Learn from history's greatest entrepreneurs. Every week I read a biography of an entrepreneur and find ideas you can use in your work. This quote explains why: "There are thousands of years of history in which lots and lots of very smart people worked very hard and ran all types of experiments on how to create new businesses, invent new technology, new ways to manage etc. They ran these experiments throughout their entire lives. At some point, somebody put these lessons down in a book. For v ...
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Marc Andreessen Podcasts
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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Andreessen Horowitz ("a16z") co-founders Marc Andreessen and Ben Horowitz explore everything from science to business to culture, all through the lens of technology.
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Host Mike Maples Jr. from venture capital firm Floodgate offers lessons from the rare startup super performers — BEFORE they were successful. Pattern Breakers features interviews with some of Silicon Valley’s most legendary entrepreneurs and thought leaders, including Netscape co-founder Marc Andreessen, LinkedIn founder Reid Hoffman, Instagram founders Kevin Systrom and Mike Kreiger, business maverick Mark Cuban, and Shopify co-founder Tobi Lütke.
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Conversations about science, technology, history, philosophy and the nature of intelligence, consciousness, love, and power. Lex is an AI researcher at MIT and beyond.
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Stripe cofounder John Collison interviews founders, builders, and leaders over a pint.
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A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vineeta Agarwala, Julie Yoo, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg Verdine, Fei-Fei Li, and Suchi Saria, as they explore the i ...
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Most business podcasts follow a similar format: find a successful CEO and have them tell their story. This is not that show. Zero to IPO tackles real world problems with real world experience, featuring actionable advice and anecdotes from some of the world's most innovative founders. In season one, we broke down each stage of a company's growth cycle on a granular level with everyone from Parker Harris of Salesforce.com, to Julia Hartz of Eventbrite and Marc Andreessen of Andreessen Horowit ...
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How do you grow like a VC-backed SAAS company without taking on investors? What are the secrets that SAAS CEOs have that the rest of us don't? Do you want to create a lifestyle business, a performance business, or an empire? How do you scale to an exit without losing your freedom? Join the host Ryan Staley every Monday and Wednesday for conversations with the brightest and best SAAS Founders, CEOs, and Entrepreneurs to crack the code on repeatable revenue growth, leadership, lifestyle freedo ...
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You’ll hear consequential ideas here first, and in the mainstream months later. Upstream is a curated nexus feed from the Turpentine podcast network, bringing you expert-level conversations hosted by some of the most compelling thinkers in the world including Noah Smith, Samo Burja, Byrne Hobart, Erik Torenberg, and Nathan Labenz. Guests include Marc Andreessen, Balaji Srinivasan, Dario Amodei, Brian Armstrong, David Sacks, Sam Harris, Katherine Boyle, Curtis Yarvin, and many more unmissable ...
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Your shortcut to startup wisdom. Each week, The Seminal Startup brings to life the most important, iconic, and game-changing articles ever written about building and scaling startups. Whether it's Paul Graham, Marc Andreessen, Elad Gil, or other legends of the ecosystem, we just read their words. We don't editorialize or talk about the content. This is just a startup to help you read these articles too. Perfect for founders, operators, investors, and anyone obsessed with the art of entrepren ...
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Chats between Duncan Anderson and James Peck on anything we find interesting... hopefully you find it interesting as well :) Please note all statements are the individuals own and do not represent the organisations they work for.
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Tech Talks
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Listen to your long form article at your leisure
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What if we all stopped to think a little harder? To have conversations with each other? What might the world look like? I’m Kinsey Grant and together, we’re gonna find out.
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Bill Bennett discusses the news of the day and why it matter. Clear and candid conversations with special guests who are "in the know".
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w/ Jennifer Sutto & Michael Keen: NFTs are going mainstream. Jennifer & Michael keep their audience informed about all relevant projects as the industry continues to expand. With a focus on market dynamics and turning a profit, this podcast is perfect for the seasoned NFT trader or someone that is just looking to learn what the heck is going on with these JPEGS!
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We’re witnessing a revolution in retail investing, and personal finance is more culturally relevant than ever before. Now, new questions are emerging about how our financial system works—and how it needs to change to better serve everyday people. In this podcast, we’re lifting the hood on the world of investing and exploring what it really means to democratize finance for all. Join Robinhood CEO and Co-Founder Vlad Tenev as he interviews the most interesting minds in money today—from YouTube ...
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We launched Navigating Our World in 2008 to mark our 10th anniversary as an independent firm. Each NOW conference—this year would have marked our seventh—is meant to embody our commitment to seeking out fresh and diverse views, learning from experts across disciplines, and challenging conventional assumptions. While we have shifted our conference format to a podcast series due to the pandemic, we remain steadfast in our belief that thoughtful inquiry, encompassing varied perspectives, helps ...
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AI Will Save The World with Marc Andreessen and Martin Casado
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1:03:10Originally published in June 2023, this conversation features a16z cofounder Marc Andreessen following the release of his nearly 7,000-word essay arguing that AI does not threaten our humanity. In a wide-ranging discussion with a16z General Partner Martin Casado, Andreessen expands on why he believes AI can dramatically amplify human potential, why…
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Spenser Skates: How Perseverance Paid Off for Amplitude
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44:55 When Amplitude launched in 2012, the analytics market looked crowded, and the company spent more than a year struggling to find any traction. But co-founder and CEO Spenser Skates prioritized truth seeking over narratives. He studied the outcomes of past Y Combinator batches and noticed a simple rule: Most companies died before they even learned e…
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Wartime vs Peacetime: Ben Horowitz on Leadership
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35:02In this exclusive conversation from a16z’s Bio and Health BUILD Summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. Originally released in August 2023, the episode covers everything from the inspiration behind Ben’s book The Hard Thing About Hard Things and how the open internet was secured, to the difference between w…
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The Techno-Optimist Manifesto with Marc Andreessen and Ben Horowitz
1:06:38
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1:06:38Originally aired in October 2023, this episode centers on Marc Andreessen’s essay The Techno-Optimist Manifesto, which lays out his vision for the future of technology. The piece sparked widespread discussion across traditional and social media by challenging the prevailing pessimistic narrative around technology and arguing instead that it can be …
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#488 – Infinity, Paradoxes that Broke Mathematics, Gödel Incompleteness & the Multiverse – Joel David Hamkins
Joel David Hamkins is a mathematician and philosopher specializing in set theory, the foundations of mathematics, and the nature of infinity, and he’s the #1 highest-rated user on MathOverflow. He is also the author of several books, including Proof and the Art of Mathematics and Lectures on the Philosophy of Mathematics. And he has a great blog ca…
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The Inside Story of Growth Investing at a16z
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28:48This episode is a special replay of David George’s conversation with Harry Stebbings on 20VC. David is a General Partner on a16z’s growth team, and in this discussion he breaks down how he thinks about breakout growth investing: why great business models are now table stakes, where real edge comes from non-consensus views on TAM, and how to underwr…
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Why a16z's Martin Casado Believes the AI Boom Still Has Years to Run
1:22:20
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1:22:20This episode is a special replay from The Generalist Podcast, featuring a conversation with a16z General Partner Martin Casado. Martin has lived through multiple tech waves as a founder, researcher, and investor, and in this discussion he shares how he thinks about the AI boom, why he believes we’re still early in the cycle, and how a market-first …
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#408 How to Make a Few MORE Billion Dollars: Brad Jacobs
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43:29In 2024 Brad Jacobs wrote the book How to Make a Few Billion Dollars. In the book Brad explains how he built 8 separate billion dollar companies and other lessons from his 40+ year career as an elite entrepreneur. In the two years since Brad has made a few MORE billion dollars and so the sequel to his first book is: How to Make a Few MORE Billion D…
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Where Does Consumer AI Stand at the End of 2025?
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44:22As 2025 comes to a close, consumer AI is entering a new phase. A small number of products now dominate everyday use, multimodal models have unlocked entirely new creative workflows, and the big labs have pushed aggressively into consumer experiences. At the same time, it is becoming clearer which ideas actually changed user behavior and which ones …
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Big Ideas 2026: New Infrastructure Primitives
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20:21New infrastructure primitives are creating entirely new rails for building. In this episode of Big Ideas 2026, we explore three foundational shifts that unlock new markets and workflows, not through incremental upgrades, but through primitives that compound over time. First, programmable money evolves beyond stablecoins into on-chain credit origina…
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The Life of Jesus as told in the book Jesus: A Biography of a Believer by Paul Johnson. This episode was originally published on Christmas Eve 2023.By David Senra
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Big Ideas 2026: Physical AI and the Industrial Stack
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21:34AI is moving into the physical economy. In this episode of Big Ideas 2026, we explore what changes when AI leaves the screen and becomes part of factories, construction sites, supply chains, and critical infrastructure. When the product is physical, reliability matters, real-world constraints appear quickly, and the advantage shifts from standalone…
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Big Ideas 2026: Voice Agents and High-Stakes Trust
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17:44Voice is becoming one of the fastest paths for AI to do real work, especially in regulated environments where accuracy and compliance matter. In this episode, we look at voice agents replacing and augmenting phone-based workflows, what trust and measurement look like when AI runs sensitive interactions, and how healthcare and consumer products shif…
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Big Ideas 2026: The Enterprise Orchestration Layer
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22:18AI is becoming the orchestration layer inside the enterprise. In this episode of Big Ideas 2026, we explore the shift from isolated AI copilots to coordinated multi-agent systems that plan, analyze, and execute work across teams and tools. This is not a new feature, but a new way workflows run inside large organizations. You will hear from Seema Am…
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AI is moving from chat to action. In this episode of Big Ideas 2026, we unpack three shifts shaping what comes next for AI products. The change is not just smarter models, but software itself taking on a new form. You will hear from Marc Andrusko on the move from prompting to execution, Stephanie Zhang on building machine-legible systems, and Sarah…
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The Rise, Fall & Reset of The Fintech Industry
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45:14Fintech went from a full-blown surge to a near standstill in just two years. At its peak, about 25 percent of all venture dollars were pouring into the category. By late 2022, that number had collapsed to almost zero. In this conversation, a16z General Partner David Haber and Plaid cofounder and CEO Zach Perret unpack what actually happened during …
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Do Revenue and Margins Still Matter in AI?
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1:02:30In this episode, we’re sharing a conversation with David George, General Partner at a16z on the firm’s growth investing team. David has been involved in backing many of the defining companies of this era and is now investing behind a new wave of AI startups. This discussion goes deep into how the a16z growth practice operates: how the team hires an…
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The Crime Crisis In America and How Technology Fixes It
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59:30What if America tried to eliminate crime instead of just reacting to it? Not with slogans, but with staffing, technology, and strategy scaled to the problem. In this episode, Erik Torenberg speaks with Garrett Langley, founder and CEO of Flock Safety, and Ben Horowitz, cofounder of a16z, about what is happening in the cities that are trying. Flock …
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Ryo Lu (Cursor): AI Turns Designers to Developers
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52:01Ryo Lu spent years watching his designs die in meetings. Then he discovered the tool that lets designers ship code at the speed of thought: Cursor, the company where Ryo is now Head of Design. In this episode, a16z General Partner Jennifer Li sits down with Ryo to discuss why "taste" is the wrong framework for understanding the future, why purposef…
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#407 Bruce Springsteen Repairs the Hole in Himself
1:12:53
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1:12:53A viciously unhappy childhood causes Bruce Springsteen to retreat into work in an extreme way as he searches for success (and control). He channels his pain into focus and drive and gets everything he thought he wanted. He didn’t yet know he was lying to himself. He will find that out soon. He falls into a deep depression. One that almost leads to …
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Irving Finkel is a scholar of ancient languages and a longtime curator at the British Museum, renowned for his expertise in Mesopotamian history and cuneiform writing. He specializes in reading and interpreting cuneiform inscriptions, including tablets from Sumerian, Akkadian, Babylonian, and Assyrian contexts. He became widely known for studying a…
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AI Eats the World: Benedict Evans on the Next Platform Shift
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1:02:50AI is reshaping the tech landscape, but a big question remains: is this just another platform shift, or something closer to electricity or computing in scale and impact? Some industries may be transformed. Others may barely feel it. Tech giants are racing to reorient their strategies, yet most people still struggle to find an everyday use case. Tha…
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Jonathan Swanson has built two rare successes: Thumbtack, the home-services marketplace, and Athena, the fast-growing platform that pairs ambitious people with world-class personal assistants. Today he runs a 4,000-person company, invests on the side, and raises four kids — all by designing his life around leverage. a16z General Partner, Erik Toren…
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Originally published on the a16z Infra podcast. We're resurfacing it here for our main feed audience. AI coding is already actively changing how software gets built. a16z Infra Partners Yoko Li and Guido Appenzeller break down how "agents with environments" are changing the dev loop; why repos and PRs may need new abstractions; and where ROI is sho…
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The 80-Year Bet: Why Naveen Rao Is Rebuilding the Computer from Scratch
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30:11Naveen Rao is cofounder and CEO of Unconventional AI, an AI chip startup building analog computing systems designed specifically for intelligence. Previously, Naveen led AI at Databricks and founded two successful companies: Mosaic (cloud computing) and Nervana (AI accelerators, acquired by Intel). In this episode, a16z’s Matt Bornstein sits down w…
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What Comes After ChatGPT? The Mother of ImageNet Predicts The Future
1:01:56
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1:01:56Fei-Fei Li is a Stanford professor, co-director of Stanford Institute for Human-Centered Artificial Intelligence, and co-founder of World Labs. She created ImageNet, the dataset that sparked the deep learning revolution. Justin Johnson is her former PhD student, ex-professor at Michigan, ex-Meta researcher, and now co-founder of World Labs. Togethe…
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How AI Created the Fastest Product Cycle in History
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50:54Recently, a16z General Partner Anish Acharya joined Ollie Forsyth on NEW ECONOMIES. They talked about why consumer tech is surging again, how AI is enabling 100M-user products at unprecedented speed, and what founders need to understand heading into 2026 — from distribution shifts to founder mindset to the mechanics behind the fastest product cycle…
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In this episode, a16z GP Julie Yoo sits down with Peter McCanna, CEO of Baylor Scott & White Health, to break down how one of America's largest health systems is transforming from a supply-driven "walled castle" to a customer-centric ecosystem, and how it's achieving a 10% operating margin while most hospitals struggle to stay in the black. They ge…
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Christian von Koenigsegg is unapologetically in the pursuit of greatness. Koenigsegg builds some of the fastest and most expensive cars on Earth, has a cult-like following, and relentlessly seeks out challenges he can innovate on. After building his company for more than 30 years, his love and passion for his craft is still as strong as ever. This …
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Why AI Moats Still Matter (And How They've Changed)
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51:31a16z General Partners David Haber, Alex Rampell, and Erik Torenberg discuss why 19 out of 20 AI startups building the same thing will die - and why the survivor might charge $20,000 for what used to cost $20. They expose the "janitorial services paradox" (why the most boring software is most defensible), explain why OpenAI won't compete with your o…
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How To Lead | Ben Horowitz on My First Million
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1:10:40A16Z co-founder Ben Horowitz joins Shaan Puri and Sam Parr on My First Million to talk about how to be a great leader. Resources: Follow Ben on X: https://x.com/bhorowitz Follow Shaan on X: https://x.com/ShaanVP Follow Sam on X: https://x.com/thesamparr Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your frien…
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The $700 Billion AI Productivity Problem No One's Talking About
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58:17Russ Fradin sold his first company for $300M. He’s back in the arena with Larridin, helping companies measure just how successful their AI actually is. In this episode, Russ sits down with a16z General Partner Alex Rampell to reveal why the measurement infrastructure that unlocked internet advertising's trillion-dollar boom is exactly what's missin…
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Michael Levin is a biologist at Tufts University working on novel ways to understand and control complex pattern formation in biological systems. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep486-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https…
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How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning
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53:24In this episode, a16z GP Martin Casado sits down with Sherwin Wu, Head of Engineering for the OpenAI Platform, to break down how OpenAI organizes its platform across models, pricing, and infrastructure, and how it is shifting from a single general-purpose model to a portfolio of specialized systems, custom fine-tuning options, and node-based agent …
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92. Is there an AI bubble? Thoughts On What Markets Are Really Pricing In. Mentioning Warren Buffet, Paul Volcker, Larry Page & More
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1:05:35This blog is the best explanation of AI intelligence increase I've seen: https://metr.org/blog/2025-03-19-measuring-ai-ability-to-complete-long-tasks/### Defining Market Bubbles- Traditional definition: 20%+ share price decline with economic slowdown/recession- Alternative perspective: hype/story not matching reality over time (dot-com example)- Du…
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Ben Horowitz: Why Open Source AI Will Determine America's Future
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46:50Ben Horowitz reveals why the US already lost the AI culture war to China—and it wasn't the technology that failed. While Biden's team played Manhattan Project with closed models, Chinese developers quietly captured the open-source heartbeat of global AI through DeepSeek, now running inside every major US company and university lab. The kicker: Goog…
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The Secret Marketing Strategy That Built a16z: From Zero to Legendary VC Firm
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59:55Marc Andreessen and Ben Horowitz sit down with Margit Wennmachers—the woman who turned two unknown entrepreneurs with $300 million and zero investing track record into the most talked-about firm in venture capital. She unpacks how they weaponized transparency in an industry built on secrecy, why Fortune's cover story triggered a cartel meltdown, an…
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The Secret Marketing Strategy That Built a16z: From Zero to Legendary VC Firm
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58:30Marc Andreessen and Ben Horowitz sit down with Margit Wennmachers—the woman who turned two unknown entrepreneurs with $300 million and zero investing track record into the most talked-about firm in venture capital. She unpacks how they weaponized transparency in an industry built on secrecy, why Fortune's cover story triggered a cartel meltdown, an…
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I'm reposting one of my favorite founder stories. If you listened to this first time I recommend listening again. If you missed this before, you're about to hear one of the wildest founder stories of all time. A few surprising things I learned from reading about Dietrich Mateschitz, founder of Red Bull: 1. He started the company when he was 41 year…
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Half a billion people can access the world’s best AI on their phone. So why are most using it to write emails while only some are using it to build empires? In this conversation with Mark Halperin from Next Up, Marc Andreessen reveals why small bakeries are beating Fortune 500 companies at AI adoption, how to turn ChatGPT into your personal board o…
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Julia DeWahl of Antares on building nuclear reactors for the US military
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45:17Julia DeWahl is the cofounder of Antares, a company developing nuclear micro-reactors for the US military and critical infrastructure. She sits down with John to discuss the vision for the "Starlink of electricity", and why AI hyperscalers are driving a nuclear renaissance. They cover the bipartisan shift in nuclear regulation (and why the NRC’s ol…
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The Future of Healthcare Payments: CMS Chief of Staff Stephanie Carlton
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26:53A labor and delivery nurse who ran Senate healthcare policy now manages $1.7 trillion in federal health spending—and she runs her team like a startup. Steph Carlton, Chief of Staff and Deputy Administrator at CMS, reveals the OKRs driving Medicare and Medicaid, why they're killing social determinants funding while building consumer health apps at s…
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