Best Dwarkesh Patel Podcasts (2025)

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Some thoughts on the Sutton interview 11:39

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1h ago11:39

11:39

I have a much better understanding of Sutton’s perspective now. I wanted to reflect on it a bit. (00:00:00) - The steelman (00:02:42) - TLDR of my current thoughts (00:03:22) - Imitation learning is continuous with and complementary to RL (00:08:26) - Continual learning (00:10:31) - Concluding thoughts Get full access to Dwarkesh Podcast at www.dwa…

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#1002 - Andrew Doyle - Political Violence & The Lunatics of Your Own Side 2:33:01

21h ago2:33:01

2:33:01

Andrew Doyle is Titania McGrath, host of GB News, a comedian and a writer. The world has shifted dramatically over the past few years, and the pace of change has only accelerated in recent months. Ideas that once lived outside the mainstream have quickly entered the Overton Window, while others have been pushed out. So what does the future hold for…

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Sora and the Infinite Slop Feeds + ChatGPT Goes to Therapy + Hot Mess Express 1:05:54

2d ago1:05:54

1:05:54

This week, we’re talking about the new A.I.-generated video tools and social media feeds from Google, Meta and OpenAI. Is this how A.I. is going to cure cancer? Then, the psychotherapist Gary Greenberg stops by to discuss his recent New Yorker essay about treating ChatGPT as a patient, and why what he saw left him unsettled. And finally, all aboard…

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Software is Eating Labor 26:49

1h ago26:49

26:49

Software has fundamentally changed the way we record, store, and share information. Its next act is to fundamentally change the nature of our economy, capturing trillions of dollars of value in the process. In this talk from the 2025 a16z LP Summit, a16z General Partner Alex Rampell discusses the history of filing cabinets and databases, how SaaS p…

1
The Ben & Marc Show: China Has Scale. Can America Catch Up? 57:16

3d ago57:16

57:16

Ben, Marc, and Erik Torenberg are joined by Brian Schimpf, Co-Founder & CEO of Anduril, and Chris Power, Founder & CEO of Hadrian. Together, they dig into America’s defense production gap: why the U.S. can out-innovate but not out-produce—and what it will take to turn that around. They discuss why U.S. war games show we run out of munitions in a we…

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#1001 - Ryan Holiday - Stoicism’s Lessons on Becoming Wise 1:52:43

4d ago1:52:43

1:52:43

Ryan Holiday is a podcaster, marketer and an author.If intelligence were enough, the smartest among us would also be the wisest. Yet time and again, they stumble over life’s simplest lessons. Wisdom isn’t about knowing more; it’s about seeing deeper. So how do we shed the illusion of being ‘smart,’ and actually grow into wisdom?Expect to learn what…

1
MCP Servers: Teaching AI to Use the Internet Like Humans 51:40

4d ago51:40

51:40

If your MCP server has dozens of tools, it’s probably built wrong. You need tools that are specific and clear for each use case—but you also can’t have too many. This creates an almost impossible tradeoff that most companies don’t know how to solve. That’s why we interviewed Alex Rattray, the founder and CEO of Stainless. Stainless builds APIs, SDK…

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MCP Servers: Teaching AI to Use the Internet Like Humans 51:39

5m ago51:39

51:39

If your MCP server has dozens of tools, it’s probably built wrong.You need tools that are specific and clear for each use case—but you also can’t have too many. This creates an almost impossible tradeoff that most companies don’t know how to solve. That’s why we interviewed Alex Rattray, the founder and CEO of Stainless. Stainless builds APIs, SDKs…

1
Cheeky Pint: Marc Andreessen, John Collison & Charlie Songhurst on Tech’s Big Questions 2:09:12

4d ago2:09:12

2:09:12

Today we’re sharing a feed drop from Cheeky Pint, where Stripe cofounder and president John Collison chats with legends in technology over a pint of Guinness. In this episode, John is joined by a16z cofounder Marc Andreessen and tech investor Charlie Songhurst for a candid conversation about bubbles, downturns, and the psychology of markets. They d…

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Uncapped #26 | Ali Rowghani 41:10

1d ago41:10

41:10

Ali Rowghani is the founder of First Harmonic, a go-to-market program purpose-built for seed stage founders. Ali has had a long, distinguished career in tech. He worked with Steve Jobs and Ed Catmull at Pixar for nine years holding various roles including CFO and SVP of Strategic Planning, took Twitter from $0 in revenue through IPO as the CFO and …

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Building an AI Physicist: ChatGPT Co-Creator’s Next Venture 54:20

5d ago54:20

54:20

Scaling laws took us from GPT-1 to GPT-5 Pro. But in order to crack physics, we’ll need a different approach. In this episode, a16z General Partner Anjney Midha talks to Liam Fedus, former VP of post-training research and co-creator of ChatGPT at OpenAI, and Ekin Dogus Cubuk, former head of materials science and chemistry research at Google DeepMin…

1
Controlling the options AIs can pursue 55:34

18h ago55:34

55:34

On boxing AIs, and on making deals with them. Text version here: https://joecarlsmith.com/2025/09/29/controlling-the-options-ais-can-pursueBy Joe Carlsmith

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#1000 - Matthew McConaughey - The Art of Living a Courageous Life 1:58:00

6d ago1:58:00

1:58:00

Matthew McConaughey is an Academy Award-winning actor, producer and an author. Expect to learn why Matthew says life often “rhymes”, why it’s okay if you do everything right and still not get the result you want, how Matthew views the role courage plays in his life, how to learn to deal with failure, the difference between a nice guy and a good man…

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Eating with Intelligence (with Julia Belluz) 1:05:49

24h ago1:05:49

1:05:49

Losing weight should be simple: eat less, exercise more. But according to author and health journalist Julia Belluz, it's complicated. Listen as Belluz talks with EconTalk's Russ Roberts about her new book, Food Intelligence. Belluz argues that a calorie is pretty much a calorie whether it's carbs or fat. Keeping calories under control is often har…

1
Meta CMO: How Advertising Works Under the Hood 1:02:52

6d ago1:02:52

1:02:52

Ads pay for the internet—and they’re about to change again. a16z General Partner Erik Torenberg, entrepreneur and author Antonio García Martínez, and Meta CMO Alex Schultz dive into growth and performance marketing, privacy myths, retail media, and the AI future of “audience-of-one” advertising—plus Instagram what-ifs, WhatsApp as a super-app, and …

1
The Common Thread of All Technology: Monitoring the Situation, Ep.1 1:00:02

8d ago1:00:02

1:00:02

Announcing our new show, Monitoring the Situation, hosted by a16z General Partners Erik Torenberg and Katherine Boyle, with guest Eddie Lazzarin, CTO of a16z crypto. In this first episode, we ask how American Dynamism, consumer, games, and crypto all fit together, from Palmer/Oculus to Marc Andreessen’s Techno-Optimist Manifesto, while also explori…

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#999 - 21 Lessons from 999 Episodes - Naval Ravikant, Roger Federer & Vincent van Gogh 1:55:05

8d ago1:55:05

1:55:05

To celebrate 999, almost 1000, episodes of Modern Wisdom, I broke down some of my favourite lessons, insights and quotes from the last hundred episodes. Expect to learn how 999 episodes of Modern Wisdom have reshaped my understanding of happiness, success and relationships, what i've learned on losing points from Naval Ravikant & Roger Federer, the…

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Richard Sutton – Father of RL thinks LLMs are a dead end 1:06:22

4d ago1:06:22

1:06:22

Richard Sutton is the father of reinforcement learning, winner of the 2024 Turing Award, and author of The Bitter Lesson. And he thinks LLMs are a dead end. After interviewing him, my steel man of Richard’s position is this: LLMs aren’t capable of learning on-the-job, so no matter how much we scale, we’ll need some new architecture to enable contin…

1
The Great A.I. Build-Out + H-1B Visa Chaos + TikTok Braces for the Rapture 52:41

9d ago52:41

52:41

This week, an eye-popping $100 billion deal between OpenAI and Nvidia — along with an announcement about the construction of five new American data centers — has us re-examining our predictions of an A.I. bubble. Then, we try to make sense of the Trump administration’s changes to the H-1B visa program, which generated mixed reactions from tech lead…

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From Vibe Coding to Vibe Researching: OpenAI’s Mark Chen and Jakub Pachocki 52:05

10d ago52:05

52:05

What comes after vibe coding? Maybe vibe researching. OpenAI’s Chief Scientist, Jakub Pachocki, and Chief Research Officer, Mark Chen, join a16z general partners Anjney Midha and Sarah Wang to go deep on GPT-5—how they fused fast replies with long-horizon reasoning, how they measure progress once benchmarks saturate, and why reinforcement learning …

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#998 - Zack Telander - Everything You Want Is On The Other Side Of Cringe 1:47:33

10d ago1:47:33

1:47:33

Zack Telander is a musician, weightlifter, coach & YouTuber. Why are we so afraid of being cringe? If being cringe online is the price of success, why don’t more people pay it? So how do you train yourself past criticism and actually do what needs to be done in your life, whether people are watching you or not? Expect to learn why getting over bein…

1
Cognition’s CEO on What Comes After Code 53:22

11d ago53:22

53:22

The future has a way of showing up early to some places. In software engineering, one of those places is Cognition—the startup that made headlines in early 2024 with Devin, the world’s first autonomous coding agent, and more recently with its acquisition of the AI code editor Windsurf. Scott Wu, Cognition’s cofounder and CEO, has a front-row seat t…

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Cognition’s CEO on What Comes After Code 53:21

7d ago53:21

53:21

The future has a way of showing up early to some places. In software engineering, one of those places is Cognition—the startup that made headlines in early 2024 with Devin, the world’s first autonomous coding agent, and more recently with its acquisition of the AI code editor Windsurf. Scott Wu, Cognition’s cofounder and CEO, has a front-row seat t…

1
Software finally eats services - Aaron Levie 59:33

11d ago59:33

59:33

Should the US put a price on H-1B visas, or would that block the flow of new talent? Are AI coding agents actually making teams way more productive, or is it just hype? And in the AI platform shift, will the big winners be incumbents or new AI-native startups? Erik Torenberg is joined by Box co-founder and CEO Aaron Levie, a16z board partner Steven…

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Uncapped #25 | Lulu Cheng Meservey 50:18

6d ago50:18

50:18

Lulu Cheng Meservey is the leading voice in the new age of PR and comms and is the founder of Rostra, an advisory firm helping founders go direct. Lulu has been a trusted voice for founders like Palmer Luckey at Anduril, Eric Glyman at Ramp, and Brian Armstrong at Coinbase. She previously ran corporate affairs and communications for Activision Bliz…

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America's Autism Crisis and How AI Can Fix Science with NIH Director Jay Bhattacharya 58:13

12d ago58:13

58:13

Dr. Jay Bhattacharya is one of the country’s top medical experts and a 24-year professor of medicine at Stanford. After being censored and deplatformed during COVID for his role in opposing harsh lockdowns, he was appointed Director of the National Institutes of Health by President Trump in 2025. a16z General Partners Erik Torenberg, Vineeta Agarwa…

1
Steven Pinker on Common Knowledge 1:23:20

8d ago1:23:20

1:23:20

Why are Super Bowl ads so good for launching certain kinds of new products? Why do we all drive on the same side of the road? And why, despite laughing and crying together, do we often misread what others think? According to bestselling author and Harvard psychologist Steven Pinker, it all comes down to common knowledge, or the phenomenon that happ…

1
Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government vs. China 1:40:00

13d ago1:40:00

1:40:00

Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip race. To make sense of it all, Erik Torenberg is joined by Dylan Patel, chief analyst at SemiAnalysis, joins Sarah Wang, general partner at a1…

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#997 - Bonnie Blue & Louise Perry - The Modern Sex Work Debate 2:13:37

13d ago2:13:37

2:13:37

Louise Perry is a writer, Press Officer for the campaign group We Can’t Consent To This and an author. Bonnie Blue is a British pornographic actress and online content creator. Louise is the author of The Case Against The Sexual Revolution and Bonnie is the world’s most extreme example of the sexual revolution in action, so I figured it might make …

1
Charlie Kirk and the Rise of Political Violence 23:39

14d ago23:39

23:39

In this episode of Honestly with Bari Weiss, we share a special conversation featuring a16z general partner Katherine Boyle in the wake of Charlie Kirk’s shocking assassination. Katherine reflects on what courage means in a culture where words and debate are increasingly met with violence. Drawing on faith, history, and her own response to recent t…

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#996 - Stephen J. Shaw - Why Population Collapse is Closer Than You Think 2:53:10

15d ago2:53:10

2:53:10

Stephen J. Shaw is a data scientist and filmmaker. Birth rates in Western countries are collapsing, a trend even Elon Musk calls an existential threat. But what’s the true cause? Is it economics, fear of the future, cultural shifts, or something deeper? And more importantly, can anything actually reverse the decline? Sponsors: See me on tour in Ame…

1
Charlie Kirk and Online Rage + Inside Trump’s Chip Flip + This Week in A.I. 1:13:47

16d ago1:13:47

1:13:47

This week, we discuss the assassination of Charlie Kirk, freedom of speech and the terrifying new reality of extremely online violence. Then The Times’s David Yaffe-Bellany brings us inside the blockbuster New York Times investigation into a $2 billion investment in Trump’s crypto company World Liberty Financial and a controversial deal to send the…

1
Uncapped #24 | Balaji Srinivasan 50:53

14d ago50:53

50:53

Balaji Srinivasan is an angel investor, tech founder, and WSJ bestselling author of The Network State. He is currently the founder of The Network School, a frontier community for techno-optimists. Formerly the CTO of Coinbase and General Partner at Andreessen Horowitz, he is an early investor in many successful tech companies, including Anduril, Pe…

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#995 - Lionel Page - Born to Lie: How Humans Deceive Ourselves & Others 1:43:13

17d ago1:43:13

1:43:13

Lionel Page is a professor at the University of Queensland and an author. Why is human communication so complicated? For something we rely on every day, you’d think it would be simple, but language, tone, and context make it one of the most complex skills we have. So what makes communication so difficult, and what are some practical ways to get bet…

1
One Developer Got Thousands of Users Before His App Launched 57:24

18d ago57:24

57:24

Naveen Naidu built an app that found product-market fit backwards.Most apps launch first and then try to find users. Monologue, Naveen’s AI voice dictation app that came out of beta yesterday, did the opposite. It built a following of thousands of users during its incubation period at Every—many of them switching over from venture capital-backed co…

1
One Developer Got Thousands of Users Before His App Launched 57:25

18d ago57:25

57:25

Naveen Naidu built an app that found product-market fit backwards. Most apps launch first and then try to find users. Monologue, Naveen’s AI voice dictation app that came out of beta yesterday, did the opposite. It built a following of thousands of users during its incubation period at Every—many of them switching over from venture capital-backed c…

1
The Death of Search: How Shopping Will Work In The Age of AI 45:22

18d ago45:22

45:22

The web is unhealthy, and AI agents are about to rewrite how we shop. In this episode, a16z General Partner Alex Rampell and Partner Justine Moore explore how AI agents will change commerce and the implications for Google’s business model, affiliate marketing, online shopping, and more. Timecodes: 0:00 Introduction 0:12 The Role of AI Agents in Com…

1
How OpenAI Built Its Coding Agent 1:20:12

19d ago1:20:12

1:20:12

OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software? In this episode, General Partner Anjney Midha goes behind the scenes with one of Codex’s product leads- Alexander Embiricos - to unpack its origin story, why its PR success ra…

1
How Did America Build the Arsenal of Democracy? (with Brian Potter) 1:05:05

20d ago1:05:05

1:05:05

American manufacturing of aircraft during WWII dwarfed that of its enemies. By the end of the war, an American assembly line was producing a B-24 bomber in less than an hour. But that success was far from inevitable. Structural engineer and writer Brian Potter speaks with EconTalk's Russ Roberts about the logistical challenges of ramping up product…

1
Faster Science, Better Drugs 56:26

20d ago56:26

56:26

Can we make science as fast as software? In this episode, Erik Torenberg talks with Patrick Hsu (cofounder of Arc Institute) and a16z general partner Jorge Conde about Arc’s “virtual cells” moonshot, which uses foundation models to simulate biology and guide experiments. They discuss why research is slow, what an AlphaFold-style moment for cell bio…

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#994 - Sam Sulek - The Endless Pursuit of Progress 2:10:19

20d ago2:10:19

2:10:19

Sam Sulek is a professional bodybuilder and YouTuber. From zero to millions of fans, Sam Sulek’s rise has been nothing short of explosive. In just a few years, he’s become one of social media’s most-watched and talked-about creators. Sit back as we dive into the story of the man behind some of the internet’s most beloved vlogs, fueled by hefty scoo…

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#993 - Katie Herzog - A Controversial New Cure for Alcohol Dependence 1:35:35

22d ago1:35:35

1:35:35

Katie Herzog is a journalist, podcaster, and writer. What does it take to get sober in today’s world? From traditional paths like AA to the grit of going cold turkey, the old methods of sobriety may no longer be enough. But what if counterintuitive, cutting-edge approaches, backed by modern science, offer new ways to manage alcohol use? And what do…

1
Fully autonomous robots are much closer than you think – Sergey Levine 1:28:28

18d ago1:28:28

1:28:28

Sergey Levine, one of the world’s top robotics researchers and co-founder of Physical Intelligence, thinks we’re on the cusp of a “self-improvement flywheel” for general-purpose robots. His median estimate for when robots will be able to run households entirely autonomously? 2030. If Sergey’s right, the world 5 years from now will be an insanely di…

1
Are We Past Peak iPhone? + Eliezer Yudkowsky on A.I. Doom 1:12:24

23d ago1:12:24

1:12:24

Apple’s yearly iPhone event took place this week, and it left us asking, Is Apple losing the juice? We break down all the new products the company announced and discuss where it goes from here. Then, Eliezer Yudkowsky, one of the most fascinating people in A.I., has a new book coming out: “If Anyone Builds It, Everyone Dies.” He joins us to make th…

1
Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy 1:35:38

23d ago1:35:38

1:35:38

In this conversation from Lenny’s Podcast, Ben Horowitz joins Lenny to discuss the psychological muscle every founder needs, why hesitation can be fatal for CEOs, when it’s time to replace a founder, and how to normalize failure while building confidence. They also explore the Databricks founding story, investing in Adam Neumann after WeWork, wheth…

1
Inside the $13T Mortgage Machine 54:48

24d ago54:48

54:48

The $13T U.S. mortgage market serves 50M homeowners but still runs on decades-old software. In this episode, a16z GP Angela Strange hosts Tim Mayopoulos (ex-CEO of Fannie Mae and ex-president of Blend), Mike Yu (co-founder and CEO of Vesta), and Andrew Wang (co-founder and CEO of Valon) to unpack why standardization and regulation slow change, and …

1
#992 - Dr Sarah Hill - The Period Brain: How Hormones Change Women’s Behaviour 1:39:28

24d ago1:39:28

1:39:28

Dr Sarah Hill is a professor at TCU, a research psychologist, expert in women’s hormones and brain science, and an author. Each month, women experience hormonal changes that go far beyond the clichés of PMS. These shifts can influence mood, stress response, and even how women relate to others. So how can recognizing these patterns make it easier fo…