Best What If It S Cool Podcasts (2025)

1
Trump wants to put humans on Mars: what scientists think of the plan 11:47

35m ago11:47

11:47

In this Podcast Extra, we examine President Donald Trump's calls for NASA to land humans on Mars. Although the White House has proposed spending some US$1 billion in 2026 on Mars plans, critics say the final cost will likely be hundreds of billions of dollars spread over a number of years. This call comes amidst plans to drastically reduce NASA's f…

1
Should You Run Your Marketing Team From Home Or From An Office?, Stop Trying To Measure Everything, A/B Testing At Its Finest, Google Lens Coming To YouTube Shorts 18:40

2d ago18:40

18:40

In this episode #2983, Eric Siu and Neil Patel discuss handling negative feedback on social media, the shift in remote work dynamics, and how AI is reshaping workforce structures. They highlight the engagement value of negative headlines and explore innovations in commerce through tools like Google Lens and YouTube Shorts. The conversation undersco…

1
Pharma’s New Game: The 279th Evolutionary Lens with Bret Weinstein and Heather Heying 2:04:53

34m ago2:04:53

2:04:53

Many topics today! First: FDA tentatively approves Moderna’s new mRNA shot for Covid. What? And also why? Bret has six main points, which include discussion of mucosal immunity, IgG4, auto-immunity, long-term consequences, statistical tricks, and homeopathy. Then: how do we know what is true, and how can we avoid jumping to conclusions when trigger…

1
Male mice can grow female organs — if their mothers lack iron 30:08

1h ago30:08

30:08

00:45 Iron’s role in mice sex determination Iron deficiency in mice mothers can sometimes result in their offspring developing female sex organs despite having male sex genes, according to new research. While genetics has been thought to be the primary factor in determining offspring sex in mammals, the new work shows that a lack of iron disrupts a…

1
How We Keep A Positive Mindset When Things Are Rocky Economically, AI Has Killed Informational Content For SEO 28:28

3d ago28:28

28:28

In this episode #2982, Eric Siu and Neil Patel discuss maintaining a positive mindset during economic challenges, emphasizing resilience, perspective, and adding value to others. They explore the shift in content marketing strategies driven by AI, stressing the need for original, value-driven content that resonates with the ideal customer. The conv…

1
When Marketing Can Go Wrong: Taco Bell Adds Quality Meats To Its Creative Roster, How We Are Going To Test Using AI On Our Marketing Qualified Leads 18:57

4d ago18:57

18:57

In this episode #2981, Eric Siu and Neil Patel discuss when marketing goes wrong, using Taco Bell’s quality meat announcement as an example, and contrast it with effective strategies that drive positive results. They highlight the role of AI in generating marketing qualified leads, the power of consistent follow-ups, and the value of authenticity a…

1
What I Learned By Talking To A Marketing Team About AI At A Company That Generates Over 20 Billion A Year, SEOs Are Getting Fired Left And Right 29:03

5d ago29:03

29:03

In this episode #2981, Eric Siu and Neil Patel discuss the challenges and opportunities of AI in marketing, highlighting the gap between AI adoption and actual business results. They explore the future of SEO, the importance of accountability in AI usage, and the need for consistent brand engagement. The conversation also emphasizes collaboration o…

1
Wisdom of the Ancients: Dr. Robert Clancy on DarkHorse 1:09:14

4d ago1:09:14

1:09:14

Bret Weinstein speaks with Emeritus Professor Robert Clancy AM on the subject of mucosal immunology. Find Dr. Clancy at The University of New Castle Australia: https://www.newcastle.edu.au/profile/robert-clancy ***** Sponsors: Dose for your Liver: Tasty drink with milk thistle, ginger, dandelion & turmeric to support liver health. Save 30% of your …

1
Audio long read: Three ways to cool Earth by pulling carbon from the sky 15:59

4d ago15:59

15:59

With the world looking likely to blow past the temperature targets laid out in the 2015 Paris climate agreement, a growing number of voices are saying that carbon removal technologies will be necessary if humanity is to achieve its long-term climate goals. If these approaches succeed, they could help nations and corporations to meet their climate c…

1
Cool S**t We're Doing In AI This Quarter, How This Weird Economy Is Affecting Marketing, How We're Generating Pipeline In A Weird Economy 24:27

10d ago24:27

24:27

In this episode #2980, Eric Siu and Neil Patel discuss how AI is revolutionizing advertising, the evolution of digital marketing strategies, and shifting workplace dynamics. They also reflect on the trade-offs between fame and anonymity in today’s digital world. TIME-STAMPED SHOW NOTES (00:00) Revolutionizing Advertising with AI (02:55) The Evoluti…

1
The Real Matrix: The 278th Evolutionary Lens with Bret Weinstein and Heather Heying 1:40:27

6d ago1:40:27

1:40:27

We begin with the HHS announcement that Covid shots will no longer be recommended to healthy children and pregnant women. What does healthy mean? And what are the conditions that provide release from liability for vaccine makers? Then, a discussion of kinds of immunity, and how vaccines are best delivered depending on how disease is transmitted. We…

1
AI linked to boom in biomedical papers, infrared contact lenses, and is Earth's core leaking? 20:11

7d ago20:11

20:11

00:33 Was a boom in papers driven by AI? A spike in papers formulaically analysing a public data set has sparked worries that AI is being used to generate low quality and potentially misleading analyses. Nature: AI linked to explosion of low-quality biomedical research papers 08:07 Lenses that give humans infrared vision Researchers in China have c…

1
How Netflix Is Revolutionizing Ad Buying, Bosses Are Done Being 'Nice’, 14M YouTuber Quits - Is Going Viral Worth It? 18:03

11d ago18:03

18:03

In this episode #2979, Eric Siu and Neil Patel discuss how AI is transforming advertising, including Netflix's dynamic ad placements. They explore shifts in digital marketing, evolving workplace expectations, and the balance between fame and anonymity in the digital age. TIME-STAMPED SHOW NOTES (00:00) Revolutionizing Advertising with AI (02:55) Th…

1
The Mucus Mystery: Dr. Lon Jones, DO on DarkHorse 1:08:00

7d ago1:08:00

1:08:00

Bret speaks with Dr. Lon Jones, DO on the subject of the mismatch between modern humans and the environment they live in. Find Dr. Lon Jones, DO at https://commonsensemedicine.org ***** Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse…

1
SEO Attribution Is COMPLETELY F**CKED, Dressing Nice Doesn't Make You More Money, How To Get A 50% Discount On Luxury Clothes 24:50

12d ago24:50

24:50

In this episode #2978, Eric Siu and Neil Patel discuss the challenges of SEO attribution, the evolution of marketing, and the need to prioritize customer value over metrics. They also explore the role of personal branding, appearance, and the psychology of giving in business success. TIME-STAMPED SHOW NOTES (00:00) The Challenge of SEO Attribution …

1
Why I Fired My $25k/mo YouTube Agency, The Business Case for AI Mode, Website Traffic Is Toast (The Rapid Decline) 36:02

13d ago36:02

36:02

In this episode #2977, Eric Siu and Neil Patel discuss Neil’s experience with a YouTube agency, emphasizing the importance of strong scripts and the challenges with communication. They share insights on managing video content, the shifting impact of SEO and AI, and adapting to changes in website traffic and attribution. TIME-STAMPED SHOW NOTES (00:…

1
Are Standing 1 On 1's Stupid?, Erewhon's Sneaky Way To Bring Customers Back, He Sends Custom Swords To Get Millions In Profits (100% Response Rate), How We're Going To Ramp The F**K Out Of YouTube 24:17

17d ago24:17

24:17

In this episode #2976, Eric Siu and Neil Patel explore one-on-ones, marketing tactics, economic trends, and how politics and consumer behavior impact business. They also share YouTube growth tips and creative strategies. TIME-STAMPED SHOW NOTES (00:00) The Value of Standing One-on-Ones (02:53) Marketing Strategies and Consumer Behavior (05:53) Econ…

1
Occam’s Sledgehammer: The 277th Evolutionary Lens with Bret Weinstein and Heather Heying 1:43:03

13d ago1:43:03

1:43:03

It’s Prostate Week in Podcastistan: what happens when an MRI scan for prostatitis includes the injection of rare earth metals—should you, or shouldn’t you? Gadolinium crosses the blood-brain barrier if the barrier is not fully intact—does that affect your decision? Then: a letter from an MD-PhD student at Harvard prompts musings on the federal fund…

1
These malaria drugs treat the mosquitos — not the people 31:40

13d ago31:40

31:40

00:45 Treating mosquitoes for malaria Researchers have developed two compounds that can kill malaria-causing parasites within mosquitoes, an approach they hope could help reduce transmission of the disease. The team showed that these compounds can be embedded into the plastics used to make bed nets, providing an alternative to insecticide-based mal…

1
The Management Styles Of Mark Zuckerberg And Jensen Huang, Private CEO Conversations Around AI And Their People, The Real Use Case For AI (It's Not Replacing Jobs) 26:56

18d ago26:56

26:56

In this episode #2975, Eric Siu and Neil Patel explore how tech giants are driving innovation and how AI is reshaping jobs, marketing, and workplace culture. They highlight the importance of adapting to constant change. TIME-STAMPED SHOW NOTES (00:00) Tech Giants and Innovation Trends (02:51) AI's Impact on Employment and Corporate Strategy (05:53)…

1
Anarchism Cataclysm: Michael Malice on DarkHorse 1:49:15

14d ago1:49:15

1:49:15

Bret speaks with Michael Malice about the vaccine injured, the importance of continuing to seek answers about what happened during COVID, and the topic of anarchism. Find Michael Malice on X at https://x.com/michaelmalice ***** Sponsors: Helix: Excellent, sleep-enhancing, American-made mattresses. Go to http://www.HelixSleep.com/DarkHorse for 27% O…

1
The One Trait That Determines If You'll Be Rich, The One Thing Worth Micromanaging On Forever, How Bad Is The Economy Affecting Marketing? 30:39

18d ago30:39

30:39

In this episode #2974, Eric Siu and Neil Patel discuss staying resilient in tough times, balancing ethics in business, and the role of tech in preserving memories and legacies. They also reflect on how AI might shape personal brands. TIME-STAMPED SHOW NOTES (00:00) Resilience in Business Challenges (02:51) Navigating Financial Strains and Investmen…

1
AI Is Going To Revolutionize Marketing, How To Instantly Get The Best AI Prompts 21:01

19d ago21:01

21:01

In this episode #2973, Eric Siu and Neil Patel explore how AI is reshaping marketing, focusing on organizational changes, email strategies, and content creation. They talk about finding the right mix between using AI tools and keeping the human touch. TIME-STAMPED SHOW NOTES (00:00) The Impact of AI on Marketing Organizations (03:05) AI in Email Ma…

1
Does Being Transparent Really Help In Your Marketing?, First Principles Of Generational Businesses, What We Learned From A Private Conference Ratings, Why Our YouTube Channels Are Starting To Finally ... 28:21

24d ago28:21

28:21

In episode #2972, Eric Siu and Neil Patel discuss the power of transparency in marketing and the core principles of building a generational business. They highlight the importance of customer feedback, strong teams, and retention, while also exploring the evolution of content creation and lessons from business challenges. TIME-STAMPED SHOW NOTES (0…

1
How to transport antimatter — stick it on the back of a van 30:31

20d ago30:31

30:31

00:46 An antimatter delivery van takes its first road trip Researchers have developed a portable antimatter containment device and tested it by putting it in a truck and driving it around CERN. Their system could represent a big step forward in efforts to take particles made at CERN’s ‘antimatter factory’ and transport them to other labs, something…

1
How To Create Data Discipline In Your Organization, Why Freemium Doesn't Work As Well Anymore, Marketing Today Vs Marketing Tomorrow, How AI Helps Create 'New Work' That Was Previously Impossible, Anti ... 27:02

25d ago27:02

27:02

In episode #2971, Eric Siu and Neil Patel discuss building a data-driven culture, stressing the importance of relevant data and adaptability in marketing. They explore how AI is reshaping marketing by increasing speed and efficiency, and examine the challenges of freemium models and surprising campaign outcomes. TIME-STAMPED SHOW NOTES (00:00) Cult…

1
Report from the Foxhole: The 276th Evolutionary Lens with Bret Weinstein and Heather Heying 1:59:54

21d ago1:59:54

1:59:54

What happens when we commodify nature? The natural world is not doing well, and is not put here to do with as we want. How can we learn to appreciate nature, and environment, without jumping to conclusions about what is happening, or picking sides in an ideological battle that has nothing to do with actual wild nature? Also: how are DOGE cuts affec…

1
The Power Of Brand, Why I'm Shifting My Marketing Strategy To FREE Over Content Creation 22:05

26d ago22:05

22:05

In episode #2970, Eric Siu and Neil Patel discuss how AI is changing search engines, the role of natural conversations in content, and smart lead generation tactics. They also explore freemium models for engagement, share thoughts on balancing work and family, and highlight innovative marketing strategies for growth. TIME-STAMPED SHOW NOTES (00:00)…

1
NSF terminates huge number of grants and stops awarding new ones 11:15

22d ago11:15

11:15

In this Podcast Extra, we examine recent developments US National Science Foundation, which has seen significant numbers of research grants terminated. In addition, there have been freezes on funding for new grants and any additional money to existing ones. We also discuss US President Donald Trump’s proposed budget for fiscal year 2026, which call…

1
Cloudflare CEO: AI Is Killing The Business Model Of The Web, SEO On Safari Has Dropped For The First Time In 22 Years Because..., Are SEOs F**cked? 23:19

27d ago23:19

23:19

In episode #2969, Eric Siu and Neil Patel discuss how AI is reshaping business models and digital marketing. They examine shifts in search behavior, the decline in website traffic, and the rise of platform dominance. The episode also highlights Google’s challenges and the need for marketers to innovate and adapt. TIME-STAMPED SHOW NOTES (00:00) The…

1
By Any Means Necessary? The 275th Evolutionary Lens with Bret Weinstein and Heather Heying 1:17:33

26d ago1:17:33

1:17:33

Is MAHA under threat? If so, what is the nature of the threat? Following the nomination of Casey Means for Surgeon General, MAHA on-line has polarized: is she a Manchurian candidate, or is she what she appears? If she is what she appears, is her lack of focus on vaccine safety cause for concern? What is the value of experience, clinical and otherwi…

1
The New Startup Playbook, CEOs Are Choosing More AI. Less Jobs. 18:57

1M ago18:57

18:57

In episode #2968, Eric Siu and Neil Patel discuss the new startup playbook, questioning the need for traditional venture capital and emphasizing AI’s growing role. They highlight the shift toward selling outcomes over software, the impact of AI on jobs, and the importance of lifelong learning over passive career paths. Note: This episode is recorde…

1
Herring population loses migration 'memory' after heavy fishing 37:34

27d ago37:34

37:34

00:46 How fishing activity altered the migration pattern of Herring Selective fishing of older herring has resulted in a large shift in the migration pattern of these fish, according to new research. For years, herring have visited sites on the south coast of Norway to spawn, but in 2020 a rapid shift was seen, with the fish instead visiting areas …

1
How To Get The Best Speakers For Your Events (For Free), Are TikTokers Really Broke?, What I Learned From Hosting A Private Summit With 185 Business Operators, They Raised $25M And Spent $12M On A Domain ... 28:36

1M ago28:36

28:36

In episode #2967, Eric Siu and Neil Patel discuss building relationships to attract top event speakers, share marketing insights from a private summit, and examine TikTok advertising. They highlight the value of authenticity in events, the impact of domain name investments, and the importance of AI, high agency, and distribution in driving success.…

1
60% Of Traditional Searches Don't End With A Click Now, The One Common Thing With The Best Marketers In The World, How To Generate The Most Revenue From Conferences, How To Manifest 7-Figure Deals From ... 24:54

1M ago24:54

24:54

In episode #2966, Eric Siu and Neil Patel discuss the shift to zero click results and the growing importance of strong branding in digital marketing. They cover strategies for mastering marketing channels, increasing conference revenue, and building lasting business relationships. The episode offers insights on adapting to today’s complex marketing…

1
How Long It Really Takes To Win A Deal in 2025, Why You Have To Diversify Your Marketing, The 'One-Click' Future of Marketing, Is Black Hat Seo Back for AI?, Is GEO actually different from SEO? 26:48

1M ago26:48

26:48

In episode #2965, Eric Siu and Neil Patel discuss the intricacies of sales cycles, particularly in the context of conferences, emphasizing the importance of consistent follow-up. They explore how AI is shaping marketing trends, the promise of one-click marketing, and the risks of black hat SEO, stressing the value of long-term strategy. The episode…

1
It Really Does Take 10 Years To Build A Brand, Are Most CEOs On A Rampage Right Now?, Shopify Is Making E-Commerce Sites A Relic? 22:19

1M ago22:19

22:19

In episode #2964, Eric Siu and Neil Patel discuss the value of events for networking, balancing work and family, and how CEOs adapt during tough times. They share travel experiences, reflect on leadership cycles, and explore the future of e-commerce and websites. Note: This episode was recorded while traveling. Audio quality may be lower than our u…

1
Misinformed Consent: The 274th Evolutionary Lens with Bret Weinstein and Heather Heying 1:53:35

1M ago1:53:35

1:53:35

What’s in our medicines? There are active ingredients, and there are excipients, which is everything else. From colorants to emulsifiers to adjuvants, excipients hide many horrors, and it’s not even possible to know which ones are in your meds (or foods). Dairy that has been fortified with vitamins A & D also has seed oils and emulsifiers, but thos…

1
The dismantling of US science: can it survive Trump 2.0? 27:52

1M ago27:52

27:52

In this episode: 00:46 What will be left of US science after Trump 2.0? 100 days into his term, President Donald Trump and his administration have already caused the biggest shakeup in modern scientific history, slashing funding, bringing large swathes of US research to a standstill and halting many clinical trials. But many fear these actions are …

1
Apple Rebrands Search Ads As Apple Ads, Why We are Integrating QR Codes In Our Marketing Content, Why Being CEO Is The Worst Job 20:50

1M ago20:50

20:50

In episode #2963, Eric Siu and Neil Patel discuss Apple's shift to ads, the effectiveness of QR codes, and the challenges CEOs face. They also cover navigating business challenges and the cyclical nature of business resilience. Note: This episode was recorded while traveling. Audio quality may be lower than our usual standards. TIME-STAMPED SHOW NO…

1
How We Buy Attention, Why I Never Try To Go For Multi-Million Dollar Deals, CEOs Are Choosing More AI, Less Jobs 27:23

1M ago27:23

27:23

In episode #2962, Eric Siu and Neil Patel discuss buying attention in digital marketing, the evolution of personal branding, and the growing role of AI. They highlight the risks of algorithm changes and the need to combine human insight with AI to drive business efficiencies. Note: This episode was recorded while traveling. Audio quality may be low…

Podcasts Worth a Listen

What If It S Cool Podcasts

Podcasts Worth a Listen