Welcome to PathPulse: Pathology Innovators in Action, your go-to podcast for practical and implemented digital pathology insights and solutions. This podcast is sponsored by the Digital Diagnostic Summit and Lumea. www.lumeadigital.com
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Digital Diagnostic Summit Podcasts
Aleksandra Zuraw from Digital Pathology Place discusses digital pathology from the basic concepts to the newest developments, including image analysis and artificial intelligence. She reviews scientific literature and together with her guests discusses the current industry and research digital pathology trends.
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172: Why Structured Reporting Is the Future of Pathology | mTuitive on Workflow, Data & Compliance with Peter O'Toole
37:45
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37:45Send us a text If your pathology reports and other data could talk, what would they say about the future of precision medicine? The truth is, most labs already have the data—they’re just not having a conversation with it. In this episode, I talk with Peter O’Toole, President and Chief Software Architect at mTuitive. We recorded live at Pathology Vi…
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171: Real-World Digital Readiness: Turning Stains into Reliable Scans
22:58
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22:58Send us a text Is your lab truly digitally ready—or just scanning slides? That’s the question I unpack in this live discussion from Day 2 of SITC’s 40th Anniversary Meeting, joined by David Anderson (Biocare Medical) and Don Ariyakumar (Hamamatsu Photonics). Together, we explore what digital readiness really means for multiplex immunofluorescence (…
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170: Inside SITC 2025: How Multiplex IF Is Changing Cancer Care
22:50
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22:50Send us a text Can spatial biology and multiplex immunofluorescence truly transform how we understand cancer? I went live from the Society for Immunotherapy of Cancer (SITC) 2025 — the 40th Anniversary Meeting to explore how spatial biology, multiplex IF, and digital pathology are coming together to redefine cancer diagnostics, research, and precis…
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169: AI Across Organ Systems: Kidney, Liver, Colon, Bladder, and Beyond
37:50
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37:50Send us a text Can one AI system learn from every organ — and teach us something new about all of them? In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before. Fr…
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How Digital Platforms are Transforming Pathology Education - with Kamran Mirza
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32:44Get ready for an insightful conversation on how digital platforms are revolutionizing pathology education. In this episode of PathPulse, host James Thackeray welcomes a true trailblazer, Dr. Kamran Mirza, Professor of Pathology and Assistant Chair for Education at Michigan Medicine. Dr. Mirza shares his unique global perspective and passion for mak…
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168: Smarter Slides: How AI Is Reshaping Kidney, Thyroid & GI Pathology
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25:55Send us a text If artificial intelligence can match—or even surpass—our diagnostic accuracy, what happens to the role of the pathologist? That’s the question I explore in this episode of DigiPath Digest #30, where I break down three fascinating papers showing how AI is changing the way we diagnose, classify, and predict outcomes in renal transplant…
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167: Why Accuracy Matters in Digital Pathology Podcast with Keith Wharton, Jr.
1:36:35
1:36:35
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1:36:35Send us a text Why do some pathologists still hesitate to trust digital slides—even after the FDA says “yes”? Because accuracy in digital pathology isn’t just about pixels—it’s about precision, validation, and confidence. In this episode, I talk with Dr. Keith Wharton, MD, PhD, Global Medical Director at Roche Diagnostics, about how the Roche Digit…
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166: Future of Pathology AI, Training & The Next Generation of Diagnostics
28:51
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28:51Send us a text Live from Pathology Visions 2025 in San Diego, I share highlights from Day 2 of the world’s leading digital pathology conference, where experts explored how AI, empathy, and training are shaping the next generation of pathologists. This episode captures the shift from technology as a tool to technology as a bridge — helping us connec…
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165: How AI Is Changing Cancer Diagnosis Insights from PathVision 2025
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22:15By Aleksandra Zuraw, DVM, PhD
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164: What Happens to Human Expertise When AI Takes Over in Medicine
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53:52Send us a text Will AI make doctors and specialists less skilled—or even replace them? That’s the question I explore in this episode of DigiPath Digest #29. As someone working where AI meets digital pathology, I’m both excited and cautious about how automation shapes our skills and professional identity. In this episode, I discuss two studies that …
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163: Digital Diagnostics Summit 2025 Innovation in Action - Conference Update
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30:11Send us a text What if climbing the digital pathology “mountain” isn’t about reaching the summit alone—but knowing where base camp is, and who you bring with you? In this episode, I take you inside the Digital Diagnostic Summit in Park City, hosted by Lumea, where fewer than 100 digital pathology leaders gathered to share their journeys, challenges…
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Navigating the Full Digital Transformation in Pathology - with Syed Hoda
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27:08In this episode of PathPulse, we're joined by Dr. Syed Hoda, a self-described ordinary pathologist who faced an extraordinary challenge. With no prior experience in informatics or digital pathology, Dr. Hoda was tasked with spearheading the transition to a fully digital workflow at NYU Langone. His mission was to create a real, functional system fo…
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162: How Color Impacts Every Diagnosis |Color Calibration in Digital Pathology w/ Tom Kimpe (Barco) and Monika Lamba Saini
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1:25:43Send us a text What if up to 35% of the diagnostic color data on your pathology slides never reaches your eyes—just because of your monitor? In this episode, sponsored by Barco, I sit down with Dr. Monika Lamba Saini (ADC Therapeutics) and Tom Kimpe (Barco) to uncover why color calibration in digital pathology isn’t optional anymore—it’s critical f…
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161: 7 Secrets to Smarter AI in Cancer Care | Lessons from NCCN Summit
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35:30Send us a text 7 Counterintuitive Secrets from NCCN’s 2025 AI in Cancer Care Summit When the National Comprehensive Cancer Network (NCCN) gathers healthcare leaders, people listen. I attended the 2025 Policy Summit on the evolving AI landscape in cancer care—and walked away with insights that were raw, practical, and surprisingly hopeful. Instead o…
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160: AI in Medicine: Neuropathology, Renal Disease, Hematology & Cytology
25:14
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25:14Send us a text What if the way we quantify pathology is more guesswork than science? In this episode of DigiPath Digest, I take you through the latest research where AI is not just supporting but challenging traditional methods of image analysis in neuropathology, nephrology, hematology, and cytology. From Boston brain banks to Mayo Clinic kidney m…
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159: What If Your AI Tool Is Lying: Hidden Bias in Pathology Algorithms
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27:49Send us a text What if the AI tools we trust for cancer diagnosis are not always correct? This episode of DigiPath Digest takes on the uncomfortable but critical question: can AI “lie” to us—and how do we verify its performance before adopting it in clinical practice? Highlights: [00:02:00] Foundation models in action: Deployment of a fine-tuned pa…
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158: Multimodal Magic AI’s Role in Lung & Prostate Cancer Predictions
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28:50Send us a text What if AI could predict cancer outcomes better than traditional methods—and at a fraction of the cost? In this episode, I explore how multimodal AI is reshaping lung and prostate cancer predictions and why integration challenges still stand in the way. Episode Highlights with Timestamps: [00:02:57] Agentic AI in toxicologic patholog…
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From Hurdles to Horizons: The Complex Journey of Adopting Digital Pathology in U.S. Hospitals - with Orly Ardon
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28:01Welcome to PathPulse, the Digital Diagnostic Podcast! In this episode, your host, James Thackeray, speaks with a true trailblazer in the field: Dr. Orly Ardon. Get ready to dive deep into the fascinating and complex journey of adopting digital pathology in the US hospital market. Transcript: https://lumeadigital.com/adopting-digital-pathology-in-us…
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157: How Academic Pathology Programs Can Prepare for AI | UPMC Podcast
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38:52Send us a text “AI in Pathology Isn’t Coming — It’s Already Here. Are You Ready?” From confusion to clarity — that’s what this episode is all about. I sat down with Drs. Liron Pantanowitz, Hooman Rashidi, and Matthew Hanna to dissect one of the most important and comprehensive AI-in-pathology resources ever created: the 7-part Modern Pathology seri…
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156: Digital Pathology and AI in Cancer Grading, T-Cell Imaging & Biomarkers
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34:35Send us a text Can AI Grade Cancer Better Than Us? The Truth About T-Cell Imaging, Biomarkers & Digital Pathology Disruption You think Saturday mornings are for coffee? Try diving into bone marrow morphology, organ donor kidney biopsies, and AI-driven metastasis detection at sunrise. That’s how I do it—and you’re invited to join. Welcome to another…
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155: AI Pathology & Genomics_ A New Benchmark for Predicting Gene Mutations
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23:26Send us a text AI Pathology & Genomics: A New Benchmark for Predicting Gene Mutations If you still think visual quantification is “good enough” in pathology, think again. In this 27th episode of DigiPath Digest, I break down four transformative abstracts that show how AI is shifting our diagnostic landscape—from breast cancer segmentation to fibros…
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154: AI in Pathology: Advances in Prostate, Bladder & Endocrine Cancer
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20:43Send us a text If our visual scoring is still based on gut feeling, how do we scale precision? In this week’s DigiPath Digest, I explored four new AI-focused papers that could reshape how we diagnose prostate, bladder, gastroesophageal, and endocrine cancers. From automated IHC scoring to predicting urethral recurrence post-cystectomy, these studie…
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153: Can GPT-4o Classify Tumors Better Than Us? AI-Powered Pathology Insights
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19:43Send us a text If we don’t learn to work with LLMs now, we might end up competing with them. 🧠 In this week’s DigiPath Digest, I return to our Journal Club to unpack the latest research on AI in tumor classification, focusing on GPT-4o, LLaMA, and other LLMs. Can these models really outperform traditional tools when analyzing pathology reports? Sur…
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152: AI in Pathology, ML-Ops, and the Future of Diagnostics – 7-Part Livestream 7/7
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42:46Send us a text AI in Pathology: ML-Ops and the Future of Diagnostics What if the most advanced AI models we’re building today are doomed to die in the machine learning graveyard? 🤯 That’s the haunting question I tackled in the final episode of our 7-part series exploring the Modern Pathology AI publications. In this session, I explored machine lear…
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151: Ethics and Bias Considerations in AI – 7-Part Livestream 6/7
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42:00Send us a text Can We Ever Eliminate Bias in AI for Pathology? Every time we think we’ve trained a “neutral” algorithm, we discover our own fingerprints all over it. Our biases. Unconscious. Systemic. Data-driven. And if we ignore them, AI won’t just fail—it will fail patients. Welcome back, my digital pathology trailblazers! In this sixth episode …
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150: AI in Pathology – Regulatory Aspects of AI – 7-Part Livestream 5/7
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42:29
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42:29Send us a text The Most Overlooked Risk in AI for Pathology? It’s Not What You Think… Welcome, my trailblazing digital pathologists! In this episode, I dive headfirst into the regulatory maze of Artificial Intelligence (AI) in pathology, covering global frameworks, safety risks, ethics, and the future of software as a medical device. While regulati…
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149: AI in Pathology: From Pixels to Patients with Dr. Anil Parwani
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39:40Send us a text In this episode sponsored by Epredia, Dr. Anil Parwani explores the transformative journey of digital pathology from basic slide scanning to AI-driven diagnostics. He shares real-world implementation experiences and demonstrates how these technologies are addressing critical challenges in pathology practice. Pathology faces increasin…
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148: Statistics of Generative and Non-Generative AI – 7-Part Livestream 4/7
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36:24Send us a text You might be using AI models in pathology without even knowing if they’re giving you reliable results. Let that sink in for a second—because today, we’re fixing that. In this episode, I walk you through the real statistics that power—and sometimes fail—AI in digital pathology. It's episode 4 of our AI series, and we’re demystifying t…
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147: Non-Generative AI – Predictive Analytics & ML – 7-Part Livestream 3/7
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44:20Send us a text What if I told you the biggest AI breakthroughs in pathology aren’t coming from ChatGPT or generative tools—but from the quiet power of predictive analytics and machine learning? In this episode, I explore the non-generative side of artificial intelligence in pathology. These are the tools that detect tumors, segment tissue, classify…
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146: Generative AI – Deeper Dive – 7-Part Livestream 2/7
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53:22Send us a text ❗️Is synthetic data trustworthy enough to train AI for patient care? It just might be—and that's what both excites and terrifies me. ❗️ Hey trailblazers! In this episode of the Digital Pathology Podcast, I take you through the second part of our AI in Pathology series—this time, we’re focusing on generative AI and how it’s revolution…
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145: The Role of Generative vs Non-Generative AI in Medical Diagnostics – 7-Part Livestream 1/7
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1:15:59Send us a text Generative vs. Non-Generative AI in Pathology: Why the Difference Matters If we don’t start defining what kind of AI we’re talking about, we risk letting buzzwords replace real science. 🧠 This is where we begin—at the foundation. Welcome to the first episode of our 7-part Guided Journey through AI in Pathology, inspired by two must-r…
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144: Court Halts FDA Rule on Lab-Developed Tests: What It Means for Pathology
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9:48Send us a text Will FDA rules disrupt the way we diagnose diseases? In this episode, I break down a seismic shift in lab medicine: a federal court has vacated the FDA’s controversial rule classifying lab-developed tests (LDTs) as medical devices. This change carries serious implications for innovation, digital pathology, AI-based diagnostics, and s…
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Digital Pathology Tech: What Pathologists Really Want - with Imogen Fitt
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31:05Step into the evolving landscape of diagnostics with this insightful episode of PathPulse, the Digital Diagnostic Podcast! Host Andy Ivie, Chief Innovation Officer at Lumea and board member of the Digital Diagnostic Summit, sits down with Imogen Fitt, a principal analyst at Signify Research and a leading voice in healthcare technology market analys…
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143: Modular Scanners, Cytology, and AI Integration in Digital Pathology
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43:36Send us a text You think going digital in pathology just means buying a scanner? Think again. In this episode sponsored by Epredia, I sat down with Ryan Davis, Director of Global Business Strategy at Epredia, to talk about what it really takes to implement digital pathology—and why modularity, cytology support, and AI integration are changing the g…
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142. First All-in-One Digital Pathology Tool: Techcyte's Fusion Platform to Improve Pathologists' Workflow and Integrate AI.
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35:14Send us a text In this episode, I talk with Tiffany Chen, MD, and Ben Cahoon from Techcyte about Fusion, their new digital pathology platform. Fusion integrates clinical and anatomic pathology workflows, AI algorithms, and electronic health records—all into one streamlined experience. We explore how Fusion simplifies case management, improves diagn…
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Pathology in Motion: A Young Pathologist's Journey into Digital Diagnostics and Social Media Education - with Melanie Bourgeau
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10:04Get ready for an inspiring episode of PathPulse, the Digital Diagnostic Podcast! This month's host, David Dalton, sits down with Dr. Melanie Bourgeau, a surgical pathology fellow at the University of Florida, as they explore the exciting intersection of pathology, digital innovation, and social media outreach. In this conversation, Dr. Bourgeau sha…
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141: Digital Pathology Tools: How To Get Them FDA Approved?
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18:55Send us a text Why do so many digital pathology tools stall before they ever reach patients? In this USCAP 2025 special sponsored by Muse Microscopy, I talk with Esther Abels, founder of SolarisRTC, regulatory strategist, and the force behind the first FDA-cleared whole slide imaging system. We break down what startups and established companies mus…
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140: How Are Pathologists in Japan Using AI and Digital Tools? Podcast with Dr. Robert Osamura
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24:18Send us a text Can you still call it “digital transformation” if you’re scanning slides and still tethered to glass? This special episode, recorded at USCAP and sponsored by MUSE Microscopy, features Dr. Robert Osamura from Japan. We explore how digital pathology is being implemented across Japanese hospitals, how regulations shape adoption, and wh…
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Precision at the Point of Diagnosis: The Role of Genomic Tests in Personalized Pathology - with Jay Jhaveri
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29:27Step into the future of diagnostics with this enlightening episode of PathPulse, the Digital Diagnostic Podcast! Host James Thackeray welcomes Jay Jhaveri, Senior Director at Pacific Edge Cancer Diagnostics, to unravel the profound impact of genomic testing on personalized pathology. Jay Jhaveri brings a unique blend of extensive clinical backgroun…
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139: Why AI Won't Replace Pathologists and How It Can Help Them Thrive
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20:24Send us a text Why are so many pathologists still afraid of going digital? In this USCAP special episode sponsored by Muse Microscopy, I talk with Dr. Sarah Dry, Chair of Pathology and Laboratory Medicine at UCLA, about real-world adoption, AI fear, and how change is best managed when it's people-led. From her early digital research lab in 2007 to …
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138: Future of Pathology Across Continents Podcast with Dr. Junya Fukuoka and Dr. Norman Zerbe
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8:57Send us a text Why is digital pathology progressing faster in some parts of the world than others? In this international episode sponsored by Muse Microscopy, I sit down with Junya Fukuoka and Norman Zerbe—presidents of the Asian and European Societies of Digital Pathology—to unpack how cultural, regulatory, and infrastructural forces are shaping p…
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137: What’s Driving Digital Pathology Forward? | Insights from PathVisions 2024
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22:13Send us a text At the last Pathology Visions 2024, I sat down with Imogen Fitt of Signify Research and Nick Best from Pathology News for a candid, energetic recap of what’s really shaping the future of digital pathology. We discuss how two pathologists drove digital pathology adoption in their lab, the reality behind radiology partnerships, the cau…
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136: Trends in Digital Pathology and AI Integration | Podcast with Alae Kawam, DO, FCAP
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11:51Send us a text “It used to take 40 minutes, now it takes 15” - this is what Dr. Alae Kawam said about her AI-powered prostate biopsy evaluation workflow. In this energizing episode of the Digital Pathology Podcast recorded at PathVisions 2024, Dr. Alae Kawam joins me to reflect on where pathology is headed—from AI-assisted prostate diagnostics to d…
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135: Inside the Asian Society of Digital Pathology | Podcast with Junya Fukuoka, MD, PhD
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25:26Send us a text What does it take to build a digital pathology movement across the most diverse region on Earth? In this episode of the Digital Pathology Podcast, I’m joined by Dr. Junya Fukuoka, practicing pathologist, educator, and founder of the Asian Society of Digital Pathology (ASDP). From Japan to India, Saudi Arabia to South Korea, Asia’s di…
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134: AI Trust Issues, Challenges, and Multimodal Insights in Pathology with Hamid R. Tizhoosh, PhD
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1:39:23Send us a text In this episode, I’m joined by Dr. Hamid Tizhoosh, professor of biomedical informatics at the Mayo Clinic, to unravel what’s truly holding back AI in healthcare, especially pathology. From the myths of general-purpose foundation models to the missing link of data availability, this conversation explores the technical and ethical real…
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133: The World Tumor Registry A Global Resource for Pathology and Patient Care
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48:03Send us a text In this episode of the Digital Pathology Podcast, I sit down with Dr. Yuri Nikiforov, founder of the World Tumor Registry, to explore how this global, open-access whole slide image platform contributes to cancer diagnostics, education, and research. We talk about how the registry allows pathologists, researchers, and patients to view…
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132: Ethical and Bias Considerations in Artificial Intelligence/Machine Learning
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51:06Send us a text In this episode of the Digital Pathology Podcast, I explore the ethical and bias considerations in AI and machine learning through the lens of pathology. This is part six of our special seven-part series based on the landmark Modern Pathology review co-authored by the UPMC group, including Matthew Hanna, Liam Pantanowitz, and Hooman …
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Send us a text USCAP 2025 Daily Update – Day 3 Recap with Dr. Aleksandra Zuraw In this episode of the Digital Pathology Podcast, I bring you Day 3 insights live from USCAP 2025—from moderating the MUSE panel on slide-free imaging to exploring regulatory strategies, tech innovations, and collaborations across the digital pathology community. Get an …
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Send us a text USCAP 2025 Daily Update – Day 4 with Dr. Aleksandra Zuraw It’s the final day of USCAP 2025, and in this episode of the Digital Pathology Podcast, I’m sharing personal moments, spontaneous tech wins (and fails), and meaningful conversations with some of the most forward-thinking voices in digital pathology. From running around with mi…
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From Diagnosing to Disrupting: A Pathologist’s Leap into Innovation - with Matt Leavitt
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43:54Join us on PathPulse, the Digital Diagnostic Podcast, as we delve into the groundbreaking journey of Dr. Matthew O. Leavitt, a Stanford-trained pathologist and visionary leader in digital pathology. Host James Thackeray sits down with Dr. Leavitt to uncover his relentless pursuit of leveraging digital technologies to revolutionize patient care, par…
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