A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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The (Epic) Arc of a Patient Journey with Seth Hain
26:00
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26:00Seth Hain, SVP of R&D at Epic, joins a16z Bio + Health general partner Julie Yoo to explore technology in healthcare. Reflecting on over two decades of industry shifts, Seth shares how Epic has transitioned from enabling integrated systems within health systems to driving cross-ecosystem collaboration and rapid innovations like generative AI. They …
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Building for the Healthcare Consumer with Elliot Cohen
26:01
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26:01Elliot Cohen, cofounder of PillPack, joins Julie Yoo, a16z Bio + Health general partner. Together, they discuss Elliot's experience designing and building a consumer-first pharmacy alongside TJ Parker. Elliot's journey with PillPack began when he noticed his father struggling with a mail-order pharmacy that couldn’t get the simplest thing right: th…
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Scaling Mental Health Access through AI with Neil Parikh and Daniel Cahn
25:40
25:40
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25:40In this episode, Slingshot AI cofounders Daniel Cahn and Neil Parikh join a16z Bio + Health general partner Julie Yoo to explore how their mission to transform mental health care with AI took shape. Drawing from their unique journeys—Daniel as the son of a psychologist and Neil as a former medical student-turned-entrepreneur—they discuss the challe…
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An Ironman Suit for Doctors with Muthu Alagappan
23:33
23:33
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23:33Dr. Muthu Alagappan, MD, founder and CEO of Counsel Health, joins Julie Yoo, a16z Bio + Health general partner, to dive deep into the company's vision for revolutionizing healthcare through AI-powered asynchronous care. Together, they unpack how Counsel enables on-demand access to real doctors for instant medical guidance, lessening patient relianc…
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Voice AI: Solving Healthcare's Workforce Challenges with Ankit Jain
30:03
30:03
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30:03Ankit Jain, CEO and cofounder of Infinitus Systems, Inc, joins Julie Yoo, a16z Bio + Health general partner, to discuss Infinitus's work in solving one of healthcare's most pressing challenges: workforce shortages. Leveraging LLMs and AI voice agents, Infinitus automates repetitive tasks, such as benefits verification and prior authorization, freei…
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Transforming Clinical Trials with Alexander Saint-Amand
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24:53Alexander Saint-Amand, cofounder and CEO of Topography, reflects on his journey from leading Gerson Lehrman Group (GLG), a pioneer in expert networks, to tackling systemic barriers in clinical trials at his current company, Topography. Inspired by personal experiences, Alexander’s mission centers on democratizing access to clinical research by tran…
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Scaling Medicaid Innovation with Afia Asamoah, Rajaie Batniji, and Sanjay Basu
33:45
33:45
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33:45Rajaie Batniji, MD, PhD, Afia Asamoah, JD, and Sanjay Basu, MD, PhD, cofounders of Waymark, join Vineeta Agarwala, MD, PhD, a16z Bio + Health general partner, to discuss their transformative approach to Medicaid care delivery. This episode dives into their rising risk signal prediction framework, where cutting-edge machine learning predicts patient…
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Super Staffing in Healthcare with Munjal Shah
24:36
24:36
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24:36Hippocratic AI cofounder and CEO Munjal Shah joins a16z Bio + Health general partner Julie Yoo to explore the incredible potential of generative AI in transforming healthcare delivery. Together, they discuss the emerging "voice renaissance" in healthcare, the nuances of designing safe and empathetic AI interactions, and how Hippocratic AI is addres…
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Lessons from Healthcare Infrastructure Pioneers with Jeff Margolis
23:26
23:26
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23:26Jeff Margolis, founder of TriZetto, joins Julie Yoo, a16z Bio + Health general partner, to share the journey of building an iconic company in healthcare infrastructure. From the early days of managed care to creating a three-pronged platform uniting computing power, software, and data analytics, Jeff reflects on TriZetto’s groundbreaking model that…
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Rare Disease, Big Impact with Matt Wilsey
23:08
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23:08In this episode, Matt Wilsey joins Jorge Conde to share the profound personal story of his daughter Grace's diagnosis with NGLY1 deficiency and how it catalyzed his journey to founding a biotech startup, Grace Science, aimed at developing a cure for his daughter’s condition. Matt emphasizes the importance of strategic partnerships, like his collabo…
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Bioorthogonal Chemistry with Carolyn Bertozzi
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31:02
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31:02Nobel laureate Carolyn Bertozzi joins Jorge Conde to unravel the concept of bioorthogonal chemistry. Carolyn traces her pioneering path from early studies in carbohydrate chemistry to how her lab developed the revolutionary ability to manipulate chemical reactions inside the human body. Together, they highlight the intersection of cutting-edge acad…
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Mastering Data with Sajith Wickramasekara
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26:45
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26:45In this episode, a16z partners Jorge Conde and Jay Rughani sit down with Sajith Wickramasekara, CEO and cofounder of Benchling, to unpack the evolution of Benchling from idea to transformative software platform. Saji discusses his journey from software engineer to building Benchling and digitizing biotech workflows for industry giants like Sanofi. …
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Build Your Own Provider Network with Dan Rosenthal
24:41
24:41
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24:41Join healthcare expert Dan Rosenthal and a16z Bio + Health general partner Julie Yoo in a deep dive into the evolution of provider networks and their strategic importance in the health insurance ecosystem. Dan discusses how networks are built, managed, and optimized for both cost and quality—including the complexities of payor-provider contracts, t…
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The Freedom to Choose Your Own Insurance with Chris Ellis and Adam Stevenson
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27:54Chris Ellis, CEO and Adam Stevenson, president, both cofounders of Thatch, join Julie Yoo and Jay Rughani of a16z Bio + Health. In early 2020, a new policy called ICHRA altered the insurance market, which had remained largely unchanged for decades. As you’ll hear in the episode, it’s been slow to catch on — but the cofounders of Thatch think it’s a…
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From Surgeon to Biotech CEO with Jonathan Lim
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27:36
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27:36Jonathan Lim is the CEO of Erasca, but his career path took him on a fascinating journey from practicing as a surgeon to leading life science companies. In a recent conversation, Lim shared valuable insights about his transition to the biotech world, his leadership experiences, and the lessons he's learned while founding and guiding organizations t…
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In this episode, Vijay Pande and Daisy Wolf of a16z Bio + Health join a16z Podcast host Steph Smith to make a provocative case for why technologists—not just medical professionals—are key to reinventing healthcare. They argue that to transform a sector representing 20% of U.S. GDP, innovation must move beyond curing diseases toward tackling healthc…
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Marta Bralic Kerns, founder and CEO of Pomelo Care, joins Will Shrank, MD, a16z Bio + Health venture partner. Together, they talk about the innovator’s dilemma with building in the Medicaid space, how Pomelo partners with managed care plans, and the opportunity to potentially lower costs through providing additional support to pregnant women. This …
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Nikita Singareddy, cofounder and CEO of Fortuna Health, joins Will Shrank, MD, a16z Bio + Health venture partner. Together, they discuss building a useful and convenient platform for Medicaid enrollees, listening to patient feedback to improve, and the complexities of different states’ Medicaid processes. This is the second episode in our Medicaid …
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Over the next three episodes, we’re going to talk about why Medicaid matters, and the potential for technology to make it easier for enrollees to access and utilize the program. Our first guest is Mark Smith, MD, Clinical Professor of Medicine at UCSF. He was the founding President and former CEO of the California HealthCare Foundation from 1996-20…
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Vijay Pande, PhD, founding partner of a16z Bio + Health, joins Derrick Harris, host of the AI + a16z podcast. Together, they discuss how computer science has subsumed biotech.By a16z
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Good Energy, Better Health with Casey Means
29:07
29:07
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29:07Casey Means, MD, a Stanford-trained physician, cofounder of Levels, and author of the new book Good Energy, joins Vijay Pande, PhD, founding partner of a16z Bio + Health. Together, they discuss the downsides of physician specialization, the rising tide of chronic illness in the U.S., and how tracking biomarkers might allow people to determine the b…
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Adapting Biopharma to AI: A 2024 Update with Greg Meyers
25:55
25:55
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25:55Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb, or BMS, joins Jorge Conde, general partner at a16z. This is a follow-up to their 2023 episode, where they discussed how biopharma can adapt to AI. Now, they revisit the conversation to see what’s changed and what hasn’t. Together, they chat through tech as a competit…
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Harnessing Water Dynamics for Drug Design with Michael Crackower and Jason Burch
37:24
37:24
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37:24Michael Crackower, PhD, Chief Scientific Officer of Ventus Therapeutics, and Jason Burch, PhD, join Vineeta Agarwala, MD, PhD, general partner at a16z Bio + Health. Together, they talk about how Ventus approaches drug discovery and why they believe we’re in the early stages of small molecule innovation. Specifically, we’ll hear about the ReSOLVE pl…
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AI at the Intersection of Bio with Vijay Pande, Surya Ganguli, and Bowen Liu
30:08
30:08
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30:08Bowen Liu, PhD, investing partner, and Surya Ganguli, PhD, venture partner, join Vijay Pande, PhD, general partner of a16z Bio + Health. Together, they detail different methods through which AI could assist drug development, the opportunity for AI to flag new targets and compounds for scientists to investigate, and the science fiction-sounding noti…
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The History and Future of CAR T with Bruce Levine
31:26
31:26
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31:26Bruce Levine, PhD, the Barbara and Edward Netter Professor in Cancer Gene Therapy at the University of Pennsylvania, joins Jorge Conde, general partner, and Ginger Liau, partner at a16z Bio + Health. Bruce talks about how his time working in a lab at the Children’s Hospital of Philadelphia inspired him to work on translational therapies. Together, …
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Implementation, Data, Impact of Healthcare AI with Vijay Pande and Julie Yoo
35:28
35:28
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35:28In this episode, a follow-up to our episode Grand Challenges in Healthcare AI, Julie Yoo and Vijay Pande, a16z general partners, answer audience questions about AI applications in healthcare. Together, they dive into cost and implementation challenges, the data landscape, and what the patient experience might look like. If you liked this episode, l…
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Protecting the Golden Age of Medicine with John Crowley
30:33
30:33
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30:33John Crowley, President and CEO of Biotechnology Innovation Organization (BIO), joined Jorge Conde, general partner at a16z Bio + Health. Together, they talk about John’s entry into biotech and his time as a founder, all motivated by his determination to discover and develop a treatment for his children, who have Pompe disease. They also talk about…
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A Fatal Inheritance with Lawrence Ingrassia
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28:05
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28:05Lawrence Ingrassia, author and journalist, joins Vineeta Agarwala, general partner, and Kris Tatiossian, editorial lead at a16z Bio + Health. Together, they discuss Larry's recently published book, A Fatal Inheritance: How A Family Misfortune Revealed A Deadly Medical Mystery. In the book, Larry recounts the story of the p53 cancer suppressor gene,…
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Network Medicine with Jonathan Swerdlin and Mark Hyman
33:14
33:14
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33:14Jonathan Swerdlin, cofounder and CEO, and Mark Hyman, MD, cofounder and Chief Medical Officer of Function Health join Vijay Pande, general partner, and Daisy Wolf, investment partner of a16z Bio + Health. Together, they discuss their personal health journeys that led to founding Function, how they’re planning to scale Function, and what the future …
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Regulation as a Catalyst with Jonathan Bush and Chris Severn
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37:08
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37:08Jonathan Bush, founder and CEO of Zus Health, and Chris Severn, cofounder and CEO of Turquoise Health, join Julie Yoo, general partner, and Colin Rom, head of public policy for a16z Bio + Health. We’ve long believed that regulatory change can be a catalyst for company creation. In this episode, Jonathan and Chris detail how that was true for them. …
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The Transformative Power of AI in Science with Pushmeet Kohli
56:25
56:25
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56:25In this episode, originally recorded for the a16z Podcast, host Steph Smith interviews Pushmeet Kohli, DeepMind's VP of Research focused on AI for science. They are joined by a16z Bio + Health founding partner Vijay Pande. Together, they discuss AI at scale, and its power to transform science.By Pushmeet Kohli, Olivia Webb, Vijay Pande, Kris Tatiossian, Steph Smith
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The Science and Supply of GLP-1s with Chronis Manolis
31:30
31:30
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31:30Chronis Manolis, SVP and Chief Pharmacy Officer of UPMC Health Plan, joins Julie Yoo, general partner, Daisy Wolf, investment partner, and Will Shrank, venture partner, of a16z Bio + Health. Together, they discuss how payors and providers are thinking about anti-obesity medications, as well as pricing and prior authorization considerations. This is…
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The Science and Supply of GLP-1s with Brooke Boyarsky Pratt
42:53
42:53
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42:53Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health. Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time. This is the second episode in our series on the science and…
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The Science and Supply of GLP-1s with Carolyn Jasik
29:42
29:42
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29:42Carolyn Jasik, MD, Chief Medical Officer of Omada Health, joins Vijay Pande, founding partner of a16z Bio + Health. As Ozempic, Wegovy, Mounjaro, and Zepbound capture the healthcare spotlight, we’ve developed a series of episodes that go beyond the headlines and take you into conversations with the specialists. Our first guest is Carolyn Jasik, Chi…
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The Intersection of Biotech x High Tech with Vineeta Agarwala
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57:09
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57:09Vineeta Agarwala, MD, PhD, joins Luke Timmerman's The Long Run podcast on stage at the Life Science Innovation Northwest Conference. They discuss everything from AI for drug discovery to Vineeta's ongoing clinical work as a physician and how that influences her perspective.By Luke Timmerman, Kris Tatiossian, Vineeta Agarwala, Olivia Webb
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AI in Pharmaceutical R&D with Kim Branson
31:15
31:15
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31:15Kim Branson, PhD, SVP and Global Head of AI and Machine Learning for GSK, joins Vijay Pande, founding partner at a16z Bio + Health. Together, they talk about how AI has improved drug discovery and development, as Kim walks through all the ways AI can be deployed in the lab. They also get into detail about what an ideal partner looks like and what k…
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In this episode, Carl June, MD, pioneering immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, they discuss Carl's work on CAR T, a remarkable story of the first use of CAR T in a pediatric patient, and Carl's take on where oncology treatments are headed next. Though this…
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Longevity as a Health Asset with Tom Hale
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27:54
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27:54Tom Hale, CEO of ŌURA, joins Vijay Pande, founding partner, and Daisy Wolf, investment partner at a16z Bio + Health. Together, they talk about the potential of wearables to change behavior, and how that can affect health. They also discuss how AI could maximize the usefulness of wearables and power the insights provided to wearers.…
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The Power of Drug Discovery with Philip Tagari
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31:36Philip Tagari, Chief Scientific Officer of insitro, joins Vijay Pande, founding general partner at a16z Bio + Health. Together, they discuss the transformative power of drugs in changing human health—and history. They also reflect on the evolution of the drug discovery process as it shifts from serendipitous discovery to AI-enabled engineering. Fin…
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AI-Enabled Continuity of Care with Ed and Todd Park
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25:41Vijay Pande, founding general partner of a16z Bio + Health, chats with the builders (and siblings) behind Devoted Health, Ed and Todd Park. The Park brothers, with decades of expertise in healthcare and policy, including as EVP and COO at athenahealth (Ed) and Chief Technology Officer of the United States (Todd), started Devoted with the idea of bu…
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Grand Challenges in Healthcare AI with Vijay Pande and Julie Yoo
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38:33Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to talk through the grand challenges facing healthcare AI today. The discussion covers the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the potential for innovation in clinical tri…
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Adapting Biopharma to AI with Greg Meyers
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33:30Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb (or BMS), joins a16z Bio + Health general partner Jorge Conde. Together, they talk about how AI could transform drug discovery and development at a large biopharma company—and how a company might have to adapt to harness AI; modalities they’re excited about; and Greg’…
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Behind the Buy: Payors and Providers on AI Adoption
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23:51
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23:51As any healthcare founder knows, it can be difficult to get into a room with the executives making purchase decisions for payors and providers—so we’re bringing the executives to you. This episode features interviews with payor and provider leaders about what they’re seeing and how they’re thinking about AI. Guided by Julie Yoo, general partner, an…
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Biotech Revolution with Software Engineering Daily
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54:12
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54:12"There is a revolution unfolding in biotech. The confluence of new biological methods like CRISPR, virtually unlimited computational capacity, and machine learning has fundamentally transformed our ability to engineer biology for wide-ranging applications." Vijay Pande, founding general partner at a16z Bio + Health, joins the Software Engineering D…
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Dark Genome Hunting with Rosana Kapeller and Marty Taylor
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38:18Rosana Kapeller, CEO of Rome Therapeutics, and Marty Taylor, physician-scientist at Harvard Medical School, join Vineeta Agarwala, general partner, and Bryan Faust, investment partner at a16z Bio + Health. Together, they discuss Rosana and Marty's recent publication regarding a virus-like element in our genome known as LINE-1. LINE-1, part of our "…
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Vijay Pande, founding partner of a16z Bio + Health, dives deep with a16z Podcast host Steph Smith into the potential of DNA as a data storage mechanism. This episode, a cross-post with the a16z Podcast, draws parallels between Moore's Law and the race for "Moore's Law for DNA." Vijay discusses the density, longevity, and ubiquity of DNA, and how th…
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The Most Interesting Healthcare Companies You've Never Heard Of with Julie Klapstein
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28:20Julie Klapstein, founding CEO of Availity, long-time healthcare executive, and a16z Bio + Health's newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health. Together, they delve into Julie Klapstein's rich career journey, which has spanned several decades of progress in healthcare. They also discussed building Availity, her ti…
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Scribe Therapeutics cofounder and CEO Benjamin Oakes, PhD, joins a16z Bio + Health founding general partner Vijay Pande. In this episode, Benjamin traces his journey from PhD student to pioneering CEO in genome editing. Benjamin discusses his early exposure to CRISPR technologies, his hands-on experience of transforming these bacterial immune syste…
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Metrics for a Complex Machine with Josh Clemente
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27:58Josh Clemente, cofounder and president of Levels, joins Vijay Pande, founding general partner, and Daisy Wolf, investment partner at a16z Bio + Health. In this episode, engineer-turned-entrepreneur Josh charts his journey from SpaceX and Hyperloop to cofounding metabolic health-focused company Levels. With a relentless drive for data-led health mon…
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Transitioning From Gymnast to Investor with Aly Raisman
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27:24Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health. In this episode, Aly Raisman shares her quest for healthier living—physically, mentally and financially—on her journey from gymnast to a business investor. Having herself transitioned from an intensely structured r…
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