainable weight loss.

Accountability in weight management programs enhances success.

Societal factors contribute to the obesity crisis, including diet change