The Business of Biotech is the pod dedicated to leaders of emerging biopharma firms. SUBSCRIBE to our new newsletter at www.bioprocessonline.com/bob. We bring you insight into organizational, finance and funding, HR, clinical, manufacturing, regulatory, and commercial challenges you’ll face as you navigate your company from an idea to success in the clinic and beyond. Each episode features guest commentary and best practices from accomplished founders and biopharma industry luminaries. The B ...
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Ben Comer Podcasts
Essential film reviews, TV reviews, and all conversations around movie and non-movie related stuff brought to you by Mark Kermode and Simon Mayo. Plus a whole bunch of recommendations to watch in cinemas, on all streaming services and on physical media. Want more Kermode & Mayo? Subscribe to Kermode & Mayo’s Extra Takes to get ad-free listening plus access to our subscriber-exclusive show, TAKE TWO, with new episodes every Friday. Subscribe today on Apple Podcasts and Spotify, or at extratak ...
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The Empire Film Podcast is the official podcast of Empire, the world's biggest and best movie magazine. We bring you all the latest movie news and nonsense, as well as reviews of the week's new films, an assortment of irreverent, film-related chat and interviews with some of Hollywood's best and brightest. New episodes every Friday. For our famous deep dives into specific movies, subscribe to the Empire Spoiler Special Podcast at https://empire.supportingcast.fm/ Love TV? Subscribe to our si ...
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Life Science Connect Editors' Roundtable: Wrapping Up 2025 And Looking Ahead
1:21:12
1:21:12
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1:21:12We love to hear from our listeners. Send us a message. This week's special holiday episode of the Business of Biotech brings seven chief editors from the Life Science Connect family together to talk about the life sciences industry topics, trips, and reporting that mattered most in 2025, and what each editor has planned for 2026. From the RNA, cell…
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It's finally here! A little later than usual due to some technical mishaps, the latest episode of The Shameless Plug sees Chris Hewitt and Nick de Semlyen sit down on Teams (yes, Teams!) to have a chat about the latest issue of Empire magazine, which is still on sale in all good, evil, and virtual newsagents. In it, our dynamic duo talk about the c…
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The Empire Podcast Preview Of The Films Of 2026
1:36:41
1:36:41
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1:36:41With the Empire Podcast team still in hibernation until the first show of 2026 (our live show at Kings Place, London, on Jan 9 — check kingsplace.co.uk for last-minute tickets), we're plugging the gap where the regular podcast would usually be with something a little different: a look ahead to the films of 2026, in which Chris Hewitt, Helen O'Hara,…
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Building Cell Therapy Companies With Kenai Therapeutics' Nick Manusos
46:39
46:39
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46:39We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Nick Manusos, CEO at Kenai Therapeutics, talks about his experiences building cell therapy spinouts from FujiFilm Cellular Dynamics, learning from big pharma decision-making processes, and dosing the first patient with Kenai's allogeneic neuron…
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The Empire Podcast Review Of The Year 2025
2:41:08
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2:41:08And so, as 2025 disappears off into the distance, it's the most wonderful time of what's left of the year, as the Empire Podcast team get together in the podbooth for their marathon deep dive/look back at the cinematic year that was. Join Chris Hewitt, Helen O'Hara, and James Dyer for this near-three-hour behemoth in which they go through the year …
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Modernizing Clinical Trial Operations With Merck's Jennifer Sheller
55:39
55:39
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55:39We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Jennifer Sheller, SVP and Head of Global Clinical Trial Operations at Merck talks about simplifying trial protocols and what she likes about Merck's hybrid functional service provider model for conducting trials in over 60 countries. Jennifer s…
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It’s that time of year on the Take when Mark runs down his best and worst films of the year—so get ready for a reminder of 2025’s biggest raves and rants from I’m Still Here to Tron: Ares. It’s all new content as he ranks the big-screen bangers and clangers of the last 12 months and picks the Take’s best picture. We’ll also look at the year’s best …
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Good Kate Winslet (lass) Looks Back on her Feats of Acting
1:02:23
1:02:23
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1:02:23Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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Farewell, Rob (ft. guests Glenn Close; Stephen Lang; Josh Safdie)
2:13:59
2:13:59
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2:13:59The final Empire Podcast of the year is here, folks, and it's a bumper-sized jamboree, longer than usual and hopefully fit to tide you over until we return with Episode 700 (live from Kings Place) on January 11th. For the first time ever, the revolving fourth chair revolves wildly during the pod itself, so Chris Hewitt, Helen O'Hara, and James Dyer…
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It: Welcome To Derry — An Empire Podcast Special, In Association With Warner Bros.
46:38
46:38
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46:38They all float down here. Now that It: Welcome To Derry, the prequel to Andy Muschietti's It Chapter One and It Chapter Two, has finished its eight-episode run, the Empire Podcast has teamed up with Warner Bros. to bring you a special episode in which Chris Hewitt, Helen O'Hara, and James Dyer conquer their fears of clowns, spiders, and spider-clow…
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AVATAR: FIRE AND ASH: “like some nightmare furries convention”
1:32:40
1:32:40
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1:32:40Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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Transforming Chronic Kidney Disease With ProKidney's Bruce Culleton, M.D.
55:36
55:36
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55:36We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Bruce Culleton, M.D., CEO at ProKidney, talks about moving from academic research to industry and the role a key mentor played in his career path. Bruce discusses his experiences as a first-time CEO at ProKidney, a late-stage autologous cell th…
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Paul Thomas Anderson & Boogie Nights: An Empire Podcast Special, In Association With Warner Bros.
44:55
44:55
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44:55Boogie Nights wasn't Paul Thomas Anderson's first movie (that was Hard Eight), but it's the film that put him firmly on the map, and served notice that here was a serious filmmaking force. And with the release of a remastered 4K UHD version of Boogie Nights on Monday, December 15, it's the perfect time for the Empire Podcast team — Chris Hewitt, He…
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There's Magic In The Air (ft. guests Shih-Ching Tsou & Sean Baker; Daryl McCormack & Cailee Spaeny; James L. Brooks)
1:56:11
1:56:11
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1:56:11The penultimate regular Empire Podcast of the year is here, folks (don't worry, there are specials galore on the way), and it's a belter. Guest-wise, we have more goodies under the tree, as Jamie Graham talks to longtime collaborators Shih-Ching Tsou and Sean Baker (the director of Anora) about Tsou's directorial debut, Left-Handed Girl, which can …
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F1: An Empire Podcast Interview Special ft. Jerry Bruckheimer, Damson Idris & Kerry Condon
1:04:35
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1:04:35"Yer man's in the pits, boss!" Joseph Kosinski's crowd-pleasingly kinetic F1 was one of the success stories of the year at the box office, displaying impressive legs (or wheels) to take the chequered flag with over $600 million in the global bank, making it the biggest hit of Brad Pitt's career. And now that the film is making its debut on Apple TV…
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Live Christmas Spectacular with Nia DaCosta and Jason Isaacs
1:24:18
1:24:18
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1:24:18Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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Engineering B Cells With Immusoft's Sean Ainsworth
53:51
53:51
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53:51We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Sean Ainsworth, CEO and Chairman at Immusoft, talks about transitioning from the research bench to entrepreneurship, his M&A experiences as a biotech founder, and why engineered B cell therapies offer a better, more patient-friendly administrat…
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QT's Making A List, We're Checking It Twice (ft. guests Taron Egerton; George Clooney & Adam Sandler; Jon M. Chu)
1:58:26
1:58:26
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1:58:26This week's episode of the Empire Podcast sees Christmas on our mind as we enter December, and accordingly we deliver a sackful of great guests to you, our loyal and loving listeners. First off, Chris Hewitt goes to Taron Egerton's actual flat (smells divine... and the flat wasn't bad either) to sit down with him for a candid chat about his career,…
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FIVE NIGHTS AT FREDDY’S 2: “I was struggling to stay awake” + Legendary James L Brooks
1:28:55
1:28:55
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1:28:55Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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The Shameless Plug #10: The Odyssey Odyssey
42:36
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42:36The new episode of The Shameless Plug is here, folks, and this month sees Chris Hewitt sit down with freshly-minted award winner, Empire editor Nick de Semlyen, to delve into one of the most special issues of Empire magazine in many a moon: our world exclusive first look at Christopher Nolan's The Odyssey, for which Nick went on something of an ody…
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Building A Cancer Pipeline In A Molecule With Actuate Therapeutics' Dan Schmitt
51:25
51:25
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51:25We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Dan Schmitt, President and CEO at Actuate Therapeutics, talks about building a company around elraglusib, a GSK-3β inhibitor for cancer. Dan describes his fast-fail approach to early product testing and development, using basket trials to evalu…
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There Can Be Only Dozens (ft. guests Simu Liu; Ke Huy Quan; Richard Linklater & Ethan Hawke)
1:51:41
1:51:41
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1:51:41This week's episode of the Empire Podcast sees Chris Hewitt sit down with two actors who star in animated movies (and ask them both about their favourite things to do in London). First, Simu Liu Zooms in to talk about new Netflix family flick, In Your Dreams, plus his own dreams, and the return of Shang-Chi to the MCU. [21:38 - 38:30 approx] Then, …
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Is CHRISTY a knockout? + Noah Baumbach on JAY KELLY
1:25:22
1:25:22
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1:25:22Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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Biotech Collaboration Strategy With IGI's Cyril Konto, M.D.
58:41
58:41
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58:41We love to hear from our listeners. Send us a message. On this week's episode, Cyril Konto, M.D., president, executive director, and CEO at Ichnos Glenmark Innovation (IGI) talks about the promise of multi-specific antibodies, funding the company during the 'biotech winter,' closing a $700 million upfront licensing deal with AbbVie, the impact of C…
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Now & Ben: Benedict Cumberbatch on THE THING WITH FEATHERS
15:56
15:56
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15:56Howdy Take listeners—it's about time for another Now & Ben, don’t you think? This time it’s Benedict Cumberbatch—who chats to our Ben about his new film ‘The Thing With Feathers’, alongside director Dylan Southern. Based on the bestselling Max Porter novel, the movie follows Cumberbatch’s character ‘Dad’ through his grief at the sudden death of his…
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Escape From Malcatraz (ft. guests Benedict Cumberbatch & Dylan Southern; Joel Edgerton & Clint Bentley; Ariana Greenblatt)
1:57:43
1:57:43
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1:57:43This week's episode of the Empire Podcast sees the podteam — Chris Hewitt, Helen O'Hara, and James Dyer — play themselves as they discuss great 'as themselves' performances in the movies. They also run their collective eye over the week's movie news, including heartening Star Trek developments, review Train Dreams, Wicked: For Good, Playdate, and S…
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WICKED: Which Witch Wins - Is the Sequel/Prequel Equal?
1:23:29
1:23:29
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1:23:29Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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Biotech Funding And IPO Temperature Check With Create Medicine's Allan Shaw
57:01
57:01
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57:01We love to hear from our listeners. Send us a message. Allan Shaw, Chief Financial Officer and Chief Business Officer at Create Medicines, is back on the Business of Biotech this week, with a temperature check on biotech funding and the IPO market. We discuss the implications of recent blockbuster acquisitions, strategies for managing the current f…
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All The Information Is On The Task (ft. guests Edgar Wright, Rosamund Pike & Isla Fisher, Michael Shannon)
1:58:03
1:58:03
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1:58:03This week's episode of the Empire Podcast would surely deserve to get a full fat five points from Greg Davies, the Taskmaster himself, as Chris Hewitt, Helen O'Hara, James Dyer, and John Nugent apply themselves wholeheartedly (some more wholeheartedly than others, it must be said) to deciding which Taskmaster contestant has appeared in the best fil…
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Julia Ducournau & Tahar Rahim On Alpha: An Empire Podcast Interview Special
24:35
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24:35Alpha is the third film from the brilliant French filmmaker, Julia Ducournau, following on from her titanic debut, Raw, and her raw follow-up, Titane (which won the Palme D'Or, no less!). A tale of an unusual epidemic and generational trauma, there's much going on above and below the surface, which we get into in this interview special, as Jamie Gr…
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Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fort…
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Jenny Beavan: An Empire Podcast Interview Special
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45:41
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45:41Nicholas Hytner's The Choral, a delightful drama set in 1916 Yorkshire, is in cinemas now, folks. It features costumes designed by the legendary Jenny Beavan, who is one of the best costume designers in the business. Nominated for 12 Oscars, winner of three, Beavan has worked with directors like Robert Altman, James Ivory, and George Miller across …
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Funding Tips And Moving From R&D To Commercial With Madrigal Pharmaceuticals' Mardi Dier
46:11
46:11
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46:11We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Mardi Dier, CFO at Madrigal Pharmaceuticals, talks about building relationships in investment banking and investor relations before moving into business development and becoming a chief financial officer. Mardi describes how drug companies tran…
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Daniel Day-Lewis, Sean Bean, & Ronan Day-Lewis On Anemone: An Empire Podcast Interview Special
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50:02Every year at the London Film Festival, Empire hosts a gala screening for a film that we particularly admire. This year's choice was Ronan Day-Lewis' Anemone, a drama that we called 'sad, absurdist, brooding, tender, and intense', and which marks the return to acting of the great Daniel Day-Lewis, father of Ronan and co-writer of the movie, after e…
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The Sound Of Burning Felt (ft. guests Jennifer Lawrence & Lynne Ramsay; Elle Fanning & Dimitrius Schuster-Koloamatangi; Sean Bean & Daniel Day-Lewis)
1:51:46
1:51:46
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1:51:46Blimey, this week's episode of the Empire Podcast is star-studded, and then some. First, Chris Hewitt chats with Die, My Love star, Jennifer Lawrence, and director Lynne Ramsay, about unpredictability on set and receiving an email from Martin Scorsese; then, he has a crash course in Yautja from Predator: Badlands stars Dimitrius Schuster-Koloamatan…
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Daniel Day-Lewis and Ronan Day-Lewis on ANEMONE
1:26:37
1:26:37
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1:26:37Some exciting news — The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fo…
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The Shameless Plug #9: Stranger Things Has Happened
43:20
43:20
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43:20Another month, another issue of Empire, another episode of The Shameless Plug. This time, Chris Hewitt and Nick de Semlyen sit down to talk about how Stranger Things ended up on the cover of the world's biggest movie magazine, and nearly did so upside down. And they also talk about less strange things, including the stories behind the stories of th…
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Emerging From Stealth With Vima Therapeutics' Bernard Ravina, M.D.
42:48
42:48
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42:48We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, we're speaking with Bernard Ravina, M.D., CEO at Vima Therapeutics, a company that emerged from stealth in May with $60 million Series A financing to develop an oral candidate for dystonia, a movement disorder. Ravina talks about transitioning …
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Now It's Time For Halloween (ft. guests Edward Berger, Yorgos Lanthimos, Mary Elizabeth Winstead & Maika Monroe)
1:56:15
1:56:15
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1:56:15It's Halloween, folks, so this week's episode of the Empire Podcast is extra-spooky, with Chris Hewitt, Helen O'Hara, James Dyer, and Beth Webb get way too invested in a listener question about the horror movie death that they would want for themselves. Just keep repeating: it's only a podcast, it's only a podcast, it's only a podcast. Elsewhere, o…
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Is BUGONIA out of this world? + Ruth Wilson on DOWN CEMETERY ROAD
1:24:35
1:24:35
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1:24:35Some exciting news — The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor’s Roundup newsletter, and access to a new fo…
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Kenny Dalglish & Asif Kapadia on Kenny Dalglish: An Empire Podcast Interview Special
33:11
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33:11If you can hear a high-pitched squealing noise in the background of our latest interview special, that's just Chris Hewitt vibrating with excitement. For this podcast puts him in the room with one of his all-time heroes, Liverpool FC icon Kenny Dalglish, who is the eponymous subject of Asif Kapadia's latest documentary, which is out today (October …
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BoB in South Florida: Rich Daly, Catalyst Pharmaceuticals
31:47
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31:47We love to hear from our listeners. Send us a message. On this week's episode — the last of our four-part series focused on South Florida — we catch up with Rich Daly, CEO at Catalyst Pharmaceuticals, a member of Life Science Leader's editorial advisory board and Miami-based location host for our in-person series. Rich talks about Catalyst's rare d…
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We've Gone And Caught A Sniffle (ft. guests Nia DaCosta, Jeremy Strong, Rebecca Ferguson & Kathryn Bigelow)
1:59:22
1:59:22
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1:59:22This week's Empire Podcast sees Chris Hewitt struggle with the enunciation of one word in particular (you'll have to listen to find out which). Incredibly, it's not 'Howl-o-ween', which is just one of the many things discussed by Chris and his three colleagues of such lethal cunning, Helen O'Hara, James Dyer, and Ben Travis. They get their teeth in…
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Did Mark ‘Louvre’ Josh O’Connor’s timely heist movie THE MASTERMIND? + Does SPRINGSTEEN deliver?
1:28:45
1:28:45
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1:28:45This Week on the Show: Josh O’Connor, Kelly Reichardt & the Art of the Heist Fresh off the headlines of a real-life Louvre robbery, indie auteur Kelly Reichardt and breakout star Josh O’Connor join Simon to talk about their buzzy new film, The Mastermind—a stylish 70s-set art-heist drama that’s suddenly feeling very timely. O’Connor plays JB, a sla…
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BoB In South Florida: Anthony Japour, M.D., iTolerance
33:34
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33:34We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech -- part three in a four part series recorded in-person at Catalyst Pharmaceuticals' Miami headquarters -- Anthony Japour, M.D., CEO at iTolerance, talks about his work as a physician treating infectious diseases, his CEO role in diagnostics at t…
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Diane, Drew And The Greatest Poster Ever (ft. guests Rebecca Miller, Channing Tatum & Kirsten Dunst, Mason Thames & Madeleine McGraw)
1:59:53
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1:59:53This week's Empire Podcast sees Chris Hewitt, Helen O'Hara and James Dyer pay tribute to two cinematic greats who left us this week: the legendary Oscar-winning actress, Diane Keaton, and Drew Struzan, the artist who defined posters, and people's walls, for decades. Struzan's work inspires this week's question, which asks our trio to identify the g…
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Has FRANKENSTEIN got Mark (re)animated? + Russell Tovey
1:24:14
1:24:14
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1:24:14Vanguardistas have more fun—so if you don’t already subscribe to the podcast, join the Vanguard today via Apple Podcasts or extratakes.com for non-fruit-related devices. In return you’ll get a whole extra Take 2 alongside Take 1 every week, with bonus reviews, more viewing recommendations from the Good Doctors and whole bonus episodes just for you.…
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BoB In South Florida: Daniel Teper, NAYA Therapeutics
33:08
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33:08We love to hear from our listeners. Send us a message. In this week's episode of the Business of Biotech -- part two in a four-part series recorded in-person at Catalyst Pharmaceuticals' Miami headquarters -- we're speaking with Daniel Teper, an entrepreneur and most recently, founder and CEO at NAYA Therapeutics. Based in South Florida, NAYA is de…
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Wish You Well (ft. guests Greta Lee & Jodie Turner-Smith; Robert Aramayo; Gillian Anderson)
1:45:37
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1:45:37This week's episode of the Empire Podcast sees Alex Godfrey display his versatility as an interviewer, going from utter chaos with Tron Ares stars Greta Lee & Jodie Turner-Smith [22:46 - 34:31 approx] and Gillian Anderson [1:33:01 - 1:43:53 approx] to a heartfelt and passionate chat with Robert Aramayo, star of this week's excellent drama, I Swear,…
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TRON: ARES: “It was like my brain was atrophying” + Kathryn Bigelow & Rebecca Ferguson
1:15:46
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1:15:46Vanguardistas have more fun—so if you don’t already subscribe to the podcast, join the Vanguard today via Apple Podcasts or extratakes.com for non-fruit-related devices. In return you’ll get a whole extra Take 2 alongside Take 1 every week, with bonus reviews, more viewing recommendations from the Good Doctors and whole bonus episodes just for you.…
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