In February 2016, a hit-team of 6 men burst through the doors of a boxing weigh-in at Dublin's Regency Hotel. There, a Kinahan Cartel lieutenant named David Byrne, was shot point blank in the head. The attack took place in front of a room packed full of sportspeople, media and civilians including young children. From that moment on, Irish gangland would never be the same again. The Kinahan's is a new true crime series from The Irish Sun telling the complete story of Ireland's most feared cri ...
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The Regency Trial Podcasts
Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.
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FF 84 ACHIEVE: Spironolactone flops in dialysis
1:29:05
1:29:05
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1:29:05The Filtrate Joel Topf @kidneyboy.bsky.social Swapnil [email protected] AC @medpeedskidneys.bsky.social Special Guest Mike Walsh Associate Professor in the Departments of Medicine and Health Research Methods, Evidence, and Impact, McMaster University as well as a Scientist at the Population Health Research Institute and a nephrologi…
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FF 83 CONFIDENCE: Can We Start Flozins and Finerenone Simultaneously?
1:29:10
1:29:10
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1:29:10The Filtrate Joel Topf @kidneyboy.bsky.social Swapnil Hiremath @hswapnil.medsky.social Nayan Arora captainchloride.bsky.social Sopia Ambruso @sophia-kidney.bsky.social Special Guests Brendon Neuen @brendonneuen.bsky.social Associate Professor and Program Lead, Renal and Metabolic at The George Institute for Global Health. Nephrologist and Director …
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On Remembrance Sunday in November 1987, an IRA bomb exploded in the Northern Irish town of Enniskillen - killing 11 people. No one has ever been charged. The Times’s Mario Ledwith returns to his hometown, asking who carried out these bloody murders, how the authorities failed to properly investigate, and why a silence continues to surround what hap…
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FF 82 DDAVP up the nose to prevent biopsy bleeding
59:49
59:49
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59:49The Filtrate Joel Topf Bluesky: @kidneyboy.bsky.social AC @medpeedskidneys.bsky.social Nayan Arora @captainchloride.bsky.social Special Guest Vandana Niyyar Professor of Medicine at Emory School of Medicine Editing by Nayan Arora The Kidney Connection written and performed by by Tim Yau Show Notes American Society of Diagnostic and Interventional N…
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FF 81 Metformin Termination as explored by Target Trial Emulation
1:19:43
1:19:43
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1:19:43The Filtrate Joel Topf Bluesky: @kidneyboy.bsky.social Jordy Cohen Bluesky: @jordybc.bsky.social Swapnil Hiremath Bluesky: @hswapnil.medsky.social Special Guest Edouard “call me Ed” Fu Assistant Professor and Medical Student, and second author of his second paper covered on NephJC. LinkedIn | Leiden University Medical Center Editing by Simon Topf a…
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Introducing: New Entertainment Podcast – Fields of Dreams
1:57
1:57
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1:57In 1970s Ireland, the nation's youth were craving an escape - and music was going to provide it. Over the course of the next few decades, what had been a gigging backwater was transformed into the centre of the live entertainment universe. Fields of Dreams tells the story of that remarkable change through the trailblazers who made it happen. Narrat…
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When an innocent postman was shot in the head in Dublin in October 2008, it barely registered on that day's national news. Dad-of-two Robert Delany was shot because he broke up a pub fight involving the wrong man. He survived the hit on his life, which took place at his home in front of his young daughter, carried out on the orders of a ruthless an…
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The Filtrate Joel Topf AC Gomez Sophia Ambruso Nayan Arora Special Guest Charles Edelstein, MD, PhD Professor, Medicine-Renal Med Diseases/Hypertension Extra-Special Guest Michelle Rheault, MD Professor of Pediatrics, University of Minnesota Editing by Simon and Joel Topf The Kidney Connection written and performed by by Tim Yau Show Notes KDIGO AD…
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FF 79 REGENCY, Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis
1:42:51
1:42:51
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1:42:51The Filtered Fragments (OG Filtrate) Joel Topf Jennie Lin Swapnil Hiremath Special Guest Brad Rovin GN God and second author from The Ohio State Koyal Jain GN Specialist from UNC Alfred Kim Rheumatologist from Washington University Editing by Simon Topf and Nayan Arora The Kidney Connection written and performed by by Tim Yau Show Notes Joel’s mono…
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FF 78 NephMadness, the dialysis region
1:08:59
1:08:59
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1:08:59The Filtrate Joel Topf Jordy Cohen Nayan Arora Special Guest Katie Kwon @katiekwonmd.bsky.social Mariana Murea @MarianaMurea Editing by Simon Topf and Joel Topf Show Notes NephMadness at AJKDblog.org The Hemodialysis Region Vote for your favoritesBy Freely Filtered
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The Filtrate Joel Topf Swapnil Hiremath AC Gomez Sopia Ambruso Nayan Arora Special Guests Michelle Rheault, Director, Division of Pediatric Nephrology, Professor of Medicine Tiffany Caza, Nephropathologist, Scientist and self-described Freely Filtered fan girl Editing by Simon Topf and Sophia Ambruso Show Notes 10. Healthcare Cyberattacks 9. ApoE i…
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The Filtrate Joel Topf Swapnil Hiremath AC Gomez Jordy Cohen Nayan Arora Special Guest Brendon Nuen Editing by Simon Topf and Nayan Arora Show Notes FINEARTS-HF in NEJM FINEARTS Kidney outcomes in JACC FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes in Nature Medicine discussion in NephJC BARACH-D: Low-dose spironolacton…
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Episode 70b Do Over: Predicting Preeclampsia, the PRAECIS trial
34:50
34:50
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34:50The Filtrate: Joel Topf Swapnil Hiremath With Special Guest: Michelle Hladunewich, Nephrologist at the University of Toronto Mir Melamed, Maternal-Fetal Medicine at the University of Toronto Editor Simon Topf Show Notes Priscilla Smith’s letter: Dear Joel and the Freely Filtered team, I am a long-time fan of your podcast and was looking forward to …
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We had a great NephJC get together. We recorded the whole event and packaged it into a podcast. Musical entertainment Tim Yau (@Maximal_Change) Too Sweet by Hozier Fairy Tale of New York by written Jem Finer and Shane MacGowan. Hear it performed by the Pogues. Interview of Tom Mueller Tom Mueller author of How to Make a Killing Jade Teakall@jmteake…
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The Filtrate: Jennie Lin Joel Topf Josh Waitzman Swapnil Hiremath With Special Guests Pedro Teixeira Jay Koyner Editor Sophia Ambruso Show Notes The article: A Randomized Trial of Intravenous Amino Acids for Kidney Protection NephJC Summary KDIGO Clinical Practice Guideline for Acute Kidney Injury (PDF) Steve Coca study Evaluation of Short-Term Cha…
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Episode 73: The KDIGO CKD 2024 Guideline Draft
1:32:16
1:32:16
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1:32:16The draft order: Sophia Ambruso Nayan Arora Swapnil Hiremath AC Gomez Joel Topf Editor Nayan Arora Show Notes Previous drafts: 2021 KDIGO Hypertension —Joel, Sophia, Swap, Nayan, Josh 2021 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan, Jennie 2022 The ISPD Peritonitis Guideline— Joel, Sophia, Swap, Nayan 2022 ASN Kidney Week Draft—Joel, Sophia, S…
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Description: Inside the global cocaine industry, where profits are counted up in millions and losses measured out in murders. Damien Lane introduces a new podcast series from The Times, Sunday Times and NewsCorp Australia, revealing how the drug business works like any multi-billion dollar corporation. To listen to the full series of Cocaine Inc. j…
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Episode 72: Nefecon for IgAN, The NefIgArd part B trial
1:32:16
1:32:16
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1:32:16The Filtrate: Joel Topf Josh Waitzman With Special Guest: Brad Rovin (@BradRovin) Chief of nephrology at The Ohio State University Wexner Medical Center, one of the authors of the Nefigard trial. Koyal Jain (@koyaljainMD) Program director of the GN Fellowship at University of North Carolina Roger Rodby (@NephRodby) Associate program director of the…
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The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Nayan Arora Sophia Ambruso With Special Guest: Brendon Neuen Super smart guy and clinical trialist Vlado Perkovic Lead author of FLOW and friend of NephJC Editor Joel Topf Show Notes The manuscript (NEJM): Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes The acr…
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Episode 70: Predicting Preeclampsia, the PRAECIS trial
1:16:20
1:16:20
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1:16:20The Filtrate: Joel Topf Swapnil Hiremath AC Gomez Nayan Arora With Special Guest: Anuja Java, complement god and pre-eclampsia research (Twitter) Shannon M. Clark, MD, FACOG, an honest to god, true, maternal-fetal medicine specialist. (Website | Instagram) Editor Nayan Arora Show Notes CHIP Study from 2015 (NEJM | NephMadness 2015) CHAP study from …
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PRESENTING: THE STARDUST TRAGEDY- COMING APRIL 25TH 2024
1:59
1:59
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1:59This 8 part series tells the story from the very beginning up until the current day, with several individual stories of the young victims as they set off for the Valentine’s night disco in the Stardust nightclub in Artane in 1981. The podcast continues with a thorough investigation into the fatal fire, testimonies from survivors, firefighters and f…
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Episode 69:DUPLEX Sparsentan, it’s no Acthar Gel
1:41:55
1:41:55
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1:41:55The Filtrate: Joel Topf Swapnil Hiremath Priya Yenebere Nayan Arora With Special Guest: Brendon Neuen Super smart guy and clinical trialist Michelle Rheault Lead author of DUPLEX and friend of the pod Show Notes Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis NephJC Summary | PubMed | NEJM KDIGO FSGS Guidelines 2021 (PDF) Charact…
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Freely Filtered 68: Inpatient hypertension
1:28:08
1:28:08
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1:28:08The Filtrate: Joel Topf Swapnil Hiremath Jordy Cohen AC Gomez With Special Guest: Tim Anderson @TimAndersonMD Editor: Priya Yenebere Show Notes Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults NephJC Summary | PubMed | JAMA Internal Medicine The Jordy AC collab: An Interactive Ambulatory Nephrology Cur…
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Freely Filtered 67: NephMadness and Animal House
47:44
47:44
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47:44Animal House Region NephMadness description by Tiffany Truong Editorial by Kelly Hyndman @DrKeeksPhD They May Look Cute, But Are All Animals Sweet? The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso Josh Waitzman With Special Guest: Kelly Hyndman Editor: Sophia Ambruso Show Notes Animal House 2018 with Mark Zeidel, MD (AJKDblog) Animal House 2…
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Freely Filtered 66: NephJC Summer Book Club
1:15:09
1:15:09
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1:15:09How Medicine Works, and When It Doesn’t Amazon The Filtrate: Joel Topf Josh Waitzman Jennie Lin With Special Guest: Jade Teakell Perry Wilson Editor: Joel Topf Show Notes Understanding Medical Research: Your Facebook Friend is Wrong. Coursera Illusory truth effect (Wikipedia) Number needed to treat (Wikipedia) NNT at MedPage Today: NNT on NephJC De…
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The Filtrate: Joel Topf Nayan Aurora Sophia Ambruso With Special Guest: Michael Collins Editor: Nayan Aurora Show Notes: Twitter is now X (NYT) Michael Collins (the astronaut, not the real one) PlasmaLyte by Baxter NephJC BEST Fluids summary Early Goal Directed Therapy for Sepsis NEJM manuscript which changed practice patterns and welcomed in an er…
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Freely Filtered 064: Freely Filtered with The Curbsiders Live at Kidney Week!
1:32:08
1:32:08
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1:32:08The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso AC Gomez Josh Waitzman Jennie Lin Nayan Arora The Curbsiders Matt F. Watto (@DoctorWatto) Paul Nelson Williams, America’s primary care physician (@PaulNWilliamz) With Special Guest: JD Foster (@KidneyVet) Sayed Tabatabai (@TheRealDoctorT) Nephrologist in Austin and the author of These Vital Si…
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Freely Filtered 063: Late Breaking and High Impact Clinical Trial Simultaneous Release!
2:05:22
2:05:22
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2:05:22The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso AC Gomez With Special Guest: Amit Garg (@AmitXGarg) Nephrologist at Western University, London, and lead PI of the EnAKT LKD trial. Susan Q. McKenzie (LinkedIn) Co-Founder & Chair, Transplant Ambassador Program. President of the Kidney Patient and Donor Alliance of Canada. Editor: Joel Topf Sh…
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Freely Filtered 062: Inaxaplin for APOL1 Kidney Disease
1:31:17
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1:31:17By NephJC
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Freely Filtered 061: Bicarb in Transplant
1:18:11
1:18:11
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1:18:11Bicarbonate did not slow the loss of GFR in this well done Swiss, single-blind study of transplant patients. The Filtrate: Joel Topf Nayan Arora Swapnil Hiremath Pirya Yenebere With Special Guest: Nav Tangri nephrologist and epidemiology at the University of Manitoba Editor: Nayan Arora Show Notes: Arsenal FC The London study that kicked it all off…
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Freely Filtered 059: Furosemide v Torsemide
1:02:29
1:02:29
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1:02:29The Filtrate: Joel Topf Nayan Arora Sophia Ambruso With Special Guest: Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA. His Google Schoolar page is better than yours. And returning for her fourth time (why do we keep inviting her back?) Sadiya Khan @heartDocSadiya Assistant Professor of Medicine (Cardi…
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As The Kinahan’s structures and key members begin to fall in a post-sanctions world, we ask some questions on our series finale… Where on earth are Christy and his two sons? How long can they stay on the run? And what comes next for Irish gangland… The Kinahans is brought to you by The Irish Sun. This series was written and produced by UrbanMedia. …
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Freely Filtered 060: HCTZ v Kidney Stones, The NOSTONE trial
1:42:42
1:42:42
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1:42:42The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Nayan Arora Sophia Ambruso With Special Guest: Megan Prochaska Assistant professor of medicine at University of Chicago John Asplin Medical Director Consultant LithoLink (Twitter) Editor: Joel Topf Show Notes: The LithoLink website Stone Camp tweet Prevention of Repeated Episodes of Kidney Ston…
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The 52 day trial of Gerry “The Monk” Hutch begins in the Special Criminal Court, but not before a huge plot twist happens in the eleventh hour. Jonathan Dowdall turns state, and brings a new Hollywood dimension to the “trial of the century”, as the court hears the in’s and outs of the pair's bugged trip up North. The Kinahans is brought to you by T…
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A European Arrest Aarrant is issued for Gerry Hutch, but he manages to evade authorities completely. Is it possible he has someone working on the inside? Tyson Fury continues his comeback, and the cash keeps stacking up for Daniel and others around him. A Tweet in 2020 highlights his presence in the sport like never before, and brings some unwanted…
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As the feud begins to trickle out, The Kinahan's establish themselves as a global powerhouse from their new base in the Middle East. Connections are forged with other international drug lords, and a “Super Mafia” is formed. Back closer to home, Jonathan Dowdall's past catches up with him, as he tries to flee Ireland to escape prosecution. The Kinah…
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In the wake of The Regency, Gardai are on high alert around the city, as retaliation attacks begin to take place on a near weekly basis. With The Kinahans gone into hiding, their foot soldiers carry out a series of brutal murders on Hutch allies. An underfunded police force struggles to keep on top of the violence, as The Regency’s first arrests ta…
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Things escalate between the Hutch and Kinahan gangs after the murder of Gary Hutch. A Lanzarote hit attempt on The Monk sends things to a boiling point. Then the event that changed everything… A boxing weigh-in at The Regency Hotel in Dublin goes south when a hit team storms the building in search of Daniel Kinahan. The Kinahans is brought to you b…
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The Kinahan gang receive a lot of unwanted attention after the murder of Paddy Doyle on The Costa Del Sol. Spanish police close in on the gang, as wiretaps reveal the extent of The Cartels intricate money laundering systems. After a large sum of money goes missing, things between Gary Hutch and Daniel Kinahan begin to sour. The repercussions will b…
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If Daniel and Christopher Kinahan Jr had been born into a different family, their path in life would have certainly been different. Listen to how the pair got involved in organised crime from a young age, and how relationships forged in their late teens would have drastic consequences for the world of organised crime in the years to come. The Kinah…
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Episode 2: As Christy faces his first long stint behind bars, a chance encounter inside the halls of Mountjoy Prison forges a relationship that will change Irish gangland forever. Upon his release in the early 90’s, Christy makes a decision to leave Ireland for good. While in the UK, Holland and Belgium, we see how the Dapper Don hones his craft, a…
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Episode 1: The Kinahans begins its story in Dublin of the late 1970’s as heroin burst onto the scene. The Dunne’s, Ireland’s leading crime group, were responsible for much of the devastation the new opioid had brought across Dublin City. It wasn’t long before a young petty criminal from Phibsboro wanted a slice of the pie. His name was Christy Kina…
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In February 2016, a six person hit-team burst through the doors of a boxing weigh-in at Dublin's Regency Hotel. There, a Kinahan Cartel lieutenant named David Byrne was brutally murdered, as other senior members of the gang made a lucky escape. The attack took place in front of a room packed full of boxers, journalists, civilians, and young childre…
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Freely Filtered 057: NephMadness 2023 TMA
1:21:41
1:21:41
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1:21:41The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Sophia Ambruso With Special Guest: Anna Vinakova Associate Professor of Medicine at Virginia Commonwealth University. NephMadness Executive. Vanuja Java is a transplant nephrologist at Washington University in St. Louis, MO. Her research involves functional characterization of genetic variants …
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Welcome to the NephMadness PodCrawl The idea behind a podcrawl is for a variety of podcasts to coordinate on timing and topic to push a theme and get each other’s listeners to explore all of the podcasts. One of the first goals behind NephMadness was to build a community and in the early years of Twitter, NephMadness was central to the formation of…
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The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Sophia Ambruso With Special Guest: Amit Garg @AmitXGarg, Nephrologist at Western University, London, and lead PI of the MYTEMP trial. Editor: Joel Topf Show Notes: MyTEMP in pubmed: Personalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-rando…
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The Filtrate: Joel Topf Swapnil Hiremath Jordy Cohen With Special Guest: Laurie Tomlinson. @Roxytonin Nephrologist at University Hospitals Sussex and research hero of Jordy. Editor: Priya Yenebere Show Notes: STOP-ACE in pubmed: Renin-Angiotensin System Inhibition in Advanced Chronic Kidney Disease STOP-ACE Summary in NephJC Prior data showing pres…
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The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Sophia Ambruso Priya Yenebere With Special Guest: Brendon Neuen, Secretariat of the SGLT2 Trialists Consortium and cool guy on Twitter. Editor: Sophia Ambruso Show Notes: Joel’s Conflict of Interest Statement. Sophia is also conflicted with Astra Zeneca and Brendon with everybody in the SGLT2i …
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Freely Filtered 053: The Kidney Week Draft
1:04:34
1:04:34
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1:04:34The Filtrate: Joel Topf Swapnil Hiremath Nayan Arora Sophia Ambruso Editor: Nayan Arora Show Notes: Joel’s Conflict of Interest Statement The Draft Board EMPA-Kidney is “off the board” Lunch Symposium on Current and Future Approaches to the Diagnostic Assessment and Management of AKI in Patients with Cirrhosis provided by an educational grant from …
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Freely Filtered 052: Acetazolamide for Acute Decompensated Heart Failure (ADVOR)
1:09:56
1:09:56
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1:09:56The Filtrate: Joel Topf Jordy Cohen Nayan Arora Sophia Ambruso Special Guests: Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA returns for his second episode (SODIUM-HF). His Google Schoolar page is better than yours. David Ellison @dhekidney is professor of medicine at Oregon Health Science University…
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