The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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State Violence Research Network Podcasts
Podcast by State Violence Research Network
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Catch up on the biggest stories of the day from Washington with interviews and analysis from leading journalists. Posted weekdays at 6:30 pm ET. From C-SPAN, the network that brings you the "Q&A" podcast.
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Welcome to the official podcast channel of the Social Interventions Research and Evaluation Network (SIREN) at the University of California, San Francisco.
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The Common Thread of All Technology: Monitoring the Situation, Ep.1
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1:00:02
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1:00:02Announcing our new show, Monitoring the Situation, hosted by a16z General Partners Erik Torenberg and Katherine Boyle, with guest Eddie Lazzarin, CTO of a16z crypto. In this first episode, we ask how American Dynamism, consumer, games, and crypto all fit together, from Palmer/Oculus to Marc Andreessen’s Techno-Optimist Manifesto, while also explori…
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Weekend Edition: Political Polarization in the U.S., Jimmy Kimmel & the FCC, and FDA's new approach on vaccine policy and autism research
31:28
31:28
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31:28In this weekend's episode, three segments from this past week's Washington Journal. First, a discussion with former Democratic Congressmen Tim Roemer – and Republican Congressman Charles Boustany from the non-profit group Issue One -- on efforts to reduce political polarization in the U.S. Then, Former FCC Chair Tom Wheeler discusses the Jimmy Kimm…
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Former FBI Dir James Comey indicted and other top stories this week
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56:52While Congress is out of session, and President Donald Trump spent the day in New York at the Ryder Cup golf tournament, Washington Today look at some of the major stories this past week, including: *Former FBI Director James Comey is indicted for lying to Congress. President Trump says it is justice and not revenge against a political opponent. *D…
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Congressional Democratic Leaders say they will not be intimated by threat of large-scale federal worker layoffs if government shuts down
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58:02White House prepares for widespread layoffs of federal workers at government agencies if there is a government shutdown starting October 1st, the new fiscal year. We will hear from the House Democratic leader Hakeem Jeffries, President Donald Trump, and talk with Reuters congressional reporter Bo Erickson (10); President Trump signs a deal tofacili…
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From Vibe Coding to Vibe Researching: OpenAI’s Mark Chen and Jakub Pachocki
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52:05
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52:05What comes after vibe coding? Maybe vibe researching. OpenAI’s Chief Scientist, Jakub Pachocki, and Chief Research Officer, Mark Chen, join a16z general partners Anjney Midha and Sarah Wang to go deep on GPT-5—how they fused fast replies with long-horizon reasoning, how they measure progress once benchmarks saturate, and why reinforcement learning …
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Sen. Cruz (R-TX) says "politically motivated violence is wrong" and "this must stop" after anti-ICE message found on ammunition near gunman in deadly shooting at ICE facility in Dallas
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53:39
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53:39A gunman kills two detainees at an U.S. Immigration and CustomsEnforcement facility in Dallas in what the FBI Director Kash Patel says lookslike a politically motivated attack. Sen. Ted Cruz (R-TX) says of this, andother recent attacks, "This violence is wrong and needs to stop"; ABClate night talk show host Jimmy Kimmel returns to the airwaves aft…
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Software finally eats services - Aaron Levie
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59:33
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59:33Should the US put a price on H-1B visas, or would that block the flow of new talent? Are AI coding agents actually making teams way more productive, or is it just hype? And in the AI platform shift, will the big winners be incumbents or new AI-native startups? Erik Torenberg is joined by Box co-founder and CEO Aaron Levie, a16z board partner Steven…
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Pres. Trump in UN speech rails against migration, clean energy, UN ineffectiveness; Pres. Trump cancels meeting on gov't funding with House & Senate Dem leaders to avoid shutdown
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50:42President Donald Trump speaks at the opening the 80th session of the United Nations on his “America First” agenda, criticizing the UN for being ineffective at preventing or stopping wars and Europe for his immigration policies; President also meets in New York City with Ukrainian President Volodymyr Zelensky and in a post said Ukraine should be abl…
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America's Autism Crisis and How AI Can Fix Science with NIH Director Jay Bhattacharya
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58:13
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58:13Dr. Jay Bhattacharya is one of the country’s top medical experts and a 24-year professor of medicine at Stanford. After being censored and deplatformed during COVID for his role in opposing harsh lockdowns, he was appointed Director of the National Institutes of Health by President Trump in 2025. a16z General Partners Erik Torenberg, Vineeta Agarwa…
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Pres. Trump & FDA link autism rise to acetaminophen use during pregnancy, and that drug Leucovorin is a potential treatment for autism
59:37
59:37
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59:37President Donald Trump joins federal health officials to announce that pain reliever acetaminophen, the active ingredient in Tylenol, used by pregnant women, is linked to rising cases of autism, and that the drug Leucovorin is a potential treatment for autism; Disney says late night host Jimmy Kimmel is returning to the air on ABC, less than a week…
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Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government vs. China
1:40:00
1:40:00
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1:40:00Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip race. To make sense of it all, Erik Torenberg is joined by Dylan Patel, chief analyst at SemiAnalysis, joins Sarah Wang, general partner at a1…
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Charlie Kirk and the Rise of Political Violence
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23:39
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23:39In this episode of Honestly with Bari Weiss, we share a special conversation featuring a16z general partner Katherine Boyle in the wake of Charlie Kirk’s shocking assassination. Katherine reflects on what courage means in a culture where words and debate are increasingly met with violence. Drawing on faith, history, and her own response to recent t…
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Weekend Edition: Americans View of the Economy, Constitution Day, and Trump Administration Approach to Vaccines
27:55
27:55
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27:55In this weekend's episode, three segments from this past week's Washington Journal. First, a conversation on how Americans are viewing the economy right now with Heather Long - Washington Post columnist and chief economist for Navy Federal Credit Union. Then, we speak with National Constitution Center President & CEO Jeffrey Rosen about the history…
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Senate fails to pass both Republicans & Democratic proposals to extend federal government funding, increasing chances of a shutdown starting October 1
58:37
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58:37Senate fails to pass two versions of a government funding extension to avoid a shutdown At the end of the month: a Republican one that the House passed today that funds the government for another 7 weeks, and a Democratic one that does that but also extends Obamacare insurance subsidies; House passes a resolution to honor the life and legacy of Cha…
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Pres. Trump & British Prime Minister Starmer talk tech investment, Ukraine & Gaza wars, and Kimmel suspension & free speech at joint news conference in England
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57:02President Donald Trump meets with British Prime Minister Keir Starmer on the final day of his state visit to Great Britain. The two announce what they call a "U.K.-U.S. Tech Prosperity Deal" and answer questions at a news conference about the wars in Ukraine & Gaza. We hear from the leaders and talk about the state visit with C-SPAN's Westminster C…
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Federal Reserve cuts interest rates quarter point; newest Fed Governor Stephen Miran votes no, calls for half-point cut
55:58
55:58
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55:58Federal Reserve announces an interest rate cut of a quarter percentage point, lowering borrowing costs for the first time since December. Newest Fed Governor Stephen Miran, who has taken a leave of absence from his job as chair of the White House Council of Economic Advisers, votes for a bigger cut of 0.5%; U.S. House begins work on the federal gov…
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The Death of Search: How Shopping Will Work In The Age of AI
45:22
45:22
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45:22The web is unhealthy, and AI agents are about to rewrite how we shop. In this episode, a16z General Partner Alex Rampell and Partner Justine Moore explore how AI agents will change commerce and the implications for Google’s business model, affiliate marketing, online shopping, and more. Timecodes: 0:00 Introduction 0:12 The Role of AI Agents in Com…
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FBI Director Kash Patel testifies on high-level FBI firings, releasing Epstein files, Charlie Kirk shooting investigation
59:54
59:54
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59:54FBI Director Kash Patel testifies before the Senate Judiciary Committee about accusations the agency is being politicized, whether all the Epstein files will be released and his handling of the investigation into the shooting death of conservative activist Charlie Kirk; Utah County's Attorney General says the suspect in the Kirk shooting is being c…
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OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software? In this episode, General Partner Anjney Midha goes behind the scenes with one of Codex’s product leads- Alexander Embiricos - to unpack its origin story, why its PR success ra…
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Pres. Trump deploys the National Guard to Memphis, Tennessee, calling it a ‘replica’ of his anti-crime effort in Washington, DC
38:08
38:08
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38:08President Donald Trump announces he’s sending the National Guard into Memphis, Tennessee to combat crime; Vice President JD Vance host the late Charlie Kirk's daily radio show; talks continue in Congress to keep the government open and funded past the end of the month. Learn more about your ad choices. Visit megaphone.fm/adchoices…
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Can we make science as fast as software? In this episode, Erik Torenberg talks with Patrick Hsu (cofounder of Arc Institute) and a16z general partner Jorge Conde about Arc’s “virtual cells” moonshot, which uses foundation models to simulate biology and guide experiments. They discuss why research is slow, what an AlphaFold-style moment for cell bio…
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Weekend Edition: Charlie Kirk, Remembering 9/11 and Dr. Paul Offit
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28:01
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28:01In this weekend's episode, three segments from this past week's Washington Journal. First – we chat with Punchbowl News congressional reporter Max Cohen about the prospects for a potential government shutdown in a few short weeks – and the political and policy obstacles to a potential deal. Then: Vaccine expert Dr. Paul Offit discusses his recent r…
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Gov. Spencer Cox (R-UT) says 'we got him' in announcing the arrest of a 22-year-old suspected of fatally shooting conservative activist Charlie Kirk
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53:25Gov. Spencer Cox (R-UT) announces the arrest in the shooting death of conservative activist Charlie Kirk of 22-year-old suspect Tyler Robinson of Utah; President Donald Trump says he will send National Guard to Memphis, Tennessee, the next city he is targeting with federal resources to reduce crime; former White House Press Secretary Karine Jean Pi…
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Ben Horowitz: Why Hesitation is a CEO’s Worst Enemy
1:35:38
1:35:38
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1:35:38In this conversation from Lenny’s Podcast, Ben Horowitz joins Lenny to discuss the psychological muscle every founder needs, why hesitation can be fatal for CEOs, when it’s time to replace a founder, and how to normalize failure while building confidence. They also explore the Databricks founding story, investing in Adam Neumann after WeWork, wheth…
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Manhunt continues for Charlie Kirk's killer; 9/11 terror attack anniversary; Senate GOP changes rules to speed up nominee confirmation
55:46
55:46
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55:46FBI releases photos of a person of interest in the shooting death of conservative political activist Charlie Kirk and asks the public for help in identifying him. FBI also gives an update on the evidence recovered sofar, including the suspected firearm used; President Donald Trump announces he will award Charlie Kirk a posthumous Presidential Medal…
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The $13T U.S. mortgage market serves 50M homeowners but still runs on decades-old software. In this episode, a16z GP Angela Strange hosts Tim Mayopoulos (ex-CEO of Fannie Mae and ex-president of Blend), Mike Yu (co-founder and CEO of Vesta), and Andrew Wang (co-founder and CEO of Valon) to unpack why standardization and regulation slow change, and …
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Conservative activist Charlie Kirk is shot & killed while speaking at university in Utah
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53:41
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53:41Conservative activist Charlie Kirk is shot and killed at an event at Utah Valley University; Senate Minority Leader Chuck Schumer (D-NY) forces a vote in the Senate on an amendment to release all the files related to the case of convicted sex offender Jeffrey Epstein; NATO Secretary General Mark Rutte says Russia flying drones over Poland "reckless…
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Chris Dixon on How to Build Networks, Movements, and AI-Native Products
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42:59
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42:59Why do some consumer products explode into networks that reshape the internet, while others fade away? Today on the podcast, a16z general partners Anish Acharya and Chris Dixon take on that question. Anish invests in AI-native consumer products and the next wave of consumer tech. Chris is best known for his work in Web3 and network economies, and h…
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MAHA Commission releases report on reducing chronic disease in children, with emphasize on nutrition & lifestyle changes over more gov't regulation
57:12
57:12
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57:12Trump Administration's Make America Health Again (MAHA) Commission releases a report with strategies to fight childhood chronic disease that focuses more on nutrition and lifestyle changes rather than government regulations; White House says President Donald Trump would be willing to bring in a handwriting expert to show that it is not his signatur…
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Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics
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1:01:04What happens when AI collides with salesmanship, streaming-era sports, and healthcare? In this episode, Erik Torenberg is joined by Mark Cuban, entrepreneur, Dallas Mavericks co-owner, and founder of Cost Plus Drugs. Topics include fiery group chats and how dissent sharpens thinking, the sales playbook of modern politics, and concrete fixes for U.S…
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Supreme Court lifts restrictions on LA immigration stops set after agents swept up US citizens
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36:32News from the Supreme Court today….In a 6-3 decision, it blocked a federal judge’s ruling that restricted federal officers’ ability to conduct immigration stops in the Los Angeles area…. The Court also received… a formal request from the White House to let it hold back 4 billion dollars of congressionally approved foreign aid. The appeal comes afte…
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Who’s speaking up for startups in Washington, D.C.? In this episode, Matt Perault (Head of AI Policy, a16z) and Collin McCune (Head of Government Affairs, a16z) unpack the “Little Tech Agenda” for AI- why AI rules should regulate harmful use, not model development; how to keep open source open; the roles of the federal government vs states in regul…
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Building APIs for Developers and AI Agents
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26:34
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26:34Stainless founder Alex Rattray joins a16z partner Jennifer Li to talk about the future of APIs, SDKs, and the rise of MCP (Model Context Protocol). Drawing on his experience at Stripe—where he helped redesign API docs and built code-generation systems—Alex explains why the SDK is the API for most developers, and why high-quality, idiomatic librarie…
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Weekend Edition: Epstein Files and the 2026 Midterm Elections
19:21
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19:21In this weekend's episode, three segments from this past week's Washington Journal. Congress returned to Washington this week – and immediately was consumed by the Epstein files controversy and the looming government funding deadline at the end of the month. We talk with two lawmakers – on opposites sides of the aisle -- about potential Congression…
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Labor Dept says U.S. added 22K jobs in August, lower than expected; Pres. Trump renames Dept of Defense to Dept of War
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49:15
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49:15Labor Department says the U.S. added just 22,000 jobs in August, lower than expectations, and the unemployment rate goes up to 4.3%. President Donald Trump says the real jobs numbers will be next year, after his policies have a chance to take effect; Sen. Elissa Slotkin (D-MI) talks about her vision of keeping the needs of the U.S. middle class fro…
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How to Be Free: Shaka Senghor, Oprah Winfrey, Ben Horowitz
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36:33
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36:33Taken from The Oprah Podcast, this special episode brings together Shaka Senghor, a16z cofounder Ben Horowitz, and Oprah Winfrey for a powerful conversation on resilience and transformation. Shaka, a resilience expert, motivational speaker, and bestselling author of Writing My Wrongs, shares his journey from incarceration to redemption along with i…
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Health Secretary Robert F. Kennedy, Jr. at a Senate hearing defends vaccine policy changes and firing top CDC officials
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58:57Health & Human Services Secretary Robert F. Kennedy, Jr. defends his vaccine policy changes and firing of top officials at the Centers for Disease Control & Prevention, before the Senate Finance Committee. Almost all the committee's Democrats are calling on him to resign. Secretary Kennedy is also asked about studies on the causes of autism, and ab…
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Is non-consensus investing overrated—or the secret to venture returns? a16z General Partner Erik Torenberg is joined by Martín Casado (General Partner, a16z) and Leo Polovets (General Partner, Humba Ventures) to unpack the debate that lit up venture Twitter/X: should founders and VCs chase consensus, or run from it? They explore what “consensus” re…
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Survivors of sexual abuse by Jeffrey Epstein tell their emotional stories, call for release of more Justice Dept files; Pres. Trump again calls it a 'Democrat hoax'
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58:08
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58:08Survivors of sexual abuse by the late Jeffrey Epstein tell their emotional, personal stories in a news conference on Capitol Hill with Members of Congress of both parties who have been calling for the release of all the Justice Department files in the investigation of Epstein; President Donald Trump again calling that effort on the Epstein files a …
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Jack Altman & Martin Casado on the Future of VC
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53:28Jack Altman sits down with Martin Casado, General Partner at a16z, to unpack the shifting dynamics of venture capital and why media matters more than ever. They cover a16z’s evolution from generalists to specialized platforms, the rise of AI infrastructure, and why today’s fiercest battles are often for talent, not market share. Timecodes: 0:00 Int…
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President Trump says about sending National Guard to Chicago 'we're going in' and 'I didn't say when'
57:32
57:32
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57:32President Donald Trump says, "we're going in" and "I didn't say when",when asked if he plans to send the National Guard to Chicago to combat crime. Gov. JB Pritzker (D-IL) responds; a federal judge rules President Trump and Defense Secretary Pete Hegseth violated federal law by using the U.S. military to help carry out law enforcement activities in…
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Chris Best of Substack on the Future of Media
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46:23What if the future of media isn’t controlled by algorithms or legacy institutions—but by independent voices building directly with their audiences? In this episode, Erik Torenberg is joined by Chris Best, cofounder and CEO of Substack, along with a16z general partners Katherine Boyle and Andrew Chen. We trace the origin story of Substack and its cu…
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Venture capital has powered companies like Facebook and TikTok—but what if that same urgency fueled America’s defense and industrial base? Katherine Boyle, General Partner at Andreessen Horowitz and cofounder of the firm’s American Dynamism practice, argues this is the biggest business opportunity of our time. In this conversation from The Shawn Ry…
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Weekend Edition: Intel Corporation, Israel - Hamas Conflict, and the 20th Anniversary of Hurricane Katrina
31:11
31:11
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31:11In this weekend's episode, three segments from this past week's Washington Journal. First, a discussion with Competitive Enterprise Institute's Ryan Young, about the Trump Administration's purchase of a 10% stake in the Intel corporation. Then, Nadia Bilbassy-Charters (bill-bey-zee) of Al Arabiya News Channel and Jacob Magid (MAG-id) of the Times o…
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20th Anniversary of Hurricane Katrina hitting Gulf Coast; President Trump cuts $4.9 billion in foreign aid through a 'pocket rescission', bypassing a Congressional vote
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54:33On the 20th anniversary of Hurricane Katrina devastating Louisiana,Mississippi and other parts of the Gulf Coast, tributes to those lost, pride in the rebuilding and recovery, and thoughts of preparing for future storms; President Donald Trump says he will cut $4.9 billion for foreign aid through a 'pocket rescission', which will not give Congress …
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Health Secretary Robert F. Kennedy, Jr. defends firing CDC Director Susan Monarez just a few weeks after she is sworn-in
56:51
56:51
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56:51Health Secretary Robert F. Kennedy, Jr. says the Centers for Disease Control and Prevention Director Susan Monarez was removed from her position because she did not align with President Donald Trump's “Make America Healthy Again” (MAHA) agenda. She is challenging the dismissal and her lawyers say she chose "protecting the public over serving a poli…
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In this interview from the 20VC podcast, Martin Casado (a16z General Partner) joins Harry Stebbings to unpack the state of AI, the rise of coding models, the future of open vs. closed source, and how value is shifting across the stack. Martin offers a candid view of the opportunities and dangers shaping AI and venture capital today. Resources: Find…
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Gunman shoots through church windows in Minneapolis, killing two children, injuring others, at mass celebrating new year of Catholic school; Gov. Walz says students were met with 'evil and horror and death ...
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52:17A gunman kills two children and injures 17 other children and adults at a Catholic school in Minneapolis during a mass celebrating the first day of school before killing himself. FBI Director Kash Patel says it is being investigated as an act of domestic terrorism and hate crime against Catholics; Washington, DC Mayor Muriel Bowser says the three w…
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What are real consumers actually doing with AI today? In this episode, a16z consumer investors Olivia Moore and Justine Moore break down the fifth edition of our Consumer AI 100, a biannual ranking of the most used AI-native web and mobile products across the globe. Timecodes: 0:00 Introduction 1:45 New Companies & Trends 3:32 Companionship & Creat…
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Federal Reserve Governor Lisa Cook to sue after President Donald Trump says he is firing her for alleged mortgage fraud
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47:58Lawyers for Federal Reserve Governor Lisa Cook say she will sue after President Donald Trump said he is firing her after allegation of mortgage fraud. Cook says the president does not have that power; President Trump says he wants anyone who commits a murder in Washington, DC to be given the death penalty. DC Council repealed the death penalty in 1…
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