Best Aaron Sharma Podcasts (2025)

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What Is Uric Acid and How Does It Predict Your Longevity : 1321 1:09:44

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2d ago1:09:44

1:09:44

Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer’s, and even accelerated aging—and how you can hack it to unlo…

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Hacking Dopamine Naturally: Pain, Focus, and Performance : 1320 1:15:10

4d ago1:15:10

1:15:10

Your dopamine system is being hijacked every day, and the way to reclaim it might surprise you. This episode reveals how pain, pleasure, and addiction are wired in your brain, and how to use that knowledge for real brain optimization, resilience, and longevity. You’ll discover why your dopamine levels control motivation, focus, mood, and even cravi…

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You Have A 25% Chance to Lose All Your Memory (Longevity Secrets) : 1319 1:46:41

5d ago1:46:41

1:46:41

Alzheimer’s is not inevitable—and it may even be optional. In this groundbreaking episode, you’ll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBP…

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The Hormone War Dividing Female and Male Longevity : 1318 53:48

9d ago53:48

53:48

Your hormones may be waging a hidden war that determines how long you live and how well you perform. This episode reveals how male and female biology diverge—and what those differences mean for your longevity, metabolism, and brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Revi…

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The 10-Second At-Home Walk Test for Longevity (Easy Biohack) : 1317 1:07:06

11d ago1:07:06

1:07:06

Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You’ll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pe…

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PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316 1:08:04

13d ago1:08:04

1:08:04

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade …

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Still Fasting in 2025? Here’s How to Make It Work Better : 1315 59:50

17d ago59:50

59:50

How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mito…

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How to Make Life-Changing Decisions Without Fear – Joe Hudson : 1314 52:09

17d ago52:09

52:09

How do you make tough decisions? How do you make them without fear or lying? This episode shows you how unresolved emotions disrupt decision-making, relationships, and functioning in peak brain performance. You’ll learn tips to rewire your nervous system for decision making, optimizing emotional intelligence, and regulating your body for high-level…

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The New Poisons Lurking Around You – Save Your Longevity : 1313 58:58

20d ago58:58

58:58

Toxins you cannot see are damaging your health, wrecking your metabolism, and quietly accelerating aging. This episode reveals how to detect the new poisons lurking in your home, how they sabotage mitochondria and brain optimization, and the biohacking fixes that restore longevity, energy, and human performance. You’ll learn actionable strategies y…

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Jim Kwik: What I Take to Biohack Brain Speed and Focus : 1312 59:39

24d ago59:39

59:39

Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization protocols Jim Kwik uses daily, plus the biohacking routines that rebuilt his cognition after traumatic brain injury. Watch this episode on YouTube for the …

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Why I Inject a “Female Hormone” 3x a Week (Nootropic Hacking) : 1311 1:38:53

25d ago1:38:53

1:38:53

What if the most powerful upgrades for brain energy, metabolism, and drive aren’t in mainstream medicine, but in rare peptides and misunderstood hormones? In this episode, you’ll discover the cutting-edge compounds, nootropics, and hormonal strategies that elite biohackers are using right now to optimize every part of their biology. Watch this epis…

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Top 5 Dopamine Boosting Biohacks for Superhuman Energy : 1310 1:04:20

27d ago1:04:20

1:04:20

Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, and biohacking protocols that top performers are using to supercharge human performance, brain optimization, and long-term resilience. Watch this epis…

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Protein vs. Plants: The 50g-a-Meal Biohacking Rule : 1309 47:04

1M ago47:04

47:04

Getting 50 grams of protein per meal may be the single most underrated biohacking protein strategy for muscle growth, metabolism, and longevity. In this episode, you’ll discover why animal protein vs vegan is not a fair match biologically, how hitting the leucine threshold activates mTOR for longevity, and why muscle is the most overlooked organ of…

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The Air Force Uses This Mind-Bending Sound Biohack — Try It Yourself! : 1308 54:05

1M ago54:05

54:05

This episode reveals how military-grade sound frequencies can rapidly shift your mental state, enhance neuroplasticity, and accelerate brain optimization. You’ll learn how to hack your nervous system using real-time biometric data, how frequency compositions are changing functional medicine, and why sound is emerging as one of the most powerful too…

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How To change ANY Habit In 63 Seconds (No Willpower Needed) : 1307 59:15

1M ago59:15

59:15

You’ve been lied to about how long it takes to change a habit. This episode reveals a powerful, science-backed method to rewire your brain in just 63 seconds—without relying on willpower. You’ll discover how to use the 63-second window to interrupt destructive thought loops and how true habit change requires 63-day habit formation, not the populari…

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Who Should Take Herbal Ecstasy Supplements? (The Billion-Dollar Backstory) : 1306 59:12

1M ago59:12

59:12

What is Herbal Ecstasy—and why does it matter? This might be one of the most insane episodes we’ve ever recorded, and we had to bring it back because the story is too wild, too relevant, and too packed with real lessons in biohacking, brain optimization, and supplement hacking to miss. Host Dave Asprey sits down with Shaahin Cheyene, the renegade t…

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Boost Brain Power by 25% WITHOUT a Pill (Brain Optimization Secrets) : 1305 1:10:55

1M ago1:10:55

1:10:55

You’re leaving brainpower on the table, and this episode shows you how to reclaim it. Learn how to boost cognitive performance by 25% without relying on pills, stimulants, or gimmicks. Host Dave Asprey sits down with global finance expert and cross-cultural thinker Richard Conrad to explore how your cultural programming shapes your biology, metabol…

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The Biohacking Tool That Will Change the World (Mitochondrial Transfusions) : 1304 54:24

1M ago54:24

54:24

This may be the most cutting-edge life extension technology you’ll hear about for decades. You’ll discover how mitochondrial transfusion, rejuvenation, and repair could reverse biological aging, supercharge your metabolism, and radically extend healthspan—all by upgrading the cellular energy systems that power every function in your body. Watch thi…

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The Fastest-Acting Nootropic I’ve Ever Used : 1303 46:00

1M ago46:00

46:00

What if one spray could upgrade your brain, protect your mitochondria, and outperform IV therapy and liposomal supplements? In this episode, you’ll discover the breakthrough science behind topical glutathione delivery that uses your skin’s water channels to raise intracellular glutathione levels in just 60 seconds. Learn how this powerful antioxida…

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Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway) : 1302 53:57

2M ago53:57

53:57

If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal why this overlooked molecule controls your blood flow, mitochondrial energy, neuroplasticity, insulin response, and even your libido. You’ll learn how n…

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Easy Oxygen Hacking for Mitochondria (The 15-Minute Upgrade) : 1301 49:51

2M ago49:51

49:51

Supercharge your mitochondria, slash inflammation, and boost energy with one of the most overlooked hacks in human performance. This episode reveals how just 15 minutes of oxygen-based exercise can radically improve metabolism, brain optimization, and even reverse chronic conditions, without expensive gear or endless protocols. Watch this episode o…

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Facelifts, Breast Implants, and the REAL Fix for Wrinkles : 1300 57:25

2M ago57:25

57:25

Wrinkles are just the surface. This episode reveals what’s really happening beneath your skin and how to reverse it using stem cells, regenerative medicine, and the most advanced techniques in plastic surgery and aging. You’ll learn how to improve facial skin tightening, reduce inflammation, and trigger deep skin rejuvenation with stem cells, red l…

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Superintelligence, Transhumanism & Biohacking in 2027 : 1299 1:17:52

2M ago1:17:52

1:17:52

Superintelligence is coming faster than anyone predicted. In this episode, you’ll learn how to upgrade your biology, brain, and consciousness before AI and transhumanism reshape the future of health. Host Dave Asprey sits down with Soren Gordhamer, founder of Wisdom 2.0, to explore what superintelligence in 2027 means for your mind, body, and soul.…

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#359 - Inside Bullish: Lessons from Backing Major DTC Winners (Peloton, Harry’s, Warby Parker) 47:57

2M ago47:57

47:57

Brent Vartan is Managing Partner and Co-Founder at Bullish, a unique hybrid combining a branding agency and a consumer-focused venture fund. With decades of experience in brand strategy, Brent and his team have been early investors and builders behind some of the most iconic DTC and consumer brands of the past decade, including Peloton, Warby Parke…

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Why I Add Creatine to My Coffee Every Morning (And You Should Too) : 1298 30:41

2M ago30:41

30:41

Creatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episode reveals why creatine is a non-negotiable supplement for anyone serious about biohacking, longevity, and cognitive upgrades. Watch this episode on Yo…

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Death, Legacy & the Philosophy of Longevity — with Stephen Cave : 1297 57:09

2M ago57:09

57:09

What if death isn’t inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You’ll learn why some of today’s top thinkers are treating longevity as both a science and a spiritual movement, and how this shift affects your brain, your mitochondri…

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Fix What’s Making You Feel Old—From Joints to Mitochondria | Dr. Greg Kelly : 1296 45:39

2M ago45:39

45:39

You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden causes of early aging like mitochondrial dysfunction, leaky gut, and chronic inflammation. Watch this episode on YouTube for the full video experience:…

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The Ultimate Guide to a Metabolism That Burns Fat Again — with Ben Azadi : 1295 1:06:15

2M ago1:06:15

1:06:15

93% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap to reboot your metabolism, escape the sugar-burning trap, and reignite your fat-burning engine for good. Watch this episode on YouTube for the full vi…

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Why Your Workouts Aren’t Giving You a Summer Body — with Nick Bare : 1294 49:23

2M ago49:23

49:23

You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do instead. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with performance-dr…

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#358 - The AI Ad Strategy Every DTC Brand Needs in 2025 feat. Bestever CEO Apoorva Govind 52:05

2M ago52:05

52:05

Apoorva Govind is the founder and CEO of Bestever, a platform focused on helping brands and marketers generate ad creatives powered by real performance data and advanced AI models. With a background spanning technical roles at Apple, Uber, and Nvidia, Apoorva brings unique insights into the intersection of technology and growth marketing. In this D…

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The Plants That Reverse Aging And Block Daily Toxins — with Darin Olien : 1293 1:05:01

2M ago1:05:01

1:05:01

Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You’ll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxins disrupting your hormones, brain, mitochondria, and overall health. This is a masterclass in biohacking from two experts who’ve spent decades resear…

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The Anti-Aging Skincare Trends That Are DAMAGING Your Skin | Amitay Eshel : 1292 1:08:34

3M ago1:08:34

1:08:34

Your anti-aging skincare routine might be secretly aging you faster. In this episode, you’ll uncover how trending skincare products including vitamin C serums, harsh exfoliants, and blue light therapies can damage your skin’s mitochondria, accelerate senescence, and trigger systemic inflammation. You’ll learn how to reverse this damage, support cel…

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Why Most Supplements Are a WASTE of Money (And What Actually Works) : 1291 43:21

3M ago43:21

43:21

Most supplements don’t work, and this episode reveals why. You’ll learn how to stop wasting money on “expensive pee,” how to spot marketing lies on labels, and which ingredients actually move the needle for energy, focus, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asp…

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Can Injectable MDMA Become the Next Biohack in 2026? RFK Jr. vs FDA – Rick Doblin : 1290 53:28

3M ago53:28

53:28

Psychedelic therapy is on the verge of reshaping mental health, trauma healing, and human consciousness. This episode reveals what’s really happening behind the scenes at the FDA, inside pharmaceutical companies, and within the global movement to legalize MDMA-assisted therapy. Watch this episode on YouTube for the full video experience: https://ww…

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Should You Eat Dirt? The “Healthy” Foods Destroying Your Gut – Dr. Josh Axe : 1289 1:05:58

3M ago1:05:58

1:05:58

You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boosting mitochondria, and rebuilding your biology from t…

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How 5G Affects Brainwaves (and the New Science to Fix It) : 1288 52:54

3M ago52:54

52:54

Your brain is under constant assault from devices you use every day. This episode reveals the hidden effects of 5G on brain function, cognitive performance, and nervous system stress, along with the science-backed method that neutralizes the damage. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR …

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Mark Sisson: The Japanese Walking Hack That Outperforms 10,000 Steps A Day : 1287 1:22:37

3M ago1:22:37

1:22:37

Most people think 10,000 steps a day is the gold standard for health, but it’s outdated, inefficient, and often damaging. In this episode, you’ll discover a smarter, faster way to walk for longevity, fat burning, and total body resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave …

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#357 - Product First, Creator Second: How 1Up Candy Hit $10M in 10 Months feat. VOID CEO Chris Koch 43:45

3M ago43:45

43:45

Chris Koch is the founder and CEO of VO/D, a venture studio that partners with massive talent celebrities to build enduring CPG brands across DTC, e-commerce, and retail. With a background in sports, investment banking, and talent management, Chris brings deep experience in identifying consumer needs, pairing them with the right creators, and execu…

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60 Days Alone in Antarctica: Amputation, Frostbite, and Lessons from Extreme Suffering | Akshay Nanavati : 1286 1:15:05

3M ago1:15:05

1:15:05

This episode dives into the brutal, mind-altering experience of spending 60 days alone in Antarctica, and how extreme suffering became a catalyst for spiritual awakening, peak performance, and deep inner peace. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with elite a…

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10-Second Breath Hack to Reset Your Body & Mind | Aaron Alexander : 1285 58:34

3M ago58:34

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This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Aaron Alexander, a world-renowned h…

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Ayurveda Meets Biohacking: 5000-Year-Old Medicine Secrets for Modern Stress | Mona Sharma : 1284 59:11

3M ago59:11

59:11

This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mona Sharma, a renowned Ayu…

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The Biohacker’s Guide to CIA Mind Control & Brainwashing : 1283 1:03:44

3M ago1:03:44

1:03:44

You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours. Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Sc…

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Listener Favorites: Paul Millerd | The Pathless vs Default Path 1:05:17

3M ago1:05:17

1:05:17

Join us for a compelling conversation with Paul Millerd, author of The Pathless Path. In this episode, Paul shares his insights on finding yourself in the wrong life and the real work of figuring out how to live. Discover his journey through experiments, travels, and lessons learned, as he pieces together a set of principles to guide him from unful…

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Military Tech Goes Public: Think 30% Faster with This Brain Hack | Geoffrey Woo : 1282 1:26:32

4M ago1:26:32

1:26:32

Your brain runs slow when it’s running on the wrong fuel. In this episode of The Human Upgrade, Dave Asprey sits down with Geoffrey Woo, Stanford-trained computer scientist and founder of Ketone-IQ, to reveal the high-performance brain fuel once reserved for Special Forces and elite athletes. Discover how ketones helped operators in combat zones sh…

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The Anti-Aging Chamber That Rewinds Your Biological Clock|Dr. Jason Sonners : 1281 49:05

4M ago49:05

49:05

Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You’ll learn ho…

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The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon : 1280 1:11:03

4M ago1:11:03

1:11:03

Your brain has a gear you’ve never touched. Psychedelics can shift you into it. In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science. You will le…

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#356 - 0 to $50M in 24 Months: The Explosive Growth Story of BRĒZ feat. CEO Aaron Nosbisch 48:16

4M ago48:16

48:16

Aaron Nosbisch is the founder and CEO of BRĒZ, a cannabis social tonic beverage designed as an alcohol alternative that offers a euphoric, feel-good effect without the downsides of alcohol. He built his expertise in e-commerce from an early age, launching multiple internet brands and scaling previous ventures like MONQ (portable aromatherapy diffus…

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Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah : 1279 1:05:01

4M ago1:05:01

1:05:01

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it. In this episode of The Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixe…

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The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD : 1278 1:12:45

4M ago1:12:45

1:12:45

Your environment is rewiring your hormones, fertility, and long-term health without your consent. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking…

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Biohacking Your Heart Health: The Life-Saving Molecule You NEED to Know | Dr. Anurag Singh : 1277 1:04:18

4M ago1:04:18

1:04:18

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why po…