Hear from scientists working to develop new vaccines and understand immunity to microbial pathogens. Host: Larissa Thackray, Ph.D., Professor of Infectious Diseases
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CVIMP Podcasts
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Episode 20: Understanding broadly protective immune responses to develop pandemic virus vaccines
23:37
23:37
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23:37We talk with Dr. Anass Abbad, a postdoctoral fellow in the Department of Microbiology at the Icahn School of Medicine Mount Sinai, NY who studies humoral immune responses and virus-host receptor interactions to design next generation pandemic virus vaccines.By CVIMP
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Episode 19: Using structural immunology to understand protective or pathogenic antibodies
21:14
21:14
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21:14We talk with Dr. Sandhya Bangaru, a staff scientist in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute, CA who uses advances in cryo-EM to understand antibody epitopes important for their antiviral protective activity and their pathogenic activity in allergic diseases.…
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Episode 18: Understanding B cell responses to natural infection to design better vaccines
15:46
15:46
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15:46We talk with Dr. Florian Krammer, the endowed Mount Sinai Professor of Vaccinology at the Icahn School of Medicine, New York, NY and Director of the Ludwig Boltzmann Institute for Science Communication and Pandemic Preparedness at the Medical University of Vienna, Austria, who studies the B cell response in the context of natural infection to bette…
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Episode 17: Using a rodent hepacivirus to uncover a role for iHALT during HCV infection
19:18
19:18
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19:18We talk with Dr. John Gridley, a postdoctoral fellow in the Vaccinology Training Program at Emory University, GA, who uses a hepatitis C virus-related rodent hepacivirus model to identify correlates of protective immunity for HCV and the role of inducible Hepatic-Associated Lymphoid Tissue (iHALT) in the induction of this immune response.…
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Episode 16: Creating healthy local communities to foster local to global impact
15:59
15:59
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15:59We talk with Dr. Sandro Galea, Dean and Professor of the School of Public Health at Washington University in St. Louis, who uses population based sciences to promote health locally and globally.By CVIMP
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Episode 15: Understanding B cell immune responses and memory to guide vaccine design
21:51
21:51
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21:51By CVIMP
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Episode 14: Using Reverse Vaccinology 3.0 for Pandemic Preparedness
15:48
15:48
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15:48We talk with Dr. Emanuele Andreano, Head of Serology and Immunology at Fondazione Biotecnopolo di Siena, Italy, who combines immunology, structural biology and artificial intelligence to rapidly develop novel monoclonal antibodies therapies and antiviral vaccine targets.By CVIMP
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Episode 13: Using structure-based design to develop novel antiviral therapeutics
25:22
25:22
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25:22We talk with Dr. Daniel Wrapp, Assistant Professor Assistant Professor at the Duke Human Vaccine Institute at Duke University School of Medicine, NC, who uses structure-based design to develop novel therapeutic interventions against viruses.By CVIMP
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Episode 12: Complex carbohydrates - targets for a Klebsiella pneumoniae vaccine
24:47
24:47
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24:47We talk with Dr. Paeton Wantuch, a Staff Scientist in the Department of Pediatrics at Washington University School of Medicine, MO, who uses animal models to understand correlates of protection for vaccines against Klebsiella pneumoniae.By CVIMP
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Episode 11: Mapping RSV evolution to infection and monoclonal antibody treatments
21:10
21:10
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21:10We talk with Dr. Cassie Simonich, Pediatric Infectious Diseases Fellow at the University of Washington, WA, who uses RSV pseudoviruses and deep mutational scanning approaches to define the evolution of the RSV fusion protein to escape natural or vaccine-induced immunity and monoclonal antibody treatments.…
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Episode 10: Designing a pipeline to enhance T cell-mediated vaccine protection
17:06
17:06
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17:06We talk with Dr. Alba Grifoni, Research Assistant Professor scholar in the Center for Vaccine Innovation at the La Jolla Institute for Immunology, CA, who uses bioinformatic analyses and immune focusing approaches to improve protective T cell responses induced by vaccines.By CVIMP
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Episode 9: Using mosaic nanoparticle vaccines to generate broadly protective immmune responses
33:42
33:42
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33:42We talk with Dr. Alexander Cohen, Postdoctoral Scholar in the Division of Biology and Biological Engineering at the California Institute of Technology, CA, who uses immune focusing approaches to design vaccines that generate antibodies against conserved epitopes on viral antigens.By CVIMP
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Episode 8: Using comparative immunology to design better vaccines
18:39
18:39
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18:39We talk with Dr. Hanover Matz, Postdoctoral Research Associate in Pathology and Immunology at Washington University School of Medicine, MO, who uses human vaccine studies as well as comparisons to other vertebrate immune systems to understand how adaptive immunity has evolved and how we can use that information to generate more effective vaccines.…
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Episode 7: Novel approaches to dissect antibody responses to respiratory viruses
30:13
30:13
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30:13We talk with Dr. Seth Zost, Research Instructor in the Vanderbilt Vaccine Center at Vanderbilt University Medical Center, TN, who is developing new approaches to define how antibody responses to SARS-CoV-2 and influenza viruses shape the antigenic evolution of these viruses.By CVIMP
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Episode 6: Using phylogenetic inference to design vaccine antigens
27:50
27:50
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27:50We talk with Dr. Brett Case, Instructor of Infectious Diseases at Washington University School of Medicine, MO, who studies how to generate cross-protective and sterilizing mucosal immunity following vaccination.By CVIMP
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Episode 5: New therapeutic strategies for treating mycobacterium tuberculosis
22:13
22:13
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22:13We talk with Dr. Christina Stallings, Professor of Molecular Microbiology at Washington University School of Medicine, MO, who studies host molecules important for mycobacterium tuberculosis pathogenesis to develop new therapies to treat mycobacterium infection and disease.By CVIMP
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We talk with Dr. Robert Seder, Chief of the Cellular Immunology Section of the Vaccine Research Center in Bethesda, MD, who studies how changing the route of vaccination can improve immunity and protection against pathogens.By CVIMP
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Episode 3: Immunobiology of pregnancy and birth
20:26
20:26
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20:26We talk with Dr. Nardhy Gomez-Lopez, a professor at Washington University School of Medicine in St. Louis, MO, who studies the immunology of pregnancy and birth to identify biomarkers that may predict adverse outcomes.By CVIMP
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Episode 2: Evolution of antibodies in the germinal center
17:33
17:33
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17:33We talk with Dr. Gabriel Victora, an associate professor and HHMI investigator at The Rockefeller University in NY, NY, who studies how antibodies are generated in response to infection and immunization through the evolutionary process of affinity maturation in germinal centers.By CVIMP
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Episode 1: Respiratory viruses and maternal vaccines
19:36
19:36
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19:36We talk with Dr. Helen Chu, a physician and professor at the University of Washington in Seattle, WA, who studies the transmission of respiratory viruses in the community and correlates of immune protection induced by maternal vaccines against these viruses.By CVIMP
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