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Infectious Dose

Infectious Dose

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Infectious dose is the shot of science you need to protect yourself from misinformation. Heather McSharry, PhD, an expert in viral pathogenesis, brings her blog to the airwaves to help bridge the dangerous gap between the science of infectious diseases and public misperception. On the podcast website, infectiousdose.com, all episodes have corresponding blog posts with the information contained in the episode along with links or PDFs for all sources used. To prevent unwelcome surprises, episo ...
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West Nile virus is back in the headlines, with new human cases in the U.S. and steady activity in Europe. In this episode of Infectious Dose, Heather tracks the current outbreak season through CDC and ECDC surveillance and state-level reports, explores how the virus cycles between birds and mosquitoes, and examines what happens when you get infecte…
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This week, Heather pulls back the curtain on how she figures out what’s true. From gut checks and trusted sources to the brutal training of grad school and the constant practice of science writing, she shares the habits that help her navigate conflicting claims—like the current confusion around COVID vaccine access. You don’t need a PhD to think li…
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Heather brings you a bonus mini Booster Dose episode to explain everything you need to know about the new changes in FDA-approved access to fall COVID shots, who’s eligible by brand/age, what counts as “underlying,” off-label/insurance realities, why ACIP mainly affects coverage (not labels), a brief CDC leadership update, and practical protections…
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Back-to-school season means new teachers, new friends…and a whole new round of germs. From runny noses to strep throats, pinkeye to flu, classrooms are a breeding ground for illness once the school bell rings. In this episode of Infectious Dose, Heather breaks down the most common fall outbreaks in kids, when to keep children home, and the preventi…
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In this gripping episode, we dive into the world of Vibrio vulnificus—a flesh-eating bacterium once confined to warm southern waters, now making deadly appearances from Florida to Cape Cod. We begin with real-life cases from the 2025 surge across the U.S., then uncover the science behind this microscopic killer: how it invades, how it spreads, and …
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Chikungunya is sweeping through southern China in its largest recorded outbreak—and it’s not just a local problem. In this episode of Infectious Dose, Heather takes you inside Foshan’s summer surge, unpacks how this mosquito-borne virus travels the globe, and explores why its painful symptoms can linger for months or even years. You’ll hear how two…
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What do vaccines really contain? Why do people still believe they cause autism? And who keeps spreading these lies? In honor of Immunization Awareness Month, this special episode of Infectious Dose is your guided tour through our vaccine safety series. Heather maps out the key episodes that break down myths, expose disinformation campaigns, and exp…
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In this episode, Heather unpacks one of 2025’s most urgent and underreported global health crises. Cholera—an ancient disease we know how to prevent and treat—is resurging across dozens of countries. But this isn’t about biology alone. From Sudan’s displaced families to Angola’s overcrowded clinics and the gold fields of the DRC, people are dying n…
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Rabies is one of the deadliest viruses known to science—but its cultural legacy may be even more enduring. Rabies has stalked the screen for decades, not just as a disease, but as a symbol of primal fear, uncontrollable rage, and the thin line between animal and human. This episode investigates the biology of rabies bites and its eerie neurological…
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This episode is a little different. After relaunching and dropping 18 episodes since April, Heather finally shares the personal story behind why she left her blog/podcast/social media—and why she came back. From life upheaval and burnout to pandemic loss and resilience, this is the story behind Infectious Dose. If you're new here, it's a great plac…
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As global focus drifts and vaccine narratives fade, polio—a disease once on the brink of eradication—is finding new paths to persist. In this episode, Heather unpacks the World Health Organization’s latest alerts on circulating vaccine-derived poliovirus (cVDPV2), explores newly issued travel advisories, and traces the virus’s quiet resurgence. Fro…
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This Fourth of July, we’re serving flaming absurdity alongside a tribute to scientists under attack. In this science-meets-comedy special, Heather tackles the patriotic chaos of backyard BBQs, rogue mortars, and the bacterial battleground of summer salads. Featuring real disaster stories, expert food tips, and a powerful closing tribute to U.S. sci…
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More than five years since the start of COVID-19, the virus is still here — evolving, spreading, and leaving lasting impacts. In this episode of Infectious Dose, Heather—a virologist-turned-science writer—examines the costs of the erosion of protective messaging, what new data say about reinfection, and the risks of losing vaccine access under a sh…
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What if our biggest mistake in vaccine communication wasn’t misinformation—but misexpectation? In this episode of Infectious Dose, Heather digs into the seductive myth of sterilizing immunity—the idea that a “perfect” vaccine blocks infection completely—and explores how this scientific fable has distorted public expectations, undermined trust, and …
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In this episode, Heather delves into the story of Sin Nombre virus and the disease it causes, Hantavirus Pulmonary Syndrome. From its rodent origins and rapid progression to the public health response and scientific breakthroughs that followed, we explore how a rare virus rewrote the rules of infectious disease in North America—and why it remains a…
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Heather gives updates on 2025 measles outbreaks in every region of the world and discusses global efforts to curb them. She also debunks the deadly lies about measles from RFK Jr. in her fan favorite segment WTF-RFK! and answers listener questions in her new segment Hot Zone Hotline. Explicit rating is for mild and limited profanity because, I mean…
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Invasive meningococcal disease strikes fast—and often without warning—especially in close-contact environments like college dorms and military barracks. While it’s rare, the consequences can be devastating: death within hours, or lifelong complications like limb loss and brain damage. In this episode Heather explains all about how Neisseria meningi…
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In the 5th episode in her vaccine safety series, Heather gives straightforward, science-based answers to some of the most common questions about what’s in vaccines including an in-depth look at what's in several specific vaccines and the truth debunking false claims you've seen recently in the media.…
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Anthrax is one of the oldest infectious diseases known to science. Its ability to survive harsh environments and reemerge as a deadly pathogen centuries later is a biological marvel—and a global health concern. Heather covers all you want to know about anthrax from its formidable spore structure and use as a bioweapon, to its recent outbreaks and p…
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In the second vaccine safety episode, Heather describes how Andrew Wakefield's fraudulent science cost the world the elimination of measles and hurt children. With evidence to back it up, she goes into detail on what he did and how he still manipulates parents fears to make money. Marked explicit for limited and mild profanity.…
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This is the original Pathogen Perspectives episode rebranded for Infectious Dose, originally published in 2020. Heather provides an in-depth discussion on the COVID-19 vaccine platforms other than mRNA, that were in clinical trials around the world. These include self-replicating mRNA, DNA, Protein-based, Attenuated virus, Inactivated virus, Repurp…
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This is the original Pathogen Perspectives Episode published in 2020, rebranded for Infectious Dose. Heather provides an in-depth discussion on the COVID-19 mRNA vaccines authorized for emergency use in the US. She covers: · What is mRNA · How mRNA vaccines work · How we know they are safe · Why they cannot change your DNA · How long might immunity…
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