Best KGK Science Podcasts (2025)

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Episode 68- From Substance to State: How the Cognalyzer Is Redefining Cannabis Impairment Testing 36:38

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1h ago36:38

36:38

The legalization of cannabis has created a billion-dollar problem that technology is only now catching up to solve: how can we accurately measure impairment, not just use? In this episode of the Orange Pill Podcast, we dive into groundbreaking research featuring the Cognalyzer®- a novel EEG-based device that measures brainwave alterations to detect…

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Episode 67- A Major New Study Reveals a Surprising Way to Reduce Aggression by up to 30% 46:52

2d ago46:52

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Aggression, from playground fights to serious violence, has long challenged families and communities alike. But what if one of the simplest, safest, and most effective tools for reducing aggression has been sitting on our dinner plates all along? In this episode, we explore a groundbreaking new meta-analysis spanning nearly 30 years of research tha…

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Episode 66: The Super-Nutrients in Your Food Aren’t Working - and How Nanotech Could Change That 42:40

17d ago42:40

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We all try to eat better, loading up on antioxidant-rich berries, turmeric, and green veggies, but here’s the surprising truth: many of those “super-nutrients” never make it past your digestive system. In this episode of the Orange Pill Podcast, we explore how nanotechnology is rewriting the rules of nutrition. From nanoencapsulation that protects …

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Episode 65- The Hidden Dangers of Biogenic Amines: Why Setting Specifications Matters for Foods and Supplements 39:50

19d ago39:50

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Fermented foods like cheese, wine, and cured meats are celebrated for their complex flavors, but they may harbor hidden risks. In this episode of The Orange Pill Podcast, we explore the world of biogenic amines (BAs), naturally occurring compounds that can pose health hazards despite their delicious origins. From the “cheese effect” of tyramine to …

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Canada’s CBD Crossroads: Health Canada’s Next Big Move for Cannabis and NHPs 29:02

22d ago29:02

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In Episode 64, we continue to unpack the regulatory evolution of cannabis and cannabidiol (CBD) in Canada (continuation of Episode 44) and what’s next for the industry. From the Cannabis Act to proposed pathways that could finally allow CBD Natural Health Products (NHPs) to be sold without prescriptions, this episode dives deep into how Health Cana…

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Episode 63- Government Shutdown 2025: From Furloughs to Firing 24:34

27d ago24:34

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For most Americans, a government shutdown means furloughs, temporary disruptions that end when funding returns. But October 2025 marks a turning point. The Trump administration’s move to issue Reductions in Force (RIFs) across key agencies like HHS, FDA, and the CDC has transformed a short-term budget standoff into a permanent restructuring of the …

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Episode 62- NMN is Back: Inside the FDA’s Reversal on a Top Anti-Aging Ingredient 23:32

1M ago23:32

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By KGK Science

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Episode 61-More Than Weight Loss: How the Bone Broth Diet Preserves Muscle, Reduces Hunger & Improves Health 40:34

1M ago40:34

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Most diets promise weight loss but leave you battling hunger, losing precious muscle, and facing rebound weight gain. But what if there’s another way? In this episode of the Orange Pill Podcast, we break down a recent clinical trial published in Clinical Nutrition Open Science that tested the Bone Broth Diet (BBD), a mix of intermittent fasting, hi…

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Episode 60- The Fermentation Revolution: 5 Ways an Ancient Art Is Shaping the Future of Food 40:52

1M ago40:52

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From sourdough bread to kombucha, fermentation has long been a cornerstone of human diets. But what was once a preservation method is now driving some of the boldest innovations in food science. In this episode, we explore five surprising ways fermentation is transforming the future of food—from unlocking hidden nutrition and reintroducing microbia…

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Episode 59- The Invisible Revolution: How AI & IoT Are Quietly Transforming Your Food 35:32

2M ago35:32

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From farm to fork, our food supply chain is one of the most complex in the modern world. But while we often imagine technology’s role as simply faster machines or warehouse robots, the true disruption is happening in ways we don’t see. In Episode 59 of the Orange Pill Podcast, we uncover four surprising ways AI and IoT are secretly reshaping the fo…

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Episode 58- Caffeine Under the Microscope: Safety in Foods & Supplements 32:57

2M ago32:57

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Caffeine is the world’s most widely consumed psychoactive substance, naturally found in coffee, tea, and chocolate, but now added to everything from energy drinks and supplements to waffles and chewing gum. With this rapid expansion, regulators and health experts are re-examining the science and safety of caffeine consumption. In this episode, we b…

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Episode 57- Perks and Pitfalls: The Evolving Landscape of U.S. Coffee & Caffeine Consumption 27:04

2M ago27:04

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Coffee and caffeine are cultural cornerstones in the United States, but consumption trends have shifted dramatically over the past century. From the wartime rise of instant coffee to today’s specialty café culture and booming energy drink market, Americans’ relationship with caffeine keeps evolving. In this episode of the Orange Pill Podcast, we un…

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Episode 56: D-Mannose Breakthrough: A Natural Ally for Women’s Urinary Health 46:42

2M ago46:42

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In this episode of the Orange Pill Podcast, we explore the promise of D-mannose, a functional sugar gaining recognition as a non-antibiotic solution for urinary tract infections (UTIs). We break down findings from a randomized, triple-blind, placebo-controlled study (Current Urology, 2025) where the product UClear, developed by KEB Nutraceuticals a…

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Episode 55: Make America Healthy Again: The MAHA Strategy to Reverse Childhood Chronic Disease 44:59

2M ago44:59

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In Episode 55 of the Orange Pill Podcast, we dive into the newly released “Make Our Children Healthy Again Strategy” from the Make America Healthy Again (MAHA) Commission, chaired by U.S. Health and Human Services Secretary Robert F. Kennedy Jr. This landmark strategy, unveiled on September 9, 2025, lays out more than 120 initiatives to combat the …

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Episode 54: From TikTok to Tacos: Gen Z’s Food Habits 33:12

2M ago33:12

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Gen Z is reshaping the future of food. From sustainability and ethics to bold flavors, functional foods, and the powerful role of social media, their choices reflect values as much as taste and price. In this episode, we explore what drives Gen Z’s food preferences, the trends that matter most, and what brands need to know to stay relevant in a mar…

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Episode 53- Clinical Trial Statistics & Interpretation: Beyond the P-Value 45:28

2M ago45:28

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Statistics can make or break the credibility of a clinical trial, but too often they’re misunderstood. In this episode, we dive into the statistical backbone of clinical research — P-values, null hypothesis, sample size, effect size, and safety data — and uncover the common misconceptions that can distort how results are interpreted. From the chron…

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Episode 52: The Pink Tax on Pills: Decoding the $91B Women’s Health Supplement Market 44:29

2M ago44:29

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The women’s health supplement market is booming, projected to hit nearly $91 billion by 2033. But is this growth empowering women, or exploiting them? In this episode, we unpack the drivers behind the surge, from the self-care movement and influencer marketing to life-stage–specific formulas targeting PMS, fertility, and menopause. We also dive int…

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Episode 51: The Protein Bar Arms Race and the Rise of “David” 36:53

3M ago36:53

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The protein wars are heating up, and one bar is leading the charge. In this episode, we unpack the “protein bar arms race” and the meteoric rise of the David Bar—a hyper-optimized, influencer-backed product redefining the category. From its extreme protein-to-calorie ratio and luxury branding to its aggressive supply chain play with Epogee, David i…

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Episode 50: The End of Secret Ingredients: GRAS Reform in 2025 54:13

3M ago54:13

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The FDA’s “Generally Recognized as Safe” (GRAS) rule was meant to keep food safe. But for decades, the self-GRAS loophole has allowed companies to introduce new additives without FDA review or public disclosure. In this episode of the Orange Pill Podcast, we break down the unprecedented wave of reform efforts in 2025: Executive action from HHS Secr…

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Episode 49: Leaked Report: Can MAHA Really Make America Healthy Again? 41:33

3M ago41:33

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In this episode, we dive deep into the Make America Healthy Again (MAHA) Commission’s leaked strategy report, submitted to President Trump earlier this month and quietly leaked before its official release. The “Make Our Children Healthy Again Strategy” lays out sweeping changes to how the federal government addresses childhood chronic disease, from…

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Episode 48:Tariffs, Trade & Turbulence: How the EU-US Deal Shakes the Supplement Industry 25:43

3M ago25:43

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The new EU-US trade deal is here, and it’s sending shockwaves through the dietary supplement industry. While it avoids the 30% tariff originally proposed, the agreement imposes a steep 15% tariff on about 70% of EU exports to the US, up from the previous 1.2%. In this episode, we break down: Who’s Hit Hardest: Why finished dietary supplements aren’…

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Episode 47: Federal Action on Ultra-Processed Foods 40:47

3M ago40:47

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In this episode, we unpack a major federal push to tackle the diet-related chronic disease crisis in America, with ultra-processed foods (UPFs) in the crosshairs. The U.S. Departments of Health and Human Services and Agriculture, working alongside the FDA and NIH, are launching coordinated initiatives to: Define “ultra-processed foods” with a unifo…

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Episode 46: The GRAS "Loophole" and Robert F. Kennedy Jr.'s Regulatory Stance 23:35

3M ago23:35

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In this episode of the Orange Pill Podcast, we dive into Health Secretary Robert F. Kennedy Jr.’s aggressive push to dismantle the GRAS (“Generally Recognized as Safe”) pathway — a move that’s shaking up both Big Food and the supplement industry. We explore: The origins and exploitation of the GRAS "loophole" Why ultraprocessed foods are in the cro…

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Episode 45: FDA Actions on Kratom and 7-Hydroxymitragynine (7-OH) 31:50

3M ago31:50

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The FDA is sounding the alarm. In a major regulatory move, the agency is recommending that 7-hydroxymitragynine (7-OH)—a potent synthetic derivative of kratom—be scheduled under the Controlled Substances Act. Why? Because this lab-created version of kratom’s active compound is up to 500% more potent than its natural form and is increasingly tied to…

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Episode 44: Canada's Evolving CBD Regulations and Market Outlook 28:29

3M ago28:29

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This episode explores Canada’s evolving approach to CBD regulation, focusing on proposed changes that would allow low-dose cannabidiol products to be sold as Natural Health Products without a prescription. It covers the gaps in the current framework under the Cannabis Act, the results of public consultations, and Health Canada’s ongoing efforts to …

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Episode 43: Cost Recovery Chaos – What’s Really Happening to Canada’s Natural Health Products? 18:05

3M ago18:05

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Part One of Our Deep Dive into NHP Regulation Reform Canada’s Natural Health Product (NHP) industry is facing its biggest regulatory shake-up in decades — and we’re here to break it all down. In this must-listen episode, we unpack the newly revised Product Licence Application (PLA) Class system and the controversial cost recovery program introduced…

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Episode 42: Beta-Alanine’s Emerging Role in Cognitive Health and Depression 35:30

4M ago35:30

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This episode explores the surprising benefits of CarnoSyn® beta-alanine beyond sports. A new study reveals that a low, sustained-release dose improved cognitive function and reduced depression scores in older adults with below-average baseline scores—without side effects. We break down the science behind brain carnosine, its link to BDNF and mood, …

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Episode 41: The "Ensuring Safe and Toxic-Free Foods Act" and GRAS System Reform 22:02

4M ago22:02

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In this episode, we unpack the newly introduced Ensuring Safe and Toxic-Free Foods Act of 2025, spearheaded by Senators Markey and Booker. This legislation aims to reform the FDA’s GRAS (Generally Recognized as Safe) system, which has long allowed food companies to self-approve potentially harmful additives without FDA oversight. We explore how thi…

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Episode 40: The Impact of Magnesium on Brain Health and Aging 15:57

4M ago15:57

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Can magnesium slow brain aging? New research says yes. This episode breaks down emerging evidence on magnesium’s role in preserving brain volume, protecting against white matter lesions, and lowering dementia risk. We explore why post-menopausal women see the strongest benefits, how magnesium regulates neuroinflammation, and what you can do to incr…

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Episode 39: Tariff policies are reshaping the dietary supplement industry—are you prepared? 28:23

4M ago28:23

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How do tariffs shape your supplements? In this episode, we break down the economic and regulatory impact of the 2025 Reciprocal Tariff System and Executive Order 14257 on the dietary supplement industry. Learn how key ingredients like CoQ10 and Vitamin B Complex secured tariff exemptions—saving the industry over $200 million in just over two months…

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Episode 38: Crossing Barriers: The Omega-3 Breakthrough with Lysoveta 29:32

4M ago29:32

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In this episode of the orange pill podcast, we spotlight a groundbreaking clinical trial that could redefine how omega-3s are delivered to the brain and eyes. Aker BioMarine has partnered with KGK Science to launch the first-ever human clinical trial on Lysoveta, a next-gen omega-3 ingredient that uses lyso-phosphatidylcholine (LPC) to deliver EPA …

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FDA's Human Foods Program and New Dietary Ingredient (NDI) Guidance 35:59

4M ago35:59

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In this episode of the Orange Pill Podcast, we unpack the FDA’s newly released 2025 Human Foods Programme guidance agenda and the persistent challenges stalling finalization of the long-awaited New Dietary Ingredient (NDI) guidance. From the implications of regulatory orders that demand a "10-for-1" rule, to open questions around bioidentical molec…

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Episode 36: Class Action Lawsuit Against Amazon Regarding Misleading Supplement Labels 20:00

4M ago20:00

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In this episode of the Orange Pill Podcast, we unpack the federal class action lawsuit alleging deceptive labeling practices on dietary supplements sold through one of the world’s largest online retailers. Plaintiffs claim the company systematically omits mandatory disclaimers and promotes unapproved health claims—leaving consumers under the false …

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Episode 35: Unreliable Melatonin Supplement Doses and Safety Concerns 33:57

5M ago33:57

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A new FDA study reveals that many melatonin supplements—especially those marketed for children—contain wildly inaccurate doses, ranging from 0% to over 600% of what is listed on the label. In this episode, we unpack the science and regulatory implications of this inconsistency. Why is a powerful hormone treated like a harmless vitamin? What does th…

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Episode 34: Paraxanthine as a Caffeine Alternative 21:56

5M ago21:56

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Episode 34 takes a closer look at paraxanthine (Px) — the main metabolite of caffeine — and why it might be the next big thing in clean, functional energy. With claims of fewer jitters, smoother focus, and a safer toxicity profile, Px is drawing attention from both scientists and the beverage industry. This episode explores: How paraxanthine compar…

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Episode 33: Psyllium Husk – "Nature’s Ozempic" and Beyond 33:55

5M ago33:55

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Psyllium husk is taking the wellness world by storm, but is it just hype, or a true hero in your supplement stack? In this episode, we break down what makes psyllium more than just a fiber. From its rising nickname “Nature’s Ozempic” to its documented benefits in digestion, heart health, and even colorectal cancer prevention, we look at where the s…

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Episode 32: Efficacy of Probiotic Supplementation for Constipation and Well-being in Older Adults 30:18

5M ago30:18

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In this episode, we explore the findings of a newly published clinical trial investigating the impact of an 84-day probiotic regimen on gut and mental health in older adults aged 50–85 who experience occasional constipation. The probiotic blend—Lactiplantibacillus plantarum strains KABP031 and KABP032 (marketed as INNERIM™)—was tested in a randomiz…

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Episode 31: Determining Whether Human Research Studies Can Be Conducted Without an IND 19:04

5M ago19:04

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The FDA’s guidelines on when human research studies require an Investigational New Drug (IND) application can be a maze for researchers and sponsors. In this episode, we break it all down for you: from the broad definition of "drugs" under the FD&C Act to exemptions in clinical investigations. We discuss the core criteria that help you determine if…

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Episode 30: Review of the FDA Bioresearch Monitoring (BIMO) Program 34:42

5M ago34:42

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The FDA’s Bioresearch Monitoring (BIMO) program is more than just inspections—it's a regulatory safeguard for the rights and welfare of clinical trial participants and the integrity of data used to support FDA submissions. In this episode, we break down the scope and function of the BIMO program, explore common findings during inspections, and disc…

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Episode 29: A GOOD IDEA for Better Blood Sugar 34:20

5M ago34:20

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In today's episode, we explore a clinically studied nutritional supplement drink made with five amino acids and chromium — shown to reduce post-meal blood sugar levels by up to 25%. We break down the research, the claims, and what it could mean for metabolic health, diabetes prevention, and the supplement industry as a whole.…

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Episode 28: Natural Relief- The Science Behind Relieve-R and Its Role in Pain Management 53:27

5M ago53:27

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In this episode, we unpack a fascinating clinical trial conducted by KGK Science for LifeSeasons Inc., evaluating the natural health product Relieve-R (formerly Pain Bloc-R) as an alternative for occasional pain relief and inflammation. Published in the journal Nutrients, this randomized, double-blind, placebo-controlled crossover study compared Re…

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Episode 27: A Novel trial design by KGK Science on Unigen’s UP446 Ingredient to Demonstrate a Positive Immune Defense Response 17:21

5M ago17:21

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In this episode, we explore an innovative clinical trial by KGK Science evaluating Unigen’s UP446, a natural health ingredient composed of Acacia catechu and Scutellaria baicalensis. Designed as a randomized, triple-blind, placebo-controlled study, this trial used a human vaccine model to assess immune response following influenza vaccination. We d…

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Episode 26- FDA Continues to Allow Companies to Use NDIs Submitted by Competitors - the Practice of Piggybacking 11:13

6M ago11:13

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In this episode on the Orange Pill Podcast, we tackle a long-standing regulatory loophole: piggybacking on NDI submissions. While companies like Natural Alternatives International (NAI) invest in proper safety and regulatory filings, like their recent successful NDI notification for CarnoSyn® beta-alanine, authored by the regulatory team at KGK Sci…

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Episode 25: MAHA Commission Report – Big Beautiful (FDA) Blueprint 16:07

6M ago16:07

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The MAHA Commission Report is expected to be released today—and it’s already making waves. In this special pre-release episode, we explore what to expect from the report, and how it could reshape conversations around policy, governance, and the future. As the noise ramps up, we give you the context and clarity you’ll need to navigate the headlines.…

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Episode 24: Nestle Launches Salmon Oil Supplement with Hofseth's OmeGo 11:35

6M ago11:35

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In this episode, we explore Nestlé’s U.S. debut of a salmon oil supplement under the Garden of Life brand, featuring OmeGo — a unique whole fish extract by Hofseth Biocare. We break down what makes this omega-3 product stand out in a crowded market, the role of sustainability and full-spectrum benefits, and how KGK Science supported Hofseth in obta…

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Episode 23: Sustainability: The Future of the Dietary Supplement Industry 8:52

6M ago8:52

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As consumer demand grows for clean, conscious products, the supplement industry is being called to evolve. In this episode, we explore the many ways companies can engage in sustainable sourcing and production—from eco-friendly packaging and ethical ingredient procurement to promoting responsible consumer practices. Learn how reducing plastic waste,…

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Episode 22: Pollen Extracts for Female Urinary incontinence 13:13

6M ago13:13

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In this episode, we explore how flower pollen extracts are being studied as a potential solution for urinary incontinence in women. We break down the latest clinical evidence from a newly published trial in Current Urology, conducted by KGK Science and sponsored by Graminex®. We’ll discuss: The impact of urinary incontinence on daily life How flowe…

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Episode 21: The Sleep Secret Hidden in Corn Leaves 14:15

6M ago14:15

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We are back with a deep dive into the world of sleep — and why melatonin may not be the long-term solution we’ve all been promised. In this episode we cover: Why melatonin is widely used in hospitals, yet many still struggle to sleep What makes sleep so critical to overall health The growing global demand for new, effective sleep supplements A look…

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Episode 20: History of the US Food Supply : Before and After FDA 13:04

6M ago13:04

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In this episode, we uncover the shocking state of America’s food supply before the FDA — from toxic milk to candy laced with arsenic — and explore how those chaotic beginnings shaped the future of food, supplements, and regulation.By KGK Science

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Episode 19: KGK Science and Nimble Science: Revolutionizing GI Health Research 10:47

6M ago10:47

10:47

In this episode of the Orange Pill Podcast, we talk about the exciting new partnership between KGK Science and Nimble Science. Learn how this collaboration is set to redefine gastrointestinal (GI) health research through the integration of SIMBA™, a novel ingestible capsule that collects high-quality gut samples—without invasive procedures.…