The Bio Accelerationism (bio/acc) podcast. Deeply researched interviews about fascinating topics from biotech and research. Podcast hosted by Shriya Bhat, a Harvard Sophomore from the Harvard Bioethics Communication Initiative (BCI).
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Shriya Bhat Podcasts
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Germline Editing Could Cost Less Than IVF — Cathy Tie
41:03
41:03
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In this episode, biotech founder Cathy Tie unpacks the realities of building in regulated industries and the promise of gene editing done right. From unicorns and dragons to disease-free babies, we explore the technical, ethical, and economic future of germline correction.Check out the Manhattan Project: https://manhattangenomics.com/ 0:00 Intro 1:…
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Longevity Escape Velocity May Be Closer Than We Think — Aubrey de Grey and Benji Leibowitz
1:10:45
1:10:45
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1:10:45
In this episode, I sit down with Aubrey de Grey, one of the leading voices in longevity science, and Benji Leibowitz, founder of Pump Science, to explore two visions of the future: longevity escape velocity and scientific escape velocity. We dive into the biology of aging, the systemic bottlenecks slowing progress, and bold new ideas for accelerati…
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Is the Longevity Field Overhyped? Charles Brenner—NAD Metabolomics Pioneer and Aging Realist
49:05
49:05
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49:05
In this episode, I talk to Charles Brenner, a leading biochemist and outspoken critic of hype in the longevity field. We discuss why many aging studies in model organisms don’t always translate to humans, the limitations of current NAD-related therapies, and how publication bias harms scientific progress. He also shares what excites him most right …
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The Future of Biotech Won’t Be Funded by VCs — YC Founder James Sinka
1:13:15
1:13:15
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1:13:15
In this episode, I talk to James Sinka, a YC 3-time founder who believes that biotech on-chain will be the next revolution in funding for academic projects. We discuss the challenges of being a deep-tech founder, the intersection of AI & medicine, and some of the key lessons founders need to learn along the way.…
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YC Biotech Founder Wants to End All Rare Disease - Ethan Perlstein (Ep. 11)
38:32
38:32
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38:32
In this episode, I talk to Ethan Perlstein, a YC biotech founder who wants to make better drugs and financial incentives for curing rare diseases. We discuss the post-academic collapse in science careers, the financial abandonment of most rare diseases, and how crypto and AI could revolutionize drug development.…
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The Ethics of Human Germline Editing with Francoise Baylis
44:26
44:26
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44:26
In this episode, I speak with Professor Francoise Baylis, a renowned Canadian bioethicist whose work lies at the intersection of applied ethics, health policy, and practice. We talk about the ethics of research on human embryos -- at what date the line should be drawn -- and whether it practically and morally makes sense to allow for human germline…
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George Church -- The Godfather of Synthetic Biology, CRISPR, and De-Extinction (Ep. 10)
40:06
40:06
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40:06
In this episode, I speak with George Church—pioneer of human genome sequencing, co-inventor of CRISPR, and founder of over 50 biotech startups—on the future of synthetic biology: virus-proof cells, multiplex gene editing, and what it takes to reverse aging. We talk Ginkgo’s trajectory, 23andMe’s missed opportunity, and why the next bio revolution w…
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The Mind-Bending Science of Staying Alive -- Carl Zimmer on Aging, AGI, and Brain Organoids (Ep. 9)
30:39
30:39
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30:39
In this episode, I speak with award-winning NYT science writer Carl Zimmer (“Life’s Edge”, “She Has Her Mother’s Laugh”) on the verbs of biology—homeostasis, life being organized rebellion against entropy, and whether brain organoids might wake up while we’re not looking.
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Jamie Metzl - Will Humanity Survive Gene Editing and AI? (Ep. 8)
44:22
44:22
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44:22
In this episode, I talk with Jamie Metzl — geopolitical futurist, former WHO advisor, and author of Superconvergence — about the future of gene editing, AGI, and the existential risks no one is talking about. We cover CRISPR will rewrite evolution and society, and why AGI is a myth (and what we're really building).…
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Aubrey de Grey on Immortality, Longevity Research, and How to Live for 200 Years (Ep. 7)
51:35
51:35
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51:35
In this episode, I talk with Dr. Aubrey de Grey, a leading researcher in the longevity space and co-founder of the SENS Research Foundation, known for his groundbreaking work in developing therapies that reverse DNA damage at the cellular level. We talk about the latest breakthroughs in aging science, what aging research looks like in a post-AGI wo…
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Robert Langer: Founding Moderna and Publishing Over 1500 Research Papers (Ep. 6)
34:17
34:17
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34:17
In this episode, I talk with Dr. Robert Langer, co-founder of Moderna and PI of the world’s largest biomedical engineering lab at MIT. We talk about his background, how to raise money for biotech ventures, and whether innovation can be born from the lab.
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The Man Who Used Gene Editing On Babies - He Jiankui (Ep. 5)
30:17
30:17
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30:17
In this episode, I talk with Dr. He Jiankui, a gene editing pioneer who used CRISPR/Cas technology to edit the infamous twin babies Lulu and Nana. We talk about his goals, ethics behind the technology, and the potential for a utopian and dystopian future.
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Immune-Based Therapies with Dr. Victor Nizet (Ep. 4)
47:50
47:50
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Dr. Victor Nizet, Professor of Pediatrics and Vice Chair for Basic Research at UC San Diego details some of the innovative approaches being used in his lab to fight infectious disease, namely, host-targeted immune based therapies. We discuss many of the major problems in infectious disease, including antibiotic resistance, novel drug mechanisms, an…
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Antimicrobial Resistance with Dr. Carl Nathan (Ep. 3)
38:18
38:18
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38:18
Dr. Nathan, a leading expert in microbiology and immunology, summarizes one of the most pressing problems in medicine: antimicrobial resistance. We discuss the evolution of drug resistance pathogens as well as the scientific, public health, and business frameworks that govern this problem. We finally discuss how the UN can come together to build et…
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Vaccines with Dr. Stanley Plotkin, "Godfather of Vaccines" (Ep. 2)
31:06
31:06
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31:06
Dr. Stanley Plotkin is often hailed as the ‘Godfather of Vaccines.’ His pioneering work has not only led to the development of the rubella vaccine—critical in eradicating rubella across the Americas—but also propelled breakthroughs in vaccines for rabies, polio, and anthrax. We discuss breakthroughs in vaccine development, reducing public skepticis…
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Antimicrobial Stewardship with Dr. Alberto Giubilini (Ep. 1)
22:39
22:39
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22:39
Dr. Alberto Giubilini, a philosopher and leading expert in bioethics, introduces one of the most pressing issues in public health: antibiotic overuse. We discuss how unchecked consumption of these life-saving drugs can lead to a “tragedy of the commons,” why some experts are calling for an antibiotic tax, and the broader ethica…
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