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ALP Insights

ALP Insights

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ASSESSMENT FOR LEARNING PROJECT We're fundamentally rethinking assessment. Through a growing community of practice and a grant program funding bold ideas, we’re inviting the field to #rethinkassessment too. Supported by a national group of partner organizations, the Assessment for Learning Project is a multi-year grant program and field-building initiative inviting educators to fundamentally rethink the roles that assessment should play to advance student learning and to improve our K-12 edu ...
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Building Blocks

SS&C ALPS Advisors

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The Building Blocks podcast features financial services thought leaders sharing investment perspectives, market trends and economic insights. SS&C ALPS Advisors is an open architecture boutique investment manager offering portfolio building blocks, active insight, and an unwavering drive to guide clients to investment outcomes across sustainable income, thematic and alternative growth strategies. Please follow, share and subscribe.
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Weekly updates on new data and best practices in patient care for a variety of infectious diseases including COVID-19, HIV, and viral hepatitis, from Clinical Care Options. Gain practical strategies and earn CME/CE credit for selected episodes.
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In this episode, Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH​, discusses the most recent developments in primary biliary cholangitis (PBC) treatment, including cutting-edge data on new and emerging agents and how these updates may be integrated into your practice. Topics include: Steatotic liver disease and PBC Vibration-controlled transient elas…
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Listen as expert faculty answer your most pressing questions on optimizing immunization in clinical practice. Topics covered include: Practical methods for improving confidence in vaccines How to educate patients on vaccine development and safety monitoring Effective strategies to tailor recommendations, such as motivational interviewing Ways to na…
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In this episode, Dr Gideon Hirschfield meets with patient advocate Jess Schnur to discuss challenges related to the diagnosis and management of primary biliary cholangitis (PBC) to provide actionable strategies for healthcare professionals to incorporate into patient care, including: Disease concerns and frequently asked questions from a patient pe…
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In this podcast, Sonal Kumar, MD, MPH, meets with patient advocate Maria Morais to discuss actionable steps that healthcare providers can incorporate into the care of people with primary biliary cholangitis (PBC). Listen as they discuss: The chronic nature of PBC Going beyond biochemical markers to assess and address symptoms such as fatigue and pr…
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In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau, use an illustrative patient case to explore the roles of ALP and other biochemical markers in PBC management, and explain what to expect from treatment. Topics covered include: How baseline ALP can affect ALP normalization after second-line treatment with elafibranor and seladelpa…
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In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau discuss an illustrative patient case to demonstrate how they individualize primary biliary cholangitis (PBC) therapy for patients ​with cirrhosis. Topics covered include: AASLD guideline recommendations for second-line therapy for PBC Considerations when using newer agents for seco…
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In this podcast, Brett M. Elicker, MD, and David E. Griffith, MD, ATSF, FACCP, FRSM, discuss the pathophysiology of non–cystic fibrosis bronchiectasis (NCFBE), the patient burden, and best practices with diagnosing NCFBE, including: The vicious vortex of NCFBE (ie, airway dysfunction, inflammation, infection) Cough as the most significant symptom a…
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In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss how they assess the symptoms of primary biliary cholangitis (PBC) and explore how new therapeutic agents may help alleviate symptom burden. Topics include: Strategies and tools for assessing pruritus Nonpharmacologic and pharmacologic management of pruritus Secon…
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How do you decide when to move from first-line to second-line treatment for primary biliary cholangitis (PBC)? In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss this question and more, including: How and when to measure treatment response Evidence-based goals of therapy Considerations for second-line treatment N…
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Respiratory Syncytial Virus (RSV) significantly impacts adults, especially those over age 60 and those with chronic conditions. In this podcast, nurse practitioners Drs. Carrico and Stevenson discuss the underestimated burden of RSV. The podcast also explores practical strategies for increasing vaccine uptake that you can apply to your practice sta…
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Listen in as Carolyn Bridges, MD, FACP, and Laura P. Hurley, MD, MPH, discuss barriers to respiratory syncytial virus (RSV) vaccination for adults, including insurance coverage and vaccine hesitancy, and explore effective, practical strategies for overcoming these barriers. Topics covered include: Helping patients understand why they need an RSV va…
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Listen in as Carolyn Bridges, MD, FACP, reviews the estimated burden of respiratory syncytial virus (RSV) disease in older adults and discusses the latest updates on RSV vaccination recommendations and safety data. Topics covered include: Rates of RSV hospitalizations and emergency department visits RSV vaccine development FDA-approved RSV vaccines…
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In this episode, Jewel Mullen, MD, MPH, MPA, and Dallas Nelson, MD, CMD, FACP discuss overcoming barriers to RSV vaccine uptake in post-acute and long-term care facilities, including: How to incorporate the latest RSV vaccination recommendations into clinical practice Practical strategies for navigating insurance Effective and empathetic methods of…
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In this episode, Chloe Orkin, MBChB, FRCP, MD, and Jean-Michel Molina, MD, PhD, discuss highlights from CCO’s independent conference coverage of CROI 2025, including: Advances in HIV treatment based on results from CARES Potential HIV therapies in the pipeline, such as doravirine/islatravir Effects of broadly neutralizing antibodies on HIV treatmen…
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Listen in as Cristina Mussini, MD; Martin Witzenrath, MD, FERS; and Michele Bartoletti, MD, PhD, discuss treatment strategies for people who are immunocompromised with COVID-19 in the hospital setting, including: Antiviral therapy with remdesivir Dexamethasone for patients with hematologic malignancies Considerations regarding other immunomodulator…
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In this episode, Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss treatment strategies for people who have severe COVID-19, including: Antiviral therapy with remdesivir Dexamethasone and other systemic corticosteroids Immunomodulators, such as JAK inhibitors or IL-6 inhibitors Overviews of clinical tria…
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In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss practical strategies to overcome barriers to hepatitis B virus (HBV) care, including: Overcoming health insurance navigation Improving access to HBV care in immigrant communities Dispelling HBV myths and s…
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In this episode, Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss: Workup of COVID-19 in the emergency department Methods of COVID-19 risk stratification Treatment recommendations for people with severe COVID-19, including how to effectively use antiviral therapy, dexamethasone, and other immunomodulato…
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In this episode, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss the management of mild to moderate COVID-19 in patients who are immunocompromised, including: Initial workup, which may include laboratory tests and/or imaging Latest data on the use of remdesivir or nirmatrelvir plus ritonavir for mild to moderate COVID-19, incl…
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In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss best practices in hepatitis B virus (HBV) care, including: 2023 CDC HBV screening recommendations Summary of guideline recommendations for hepatitis delta virus (HDV) screening Use of HDV reflex testing to…
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In this episode, Cristina Mussini, MD, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss: Current SARS-CoV-2 trends in the EU Risk factors for severe COVID-19 outcomes, including the spectrum of risk based on immune system status Factors that may affect vaccine efficacy in chronic lymphocytic leukemia and other lymphoid malignan…
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In this episode, Tzu-Hao (Howard) Lee, MD; Tatyana Kushner, MD, MSCE; and patient advocate Andrew Reynolds discuss hepatitis C virus (HCV) care in men who have sex with men and pregnant people, including: HCV disease burden in the United States Screening recommendations Strategies to overcome barriers to HCV screening Treatment recommendations, inc…
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In this episode, Sonal Kumar, MD, MPH, discusses key findings from primary biliary cholangitis (PBC) studies presented at AASLD 2024, including: ELATIVE, a phase III trial of elafibranor for PBC RESPONSE, a phase III trial of seladelpar for PBC ASSURE, another phase III trial of seladelpar for PBC Presenter: Sonal Kumar, MD, MPH Director, Clinical …
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Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss current trends in and risk factors for progression to severe COVID-19, including for those for whom COVID-19 is not their primary concern when presenting to the emergency department (ED). Key topics of discussion include: How to complete a co…
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In this episode, Stacey B. Trooskin, MD, PhD, MPH, Mark S. Sulkowski, MD, FIDSA, FAASLD, and Ronni Marks discuss hepatitis C virus (HCV) screening and treatment, focusing on people who use drugs, and highlight the following topics: Screening recommendations Strategies to improve HCV screening HCV testing Treatment goals Strategies to improve HCV tr…
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Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss best practices in treating patients hospitalized with mild to moderate COVID-19, including: Current guidelines from the Infectious Diseases Society of America and National Institutes of Health How to optimize therapy selection based on patien…
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Clinical gaps in the treatment of pruritus in primary biliary cholangitis (PBC) remain. In this episode, taken from a recent symposium, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss emerging therapies currently in clinical trials for the management of this disease that can dramatically affect patien…
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Although there is currently no FDA-approved treatment for pruritus in primary biliary cholangitis (PBC), symptoms can be mitigated with nonpharmacologic or pharmacologic agents. In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss the clinical management of pruritus in PBC, including: Prur…
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In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with primary biliary cholangitis (PBC), discuss the burden of pruritus in PBC and the impact it has on quality of life, including both physical and mental health, from a patient’s perspective. Presenters: Marlyn J. Mayo, MD Professor of Internal Medicine …
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In this episode, Jean-Michel Molina, MD, PhD, and Joseph J. Eron, Jr., MD, discuss results from key clinical trials on HIV prevention and treatment as well as sexually transmitted infection (STI) prevention presented at IDWeek and Glasgow 2024, including: PURPOSE 1 and 2 comparing lenacapavir injection vs oral TDF/FTC TRIO Health Cohort and OPERA e…
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In this episode, Christopher L. Bowlus, MD, discusses recent advances in the management of primary biliary cholangitis (PBC), including: Treatment goals Use of PPAR agonists for the treatment of PBC Clinical trial results for elafibranor (ELATIVE), seladelpar (RESPONSE), and bezafibrate (BEZURSO) Presenter: Christopher L. Bowlus, MD Lena Valente Pr…
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In this episode, a transfemme nonbinary individual living with HIV shares her experience navigating the healthcare system, alongside her infectious disease physician, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS. Hear them discuss key considerations when caring for gender-diverse individuals, including: Understanding how people are more than j…
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In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including: Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudy Implementing in…
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Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to achieve health equity in HPV vaccination, including: Trends among males vs females Messaging considerations for those from diverse populations (eg, LGTBQ+ and rural communities) How healthcare professionals can address barriers to care Then, hear answers fr…
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Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to improve your messaging techniques with the HPV vaccine, including: Persisting in vaccine recommendation after initial refusal Educating patients and their families together Ensuring staff are trained to correctly answer questions Knowing when interested pat…
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Listen in as Sharon G. Humiston, MD, MPH, discusses current trends in HPV, including: Incidence and prevalence trends in the US Sex-related features of HPV-attributable cancers How HPV vaccination uptake can prevent certain types of cancer Current guidelines and recommendations for HPV vaccination Presenter: Sharon G. Humiston, MD, MPH Director for…
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In this episode, Kathleen Page, MD, and Glenn J. Treisman, MD, PhD, discuss the interplay between addiction and HIV. Learn as they share their approaches to reframing the conversation about addiction and overcoming barriers to effective addiction care for people living with HIV. Presenters: Kathleen Page, MD Professor Infectious Diseases Johns Hopk…
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In this episode, Alexander Wong, MD, FRCPC, discusses how to optimize treatment and engagement in care for individuals with HIV and substance use disorder, including: Barriers to care for persons with substance use disorder Colocating HIV and other services (eg, addiction care medicine, social services) Leveraging a multidisciplinary approach to ca…
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In this episode, Jennifer Cocohoba, PharmD, AAHIVP, and David Koren, PharmD, MPH, AAHIVP, FIDSA, cover the most impactful LA ART and LA PrEP clinical studies presented at AIDS 2024, including: The PURPOSE 1 study of twice-yearly lenacapavir injections vs daily oral tenofovir as PrEP in cisgender women An open-label extension of HPTN 084 evaluating …
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In this episode, Tristan J. Barber, MA, MD, FRCP, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating PTSD in people with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, sharing their own experiences and approaches to thinking about PTSD, structuri…
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In this episode, Colleen F. Kelley, MD, MPH, and Jemma Samitpol discuss key considerations to improve the patient experience among transgender persons with HIV, including: Unique circumstances faced by transgender people trying to access HIV care (eg, stigma, discrimination) Best practices to improve access and linkage to HIV care Ways to integrate…
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In this episode featuring faculty from the United States and Europe, Aadia I. Rana, MD, and Laurence Slama, MD, PhD, discuss the subtleties of deciding among HIV treatment options in people with adherence challenges. Listen as they debate the potential risks and benefits of long-acting ART in this population, considerations for people with viremia …
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In this episode, Gregory Huhn, MD, MPHTM, presents a case study of a person with a long HIV treatment history, exploring when and how to consider agents with novel mechanisms of action. Listen as he discusses: The importance of engaging with patients to understand their perspectives and improve their satisfaction with their HIV care Options in peop…
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In this episode, Yvonne Gilleece, MB BCh, BAO, FRCP, uses a case study to illustrate why giving people space and time to engage in HIV care on their terms is key to overcoming potential shame and stigma. She discusses how people can be very vulnerable when engaging in HIV care, and trauma-informed care can help address these vulnerabilities in a sa…
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In this episode, George Lau, MD, FRCP (Edin, Lond), FHKAM (Med), FHKCP, FAASLD, MBBS (HKU), and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including: Consequences to poor adherence to antiviral therapy Strategies to promote medication adherence (eg, patient education, setting up routines) The ro…
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In this episode, Gregory Huhn, MD, presents a case study exploring how to optimize oral ART for a person with a long history of different ART regimens. Listen as he discusses: Reasons to consider regimen optimization in the setting of viral suppression Evidence for INSTIs in the setting of resistance Data on when 2-drug regimens and long-acting reg…
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In this episode, Lucas Hill, PharmD, AAHIVP, BCACP, and Bernadette Jakeman, PharmD, PhC, BCPS, AAHIVP,discuss what pharmacists need to know to provide high-quality HIV care beyond viral suppression, including treatment strategies and tips for addressing and improving patients’ quality of life. Listen as they discuss: Reasons to consider regimen opt…
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In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss strategies for optimizing PBC pruritus care in the clinic setting. Listen to their conversation on how important it is to ask patients about their pruritus, validate their symptoms and feelings, and offer treatment options framed with realis…
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In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss the patient experience with cholestatic pruritus in PBC. Listen to their conversation on how people describe the experience of cholestatic pruritus, the extent to which pruritus negatively affects quality of life, and the importance of educa…
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