Best Vasodilation Podcasts (2026)

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Antihypertensives Test Prep and Practice Pearls; Part 3 – Aldosterone Antagonists and Vasodilators 14:28

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2h ago14:28

14:28

Aldosterone antagonists, such as spironolactone and eplerenone, are potassium-sparing diuretics that block aldosterone at the mineralocorticoid receptor in the distal nephron. By reducing sodium and water reabsorption while conserving potassium, they play a key role in heart failure, resistant hypertension, and primary hyperaldosteronism. Clinicall…

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Pimavanserin Pharmacology Podcast 12:53

9h ago12:53

12:53

Pimavanserin is an atypical antipsychotic approved for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. Unlike traditional antipsychotics, it does not block dopamine receptors, making it a unique option for patients with Parkinson’s disease who are highly sensitive to dopamine antagonism. Mechanism of Act…

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Antihypertensives Test Prep and Practice Pearls; Part 2 – ARBs and Thiazides 16:43

7d ago16:43

16:43

This podcast is designed to help pharmacy and nursing learners cut through the noise and focus on the high-yield concepts that matter most when it comes to angiotensin receptor blockers (ARBs) and thiazide diuretics. These two medication classes show up constantly on exams and in clinical practice, yet small details about their mechanisms, adverse …

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Antihypertensives Test Prep and Practice Pearls; Part 1 – ACEIs and CCBs 13:03

14d ago13:03

13:03

Welcome to today’s episode, where we dive into two cornerstone classes of antihypertensives: ACE inhibitors and calcium channel blockers. These drugs are among the most frequently prescribed agents in both primary care and specialty settings, making a solid understanding of their practical nuances essential for clinicians, pharmacists, and learners…

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Moxifloxacin Pharmacology 14:47

21d ago14:47

14:47

Moxifloxacin is a fourth-generation fluoroquinolone that works by inhibiting bacterial DNA gyrase and topoisomerase IV—two enzymes essential for DNA replication, repair, and transcription. By blocking both targets, it provides broad-spectrum activity against gram-positive, gram-negative, and atypical pathogens. Its enhanced gram-positive coverage, …

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Albuterol Pharmacology 17:29

28d ago17:29

17:29

On this episode of the Real Life Pharmacology Podcast, I cover albuterol pharmacology, adverse effects, and a rare indication for this classic respiratory medication. Albuterol is a short-acting beta-2 adrenergic agonist (SABA) that works by stimulating beta-2 receptors in the bronchial smooth muscle. This stimulation activates adenylate cyclase, i…

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Glycopyrrolate Pharmacology 11:47

1M ago11:47

11:47

Glycopyrrolate is an anticholinergic medication commonly used to reduce excessive secretions, particularly in palliative care, postoperative settings, and certain neurologic conditions. It works by blocking acetylcholine at muscarinic receptors, which decreases salivary and respiratory secretions. Clinically, glycopyrrolate is often used to manage …

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Bisacodyl (Dulcolax) Pharmacology 15:53

1M ago15:53

15:53

Bisacodyl, commonly known by the brand name Dulcolax, is a stimulant laxative widely used for short-term relief of constipation and bowel preparation before procedures. It works by directly stimulating the enteric nerves in the colon, increasing peristalsis, and promoting bowel evacuation. Mechanism of Action: Bisacodyl acts primarily on the large …

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Fludrocortisone (Florinef) Pharmacology 14:44

2M ago14:44

14:44

On this podcast episode, I cover fludrocortisone. Fludrocortisone is a synthetic corticosteroid with potent mineralocorticoid activity and minimal glucocorticoid effects. It works primarily by promoting sodium reabsorption and potassium excretion in the distal renal tubules, leading to increased water retention and expansion of extracellular fluid …

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10 Common Examples of The Prescribing Cascade 13:46

2M ago13:46

13:46

One of the most important yet often overlooked concepts in pharmacology is the prescribing cascade. It occurs when a new medication is prescribed to treat a side effect caused by another drug, without realizing that the first medication is the root cause. This leads to a chain reaction of additional prescriptions, unnecessary complexity, and often,…

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Airsupra (Albuterol/budesonide) Pharmacology 11:54

2M ago11:54

11:54

Airsupra is a combination inhaler that contains albuterol and budesonide, approved for as-needed use in adults with asthma. It represents the first rescue inhaler to combine a short-acting beta-2 agonist (SABA) with an inhaled corticosteroid (ICS) in a single device. The albuterol component provides rapid bronchodilation by relaxing airway smooth m…

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Daptomycin Pharmacology 14:49

2M ago14:49

14:49

In this episode of Real Life Pharmacology, we take a deep dive into daptomycin, a lipopeptide antibiotic primarily used for serious Gram-positive infections, including MRSA and VRE. Daptomycin works by binding to bacterial cell membranes in a calcium-dependent manner, causing rapid depolarization and cell death. One key limitation is that daptomyci…

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Cefepime Pharmacology 12:28

3M ago12:28

12:28

Cefepime is a fourth-generation cephalosporin antibiotic with broad-spectrum activity against both gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. It works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to cell lysis and death. Clinically, cefepime is commonly used in…

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Midodrine Pharmacology Podcast 12:11

3M ago12:11

12:11

Midodrine is an oral alpha-1 agonist most commonly used for the treatment of symptomatic orthostatic hypotension. Its mechanism of action is through peripheral vasoconstriction, which helps increase blood pressure. Because of its short duration of action, it is typically dosed three times daily, with the last dose recommended in the late afternoon …

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Piperacillin/Tazobactam Pharmacology 13:18

3M ago13:18

13:18

Zosyn (piperacillin/tazobactam) is a broad-spectrum β-lactam/β-lactamase inhibitor combination used widely in hospitals. Piperacillin covers gram-positive, gram-negative, and anaerobic bacteria, while tazobactam helps protect against β-lactamase breakdown. It is commonly used for pneumonia, intra-abdominal infections, skin and soft tissue infection…

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Senna Pharmacology 14:07

3M ago14:07

14:07

Senna is a stimulant laxative. Its pharmacological activity comes from natural compounds called sennosides. Metabolites act locally in the colon to stimulate peristalsis, thereby accelerating bowel movements. While osmotic laxatives are generally considered first-line laxative agents, this makes senna a useful alternative for the short-term treatme…

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Revefenacin Pharmacology Podcast 13:11

4M ago13:11

13:11

Revefenacin (brand name Yupelri) is a long-acting muscarinic antagonist (LAMA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD). It works by blocking muscarinic receptors, particularly the M3 subtype, in airway smooth muscle. This antagonism reduces cholinergic bronchoconstriction and leads to sustained bronchodila…

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Desmopressin Pharmacology Podcast 14:10

4M ago14:10

14:10

Desmopressin is a synthetic analog of vasopressin, also known as antidiuretic hormone (ADH). It works by mimicking the action of natural ADH on the kidneys, primarily increasing water reabsorption in the collecting ducts. This effect reduces urine production and helps concentrate the urine. Because of this mechanism, desmopressin is commonly used i…

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Ciprofloxacin Pharmacology Podcast 16:10

4M ago16:10

16:10

On this podcast, I cover ciprofloxacin pharmacology. Ciprofloxacin is one of the most widely recognized fluoroquinolone antibiotics and has been on the market for decades. Because of its broad utility, it often comes up in practice, but it also carries significant adverse effect concerns and boxed warnings that pharmacists and prescribers need to k…

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Vilazodone Pharmacology 13:49

4M ago13:49

13:49

Vilazodone (brand name Viibryd) is an antidepressant with a unique pharmacologic profile compared to most other agents in the SSRI class. While not a first-line choice for every patient, understanding its mechanism, adverse effects, and interaction profile is essential for optimizing therapy and preventing downstream prescribing problems. Mechanism…

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Solifenacin Pharmacology 12:01

4M ago12:01

12:01

Solifenacin is a bladder antimuscarinic medication most commonly used for overactive bladder (OAB) with symptoms of urinary frequency, urgency, and urge incontinence. Like other agents in its class, understanding the pharmacology can help anticipate potential side effects, drug interactions, and downstream prescribing problems. Mechanism of Action …

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Itraconazole Pharmacology 10:50

5M ago10:50

10:50

In this episode, we break down itraconazole—a potent antifungal with a lot of baggage. If you’re a pharmacist, clinician, or student who needs to understand how this drug works and why it can be tricky to use, this episode is for you. We start with the basics. Itraconazole blocks 14α-demethylase, an enzyme fungi need to make their cell membranes. T…

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Levomilnacipran Pharmacology 16:47

5M ago16:47

16:47

In this episode of our pharmacology podcast, we take a deep dive into the pharmacology of levomilnacipran (Fetzima), a unique serotonin-norepinephrine reuptake inhibitor (SNRI) approved for the treatment of major depressive disorder (MDD) in adults. Designed for pharmacy students, clinicians, and anyone interested in psychopharmacology, this episod…

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Asenapine Pharmacology 16:10

5M ago16:10

16:10

Asenapine is an atypical antipsychotic that acts as an antagonist at multiple receptors, including dopamine D2 and serotonin 5-HT2A, contributing to its antipsychotic and mood-stabilizing effects. Adverse effects of asenapine include somnolence, dizziness, and extrapyramidal symptoms. Because asenapine is significantly metabolized by CYP1A2, inhibi…

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Loxapine Pharmacology 14:36

6M ago14:36

14:36

Loxapine is a first-generation (typical) antipsychotic with dopamine D2 receptor antagonism as its primary mechanism, though it also has affinity for serotonin 5-HT2A receptors, making its pharmacology somewhat atypical. Loxapine is available in multiple formulations, including oral capsules and an inhalation powder, the latter approved specificall…

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Friendly Fire! - Autoimmune Disease | The ATP Projectr 502 53:27

6M ago53:27

53:27

Join hosts Nick and Steve on The ATP Project as they dive into the complex world of autoimmunity, where the immune system mistakenly attacks the body. From rheumatoid arthritis to lupus and ankylosing spondylitis, learn about the triggers like genetics, infections, gut dysbiosis, and environmental toxins. Discover how diet, stress, and lifestyle im…

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Friendly Fire! - Autoimmune Disease | The ATP Projectr 502 53:27

6M ago53:27

53:27

Join hosts Nick and Steve on The ATP Project as they dive into the complex world of autoimmunity, where the immune system mistakenly attacks the body. From rheumatoid arthritis to lupus and ankylosing spondylitis, learn about the triggers like genetics, infections, gut dysbiosis, and environmental toxins. Discover how diet, stress, and lifestyle im…

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Ketoconazole Pharmacology 14:18

6M ago14:18

14:18

Ketoconazole is an imidazole antifungal that works by inhibiting fungal cytochrome P450 14α-demethylase, an enzyme essential for ergosterol synthesis, which disrupts fungal cell membrane integrity. Common adverse effects of ketoconazole include nausea, vomiting, abdominal pain, and elevated liver enzymes, with hepatotoxicity being a notable concern…

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NSAID Drug Interactions 16:28

6M ago16:28

16:28

NSAIDs can reduce the effectiveness of antihypertensive medications such as ACE inhibitors, ARBs, beta-blockers, and diuretics by promoting sodium and water retention and decreasing renal blood flow. Combining NSAIDs with anticoagulants or antiplatelet agents like warfarin or aspirin significantly increases the risk of gastrointestinal bleeding, du…

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Drivers of Insulin Resistance - More Than Just Diet! | The ATP Project 501 49:01

6M ago49:01

49:01

oin hosts Steve and Nick on The ATP Project as they dive into the surprising drivers of insulin resistance beyond diet. From chronic inflammation and stress to sleep disruption and medications, discover the hidden factors impacting your health and learn practical steps to improve insulin sensitivity. Tune in for science-backed insights and actionab…

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Drivers of Insulin Resistance - More Than Just Diet! | The ATP Project 501 49:01

6M ago49:01

49:01

oin hosts Steve and Nick on The ATP Project as they dive into the surprising drivers of insulin resistance beyond diet. From chronic inflammation and stress to sleep disruption and medications, discover the hidden factors impacting your health and learn practical steps to improve insulin sensitivity. Tune in for science-backed insights and actionab…

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Lotrisone (Clotrimazole/Betamethasone) Pharmacology 13:43

6M ago13:43

13:43

Lotrisone is a topical cream that contains a combination of clotrimazole, an antifungal, and betamethasone dipropionate, a corticosteroid. It is used to treat fungal skin infections such as athlete’s foot, jock itch, and ringworm that also involve inflammation or itching. Clotrimazole works by disrupting the fungal cell membrane, while betamethason…

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Fluphenazine Pharmacology 14:28

6M ago14:28

14:28

Fluphenazine is a high-potency typical antipsychotic that primarily acts as a dopamine D2 receptor antagonist in the mesolimbic pathway, reducing positive symptoms of schizophrenia. Extrapyramidal symptoms (EPS), such as dystonia, akathisia, and parkinsonism, are common due to potent D2 blockade in the nigrostriatal pathway. Neuroleptic malignant s…

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Naturopaths Explain SIBO: Causes, Symptoms and Fixes | The ATP Project 499 43:27

7M ago43:27

43:27

Nic and Steve dive into the world of gut health in this episode, focusing on SIBO-Small Intestinal Bacterial Overgrowth. They break down what SIBO is, why it's becoming increasingly common, and how it differs from other gut issues. The conversation covers typical symptoms like bloating, brain fog, and digestive discomfort, as well as the underlying…

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Naturopaths Explain SIBO: Causes, Symptoms and Fixes | The ATP Project 499 43:27

6M ago43:27

43:27

Nic and Steve dive into the world of gut health in this episode, focusing on SIBO-Small Intestinal Bacterial Overgrowth. They break down what SIBO is, why it's becoming increasingly common, and how it differs from other gut issues. The conversation covers typical symptoms like bloating, brain fog, and digestive discomfort, as well as the underlying…

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Quinapril Pharmacology 14:08

7M ago14:08

14:08

On this podcast episode, I discuss quinapril pharmacology, adverse effects, drug interactions, pharmacokinetics, and much more. Quinapril is a prodrug that is converted in the liver to its active metabolite, quinaprilat, which inhibits ACE, leading to decreased formation of angiotensin II and reduced aldosterone secretion. Hyperkalemia can occur wi…

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Nifedipine Pharmacology 11:36

7M ago11:36

11:36

Nifedipine is a dihydropyridine calcium channel blocker that selectively inhibits L-type calcium channels in vascular smooth muscle, leading to vasodilation and reduced peripheral vascular resistance. The extended-release formulation of nifedipine provides more stable plasma concentrations and is preferred for chronic management of hypertension and…

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Top 5 Nutrition Myths Debunked | The ATP Project 500 47:16

7M ago47:16

47:16

Join Nick and Steve on the 500th! episode of The ATP Project as they dive into the top 10 nutrition myths that have been thoroughly debunked, some of which are still widely believed today. Whether you're a health nerd or just here for the laughs, you'll leave with your mind (and maybe your meal plan) blown. As always, this information is not design…

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Top 5 Nutrition Myths Debunked | The ATP Project 500 47:16

7M ago47:16

47:16

Join Nick and Steve on the 500th! episode of The ATP Project as they dive into the top 10 nutrition myths that have been thoroughly debunked, some of which are still widely believed today. Whether you're a health nerd or just here for the laughs, you'll leave with your mind (and maybe your meal plan) blown. As always, this information is not design…

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Clotrimazole Pharmacology 15:20

7M ago15:20

15:20

On this podcast episode, I discuss Clotrimazole pharmacology, adverse effects, indications, administration, and much more. Clotrimazole is an imidazole antifungal that exerts its pharmacological effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This inhibition compromises membrane integrity, leading …

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Irbesartan Pharmacology 13:55

7M ago13:55

13:55

Irbesartan is an angiotensin II receptor blocker (ARB) used primarily for the management of hypertension and diabetic nephropathy in type 2 diabetes. It selectively inhibits the binding of angiotensin II to the AT1 receptor found in vascular smooth muscle and the adrenal gland. This blockade results in vasodilation, reduced aldosterone secretion, d…

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Is Your Eyesight At Risk? Do This NOW! | The ATP Project 498 46:33

7M ago46:33

46:33

Join hosts Nick and Steve on The ATP Project as they dive into the fascinating world of eye health! In this episode, they explore the causes of eye diseases like age-related macular degeneration, glaucoma, and cataracts, and share practical tips to protect your vision. From the power of antioxidants like lutein, zeaxanthin, and bilberry to the surp…

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Is Your Eyesight At Risk? Do This NOW! | The ATP Project 498 46:33

8M ago46:33

46:33

Join hosts Nick and Steve on The ATP Project as they dive into the fascinating world of eye health! In this episode, they explore the causes of eye diseases like age-related macular degeneration, glaucoma, and cataracts, and share practical tips to protect your vision. From the power of antioxidants like lutein, zeaxanthin, and bilberry to the surp…

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Benzonatate Pharmacology Podcast 9:38

7M ago9:38

9:38

On this episode, I discuss benzonatate pharmacology, adverse reactions, and much more. Tessalon Pearls (benzonatate) are a non-narcotic antitussive commonly prescribed to relieve dry, non-productive coughs. Benzonatate acts by numbing stretch receptors in the respiratory tract, lungs, and pleura, which helps suppress the cough reflex at its source.…

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Polyethylene Glycol (Miralax) Pharmacology 14:22

8M ago14:22

14:22

On this episode of the Real Life Pharmacology podcast, I discuss Miralax (polyethylene glycol) pharmacology, adverse effects, and much more. MiraLAX is an osmotic laxative commonly used to treat occasional constipation by retaining water in the stool to increase stool frequency and soften consistency. The standard adult dose of MiraLAX is 17 grams …