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The Boston Globe

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Big ideas and big debates, explained through intimate conversations with the compelling personalities who shape them. AI and biotech. Higher education and health care. Climate and sustainability. Politics and the media. Culture and culture wars. Hosted by Boston Globe columnist Shirley Leung.
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Health Unchained Podcast

Health Unchained Podcast

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Health Unchained dives into healthcare projects enabled by blockchain technology. Listen to healthcare leaders, executives, entrepreneurs, researchers, and medical professionals who share their insights and experience.
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Today, we’re sharing the first episode from My Home Fronts , a podcast from journalist Romy Neumark. My Home Fronts is a four-parts documentary podcast series tracing the student founder of "Jews for Palestine" at Harvard during the Gaza war - and the generational gap it reveals within American Jewish families. Episode 1, "Meeting Violet": An unexp…
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The Israel-Hamas war took place more than 5,000 miles away from here, but you wouldn’t know that from the intensity of protests happening on US college campuses. Israeli journalist Romy Neumark works at Harvard University, and was curious to understand her own blind spots about how Israel is perceived in Jewish American homes. In Neumark’s new podc…
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After years of lobbying, Massachusetts has convinced toy company Hasbro to move its global headquarters from Rhode Island to Boston. Massachusetts is the historic home of many iconic toy companies, like Milton Bradley and Parker Brothers, and now, Hasbro joins Lego for another era of toy making. The question is, should we really be celebrating stea…
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The exact causes of autism are unknown - but you wouldn’t know that from listening to President Trump and his health secretary RFK Jr., who recently announced Tylenol was to blame. The science behind the announcement is not solid - but more troublingly, it falls into an old pattern of blaming mothers for autism, which creates a culture of stigma, s…
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The Boston Museum of Fine Arts has announced a major reshuffle of its American Revolutionary War galleries. The goal, it says, is to tell an ‘inclusive’ story of America’s founding. Meanwhile, in Washington, President Trump has threatened the Smithsonian over similar moves. Globe editorial page editor Jim Dao talks to Ethan Lasser, curator of Ameri…
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This is a re-run of the first episode of our series "The C-Word" which originally aired May 1, 2025. Boston Globe columnist Shirley Leung is generally open about her personal life. But this is the first time she is talking publicly about her own experience with breast cancer. She was treated in Boston hospitals and underwent a mastectomy. Like so m…
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President Donald Trump wants Harvard to cough up at least $500 million. Longtime Harvard professor Steven Pinker says it's extortion. And Harvard should do it anyway. Globe columnist Carine Hajjar, filling in for host Shirley Leung, talks to Steven Pinker about caving to the Trump administration and where to draw the line. Email us at saymore@globe…
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The Market Basket board of directors fired its CEO, 'Artie T.' Demoulas, on September 9th after a very public - and very nasty - succession battle. Host Shirley Leung and Globe Business Reporter Jon Chesto get into the messy family dynamics and how other New England business dynasties manage to make it work. Email us at [email protected]. Check out…
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Boston Mayor Michelle Wu trounced challenger Josh Kraft in Tuesday’s preliminary election for Boston mayor. What makes Wu so successful? And can she be a model for Democrats nationally? Say More host Shirley Leung talks to Boston Globe politics reporter Emma Platoff and columnist Joan Vennochi about the ‘Trump effect’ on the mayoral election. Email…
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Dr. Alex Cahana is a pain medicine physician and expert in ethical AI. Dr. Cahana reflects on changes since his last appearance in 2019, including the rise in Bitcoin prices, Purdue Pharma's settlement, and emerging interest in decentralized technologies. The conversation touches on the challenges of building trust in society, the ethical principle…
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It's perhaps never been more exhausting to be a mom. In her book, "Repair with Self-Care: Your Guide to the Mom's Hierarchy of Needs" author Leslie Forde calls on moms to find to put themselves first and prioritize their own health and well being, even when things are busy. Leslie Forde joins host Shirley Leung on today's episode of Say More.…
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Today, we’re bringing you the third and final installment of The Outlaw Ocean podcast’s investigation into the shadowy work of the Libyan Coast Guard. The podcast looks into efforts to capture and detain migrants crossing the Mediterranean Sea in the hopes of a new life in Europe. This week’s episode describes how members of the Outlaw Ocean team w…
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More than 50 million people make their living working offshore on the two-thirds of our planet covered by water. Today, we’re bringing you episode two from the second season of “The Outlaw Ocean,” a podcast from the Outlaw Ocean Project, a journalism non-profit that investigates human rights, forced labor, and environmental concerns on our planet's…
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More than 50 million people make their living working offshore on two-thirds of our planet covered by water. The non-profit Outlaw Ocean Project is dedicated to exploring human rights violations, forced labor, and environmental problems that plague the world’s oceans. Over the next few weeks, we’re bringing you a three-part story from the second se…
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Welcome back to Generally Intelligent! We’re excited to relaunch our podcast—still featuring thoughtful conversations on building AI, but now with an expanded lens on its economic, societal, political, and human impacts. Matt Boulos leads policy and safety at Imbue, where he shapes the responsible development of AI coding tools that make software c…
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It wasn’t long ago that finding an Asian American novelist in a local bookstore felt like finding a rare flower. Today, the options overflow. Viet Thanh Nguyen was on the leading edge of that wave. His first novel, The Sympathizer, won the Pulitzer Prize in 2016. Since then he has written a sequel, a collection of short stories, books for children,…
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In 2018, the Supreme Court struck down a law that banned sports betting, and ushered in a new era of gambling. Sports betting has become a multi-billion dollar industry. It’s as ubiquitous as it is lucrative. In his new book “Losing Big: America’s Reckless Bet on Sports Gambling” Jonathan Cohen argues that the rise of online sports betting, fueled …
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Democrats are at a crossroads. According to recent polling from CNN, just 28% of Americans view the party favorably. The lowest rating in the poll’s 30-plus year history. Critics say the party lacks vision, and fails to connect with voters. Some say, the party is out of touch. Others believe it’s simply gone too far to the left. But there are new v…
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The Michelin Guide is known for identifying the crème de la crème of dining in the nation’s hottest cities. And for the first time, it’s coming to Boston. Today on Say More, Shirley Leung is joined by Boston Globe Restaurant Critic Devra First to discuss what Michelin means for the city, and how the challenges facing Boston restaurants, including h…
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It's a uniquely challenging time for our nation's medical community. The Trump administration has set its sites on slashing federal funding for healthcare and research by tens of billions of dollars, which could be catastrophic for the NIH and CDC. Funding is tenuous to say the least. Then there's mounting political pressure to restrict access to c…
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The 4th of July. What does it mean to you? This week it's America's birthday, a day that recognizes the signing of the Declaration of Independence, a blueprint for Democracy. It's a celebration that comes around every year, yet this time it feels different. Globe Opinion asked readers and community members to reflect on what it means to be an Ameri…
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Kevin Sack is a longtime reporter who spent much of his career writing long-form pieces for the New York Time. Then in 2015, he helped cover one of the most horrific massacres in recent US history, the killing of nine parishioners who were attending Bible study at the Emanuel African Methodist Episcopal Church in Charleston, South Carolina. The sto…
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Today, we’re sharing a special episode from Endless Thread, a podcast from our friends at WBUR. Brooke Eby was 33 when she was diagnosed with ALS. Since then, she’s gained a huge following for her honest and often hilarious videos about the realities of living with the disease. In this episode, Brooke speaks with Endless Thread hosts Ben Brock John…
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United States Immigration and Customs Enforcement is making itself known in Massachusetts. Federal immigration officials say they’ve arrested nearly 1,500 people over the last month in what they're calling, “Operation Patriot.” ICE officers have taken people off the streets, on their way to school, and from courthouses. They’ve made it clear that t…
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With the moving of tassels and tossing of caps, the school year has come to a close at Harvard. And what a tumultuous year it has been. President Donald Trump has gone to war with the nation's most elite university. The White House has canceled a sweeping array of grants and contracts worth billions of dollars with no plans to let up. Then, in late…
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Gianluca De Novi, founder and CEO of Circular Protocol, a Massachusetts-based layer one blockchain built on a proof of reputation consensus mechanism joins host, Ray Dogum. Circular is designed to help partners accelerate innovation in healthcare and decentralized science (DeSci) through secure, reputation-driven infrastructure. Gianluca is a hands…
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When we think about being young, we picture a time of exploration and discovering who we are. What we don't picture? Cancer. But there's a worrying trend in the cancer world with young adults getting cancer at higher rates, and scientists don't know why. Kelly Spill was 28 years old when she was diagnosed with colorectal cancer. She was pregnant wh…
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For years, journalist Larry Ingrassia thought his family was tragically unlucky. His mother, two sisters, and brother all died of cancer. Later in life, he understood it was no coincidence: threaded throughout his family’s DNA was a hereditary cancer gene, vastly increasing their risk of the deadly disease. In this episode, Shirley talks to Larry a…
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Cancer doctor Barrett Rollins only discovered the extent of his wife’s advanced cancer when she collapsed at work, revealing a football sized breast tumor. Barrett’s wife Jane, also a world-class cancer researcher, confounded her entire community when it was revealed that she had hidden her own cancer diagnosis for years, only sharing the truth whe…
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Dr. Elliot Justin, founder and CEO of MyFirmTech, discusses the pioneering work his company is doing in the realm of smart wearables designed for sexual health. With a background in emergency medicine, Dr. Justin aims to eliminate the stigma around erectile dysfunction by using real data and insights. He explores the company's innovative technology…
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Dr. Siddhartha Mukherjee became famous with his epic nonfiction book about cancer, “The Emperor of All Maladies.” The book shows that if there’s one constant in cancer research, it’s that it’s always changing. On this episode of “The C-Word: Stories of Cancer,” Shirley talks to Dr. Mukherjee about how his time living and working in Boston changed h…
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Dr. Brandon Crawford, DC FIBFN-CND, is a board-certified developmental functional neurologist and global laser expert. He discusses his work on laser and light therapy to transform patient lives. Dr. Crawford shares his journey from chiropractic training to pioneering functional neurology and photobiomodulation. He explains how different wavelength…
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Boston Globe columnist Shirley Leung is generally open about her personal life. But this is the first time she is talking publicly about her own experience with breast cancer. She was treated in Boston hospitals and underwent a mastectomy. Like so many others, she will spend the rest of her life getting tested to make sure she stays cancer-free. In…
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Guests Nitin Gaur, ex IBMer & CTO of LedgerLink.ai, and Jim Nasr, CEO of Acoer, discuss decentralized healthcare and life sciences initiatives. The conversation explores the Coalition for Decentralized Healthcare and Life Sciences (CDHLS), which aims to unite global stakeholders from healthcare, technology, academia, and regulatory sectors to enhan…
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If it's an important slice of American history, you can bet Ken Burns has made a documentary about it. The list is nearly endless. From baseball to jazz, Mark Twain to Ernest Hemingway, the Civil War to the Dust Bowl. Now, he's going back to the beginning. Burns’s upcoming documentary series, out later this year, will explore the Revolutionary War …
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Eleanor Davies is the Head of DeSci at the Sei Foundation. Eleanor previously helped launch VitaDAO, the first tokenized longevity venture studio, she served as Operating Partner at Cerebrum DAO, and was COO at Convexity Labs (previously known as LabDAO). With deep experience bridging web3, biotech, and healthcare, Eleanor shared her unique insight…
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Today, we’re sharing the first episode of the brand new podcast Spotlight: Snitch City, produced by The Boston Globe's award-winning Spotlight team. In this specific episode, you’ll find yourself on the docks of New Bedford, Massachusetts, hearing whispers about a rogue police officer harassing fishermen and stealing drugs, all of which come to a h…
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When it comes to the war on drugs, you could say the police are addicted to confidential informants. That’s the conclusion of a new Boston Globe Spotlight investigation into the pervasive and shadowy world of this police practice that is widely used and barely regulated. The story starts in New Bedford Massachusetts, where use of informants has had…
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Laura Epstein, CEO and founder of Pulse Charter Connect, along with Chris Tyler, Pulse's Chief Technology Officer, join host Ray Dogum in an episode you won’t want to put on ice. They dive into their backgrounds and share how their company is revolutionizing organ transportation logistics to save time—and lives. Pulse Charter Connect (PCC) digitize…
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Being a working parent can be a rewarding joy, but it’s also an endless challenge. This week, Say More is happy to share its first LIVE show, recorded from the Boston Globe’s inaugural Working Mothers Summit in Boston. In the episode, Shirley talks to Mayor Michelle Wu about her decision to parent in public, even bringing baby Mira on stage. Then, …
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Canadian Journalist Stephen Marche says he’s experiencing the most powerful moment of Canadian politics in his lifetime. The trigger has been Donald Trump’s presidency and his antagonistic stance towards Canada, one of the US’s closest historic allies and trading partners. On this episode of Say More, Shirley talks to Marche about the ways Canadian…
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Massachusetts has one of the oldest and most successful publicly run lottery systems in the country. It shouldn’t surprise you that per adult, MA residents spend more on the lottery than any other state, by a wide margin. But if you dig into the numbers, the problems with the lottery system start to become visible - tickets are more likely to be bo…
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Former New York Times Beijing bureau chief Jane Perlez will pay $1 million to whoever knows what President Trump will do when it comes to China. Ok, not really, but Jane says Trump’s plans are hugely important, and anyone’s guess. Jane is now a fellow at Harvard University’s Kennedy School, and is the host of the podcast, Face-Off: The U.S. vs Chin…
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Tristan Roberts, founder of Dog Years DAO, a decentralized autonomous organization focused on improving canine longevity. They discuss the potential of using blockchain technology to manage decentralized trials and gather data more effectively. Tristan shares his journey from cognitive neuroscience to biohacking and gene therapy, detailing his expe…
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Boston Mayor Michelle Wu was called to Washington this week to answer questions about Boston’s so-called "sanctuary city” status. At a Congressional hearing, she, and 3 other blue-city mayors, were grilled by Republicans who say that Boston’s lack of collaboration with federal immigration officials puts residents in danger. Wu refuted this point, a…
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The first days of the COVID pandemic feel like a movie looking back: we watched in horror as the virus ravaged China, Italy, and Iran - and wondered if we would be next. Now, five years later, we know what happened: the economy suffered from a prolonged shutdown, more than one million Americans died, and political polarization reached an all-time h…
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David Stefanich, Nina Kilbride, and Dr. Sarin Movsisyan from CureLedger join host Ray Dogum to discuss their upcoming token launch. The discussion centers on CureLedger, an initiative aimed at transforming the decentralized science (DeSci) landscape through blockchain and Web3 technologies. David speaks about Rymedi’s foundational software for Clem…
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The story of Sandra Birchmore may never have made headlines if it wasn’t for Laura Crimaldi, a Boston Globe reporter who spent years following the trail of Birchmore’s life and tragic death. While Birchmore’s death was originally ruled as a suicide, follow up investigations showed she was involved in an inappropriate relationship with a married Sto…
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Privacy. Period. Anna Hall is the founder and CEO of Embody Space, a menstrual cycle tracking and wellness app with 50k+ users, that prioritizes data privacy through local encryption and open-source technology. Anna shares her journey from an educator to a startup founder, driven by her own diagnosis of PMDD and the need for secure menstrual health…
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Michelle Wu is the first Boston Mayor to have a baby while in elected office, and while it was unprecedented, it wasn’t much of a news story. Pregnancy is increasingly normalized for powerful women, which is a sign of progress. But Wu’s decision to forgo maternity leave brings up important questions about the politics of motherhood: Can a champion …
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