Stephen Wolfram is the creator of Mathematica, Wolfram|Alpha and the Wolfram Language; the author of A New Kind of Science; and the founder and CEO of Wolfram Research. Over the course of nearly four decades, he has been a pioneer in the development and application of computational thinking—and has been responsible for many discoveries, inventions and innovations in science, technology and business. On his podcast, Stephen discusses topics ranging from the history of science to the future of ...
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Wolfram Research Podcasts
Host Gatley Stone interviews some of NC State’s most distinguished professors to learn about their research and how they made it to where they are today. This series is made possible thanks to NC State's student radio station, WKNC 88.1 FM HD-1/HD-2.
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A podcast about diabetes and genes hosted by Andrew Hattersley and Maggie Shepherd.
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A regular series exploring issues related to sustainable development and economic justice in low and middle income countries. Produced by the Economic Growth Center at Yale University.
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It Happened To Me: A Rare Disease and Medical Challenges Podcast
Cathy Gildenhorn, Beth Glassman, and Kira Dineen (DNA Today)
The mission of our podcast is to support you, our listeners and to create community, as you confront the toughest challenges in life. All of us will experience health hardships. The real question is how we adapt. That is the focus of It Happened To Me, which wants to help you overcome limitations and live a full and satisfying life. Drawing on their own health challenges, hosts Cathy Gildenhorn and Beth Glassman interview guests who share stories and research to help you succeed in the face ...
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Science & Technology Q&A for Kids (and others) [July 25, 2025]
1:10:33
1:10:33
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1:10:33Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: The Big Bang and expansion of space - Mathematics and physical reality - Computational foundations of biology - The role of kids in science and tec…
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History of Science & Technology Q&A (July 23, 2025)
1:22:37
1:22:37
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1:22:37Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: Historical scientific problems and modern computation - Historical contingency in technology - Online Encyclopedia of Integer Sequences (OEI…
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Future of Science and Technology Q&A (July 18, 2025)
1:16:43
1:16:43
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1:16:43Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics discussed: Personalized pedagogy and AI in education - Computer simulations vs. physical experimentation - Aging and longevity science AI, con…
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Business, Innovation and Managing Life (July 16, 2025)
1:04:52
1:04:52
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1:04:52Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Topics discussed: Using AI in daily work and research - Interfaces and the adoption of AI technology - Computation and the future of algo…
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Series 4 Episode 2. Rachel Besser. Identifying children before they develop Type 1 diabetes
24:24
24:24
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24:24Dr Rachel Besser explains how new treatment options means it is now important to identify children before they get symptomatic Type 1 diabetes. Rachel is working to make sure testing for risk of Type 1 diabetes is done in the best way for children and their families. Send us a textBy Andrew Hattersley and Maggie Shepherd
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#64 Challenging the Label: Living and Thriving with Trisomy 18 Part 2
31:23
31:23
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31:23In this second part of our interview with Sartia Edwards, we continue a conversation about her son Elijah, who lives with Full Trisomy 18, also known as Edwards Syndrome. Sarita Edwards, MHA is the CEO & President at the E.WE Foundation, a global healthcare advocacy organization for families living with Trisomy 18 (Edwards Syndrome) and other rare …
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History of Science & Technology Q&A (July 2, 2025)
1:38:09
1:38:09
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1:38:09Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: Alternate histories and missed scientific paths - How science is remembered and talked about - Scientific breakthroughs - How science gets d…
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Series 4 Episode 1. Richard Oram. First steps towards preventing Type 1 diabetes
24:28
24:28
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24:28Richard Oram explains how recent advances have meant we can now delay type 1 diabetes with immunotherapy. To do this we need to be able to identify people at very high risk of developing Type 1 diabetes. Richard thinks genetic analysis could play a part in this identification. Send us a textBy Andrew Hattersley and Maggie Shepherd
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#63 Redefining “Incompatible with Life”: A Mother’s Mission for Trisomy 18 Awareness Part 1
35:19
35:19
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35:19In this powerful episode of It Happened To Me, co-hosts Cathy and Beth sit down with Sarita Edwards, an award-winning advocate, rare disease leader, and mother to Elijah, who lives with Full Trisomy 18, also known as Edwards Syndrome. Sarita Edwards, MHA is the CEO & President at the E.WE Foundation, a global healthcare advocacy organization for fa…
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Science & Technology Q&A for Kids (and others) [June 20, 2025]
1:20:27
1:20:27
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1:20:27Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: Black hole mergers, event horizons and why nothing gets out - Time dilation and computing near black holes - Ions…
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Series 3 Episode 17. Jennifer and Helen. Prader Willi syndrome: hunger that never goes away
33:22
33:22
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33:22Jennifer and her mother Helen explain how being born Prader Willi syndrome has had a lifelong impact. One challenge is that Jennifer is continually hungry, and so limiting access to food is needed at all times. Send us a textBy Andrew Hattersley and Maggie Shepherd
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Future of Science and Technology Q&A (June 13, 2025)
1:26:18
1:26:18
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1:26:18Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics discussed: The limits and future of software defined everything - Molecular design and biological engineering - Human enhancement and genome l…
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Development Dialogues: What is the role of small farms in the future of agriculture?
33:59
33:59
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33:59In this episode of Development Dialogues, a panel of experts dissect one of Africa’s most persistent development challenges: the low productivity of smallholder farmers. Despite decades of investment, innovation, and policy reform, yields on African small farms remain significantly below those in high-income countries—even when similar technologies…
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Business, Innovation and Managing Life (June 11, 2025)
1:26:35
1:26:35
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1:26:35Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Topics discussed: Wolfram Summer School - Computational thinking and education - Parenting and learning from family - Project habits, cur…
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#62 Vision Through Music: Empowering Visually Impaired Kids with Adaptive Music Education
38:38
38:38
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38:38In this inspiring episode, we’re exploring the powerful intersection of music and accessibility with three incredible guests: Dr. Bradley Black, a world-renowned pediatric ophthalmologist and founder of the Vision Through Music program, Makayla, a passionate young musician and student in the program, and Maykaya’s mother Joann. Dr. Bradley Black (h…
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History of Science & Technology Q&A (June 4, 2025)
1:22:42
1:22:42
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1:22:42Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: AI milestones and conceptual shifts - Encounters with physicists - Attributes and personalities of influential thinkers - Naming conventions…
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Special episode 7. Maggie Shepherd (part 2). Inspirational nurse researcher and educator
28:59
28:59
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28:59Professor Maggie Shepherd reflects back on her career and how she made the massive steps from being a clinical nurse to becoming a nationally leading researcher and educator. Send us a textBy Andrew Hattersley and Maggie Shepherd
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#61 How Jack’s Basket Is Changing the Down Syndrome Diagnosis Story
43:19
43:19
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43:19In this heartfelt episode we welcome guest Carissa Carroll, M.Ed., Founder and Executive Director of Jack’s Basket, a nonprofit that has transformed the way families experience a Down syndrome diagnosis. A former educator with degrees from Bethel University and the University of Minnesota, Carissa taught at both the elementary and collegiate levels…
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What If We Had Bigger Brains? Imagining Minds beyond Ours
1:54:38
1:54:38
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1:54:38Stephen reads a recent blog from https://writings.stephenwolfram.com and then answers questions live from his viewers. Read the blog along with Stephen https://writings.stephenwolfram.com/2025/05/what-if-we-had-bigger-brains-imagining-minds-beyond-ours/ Watch the original livestream on YouTube: https://youtu.be/qUIj_t-YbIk…
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Stephen reads a blog from https://writings.stephenwolfram.com and then answers questions live from his viewers. Read the blog along with Stephen: https://writings.stephenwolfram.com/2023/12/observer-theory/ Watch the original livestream on YouTube: https://youtu.be/qm3Y6qxdOwM
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Special episode 6. Andrew Hattersley (part 2). Building the Exeter diabetes research team
29:54
29:54
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29:54Andrew Hattersley describes how teamwork and mutual support has helped the Exeter diabetes research team expand and flourish over the past 30 years Send us a textBy Andrew Hattersley and Maggie Shepherd
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Future of Science and Technology Q&A (May 16, 2025)
1:11:48
1:11:48
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1:11:48Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics discussed: Copyright and creative ownership in an AI world - AI built into personal systems - Data scraping, consent and privacy tradeoffs - A…
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Science & Technology Q&A for Kids (and others) [May 9, 2025]
1:09:05
1:09:05
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1:09:05Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: Conscious experience and perception - Brain structure and sensory extension - Brain manipulation and individuality - Consciousness and artificial s…
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Business, Innovation and Managing Life (May 14, 2025)
1:28:44
1:28:44
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1:28:44Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Topics discussed: Building companies that do real science - New frontiers in science, complex systems and generative art - Risks of algor…
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#60 CRISPR, Community, and Courage: A Deep Dive into Sickle Cell Advocacy
36:25
36:25
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36:25In this powerful episode of It Happened To Me, co-hosts Cathy Gildenhorn and Beth Glassman are joined by two fierce patient advocates and changemakers in the sickle cell disease community: Wunmi Bakare and Dima Hendricks. Both women are living with sickle cell disease and have transformed their lived experiences into platforms for storytelling, edu…
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Series 3 Episode 16. Grace Bervoets and Amanda Stride. Cystic Fibrosis related Diabetes
32:24
32:24
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32:24Grace Bervoets talks about living with cystic fibrosis and cystic fibrosis related-diabetes. Amanada Stride, who works as a diabetes consultant helping people with cystic fibrosis related-diabetes, explains the many challenges of this unusual type of diabetes. Send us a text
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History of Science & Technology Q&A (May 7, 2025)
1:21:29
1:21:29
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1:21:29Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics: Studying the history of science - Contradictions and accuracy in historical research - History of memory research - Planck's constant…
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Future of Science and Technology Q&A (May 2, 2025)
1:10:14
1:10:14
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1:10:14Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Topics discussed: Fusion energy and nuclear fuel design - AI reasoning, learning and scientific roles - Mathematics, computation and physical reality…
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Business, Innovation and Managing Life (April 30, 2025)
1:13:27
1:13:27
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1:13:27Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Topics discussed: Starting and funding a biotech company - Thinking clearly and building ideas from scratch - Getting better at asking qu…
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History of Science & Technology Q&A (April 23, 2025)
1:24:04
1:24:04
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1:24:04Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: Do you know anything about the history of vaccines? When was the first vaccine developed and for what? - Isn't some important par…
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Science & Technology Q&A for Kids (and others) [April 18, 2025]
1:21:53
1:21:53
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1:21:53Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: Books have been relatively unchanged—would you say that's a "technology" that has been mastered? - My son asks: Given there's a max amou…
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