Best Jack Sinclair Podcasts (2026)

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Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick 40:18

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7m ago40:18

40:18

In this Huberman Lab Essentials episode, my guest is Dr. Rhonda Patrick, PhD, a biomedical scientist and a leading health educator focused on nutrition, aging and general health. We discuss four key micronutrients that influence cellular stress responses, inflammation, detoxification and longevity, and how to increase your intake of each through di…

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Defining Healthy Masculinity & How to Build It | Terry Real 2:50:30

1d ago2:50:30

2:50:30

Terry Real is a therapist and best-selling author expert on male emotional health and how men can build the skills for healthy relating to others: in relationships, work, friendships and to themselves. We discuss how mixed and ever-changing messages about what masculinity is are impacting the mental and physical health of men and boys. Terry explai…

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Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett 42:10

3h ago42:10

42:10

In this Huberman Lab Essentials episode, my guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We explain how to improve hormone levels across the lifespan in both men and women using behavioral, nutritional and exercise-based …

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AI in 2025: The Real Wins, Real Fails, and What’s Next (Year in Review) 1:14:19

3d ago1:14:19

1:14:19

**AI moved fast in 2025. The bigger story? The people building with it.** In this Year in Review, Chris & Mark recap the biggest themes from the last 13 episodes—what founders got right, where “AI strategy” goes wrong, and why *experts* (not just “humans”) need to be in the loop as tools get more powerful. We unpack the show’s pivot from a weekly A…

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Utter Goodness w/ Audrey Lee 1:15:15

4d ago1:15:15

1:15:15

Utter Goodness is an upcoming short story collection written by Audrey Lee and published by Farthest Heaven. Its thirteen stories are lovely character studies, various faces of that peculiarly American form of cultural maximalism, and each rendered in very lithe prose. There's a kinda extemporising quality to the writing here, if one could extempor…

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Transform Pain & Trauma Into Creative Expression | David Choe 3:54:08

3d ago3:54:08

3:54:08

David Choe is a world-renowned artist, writer, podcaster and TV host. He tells how as a child, he was made to believe he was destined for greatness but also that he was a complete disgrace, leading him to channel his energy—including deep shame—into art that brought him global recognition. He shares about his addictions that put him on a decades-lo…

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Essentials: How to Set & Achieve Goals 37:43

7d ago37:43

37:43

In this Huberman Lab Essentials episode, I explain how to use science-based tools to better set and achieve goals. I discuss the neuroscience of goal pursuit and how dopamine and visual attention shape motivation and effort. I explain whether visualizing success or failure better supports goal pursuit, how to choose goals at the right level of diff…

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Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard 3:17:00

10d ago3:17:00

3:17:00

Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don’t just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vita…

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Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg 39:27

14d ago39:27

39:27

In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University. We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-styl…

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AI Fixing Workplace Burnout, Emotion & Psychological Safety - Dr Nathan Jones 1:08:05

21d ago1:08:05

1:08:05

Can AI actually make us more emotionally intelligent instead of more robotic? In this episode of the Digital Nexus Podcast, we sit down with Dr Nathan Jones – musician, MTV/Nickelodeon voiceover artist turned psychologist, researcher and co-founder of Mood.ai, an emotional intelligence and psychological safety platform for workplaces. Nathan unpack…

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Master the Creative Process | Twyla Tharp 2:30:06

17d ago2:30:06

2:30:06

Twyla Tharp is a world-renowned dancer, choreographer and expert on the creative process. She explains how to achieve creative success by keeping a highly disciplined routine that ultimately allows you to bring your creative visions to life. She explains how to establish a central message for each project, how to think about your audience, navigate…

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#134 - The Decline of the West (Vol. II - Chapters VII-IX) - Oswald Spengler w/ Gabe 'Skyrim Pseudomorphosis' Sinclair 2:26:01

25d ago2:26:01

2:26:01

Chapters VIII, VIII and IX, titled 'Problems of the Arabian Culture', are some of the most fun in all of Spengler's work. In order to properly illuminate Spenglerian concepts like pseudomorphosis, the Pagan Church, the second religiousness, Islam as Magian Civilisation, and more, Gabe and I did what we do best: talk about gaming in Spenglerian term…

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Essentials: The Science of Making & Breaking Habits 40:59

21d ago40:59

40:59

In this Huberman Lab Essentials episode, I explain how to create lasting habits and break unwanted ones. I explain two habit-building systems: one aligned with daily rhythms and another based on a 21-day cycle of forming and reinforcing habits. I also discuss why habit formation differs between individuals and how certain "linchpin" habits can make…

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Crowbar w/ Andrew Edwards 1:30:55

24d ago1:30:55

1:30:55

Andrew Edwards is the author of the novels King of Dogs (2019) and Crowbar (2025), both of which are well worth reading. King of Dogs is a tense action novel, while Crowbar feels like reading Programmed to Kill and watching thirty conspiracy thrillers at the same time during a speed comedown. It's a lot. For this episode, I softballed Andy with sim…

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Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery 2:14:40

24d ago2:14:40

2:14:40

Dr. Glen Jeffery, PhD, is a professor of neuroscience at University College London and a leading expert on how different colors (wavelengths) of light impact cellular, organ and overall health. He explains that long-wavelength light (red, near-infrared and infrared) can enter the body and brain to enhance mitochondrial function and thereby improve …

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Essentials: Using Hypnosis to Enhance Mental & Physical Health & Performance | Dr. David Spiegel 39:52

28d ago39:52

39:52

In this Huberman Lab Essentials episode, my guest is Dr. David Spiegel, MD, the Associate Chair of Psychiatry & Behavioral Sciences, Director of the Center on Stress and Health, and Director of the Center for Integrative Medicine at Stanford University School of Medicine. We discuss the science and clinical applications of hypnosis, including how h…

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AI vs The Creative Industry: Why It’s Changing for Good | with aiCandy Founders 1:16:20

1M ago1:16:20

1:16:20

Can you shoot a Cannes-level ad with no cameras, a fraction of the budget and a 99% lower carbon footprint? That’s exactly what Kent Boswell and Marcus Tesoriero are doing with aiCandy, one of the first AI film production studios built for brands and agencies. In this episode of Digital Nexus, we unpack how they’re turning “impossible” ideas from o…

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Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi 3:07:42

1M ago3:07:42

3:07:42

My guest is Dr. Thaïs Aliabadi, MD, board-certified OB/GYN, surgeon and leading expert in women's health. We discuss polycystic ovary syndrome (PCOS) and endometriosis, two very common yet frequently undiagnosed causes of female infertility. Dr. Aliabadi explains the symptoms, underlying causes and evidence-based treatments for both conditions, inc…

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#133 The Regime of the Brother: After the Patriarchy - Juliet Flower MacCannell w/ Stephen G Adubato 1:32:31

1M ago1:32:31

1:32:31

The Regime of the Brother is a book of psychoanalytic feminist theory (particularly leaning on Lacan), explaining why we no longer live in an Oedipal patriarchy, but rather live in a 'sham-Oedipus' regime of the brother. Neo-totemism, the primal hoard, the narcissistic ego as a consequence of failed symbolic castration and, consequently, no entry i…

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Essentials: Science of Building Strong Social Bonds with Family, Friends & Romantic Partners 36:48

1M ago36:48

36:48

In this Huberman Lab Essentials episode, I discuss the science of social connection and how we form meaningful bonds with others. I explore the neural basis for "social homeostasis"—our drive for a certain amount of social interaction—which explains why we feel lonely, seek connection and how we navigate social hierarchies. I also explain how the b…

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Farthest Heaven w/ Bill Ballard 1:46:40

1M ago1:46:40

1:46:40

Farthest Heaven is publishing some of the most exciting poetry and (soon!) fiction around today. I got to talk to the First Consul (an in-house naming convention) of Farthest Heaven, Bill Ballard, about book design, finding great authors, his approach to editing, what it means to run a small press, and a whole lot more. I was really looking forward…

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Stop Treating AI Like a Toy - Building real Workflows and AI Digital Twins w/ Tim Rayner 59:26

1M ago59:26

59:26

In this episode of Digital Nexus, Chris and Mark are joined by Dr Tim Rayner — AI Philosopher, author of Hacker Culture and the New Rules of Innovation, and educator at UTS Business School — to unpack how AI can move from “smart autocomplete” to genuine teammates that help people think better, learn faster and build braver. If you’re a founder, pro…

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How to Speak Clearly & With Confidence | Matt Abrahams 2:26:35

1M ago2:26:35

2:26:35

My guest is Matt Abrahams, lecturer at Stanford Graduate School of Business and a world expert in communication and public speaking. He explains how to speak with clarity and confidence and how to be more authentic in your communication in all settings: public, work, relationships, etc. He shares how to eliminate filler words ("umm"-ing), how to ov…

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Essentials: Breathing for Mental & Physical Health & Performance | Dr. Jack Feldman 50:00

1M ago50:00

50:00

In this Huberman Lab Essentials episode, my guest is Dr. Jack Feldman, PhD, a Distinguished Professor of Neurobiology at the University of California, Los Angeles, and a leading expert in the science of breathing. We explain the mechanics of breathing and the neural circuits that generate and regulate our breathing rhythm. We also discuss how breat…

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The Loveable for Games - Tempest ai the one prompt game creator with Jack Wakem 47:38

1M ago47:38

47:38

Can AI make game dev truly “prompt to play”? Jack Wakem (Founder, Tempest AI) breaks down how his team is building “Lovable for games” — a consumer platform where anyone can prompt, iterate, and ship, including a timeline that lets you scrub your build like a YouTube video. Tempest started as an AI-native RPG engine (RAG, context engineering, custo…

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How Your Thoughts Are Built & How You Can Shape Them | Dr. Jennifer Groh 2:16:49

2M ago2:16:49

2:16:49

My guest is Dr. Jennifer Groh, PhD, professor of psychology and neuroscience at Duke University. She explains how our brain encodes sights and sounds and integrates them so we can navigate and understand the world around us. She explains what thoughts really are and how what you focus on determines your thoughts, not just in that moment but your fu…

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£, flesh and Femoid w/ Aaron Barry 2:27:27

2M ago2:27:27

2:27:27

£, flesh and Femoid are a novella and novel, respectively, written by Aaron Barry and published by McBussy Publishing. Both star poorly-adjusted female leads suffering terminal brainrot, and both are written in a dense, internet-inflected style. In line with both books' preoccupations, this episode we talked about how to write the internet (and wha…

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Essentials: Erasing Fears & Traumas Using Modern Neuroscience 40:00

2M ago40:00

40:00

In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses. I explain why successful fear treatment requires both extinction of the old fearful response and replacement with a new positive association—not just cognitive reframing. I also explain how the thr…

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How Relevance AI & Build Club Turn Demos into Customer Ready AI Products w/ Annie Liao 53:29

2M ago53:29

53:29

Digital Nexus Ep 42: Annie Liao, From Community to Company: Building AI Products That Actually Ship What does it take to turn AI hype into shipped products? Annie Liao (Build Club / Relevance AI) joins us to unpack agentic workflows, community-led product discovery, and the mindset founders need to go from idea to MVP and revenue, fast. Annie share…

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Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum 1:59:08

2M ago1:59:08

1:59:08

My guest is Dr. David Fajgenbaum, MD, professor of translational medicine and human genetics at the University of Pennsylvania. He explains how, unbeknownst to most doctors, many approved medications can successfully treat or even cure diseases other than the ones they are typically used to treat. He shares his story of escaping death from Castlema…

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#132 Pretty Boys Are Poisonous - Megan Fox w/ Aaron Barry aka Jasper Ceylon 2:12:01

2M ago2:12:01

2:12:01

Pretty Boys Are Poisonous (2023) is a poetry collection written by actress Megan Fox. Mostly focusing on her troubled relationship with professional machine-gun Colson Baker, the poems are surprisingly adolescent for a (currently) 39-year-old mother of four. To assist me in parsing these poems, Aaron Barry, aka Jasper Ceylon, joined me for this epi…

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Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair 39:07

2M ago39:07

39:07

In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the b…

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From Mental Health App to Indy Jeff Quach on Building AI Families Actually Trust 50:57

2M ago50:57

50:57

From hacking mainframes to building Haven (mental health) and now Indy, an AI co-pilot helping families navigate paediatric and developmental care, Jeff Quach shares a builder’s journey grounded in anthropology, trust, and real-world impact. We unpack when AI should support human care (not replace it), why guardrails matter, how to find the right c…

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Officeparks w/ Noam Hessler 1:26:51

2M ago1:26:51

1:26:51

Officeparks is a wonderful poetry collection from Noam Hessler, and yet another winner published by Farthest Heaven. Romantic, funny, and shot through with an easy, natural experimentation, Officeparks is a real treat. I'm trying hard not to be too effusive in my praise, in case people think I'm being disingenuous, but these poems really are that g…

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Improve Your Lymphatic System for Overall Health & Appearance 1:40:01

2M ago1:40:01

1:40:01

Here I explain the lymphatic system, a crucial bodily network for overall health and appearance. I explain how the lymphatic system works to remove cellular waste and fluid from your organs and combat infections. I provide science-based tools that support your lymphatic system for the sake of health and appearance, including: how to reduce fluid re…

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Essentials: The Science of Gratitude & How to Build a Gratitude Practice 39:31

2M ago39:31

39:31

In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice. I explain why common gratitude practices (like simply listing things you're grateful for) are far less impactful than engaging in story-based gratitude practices. I also explain how being grateful activ…

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AI Doom, Hope & the Builders Shaping Australia’s Future - Hosted at SXSW 2025 37:05

2M ago37:05

37:05

AI isn’t the enemy, it’s the experiment of our lifetime. At SXSW Sydney 2025, we took Digital Nexus onto the floor and into the streets to ask a simple question: doom or hope? From late-night hackathons to founders shipping agentic workflows, this episode captures how Australians are actually building with AI. We go behind the scenes with builders …

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How to Overcome Inner Resistance | Steven Pressfield 2:15:17

2M ago2:15:17

2:15:17

My guest is Steven Pressfield, author of The War of Art and expert in how to overcome the inner force of "resistance"—the self-sabotaging tendency to procrastinate on your life's most important work that keeps you from realizing your professional and creative potential. Steven shares actionable tools for defeating inner resistance that work. His ap…

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#131 This Hoe Got Roaches in Her Crib - Quan Millz w/ Slater aka Simpulacra 1:21:32

2M ago1:21:32

1:21:32

Quan Millz is a maestro of urban fiction. Since 2017, he has self-published over 70 books and (apparently) made more than $500,000 from titles such as Old THOT Next Door, Pastors Eat Pwussy Too, Pregnant by My Gay Stepdaddy, and, the subject of today's episode, This Hoe Got Roaches in Her Crib. It's a tale of characters who make remarkably poor dec…

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Essentials: How Your Brain Functions & Interprets the World | Dr. David Berson 40:39

2M ago40:39

40:39

In this Huberman Lab Essentials episode, my guest is Dr. David Berson, PhD, a professor of neuroscience at Brown University and an expert on the visual system and circadian biology. We explore how the brain processes visual information, from photons entering the eye to conscious perception in the cortex. We discuss color vision, the discovery of me…

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How AI Could Heal a Generation Mental Health to AI Leader w/ Nicole Gibson 1:03:36

2M ago1:03:36

1:03:36

Can AI help understand our emotional state? Nicole Gibson, founder of Love Out Loud and co-founder of inTruth, shares how a recovery journey became a product mission, and how she’s using AI in mental health to scale evidence-based impact, leadership, and a love-led culture. Watch for: From anorexia recovery to national advocate → AI product leader …

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Protect & Improve Your Hearing & Brain Health | Dr. Konstantina Stankovic 2:27:57

2M ago2:27:57

2:27:57

My guest is Konstantina Stankovic, MD, PhD, Professor and Chair of Otolaryngology at Stanford School of Medicine. She explains how hearing works and why hearing loss—affecting over 1.5 billion people—impacts people of all ages. We discuss how hearing loss impairs focus and increases the risk of cognitive decline, as well as the role of menopause an…

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Like You Have a Choice w/ Ivan Niccolai, aka Notes from the Periphery 1:36:49

3M ago1:36:49

1:36:49

Like You Have a Choice is the first short story collection from Ivan Niccolai, the man behind the Notes from the Periphery Substack. We talk about Melbourne's inner-north, wogs, JG Ballard, Mark Fisher, Nick Land, bilingual writing, watering the driveway on Sunday morning (wogs), accelerationism, lemon trees in the back yard (wogs), illegal satelli…

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Essentials: Time Perception, Memory & Focus 33:55

3M ago33:55

33:55

In this Huberman Lab Essentials episode, I explore how biological rhythms and neurochemicals impact our perception of time. I describe how the body aligns with daily and seasonal light cycles to regulate hormones that influence energy, mood and motivation throughout the year. I share science-based tools to enhance focus and productivity, including …

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Prompt Like a Product Pro in ChatGPT & Claude: The 3-Phase System you must know (w/ Bastian Epskamp) 42:57

3M ago42:57

42:57

By Chris Sinclair and Mark Monfort

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How to Make Yourself Unbreakable | DJ Shipley 3:42:50

3M ago3:42:50

3:42:50

My guest is DJ Shipley, a retired Tier 1 operator Navy SEAL and now a top public educator on how to build mental and physical health and reach top-level performance in any endeavor. DJ’s life is one marked by extraordinary strivings, wins, setbacks and comebacks that together have shaped his approach to overcoming challenges of all kinds and to dai…

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#130 Eumeswil - Ernst Jünger w/ Brad Kelly 2:07:07

3M ago2:07:07

2:07:07

Eumeswil (1977) is one of Jünger's final novels, and is bizarre, inscrutable, and wonderful. It is, in many ways, a glassy dramatisation of the second volume of Oswald Spengler's The Decline of the West, and also an introduction to Jünger's archetype of the anarch, a series of odd animal metaphors, a collection of fragmented musings by a survivor o…

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Essentials: How Humans Select & Keep Romantic Partners in the Short & Long Term | Dr. David Buss 36:00

3M ago36:00

36:00

In this Huberman Lab Essentials episode, my guest is Dr. David Buss, PhD, a professor of psychology at the University of Texas at Austin and a pioneer in the field of evolutionary psychology. We explore the science behind human mate selection in both short- and long-term relationships. We discuss universal traits valued in long-term partners along …

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Enhance Your Learning Speed & Health Using Neuroscience Based Protocols | Dr. Poppy Crum 2:36:05

3M ago2:36:05

2:36:05

My guest is Dr. Poppy Crum, PhD, adjunct professor at Stanford, former Chief Scientist at Dolby Laboratories and expert in neuroplasticity—our brain’s ability to change in response to experience. She explains how you can learn faster and ways to leverage your smartphone, AI and even video games to do so. We also discuss “digital twins” and the futu…

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Grendel VVept/Playing God w/ C.P. Serret 1:23:49

3M ago1:23:49

1:23:49

Grendel VVept is a bizarre book that I can kind of describe as Joycean cosmic horror, but that doesn't cover everything. Traveling through time and prose styles, from today to Renaissance Italy to Sumer to ages even more distant, it's disorienting in a fascinating way. Playing God, the other book of Serret's that I read for this episode, is a tight…