Best Transcriptomics Podcasts (2025)

Learn how to perform a powerful new tissue-clearing method, designed for whole-brain 3D spatial RNA imaging at single cell resolution, and able to provide uniform staining while enhancing tissue transparency in whole organs across multiple species. In this webinar, you will learn: • A groundbreaking tissue-clearing technique for precise whole-brain…

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Defining Lineage in Ambiguous Leukemia: A Transcriptomic View Ep 3.7 35:42

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11d ago35:42

35:42

Dr. Anikó Sijs-Szabó & Roger Mulet Lázaro, PhD, join Dr. Charles de Bock to unpack the challenges of diagnosing and treating acute leukemias of ambiguous lineage (ALAL). Discover how RNA sequencing, machine learning, and collaboration are shaping the future of precision medicine in hematology. 🎧 Listen and then read the full open-access article on …

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Advancing Blood Disorder Treatments Through Precision Therapeutics 15:08

3d ago15:08

15:08

In this week's episode, Blood editor Dr. Laura Michaelis interviews authors Drs. Terri Parker and Peter Lenting on their latest papers published in Blood Journal. Dr. Lenting discusses his work on introducing a new therapeutic approach to von Willebrand disease with the development of a novel bispecific antibody (KB-V13A12) that links endogenous mo…

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JHVS: Explantation of a Migrated Self-Expandable Aortic Valve Causing Type A Aortic Dissection: A Case Report 2:24

8h ago2:24

2:24

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251357570

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JHVS: Rethinking Surgical Timing in Aortic Regurgitation: A Case for Earlier Intervention 2:11

8h ago2:11

2:11

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251344848

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JHVS: Multiple and Mixed Valvular Heart Disease: State-of-the-Art 4:07

8h ago4:07

4:07

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251330128

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JHVS: Cardiac Damage Staging in Valvular Heart Disease 2:52

8h ago2:52

2:52

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251370475

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JHVS: Transforming Cardiac Care for Aortic Valve Disease Patients Undergoing TAVR: The Impact of Personalized Simulations and AI-Based Methods in Clinical Practice 3:35

8h ago3:35

3:35

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251336314

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JHVS: Data Resource Profile: The Heart Valve Society (HVS) Mitral and Tricuspid Valve Database 3:23

15h ago3:23

3:23

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241313425

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JHVS: Clinical and Hemodynamic Implications of Mitral Annular Calcification 3:02

8h ago3:02

3:02

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251347539

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JHVS: Mitral Valve Remodeling in Response to Atrial and Ventricular Changes: Mechanisms and Clinical Implications for Functional Mitral Regurgitation 3:05

8h ago3:05

3:05

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251344846

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JHVS: Antithrombotic Therapy in Infective Endocarditis: A Retrospective Analysis of Mortality and Complications 3:49

8h ago3:49

3:49

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251336319

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JHVS: Comparison of Different Osteogenic Media to Induce Aortic Valve Calcification in Vitro 2:54

8h ago2:54

2:54

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251344842

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JHVS: Volume 2, Issue 2 10:26

8h ago10:26

10:26

Read the issue here: https://journals.sagepub.com/toc/hvsa/2/2

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New Research: Mitochondrial DNA in TRALI and Venetoclax-Obinituzumab in CLL Trials 18:36

10d ago18:36

18:36

In this week's episode, associate editor Dr. James Griffin interviews researchers Dr. John Semple and Dr. Othman Al-Sawaf on their groundbreaking studies on transfusion-related acute lung injury and chronic lymphocytic leukemia treatment. Dr. Semple explored how mitochondrial DNA could act as a first hit in lung injury, while Dr. Al-Sawaf revealed …

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Bispecific Antibodies in Aggressive B-Cell Lymphoma: Real-World Insights and Future Directions 9:36

17d ago9:36

9:36

In this week's episode, Blood editor Dr. Laura Michaelis interviews author Dr. Taylor Brooks on his latest paper published in volume 146 issue 18 of Blood Journal. The conversation discusses outcomes of bispecific antibodies (epcoritamab or glofitamab) in treating aggressive B-cell lymphoma in a study with 245 patients. Findings show a tentative wa…

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What Factors Affect Safe Bedside Extubation After Mandibular Distraction? 19:03

2d ago19:03

19:03

In this episode of the Cleft Palate Craniofacial Journal podcast series, Pat Chibbaro, Multimedia Specialist, interviews Dr. Cory Resnick, author of the CPCJ article entitled, "What Factors Affect Safe Bedside Extubation After Mandibular Distraction?" (coauthored by Andrew J. Deek, Ryan Caprio, Snigdha Jindal, Faye Evans, and Raymond Park).…

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CPC 2025 Podcast: Genetic Testing in Craniofacial Care: Development of Algorithms for Testing Patients with Orofacial Clefting, Branchial Arch Anomalies, and Craniosynostosis 24:09

18d ago24:09

24:09

In this episode of the Cleft Palate Craniofacial Journal podcast series, Pat Chibbaro, Multimedia Specialist, interviews Maria Mills, author of the CPCJ article entitled, "Genetic Testing in Craniofacial Care: Development of Algorithms for Testing Patients with Orofacial Clefting, Branchial Arch Anomalies, and Craniosynostosis" (coauthored by Emily…

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Review Series on Follicular Lymphoma 17:38

7d ago17:38

17:38

In this Review Series episode, Associate Editor Dr. Philippe Armand speaks with multiple authors about what it might look like to improve treatments follicular lymphoma, a disease that has been put on the backburner of innovation due to its generally treatable nature. Dr. Armand discusses "Treatment of relapsed and refractory follicular lymphoma: w…

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Radiotherapy induced neurocognitive decline 16:05

25d ago16:05

16:05

Description: Dr. Iyad Alnahhas interviews Dr. Charlotte Sleurs about her and her team's recent manuscript entitled: "Radiotherapy-induced neurocognitive decline among adult intracranial tumor patients: A voxel-based approach", published online in Neuro-Oncology in May 2025.By Drs. Iyad Alnahha and Charlotte Sleurs

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FACE: Current Patterns in the Scope of Craniofacial Fellowship Training 18:48

27d ago18:48

18:48

This week, podcast hosts Hannes Prescher and Edy Ndem are joined by primary authors Kristine Carbullido and Daniel Cho as we explore the current scope of craniofacial training and how it translates to current surgeon practices Read the article here.

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Breakthroughs in Multiple Myeloma Treatment and Von Willebrand Disease Mechanisms 24:11

1M ago24:11

24:11

In this week's episode of the Blood Podcast, Associate Editor Dr. James Griffin interviews Drs. Binod Dhakal and Ruben Bierings about their respective papers published in this week's issue of Blood. Dr. Dhakal presents his study on using talquetamab, a bispecific antibody, as a bridging therapy before BCMA-targeted CAR T-cell therapy in multiple my…

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Spotlight on Acute Myeloid Leukemia 21:39

21d ago21:39

21:39

In this Spotlight series episode on Acute Myeloid Leukemia, Blood Editor, Dr. Selina Luger interviews Drs. Laura Michaelis and Alexander Perl on their paper in the series titled “The fit older adult with acute myeloid leukemia: clinical challenges to providing evidence-based frontline treatment”. The conversation explores challenges in treating AML…

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Busulfan-melphalan conditioning in newly diagnosed, transplant-eligible multiple myeloma; and use of spatial transcriptomics to probe the three-dimensional properties of multiple myeloma bone marrow microenvironments ... 13:13

1M ago13:13

13:13

In this week's episode we’ll learn more about a study comparing busulfan-melphalan with melphalan alone as the conditioning protocol for newly diagnosed, transplant-eligible multiple myeloma; then we will discuss data on how three-dimensional transcriptomics can reveal complex interactions between plasma cells and bone marrow microenvironments. Fea…

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Detecting Rare T-Cell Responses at Scale with ELISpot and FluoroSpot 1:04:09

1M ago1:04:09

1:04:09

Detecting rare antigen-specific T-cell responses requires assays that are both sensitive and scalable. Traditional methods like flow cytometry often struggle with high-throughput needs or with preserving precious sample material. In this episode of Listen In, you’ll discover how ELISpot and FluoroSpot assays overcome these challenges. These cell-ba…

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How I Treat Wiskott-Alrich syndrome 13:16

1M ago13:16

13:16

In this How I Treat podcast episode, Laura Michaelis, MD interviews Sung-Yun Pai, MD about their recently published article in Blood journal "How I treat Wiskott-Alrich syndrome". They highlight recent updates in treatment, including new risk-benefit calculations due to safer treatments and longer follow-ups. Challenges include late diagnosis, lack…

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Use of Marstacimab for Prophylaxis in hemophilia A and B; matched-donor allogeneic CD19 CAR-T in adult B-ALL; a new prognostic index for T-cell cutaneous lymphomas 19:43

2M ago19:43

19:43

In this week's episode we'll learn about targeting the tissue factor pathway inhibitor with a monoclonal antibody to rebalance HEMOSTASIS in hemophilia A and B. In the phase 3 BASIS trial, the monoclonal antibody marstacimab reduced bleeding events, and was generally well tolerated, with no unanticipated side effects. After that: matched-donor allo…

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EHA/EBMT Survey on Grading and Management of ICAHT - Ep 3.7 40:58

2M ago40:58

40:58

Join our host HemaSphere Scientific Editor Dr Charles de Bock as he chats with Dr Kai Rejeski, first author of this 2025 HemaSphere Top Cited –Clinical Award-winning paper. The conversation delves into the complexities of CAR-T therapy, particularly focusing on the associated toxicities and the need for a structured grading system. EHA/EBMT Survey …

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QOL and cognitive functioning in patients with oligodendroglioma 18:22

1M ago18:22

18:22

Dr. Iyad Alnahhas interviews Drs. Florien Boele and Martin Klein about their recent manuscript entitled: "Health-related quality of life and cognitive functioning in survivors of oligodendroglioma: An international cross-sectional investigation", published online in Neuro-Oncology in July 2025.By Drs. Iyad Alnahhas, Florien Boele, Martin Klein

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Epstein-Barr virus genomic variants in human disease states, somatic GATA1 mutations and leukemia in Down syndrome, and new definitions for high-risk multiple myeloma 18:01

2M ago18:01

18:01

In this week's episode, we’ll learn more about relationships between Epstein-Barr virus genomic variants and human diseases, including hematological malignancies; the presence and timing of somatic GATA1 mutations and their relationship to a Down syndrome-specific form of leukemia; and new definitions for high-risk multiple myeloma that emphasize t…

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Review Series on Acute Lymphoblastic Leukemia (ALL) 12:38

2M ago12:38

12:38

In this Review Series episode, Associate Editor Dr. Hervé Dombret speaks with Dr. Mark Litzow about the latest immunotherapy advances for Acute Lymphoblastic Leukemia (ALL). The discussion highlights innovative treatments like blinatumomab and inotuzumab, which are showing remarkable success in clinical trials, including an 85% three-year survival …

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Azacitidine holds promise in VEXAS syndrome; a step forward in precision blood matching; identifying a new vulnerability in TP53-mutated AML 18:58

2M ago18:58

18:58

In this week's episode we'll learn about Azacitidine in VEXAS syndrome. Treatment can provide responses in patients with this complex autoinflammatory disorder. But relapse rates were high, so long-term therapy may be required to maintain disease control. After that: A step forward in precision blood matching. High-throughput array genotyping enabl…

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Post-operative radiation in recurrent grade 1 meningiomas 19:39

2M ago19:39

19:39

Dr. Iyad Alnahhas interviews Drs. Felix Sahm and Maximilian Deng about their recent manuscript entitled: "Postoperative radiotherapy in subtotally-resected recurrent WHO grade 1 meningiomas with intermediate/ high-risk molecular profiles", published online in Neuro-Oncology in May 2025.By Drs. Felix Sahm, Maximilian Deng, Iyad Alnahhas

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FACE: Orbital Hypertelorism - A Systematic Review 21:37

2M ago21:37

21:37

Primary authors Russell Reid and Kanad Ghosh discuss orbital hypertelorism, including operative techniques for management, outcomes, and complications seen with treatment of this rare condition, with expert discussion facilitated by Sanjay Naran. Hosted by Hannes Prescher and FACE fellow editor Idorenyin "Edy" Ndem Read the article here.…

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Diffuse large B-cell lymphoma’s long-term effects on immune profiles, plasminogen activation and prevention of venous thromboembolism, and PARP inhibitors in hematological malignancies carrying epigenetic ... 18:31

2M ago18:31

18:31

In this week's episode we'll learn about persistent changes in immune profiles in patients who have had diffuse large B-cell lymphoma, or DLBCL, and other cancers; that plasminogen activation and plasmin activity do not appear to play a role in routine physiological prevention of venous thromboembolism, or VTE; and about a novel mechanism that make…

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“Ironing out” Tet2-mutant HSPCs; A CAR-T “license to kill” in T cell leukemia/lymphoma; insights on cHL genetics, through the lens of ctDNA 20:43

3M ago20:43

20:43

In this week's episode, we'll learn about how TET2 is often mutated in myeloid malignancies and clonal hematopoiesis. In new work, expansion of Tet2-mutant HSPCs was dependent on Ncoa4, the cargo receptor mediating ferritinophagy. We’ll iron out the implications. After that: a double-oh-seven license to kill in T-cell leukemia/lymphoma. WU-CART-007…

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Tackling NUP98 Rearranged AML in Pediatric Oncology - Ep 3.5 41:07

3M ago41:07

41:07

Host Dr Charles de Bock speaks with Prof Michel Zwaan and Prof Olaf Heidenreich, co-authors from the 2025 HemaSphere Award - Top Cited: Biology paper, "The MLL-Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML." The conversation delves into the complexities of #AML, particularly focusing on NUP98 rearranged AML and the therap…

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mRNA CAR T against GD2 in high-grade glioma models 29:43

3M ago29:43

29:43

Dr. Maya Graham interviews Dr. Jessica Foster about her and her team's recent manuscript, entitled "Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high-grade glioma models". This work was published online in Neuro-Oncology in May 2025.By Drs Maya Graham, Jessica Foster, Iyad Alnahhas

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Patient-Reported Outcomes of Primary Cleft Rhinoplasty: A Long-Term Assessment Using CLEFT-Q 27:31

3M ago27:31

27:31

In this episode of The Cleft Palate Craniofacial Journal podcast series, Pat Chibbaro, Multimedia Specialist, interviews Isabel A. Ryan and Jordan W. Swanson, authors of the CPCJ article entitled, "Patient-Reported Outcomes of Primary Cleft Rhinoplasty: A Long-Term Assessment Using CLEFT-Q" (coauthored by Jinggang J. Ng, Jusung Kim, Philip D. Tolle…

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Targeting NPM1 in AML with a menin inhibitor; in primates, a CD137 ADC eliminates acute GVHD 15:10

3M ago15:10

15:10

In this week's episode we'll learn about targeting NPM1 in acute myeloid leukemia. Researchers report the first clinical evidence of a menin inhibitor inducing complete remissions in AML with a NPM1 mutation. This validates NPM1 as a new therapeutic target in AML, alongside FLT3, IDH1/2, and KMT2A. Also on the podcast: targeting CD137 to prevent gr…

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How I Treat Series on Iron Overload in Hematologic Disorders 34:17

2M ago34:17

34:17

Blood Editor, Dr. Thomas Coates interviews Dr. Emanuele Angelucci on his paper, "How I manage iron overload in the hematopoietic cell transplantation setting" which is featured in Blood's "How I Treat Series on Iron Overload in Hematologic Disorders". See the full How I Treat series in volume 145 issue 4 of Blood.…

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Early prediction of follicular lymphoma patients with poor survival; immune hotspots in aplastic anemia; role of allo-transplant for Hodgkin lymphoma in the checkpoint inhibitor era 19:49

3M ago19:49

19:49

In this week's episode we'll learn about how by combining PET response with circulating tumor DNA, or ctDNA, in newly treated patients with follicular lymphoma, investigators identify those patients likely to progress within 24 months of initial treatment, also known as POD24. After that: Immune hotspots in aplastic anemia. These newly identified h…

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Exogenous CD19 stimulation in B-cell acute lymphoblastic leukemia treated with CD19 CAR T-cell therapy, sequential rapid immune-assay in heparin-induced thrombocytopenia diagnosis, and new survival prediction ... 18:42

3M ago18:42

18:42

In this week's episode, we’ll learn more about how exogenous CD19 stimulation affects CAR T-cell persistence in B-cell acute lymphoblastic leukemia treated with CD19 CAR T-cell therapy; new algorithms that incorporate sequential rapid immune-assays, intended to improve diagnosis of heparin-induced thrombocytopenia, and resource-adaptive survival pr…