Best Proof Beyond Reason Podcasts (2025)

1
Future-Proofing the UK Life Sciences Sector 17:17

9h ago17:17

17:17

Are you prepared for the seismic shift transforming UK life sciences careers? This latest "In Silico Trials, Real Impacts!" episode reveals how AI and in silico technologies are creating unprecedented employment opportunities across health tech sectors. Discover the essential skills driving this revolution, from computational biology to digital the…

1
AI in Manufacturing and Compliance with Chief Innovation Officer, Kristina Kristina Hloptsidis, of Signify 40:17

3h ago40:17

40:17

In this conversation, Kristina Hloptsidis, Chief Innovation Officer at Signify, discusses the challenges of compliance management in heavily regulated industries, particularly manufacturing, with Dr. Joan Palmiter Bajorek. She emphasizes the role of AI in transforming compliance processes, making them more efficient and strategic. Sound Bites "Regu…

1
Cathie Wood - Inside ARK Invest's Big Ideas Report Episode 2 - Bitcoin, Stablecoins, Scaling Blockains, Robotaxis 25:17

3h ago25:17

25:17

ARK Invest Big Ideas 2025: Convergence of Innovation This briefing document summarizes the key themes and important insights from ARK Investment Management LLC's "Big Ideas 2025: Convergence" report, published on February 4, 2025. The report highlights significant technological advancements and their potential to disrupt various industries and crea…

1
Cathie Wood - AI & Convergence: Inside ARK Invest’s Big Ideas Report Ep. 1 37:06

15h ago37:06

37:06

CEO AI PODcast | Ep. 1 – Artificial Intelligence & Convergence: Inside ARK Invest’s Big Ideas Report We kick off our 3-part series with a bold look into Cathie Wood's ARK Invest’s Big Ideas 2025 - a much anticipated and awaited compendium by Cathie and ARK's hotshot analysts on where the opportunity are in Artificial Intelligence. In this episode: …

1
The Narrow Path: Sam Hammond on AI, Institutions, and the Fragile Future 47:55

7d ago47:55

47:55

The race to develop ever-more-powerful AI is creating an unstable dynamic. It could lead us toward either dystopian centralized control or uncontrollable chaos. But there's a third option: a narrow path where technological power is matched with responsibility at every step. Sam Hammond is the chief economist at the Foundation for American Innovatio…

1
The Illusion of Reasoning - A discussion of Apple's WWDC Blockbuster Whitepaper 10:36

3d ago10:36

10:36

Apple just blew the lid off of reasoning models by demonstrating that they break down and become highly inaccurate for many classes of complex problems. A must listen if you are applying AI to your business in any way ! Dive into the controversial limitations of cutting-edge AI! This episode explores groundbreaking research, including contributions…

1
Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard 32:52

5d ago32:52

32:52

Are Randomised Controlled Trials (RCTs) always the definitive 'gold standard' in research? In the latest episode of In Silico Trials, Real Impacts!, we explore the nuanced landscape of RCTs, questioning their universal applicability and examining the complexities they often obscure. While RCTs are celebrated for their rigour, this discussion delves…

1
To the Graduating Class of 2025: Real Talk Career Advice for High School and College Grads 18:45

6d ago18:45

18:45

What's strong advice for graduates in 2025? [Audio fixed! Thank you to our devoted listeners for letting us know about the echo issue on the first upload! :D] Worried about careers in the age of AI? What advice would you give graduates about to embark on modern careers? In this episode, Dr. Joan Palmiter Bajorek discusses career paths for high scho…

1
Mary Meeker/ BOND AI Trends Report - Summary Overview 6:02

9d ago6:02

6:02

This report sets out to compile foundational trends related to Artificial Intelligence. One of the key takeaways is the unprecedented rate at which the world is changing due to rapid and transformative technology innovation and adoption, particularly in AI. The pace of change seems faster than ever, and AI User, Usage, and Capital Expenditure Growt…

1
Mary Meeker/BOND AI Report - Comprehensive Version 41:09

9d ago41:09

41:09

This report sets out to compile foundational trends related to Artificial Intelligence. One of the key takeaways is the unprecedented rate at which the world is changing due to rapid and transformative technology innovation and adoption, particularly in AI. The pace of change seems faster than ever, and AI User, Usage, and Capital Expenditure Growt…

1
Book Summary - Empire of AI: The Tension Between Ideals and Reality by Karen Hao 4:31

10d ago4:31

4:31

In this episode, we explore the insightful book "Empire of AI: Dreams and Nightmares in Sam Altman's Open AI" by Karen Hau. This book examines the internal conflicts within OpenAI, highlighting the tension between its original mission for AGI safety and its current commercial ambitions. We discuss how OpenAI's transformation from a non-profit to a …

1
"The Art of Bouncing Back: Lessons from Coach Dar" 19:02

11d ago19:02

19:02

Welcome to the CEO AI Podcast, where today's discussion focuses on resilience and how setbacks can become the driving force for success, especially in the AI-driven business world. We explore "The Art of Bouncing Back," authored by Darlene Santor, also known as Coach Dar. Coach Dar leverages her extensive experience as an occupational therapist and…

1
Simpler or Complex: Rethinking Occam's Razor in Modelling Science 27:59

12d ago27:59

27:59

Is simplicity always the smartest choice in science? Or could complexity be the key to groundbreaking discoveries? This episode explores the evolving role of simplicity and complexity in scientific modelling, questioning the age-old principle of Occam's razor in light of modern advancements: Plurality should not be posited without necessity. Discov…

1
Car Purchase Gone Wrong to Hardware Lifecycles and Building AI Products You Want 14:56

12d ago14:56

14:56

What if the product you want doesn't yet exist? We start with the example of a car buying experience gone wrong... In this episode, Dr. Joan Palmiter Bajorek discusses her experiences with car purchasing, the challenges of hardware development, and the democratization of AI. She reflects on her search for a new car that meets her criteria, highligh…

1
Book Summary - AI vs Google: The Battle for the Gateway to the Web 7:00

12d ago7:00

7:00

Google made the internet searchable. AI is making it actionable. In this episode, we explore the seismic shift from keyword search to intelligent agents—what it means for business, behavior, and the future of the web. From SEO to LLMs, from PageRank to prompt engineering, this is the real revolution in how humans find, decide, and act online. If yo…

1
Book Summary: The Coming Wave by Mustafah Suleyman 18:55

13d ago18:55

18:55

In this episode of the CEO AI podcast, we delve into Mustafa Suleiman's book "The Coming Wave," exploring the crucial roles AI and synthetic biology are playing in shaping our future. Discussing technological waves throughout history, the episode highlights how emerging technologies today not only follow historical patterns but also introduce uniqu…

1
Article - "AI Eating Itself: The Looming Crisis of Synthetic Training Data" 14:05

14d ago14:05

14:05

In this episode of the CEO AI podcast's "Deep Dive," we delve into Gary Ambrosino's compelling article, "Is AI Eating Itself? The Future of AI Reliability?" The discussion highlights a growing concern in artificial intelligence: the potential crisis of AI models being trained predominantly on machine-generated data rather than original human conten…

1
People are Lonelier than Ever. Enter AI. 43:34

14d ago43:34

43:34

Over the last few decades, our relationships have become increasingly mediated by technology. Texting has become our dominant form of communication. Social media has replaced gathering places. Dating starts with a swipe on an app, not a tap on the shoulder. And now, AI enters the mix. If the technology of the 2010s was about capturing our attention…

1
Book Summary - The Death of Truth by Stephen Brill 22:01

15d ago22:01

22:01

In this detailed exploration of Stephen Brill's compelling book, "The Death of Truth," we delve into the erosion of truth in today's digital landscape. The episode dissects the central thesis that the decline of truth has led to a significant collapse of trust, making individuals more vulnerable to manipulation and deceit. The discussion highlights…

1
4 AI Tools I Use Weekly and How Much They Cost... Totaling LESS than $70 USD/Month 15:18

15d ago15:18

15:18

What AI tools do I actually use REGULARLY? 📊 ✍️ 🎨 🎙️ I share my favorite 4 AI tools and how much they cost. EACH saves me hours of time and work daily. Dr. Joan Palmiter Bajorek discusses 4 essential AI tools that enhance productivity and efficiency in various tasks. Tools for data management, writing assistance, design, and video/audio/podcasting.…

1
Book Summary - Competing in the Age of AI 13:22

17d ago13:22

13:22

Competing in the Age of AI by Marco Iansiti and Karim R. Lakhani examines how artificial intelligence is fundamentally reshaping businesses, covering how companies are being transformed by digital networks and the need for swift adaptation to thrive in this new economic age. The book highlights how value creation and capture are changing and discus…

1
Boards Need a More Active Approach to Cybersecurity 12:34

22d ago12:34

12:34

Cybersecurity Oversight by Boards Boards of directors must evolve their approach to cybersecurity, recognizing it as a critical business risk. Traditional views treated it as a mere IT problem, but research has revealed the need for serious attention from the highest levels. This includes making cybersecurity a routine item on the board’s agenda an…

1
Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar 15:53

20d ago15:53

15:53

Could computer simulations redefine diabetes care? In this episode, we focus on a real medical product and the role of in silico trials in the transition from the Medtronic Guardian Sensor 3 to the Guardian 4 sensor, central to the Medtronic 780G pump system, which aims to simplify diabetes management by eliminating the need for fingerstick calibra…

1
Shape of Teams of the Future: AI Builds, Workforces, Jobs, and Skillsets in 2025 and Beyond 18:10

21d ago18:10

18:10

How big of a team do you need for teams of the future? What skill sets to do these people need? Learn from conversations being had in customer meetings in May 2025. In this episode, Dr. Joan Palmiter Bajorek discusses the evolving landscape of team structures in the context of AI development. She explores the necessary skills for future team member…

1
Allegory of the 5 Companies: Which Do YOU Believe Will Be Around in a Decade? 14:33

25d ago14:33

14:33

What types of companies will be around in 10 years? In this episode, Dr. Joan Palmiter Bajorek discusses the allegory of 4... well 5 companies in the dairy industry to illustrate different approaches to adopting AI and technology. She emphasizes the importance of curiosity, engagement, and upskilling in ensuring long-term business success. The conv…

1
Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning 16:40

1M ago16:40

16:40

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance of evidence-based medicine (EBM) and evidential pluralism, emphasising the role of mechanistic evidence alongside traditional studies. Join us as we de…

1
Echo Chambers of One: Companion AI and the Future of Human Connection 42:17

1M ago42:17

42:17

AI companion chatbots are here. Everyday, millions of people log on to AI platforms and talk to them like they would a person. These bots will ask you about your day, talk about your feelings, even give you life advice. It’s no surprise that people have started to form deep connections with these AI systems. We are inherently relational beings, we …

1
What Underpins Model Credibility? Three Philosophical Perspectives 19:12

1M ago19:12

19:12

How do philosophers of science think about model evaluation? Dive deep into the crucial process of model evaluation, a fundamental step in digital science that determines the effectiveness and precision of computational models. This episode explores three primary perspectives on model quality: the mirror view, relevant similarity, and fitness for p…

1
Building AI Castles: 3 Takeaways from Customer Stories in AI Product Development 18:47

1M ago18:47

18:47

What does it mean to build AI products in 2025? What conversations are being had behind closed doors? Let's talk about it- In this episode of Your AI Roadmap, Dr. Joan Palmiter Bajorek discusses the evolving landscape of AI product development, emphasizing the importance of integrating AI into workflows, the necessity of a solid data infrastructure…

1
Exploring Digital Twins: The Philosophy Behind Healthcare's Digital Revolution 20:23

1M ago20:23

20:23

Have you ever wondered what makes a digital twin truly "twin-like" and not just another computer model? This fascinating question lies at the heart of modern healthcare innovation, where virtual copies of real-world systems are revolutionising how we approach medical research and patient care. Our latest episode delves into groundbreaking research …

1
AGI Beyond the Buzz: What Is It, and Are We Ready? 52:53

2M ago52:53

52:53

What does it really mean to ‘feel the AGI?’ Silicon Valley is racing toward AI systems that could soon match or surpass human intelligence. The implications for jobs, democracy, and our way of life are enormous. In this episode, Aza Raskin and Randy Fernando dive deep into what ‘feeling the AGI’ really means. They unpack why the surface-level debat…

1
Cracking the Code: Unveiling the Trustworthy World of In-Silico Trials 25:14

2M ago25:14

25:14

Are computational models ready to replace traditional clinical trials? This episode delves into the fascinating world of in silico trials and their growing role in regulatory evaluation of biomedical products. We explore a methodological framework based on the ASME VV-40-2018 standard that establishes credibility through verification, validation, a…

1
Rethinking School in the Age of AI 42:35

2M ago42:35

42:35

AI has upended schooling as we know it. Students now have instant access to tools that can write their essays, summarize entire books, and solve complex math problems. Whether they want to or not, many feel pressured to use these tools just to keep up. Teachers, meanwhile, are left questioning how to evaluate student performance and whether the who…

1
Revolutionising Healthcare: The Power of Synthetic Data 15:47

2M ago15:47

15:47

Is the healthcare sector prepared to harness synthetic data's transformative potential whilst navigating its hidden pitfalls? This thought-provoking episode delves into the murky waters of synthetic data governance in medical research, examining how generative AI is reshaping our approach to patient information. As algorithms increasingly create co…

1
How Can We Trust Computational Models in Healthcare? A Framework for In Silico Clinical Trials 22:57

2M ago22:57

22:57

Are you curious about how computer simulations are changing the way we evaluate medical devices? In this episode, we delve into the fascinating world of in silico clinical trials (ISCTs), a cutting-edge approach that uses computational models to assess the safety and effectiveness of medical interventions. We explore a recent paper that highlights …

1
Probability & Patients: The Stochastic Science Behind In Silico Trial Breakthroughs 13:41

2M ago13:41

13:41

𝗪𝗵𝗮𝘁 𝗶𝗳 𝘁𝗵𝗲 𝗻𝗲𝘅𝘁 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝘁𝗿𝗶𝗮𝗹 𝗯𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗶𝘀 𝗮𝗹𝗿𝗲𝗮𝗱𝘆 𝗶𝗻 𝘆𝗼𝘂𝗿 𝗰𝗼𝗺𝗽𝘂𝘁𝗲𝗿? This episode explores the fascinating world of virtual patient models and stochastic engineering, unveiling how digital simulations are revolutionising healthcare clinical trials. Discover how simulated trials using sophisticated virtual patient models—complete with variation…

1
Forever Chemicals, Forever Consequences: What PFAS Teaches Us About AI 1:04:33

3M ago1:04:33

1:04:33

Artificial intelligence is set to unleash an explosion of new technologies and discoveries into the world. This could lead to incredible advances in human flourishing, if we do it well. The problem? We’re not very good at predicting and responding to the harms of new technologies, especially when those harms are slow-moving and invisible. Today on …

1
How can we properly evaluate the true economic impact of AI in healthcare? 23:19

3M ago23:19

23:19

How are the CHEERS-AI guidelines transforming economic evaluations of healthcare AI? In our latest podcast episode, we delve into how the Consolidated Health Economic Evaluation Reporting Standards for AI (CHEERS-AI) are revolutionizing the economic assessment landscape for artificial intelligence in healthcare. Discover why transparency and consis…

1
Turning CO2 into Graphite: Climate Innovation with Homeostasis from French Fest Fireside Chat 43:42

3M ago43:42

43:42

Have you heard about turning carbon dioxide turning into graphite? In this lively fireside chat, Dr. Joan Palmiter Bajorek sits down with CEO and co-founder Makoto Eyre to explore why new ideas in climate tech matter more than ever—especially when it comes to tackling carbon dioxide’s impact on our planet. Homeostasis turns CO2 into industrial grap…

1
Revolutionising Healthcare: Inside the UK's MHRA Data Strategy 17:56

3M ago17:56

17:56

Will the MHRA's New Data Strategy Transform Healthcare Through Computational Innovation? In this episode, we explore the MHRA's groundbreaking data strategy for 2024-2027, a visionary plan heralding a fourth industrial revolution in healthcare. From supporting data-driven innovation to harnessing AI and real-world evidence, we dive deep into the st…

1
OpenAI in 2025: 5 Reasons I'm Betting Against Them 21:13

3M ago21:13

21:13

Let's talk about OpenAI's viability as a company. In this episode, Dr. Joan Palmiter Bajorek discusses OpenAI and its flagship product, ChatGPT, while expressing concerns about the company's future. Hear the detailed feedback and make up your own opinion about whether OpenAI will be one of the big winners in a 5-10 year time span. She outlines five…

1
Weaponizing Uncertainty: How Tech is Recycling Big Tobacco’s Playbook 51:20

3M ago51:20

51:20

One of the hardest parts about being human today is navigating uncertainty. When we see experts battling in public and emotions running high, it's easy to doubt what we once felt certain about. This uncertainty isn't always accidental—it's often strategically manufactured. Historian Naomi Oreskes, author of "Merchants of Doubt," reveals how industr…

1
Unleashing the Potential of Health Data: Insights from the Sudlow Review 21:58

3M ago21:58

21:58

What is the roadmap to transform how we use health data in the UK? This episode discusses the Sudlow Review and highlights the immense potential of linking health data, tackling accessibility challenges, and the importance of public trust. We discuss its five critical recommendations to make health data a national infrastructure, streamlining acces…

1
BONUS: I got laid off, then I closed an $100k contract 13:34

3M ago13:34

13:34

Dr. Joan Palmiter Bajorek shares her personal journey from being laid off to closing her first $100k contract and establishing 22 income streams, emphasizing the need for individuals to create their own stability in an uncertain job market. Bajorek discusses the importance of diversifying income streams and building financial resilience. She talks …

1
Regulatory Frontiers: UK's Centres of Excellence in Regulatory Science and Innovation 18:56

3M ago18:56

18:56

How is the UK positioning itself at the forefront of regulatory science innovation through strategic investments in centres of excellence? This episode explores the UK Government-funded Centres of Excellence in Regulatory Science and Innovation (CERSI) Initiative and its pivotal role in shaping the future regulatory landscape for AI and in silico t…

1
Can NHS Secure Data Environments Unlock the Future of UK Life Sciences? 40:06

3M ago40:06

40:06

By InSilicoUK

1
The Man Who Predicted the Downfall of Thinking 58:57

3M ago58:57

58:57

Few thinkers were as prescient about the role technology would play in our society as the late, great Neil Postman. Forty years ago, Postman warned about all the ways modern communication technology was fragmenting our attention, overwhelming us into apathy, and creating a society obsessed with image and entertainment. He warned that “we are a peop…

1
Why is AI taking off now? Technical Trifecta for AI: GPUs, Big Data, and Machine Learning 10:28

3M ago10:28

10:28

Why is AI taking off now? Dr. Joan Palmiter Bajorek answers a common question given the rapid advances around us in AI. This episode ties previous episodes together. The current hype surrounding AI technology is based on advances in on the trifecta of factors driving its growth: advancements in hardware (GPUs), the size and complexity of data sets,…

1
Virtual You vs Cancer: How Digital Twins Are Revolutionizing Treatment 22:40

4M ago22:40

22:40

What if your doctor could test hundreds of cancer treatments on a virtual version of your tumour before giving you a single dose of medication? In this episode, we dive into the fascinating concept of digital twins, particularly their application in oncology. Discover how digital twins, virtual replicas of tumours, are being used to simulate treatm…

1
“Everyone got laid off but me” Stories of Layoffs and Career Surprises 5:39

4M ago5:39

5:39

Layoffs keep happening. Dr. Joan Palmiter Bajorek discusses the emotional and practical challenges of navigating layoffs and job insecurity. She shares a personal story about a friend facing layoffs in her workplace where her boss and her whole team gets let go ... except for her. She emphasizes the importance of resilience and financial stability.…

Podcasts Worth a Listen

Proof Beyond Reason Podcasts

Podcasts Worth a Listen