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EP Edge

Niraj Sharma MD FACC FHRS

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EP-EDGE brings you the latest in cardiac electrophysiology — from breakthrough research and clinical insights to future-shaping innovations. Hosted by Dr. Niraj Sharma, an electrophysiologist with over 15 years of experience, each episode delivers clear, evidence-based updates designed to inform, inspire, and elevate your practice.
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EP Edge Journal Watch

Niraj Sharma MD FACC FHRS

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Welcome to EP Edge Journal Watch — where cardiac electrophysiology meets evidence, precision, and perspective. Hosted by Dr. Niraj Sharma, this bi-weekly podcast distills high-impact cardiovascular and EP research into clear, clinically meaningful insights. Each episode goes beyond headlines and abstracts to uncover what new studies actually mean for patient care, decision-making, and the future of electrophysiology. What EP Edge Journal Watch stands for: Evidence-based practice Precision el ...
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EP Edge Heart Talk

Niraj Sharma MD FACC FHRS

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EP-EDGE Heart Talk is a patient-focused cardiology podcast created and hosted by Dr. Niraj Sharma, MD, FACC, FHRS—a board-certified cardiologist and cardiac electrophysiologist dedicated to helping patients and caregivers understand their heart rhythm conditions with clarity and confidence. This podcast breaks down complex heart rhythm issues into simple, practical conversations you can trust. Each episode explores topics such as atrial fibrillation (AFib), palpitations, PVCs, SVT, ventricul ...
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Mastering the 12 Lead EKG

Mastering the 12 Lead EKG

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Lectures recorded by Mastering the 12 Lead EKG author, David Roberts, during EKG Interpretation course in the Bethel University Physician Assistant program. Recorded Summer Semester 2015 and 2017.
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The Cardiovascular CME podcast is a free educational offering from Mayo Clinic, featuring content geared towards physicians, physician assistants, and nurse practitioners who are interested in exploring a multitude of cardiology-related topics. Tune in and subscribe to explore today’s most pressing cardiology topics with your colleagues at Mayo Clinic and gain valuable insights that can be directly applied to your practice. No CME credit offered for podcast episodes at this time.
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Heart Podcast

BMJ Group

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The Heart Podcast is your go-to source for the latest insights and developments in cardiovascular medicine. Each episode features in-depth interviews with renowned authors and leading experts in the field, delving into the latest advances in cardiovascular research and treatments. Heart - heart.bmj.com - is a renowned international journal from the BMJ Group and the British Cardiovascular Society (BCS) dedicated to publishing research and reviews on cardiovascular disease. Stay ahead in your ...
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The Internet Book of Critical Care Podcast

Adam Thomas & Josh Farkas

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Brought to you by a partnership that transcends the 49th parallel. Join Adam Thomas and Josh Farkas in the podcast that accompanies The Internet Book of Critical Care. The IBCC podcast will explore key points in each chapter. Initially the release of podcasts may lag a bit behind the chapters for logistic reasons. However, our goal is to eventually have a podcast for each chapter. Subsequently, the podcast will discuss updates to the IBCC based on new evidence.
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Venugopal Menon, MD, Director of the Coronary ICU, and Michael Tong, MD, cardiothoracic surgeon specializing in advanced heart failure, discuss contemporary management of post-infarction ventricular septal rupture, a rare but serious complication. They review the role of early transfer to high-volume centers and why definitive surgical closure rema…
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In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr John Sapp from Halifax, Nova Scotia, Canada. They discuss his review paper all about ventricular tachycardia in terms of drug and device therapies, plus advances in VT ablation. If you enjoy the show, please leave us a positive review wherever you get …
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Global Practices in Cardiac Imaging for Cardiac Sarcoidosis Guest: Tahir Kafil, M.D. Host: Sharonne Hayes, M.D. Cardiac imaging is a cornerstone in the diagnostic work-up and management of cardiac sarcoidosis. However, indications and use of advanced cardiac imaging vary from institution to institution, and even between providers at the same instit…
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Join Amar Krishnaswamy, MD, Head of Interventional Cardiology, and Marijan Koprivanac, MD, Cardiac Surgeon at Cleveland Clinic, as they discuss what patients can expect after aortic valve replacement, whether surgical or transcatheter. Learn about minimally invasive techniques, recovery timelines and the critical role of cardiac rehab and follow-up…
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EP Edge Journal Watch — January 2026 | Issue #5 Pulsed Field Ablation, Device Therapy, and the Era of Personalized EP Welcome to EP Edge Journal Watch – Issue #5 (January 2026), your high-yield, evidence-driven electrophysiology podcast designed for practicing EPs who want more than just abstracts. As 2026 begins, electrophysiology is entering a de…
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Have you or a loved one been diagnosed with an abdominal aortic aneurysm (AAA)? You're not alone, and you're in the right place. In part two of this two part series, Cleveland Clinic’s vascular experts discuss surgery and less-invasive repair techniques, the recovery experience and how to recognize the signs of an aortic rupture. Learn more about a…
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Anticoagulation Monotherapy in Patients with Chronic Coronary Artery Disease and Atrial Fibrillation Guest: Keri Zieminski, APRN, C.N.P., D.N.P. Host: Sharonne Hayes, M.D. This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of anticoagulation monotherapy in patients with chronic CAD and atrial fibrillation. Discussion …
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In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Professor Michelle Williams from the University of Edinburgh. They discuss the possibility of predicting cardiovascular disease on CT from clinical factors in the SCOT-HEART trial. If you enjoy the show, please leave us a positive review wherever you get …
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Updated Guidelines for Perioperative Cardiovascular Management for Noncardiac Surgery Guest: Michael Cullen, M.D. Host: Kyle Klarich, M.D. This episode of Mayo Clinic’s “Interviews With the Experts” reviews the assessment of patients with known or suspected cardiovascular disease undergoing noncardiac surgery. Dr. Michael Cullen discusses recommend…
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In this EP-EDGE podcast episode, Dr. Niraj Sharma, cardiac electrophysiologist, breaks down the latest evidence linking modern high-THC cannabis to cardiovascular and electrophysiologic risk. Drawing from large real-world datasets, mechanistic studies, and global meta-analyses, this episode explains how today’s cannabis products—vapes, edibles, dab…
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In our latest episode, Deputy Editor Dr. Zam Kassiri (University of Alberta) interviews authors Dr. German González (Pontificia Universidad Católica Argentina), Dr. Rebecca Ritchie (Monash University), Dr. Pooneh Bagher (University of Nebraska Medical Center), and Dr. Hiroe Toba (Kyoto Pharmaceutical University) about the latest Guidelines in Cardi…
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Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The ep…
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In this December 2025 episode of EP Edge Journal Watch, Dr. Niraj Sharma breaks down the most provocative atrial fibrillation trials of the year—studies that force us to rethink what really drives AF outcomes beyond the ablation lesion EP EDGE JW Dec 2025 Newsletter. We dive deep into four game-changing themes shaping modern electrophysiology: Can …
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Have you or a loved one been diagnosed with an abdominal aortic aneurysm (AAA)? You're not alone, and you're in the right place. In part one of this two part series, Cleveland Clinic’s vascular experts answer questions that real patients asked about abdominal aortic disease. Learn about aneurysm risk factors, genetic links to aortic disease and how…
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Obesity, Hypertension, and Risk Factors in Terms of Prevention and Decreasing the Risk of HfpEF Guest: Affan Irfan, M.D., Ph.D. Host: Stephen L. Kopecky, M.D. HFpEF is a type of heart failure where the heart pumps normally but becomes stiff. This leads to fatigue, shortness of breath, and fluid retention. It is closely linked to obesity, hypertensi…
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Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence…
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Hani Najm, MD, and Joanna Ghobrial, MD, explain the latest advances in transcatheter pulmonary valve implantation, surgical strategies and lifetime management. Learn how a multidisciplinary approach helps patients live longer, healthier lives with fewer interventions. Schedule an appointment at Cleveland Clinic by calling 844.868.4339. Subscribe to…
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Aortic Regurgitation: Beyond the Valve Guest: Vidhu Anand, M.B.B.S. Host: Kyle Klarich, M.D. In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Klarich and Dr. Anand discuss evolving approaches to assessing left ventricular remodeling in chronic aortic regurgitation. Dr. Vidhu Anand discusses research showing that LV volumes, globa…
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Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-bas…
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Venugopal Menon, MD, and Michael Tong, MD, explain how modern advances are transforming treatment for a rare but life-threatening complication after a heart attack: ventricular septal rupture. Learn why early transfer to an expert center matters, how mechanical support devices buy time for recovery and why surgery remains the definitive solution fo…
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Presentation, Evaluation, and Management of Premature Ventricular Contractions Guest: Alan M. Sugrue, M.B., B.Ch., B.A.O. Host: Anthony H. Kashou, M.D. In this episode, Dr. Anthony Kashou and Dr. Alan Sugrue cover a practical, evidence-based approach to premature ventricular contractions (PVCs), from incidental findings to high-burden, high-risk pr…
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In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr William Parker from Sheffield in the UK. They discuss how PCI has changed over the last 40 years, covering balloons, stents, drugs and the future. If you enjoy the show, please leave us a positive review wherever you get your podcasts. It helps us to r…
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Smartwatches are now among the most widely used heart-monitoring tools in the world — but how accurate are they really at detecting AFib? In this December 2025 Issue 3 of EP-Edge Journal Watch, Dr. Niraj Sharma, cardiologist and cardiac electrophysiologist, breaks down the strongest evidence to date on smartwatch AFib detection, Apple Watch ECG per…
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Smartwatches & AFib: What Your Wrist Can—and Can’t—Tell You About Your Heart Smartwatches are changing the way millions of people discover heart rhythm problems—especially atrial fibrillation (AFib). But how accurate are devices like the Apple Watch, Fitbit, Samsung Galaxy Watch? And what should you actually do if your watch alerts you to an irregu…
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A-Fib Rhythm Control Explained: Cardioversion, Medications, and Ablation — What Patients Need to Know Managing atrial fibrillation (A-Fib) goes far beyond simply slowing the heart rate. In this episode of EP-EDGE Heart Talk, Dr. Niraj Sharma—cardiologist and cardiac electrophysiologist—breaks down everything patients and caregivers need to understa…
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Atrial fibrillation—also known as AFib—is the most common heart rhythm disorder worldwide, and understanding it early can dramatically improve long-term outcomes. In this episode of EP-EDGE Heart Talk, Dr. Niraj Sharma breaks down AFib in a simple, clear, and empowering way designed specifically for patients and caregivers. You’ll learn: What atria…
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Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatmen…
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A new Cleveland Clinic study uncovered how gut health could influence serious vascular conditions. Stanley Hazen, MD, PhD, and Scott Cameron, MD, PhD, explain the surprising link between the gut microbiome, TMAO levels and abdominal aortic aneurysms. Learn about emerging research, lifestyle strategies and future treatments that could transform card…
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Tricuspid Regurgitation: New Insights and Implications for Clinical Practice Guest: Vidhu Anand, M.B.B.S. Host: Kyle Klarich, M.D. This episode of Mayo Clinic’s “Interviews With the Experts,” explores new insights into tricuspid regurgitation and its implications for clinical practice. Dr. Vidhu Anand discusses the dynamic nature of TR, its impact …
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Why is a broad approach that works with iPSC-derived cardiomyocytes so important to understanding molecular mechanisms underlying calcium homeostasis and arrhythmias? In this episode, Associate Editor Dr. Petra Kleinbongard (University of Duisburg-Essen) interviews author Dr. Katrin Streckfuss-Bömeke (University Medical Center Göttingen) and expert…
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In this issue, we trace the fascinating evolution of atrial fibrillation (AF) therapy — from the Cox Maze procedure to Haïssaguerre’s discovery of pulmonary vein ectopy, through Pappone’s wide antral isolation, and onward to the era of pulse field ablation (PFA). We explore how ablation technologies have transformed — radiofrequency, cryo, and PFA …
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Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.…
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Discover how a multidisciplinary team tackles peripheral artery disease (PAD) with a patient-first approach. Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, share how collaborative care across vascular medicine, vascular surgery and cardiology leads to better outcomes and lifelong management. Get treatment for PAD at Clevela…
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Cardiovascular Diet Myths Guest: Stephen Kopecky, M.D. Host: Sharonne Hayes, M.D. Since 2018, Trans-Fats are prohibited from being a food additive in the US. In this episode of “Interviews With the Experts,” Dr. Stephen Kopecky discussed how trans fats are still in our food, just not as much as pre-2018, and the main sources of trans fat are ultra-…
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In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr Frances Varian from the University of Sheffield, UK. They discuss her insights as a cardiologist and geography graduate working in the NHS with respect to the environmental impact of climate change on our health. Dr Varian is leading the British Cardio…
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What is the main driver of sex differences in heart failure with reduced ejection fraction (HFrEF)? In our latest episode, Associate Editor Dr. Petra Kleinbongard (University of Duisburg-Essen) interviews lead author Dr. Matthieu Ruiz (Montreal Heart Institute) and expert Dr. Catherine Mounier (Université du Québec à Montréal) about the new study b…
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Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management. Learn more about C5 Research…
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Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce the Cardioimmunology Center. They explore how immune system activity can influence heart health and discuss innovative approaches to identifying and managing cardiovascular risk through imm…
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Evolving Treatment Landscape in Transthyretin Cardiac Amyloidosis Guest: Rosalyn Adigun, M.D., Pharm.D. Host: S. Allen Luis, M.B.B.S., Ph.D. In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Allen Luis interviews Dr. Rosalyn Adigun on transthyretin cardiac amyloidosis. Listeners will come away with a detailed overview of the evolu…
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In this special EP Edge Journal Watch episode, Dr. Niraj Sharma delivers a critical analysis of the landmark AQUATIC Trial, published in the New England Journal of Medicine (October 2025). This pivotal study explores optimal antithrombotic strategies in patients with atrial fibrillation (AF) and coronary artery disease (CAD) — balancing ischemic pr…
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A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes. Looking to refer …
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Lars Svensson, MD, PhD, and Xiaoying Lou, MD, discuss valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms. They explain who qualifies for this procedure, how it’s performed and why it can offer long-term benefits without lifelong blood thinners. Learn more about aortic v…
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