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This podcast is about Intensive care pharmacology and physiology. This is created to prepare intensive care trainees for their primary CICM exams. However, it will be of benefit to anyone who works in intensive care and keen to acquire new knowledge or want to refresh their memory.
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Critical Care Education is a website created to share recent literature on practical topics in critical care. The philosophy behind this is “Learn to Share & Share to Learn”. The blogs are aimed to provoke thoughtful discussion in a Socratic manner. The blogs will cover various clinical, non-clinical topics and imaging from the critical care world. To know more, visit https://critcareedu.com.au or call 04 7856 0636
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Every fortnight Dr Syl interviews doctors from across Australia. They talk about their lives and careers, their highs and their lows, and their passions and frustrations. Dr Syl is a Junior Doctor from Sydney, Australia. Together, let's try and understand this incredible journey we call Medicine and Life. Check out highlight clips on Dr Syl's YouTube Channel: https://www.youtube.com/c/DrSyl
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# Epi 98 - ICU Primary Snippet 41 - Anatomy of Sympathetic Nervous System
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7:58
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In this episode, we discuss the anatomy of sympathetic nervous system w.r.t origin, fibre type, receptors and neurotransmitters.
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Epi 97 - ICU Primary Snippet 40 - Metoprolol Vs Verapamil
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6:16
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In this episode, we compare and contrast the pharmacological profiles of Metoprolol and verapamil.
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In this episode, we cover the production, metabolism and the role played by lactate in the body.
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Epi 95 - ICU Primary Snippet 38 - Work of Breathing and Lung Efficiency
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In this episode, we discuss the concept of Work of breathing and lung efficiency.
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Epi 94 - ICU Primary Snippet 37 - Femoral Vein anatomy
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5:55
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In this episode, we discuss the procedural anatomy of the femoral vein including surface
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#Epi 93 - ICU Primary Snippet 36 - Fibrinolysis and Alteplase
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5:54
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In this episode, we discuss the process of fibrinolysis in relation to coagulation cascade and the pharmacology of Alteplase.
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#Epi 92 - ICU Primary Snippet 35 - Remifentanyl Vs Fentanyl
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8:00
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In this episdoe, we compare and contrast fentanyl and remifentanyl.
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Paracetamol MoA: 1. COX inhibition preventing prostaglandin synthesis 2. Prevention of re-uptake of endocannabinoids 3. Enhancement of inhibitory serotonergic pathways Side Effects: Generally well tolerated. Hepatotoxicity in overdose, hypotension with IV administration NSAID's Non-Selective (i.e. Ibuprofen) MoA: Inhibition of COX 2 +/- COX 1 to de…
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#Epi 91 - ICU Primary Snippet 34 - Receptors - Agonist, Partial agonist and Inverse agonist
8:32
8:32
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in this episode, we discuss the role of various receptors and describe the terms - partial agonist, antagonist, and inverse agonists.
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#Epi 90 - ICU Primary Snippet 33 - Venous Admixture and effect of Supplemental Oxygen
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7:27
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In this episode, we discuss the concept of venous admixture and the effect of supplemental oxygen on it in adults.
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Epi 89 - ICU Primary Snippet 32 - Effect of sudden and sustained increase in afterload on LV.
7:33
7:33
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In this episode, we discuss the consequences of sudden and sustained afterload increase on the Left ventricle.
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#Epi 88 - ICU Primary Snippet 31 -Furosemide Vs Acetazolamide
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8:48
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In this episode, we discuss the differences between two diuretic medications - Furosemide and Acetazolamide.
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#Epi 87 - ICU Primary Snippet 30 - Opioid Receptors
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7:16
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In this episode, we discuss various opioid receptors, their characteristics, distribution and activation process.
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#Epi 86 - ICU Primary Snippet 29 - Renal Physiology - Urine concentrating mechanisms
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9:46
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In this episode, we discuss various mechanisms by which the kidney concentrates urine.
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#Epi 85 - ICU Primary Snippet 28 - Neonatal Physiology Cardiovascular Changes
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13:41
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In this episode, we discuss the CVS changes after the birth.
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#Epi 84 - ICU Primary Snippet 27 - Neonatal Physiology Part 1
9:56
9:56
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In this episode, Dr Mike Clifford talks about respiratory changes occurring at birth.
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#Epi 83 - ICU Primary Snippet 26 - Uteroplacental Circulation
10:25
10:25
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In this episode, we discuss the key characteristics of uteroplacental circulation, including double Bohr and double Haldane effect.
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# Epi 82 - ICU Primary Snippet 25 - CVS changes during Pregnancy and at Term.
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9:48
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In this episode, Mike and I discuss the physiological changes in the cardiovascular system during pregnancy and at the term, their implication on pharmacokinetics.
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#Epi 81 - ICU Primary Snippet 24 - Respiratory changes during Pregnancy and Term
10:16
10:16
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In this episode, Mike and I discuss the respiratory changes during the pregnancy and at the term.
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#Epi 80 - ICU Primary Snippet 23 - Control of Breathing
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12:55
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In this episode, we discuss the control of breathing and its clinical relevance.
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#Epi 79 - ICU Primary Snippet 22 - Arterial Pressure Transducers
8:33
8:33
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In this episode, Mike discusses arterial pressure transducers, including natural frequency, resonance and damping.
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#Epi 78 - ICU Primary Snippet 21 - CO2 carriage in Blood
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7:47
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In this podcast, we discuss CO2 carriage in blood.
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#Epi 77 - ICU Primary Snippet 20 - Structure of Adult Haemoglobin
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6:30
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In this episode, we discuss the structure and functions of adult haemoglobin.
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# Epi 76 - ICU Primary Snippet 19 - pK/pD changes at Term in Pregnancy
7:08
7:08
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In this episode, we discuss various pharmacokinetic and pharmacodynamic changes that take place at term during pregnancy.
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# Epi 75 - ICU Primary Snippet 18 - Factors affecting Cardiac Output
10:20
10:20
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In this snippet, we cover all the physiological factors affecting Cardiac output.
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# Epi 74 - ICU Primary Snippet 17 - Factors affecting Airway resistance
8:49
8:49
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In this episode, we discuss various physiological factors affecting airway resistance.
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