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Big Things Podcast

Mitzi Payne & Mike Payne

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A weekly show where we talk about the big things we're watching in marketing, social media, pop culture and sports. We also talk through signals we’re seeing that could inform the future of digital marketing. You can catch the podcast every Friday wherever you listen or watch it on YouTube. Be sure to follow us on Instagram or TikTok for updates on every episode.
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Riisfeldt Neurology Education

Dr Thomas D. Riisfeldt

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Welcome to Riisfeldt Neurology Education, a not-for-profit, free open access project with a philosophical touch exploring all areas of clinical neurology! I’m your host, Dr Thomas D. Riisfeldt, an Australian neurologist, epileptologist and neurophysiologist/neuromuscular specialist, and also a physician, philosopher and bioethicist. This podcast is aimed at medical students, neurologists/physicians and their trainees, and any other medical, nursing or allied health professionals involved in ...
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The Breathwork Club

thebreathworkclub

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A podcast designed to help you connect with your breathing. Each episode will bring you simple and accessible tips and techniques to help you harness the amazing resource that is our breath. Featuring music from Irish composer Gareth Quinn Redmond
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If you see something stupid--say something, Stupid! All of the stories you hear on this podcast are true. None of the names have been changed because no one is innocent from stupidity! Join ”Insane” Erik Lane on a journey through his stupid world where he, with the help of his Insane Florida Nephew, ”Pancho Guero”, will astound your with just how stupid humanity can be! You’ll hear tales of stupid criminal, stupid laws, stupid politicians, and stupid stunts...plus so much more! For the most ...
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This episode continues our run of journal club episodes, this time looking at whether SGLT2 inhibitors used for type 2 diabetes mellitus have any associated reduction in dementia (such as Alzheimer’s disease and vascular dementia) and Parkinson’s disease, therefore falling into these respective series as well. The content of this episode is best su…
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(00:00:00) Inflantion Hits Santa's Cookies, GameStop's Trade Anything Day, and Grandma's Birthday Cake Fire (00:02:03) A Piece of My Mind (00:06:27) A Pancho-less Week of Stupidity We are "Pancho-less" for this FINAL 2025 Episode...Pancho took a week of vacation so he could contract strep throat so this Weekend Episode is not only late being publis…
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First up on the podcast, Online News Editor David Grimm joins host Sarah Crespi to talk about this year’s best online news stories—top performers and staff picks alike. Together they journey the scientific gamut, from bird feeders’ influence on hummingbird beak evolution to the use of “artificial spacetimes” to guide tiny robots through their envir…
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(00:00:00) Sniifing Farts, DoorDash-dardly Deed, Dead Hog Smorgasboard (00:00:43) Midweek BONUS Stupidity (01:01:26) Insane Week In Review (01:09:46) Genius Awards Increase your brain power ...not from Reader's Digest, but from your own "air biscuits"! If you're getting food from a DoorDasher, better have your Ring Camera rolling! Internet influenc…
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This instalment brings another journal club episode, this time in the Parkinson’s disease and movement disorders series, focussing on the diagnostic accuracy of dopamine uptake scans (DAT SPECT; DaTscan) for Parkinson’s disease and the other primary extrapyramidal disorders/Parkinson’s plus syndromes (progressive supranuclear palsy, PSP; multiple s…
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(00:00:00) Overthinking Parenthood, Russian Bird-Biodrones, and Pit Porn (00:01:40) A PIece of My Mind (00:08:11) Pancho Guero My Insane FL Nephew (01:15:24) Ask Pancho (01:36:48) Insane Game Show (01:51:51) Coming Next Episode There is a degree of trepidation for new parents but when overthinking becomes the norm, it's time for a reality check. We…
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First up on the podcast, we’ve likely only found about half the so-called city-killer asteroids (objects more than 140 meters in diameter). Freelance science journalist Robin George Andrews joins host Sarah Crespi to discuss the upcoming launch of NASA’s Near-Earth Object Surveyor, an asteroid hunter that will improve our ability to look for large …
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The Grinch is alive & arrested in Pittsburgh after trying to "end Christmas". A racoon is in AA after breaking into a liquor store & slurping up enough booze to pass out in the bathroom. A fireman is being "hosed" for playing with his "fire hose" in multiple locations. In this Midweek BONUS Episode... Man Set His Family's Home On Fire Following Arg…
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Nature can be so beautiful until it comes through your car's windshield as you travel down the freeway! My Insane FL Nephew, "Pancho Guero" will graphically tell you how one woman from NC got a front row seat experience. Going through airport security is stressful enough without the realization that those TSA officers operating the scanners can see…
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First up on the podcast, Science celebrates 100 years of quantum mechanics with a special issue covering the past, present, and future of the field. News Contributing Correspondent Zack Savitsky joins host Sarah Crespi to talk about a more philosophical approach to quantum physics and the mysterious measurement problem. Next on the show we have Ann…
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Nothing spells "yummy" like squeezable gravy in a bottle. But the ingenious people a Heinz had to add the word, "leftover" to really add some pizazz. Polk Co., FL Sheriff Grady Judd has a visual for what it means to be "buck naked", thanks to a FL man claiming to be doing a TikTok challenge...without his phone. In a stunning display of the definiti…
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We’re thrilled to present our first journal club episode, focusing on tenecteplase for ischaemic stroke in the 4.5-24 hour time window in patients with large vessel occlusions (LVOs) in whom mechanical thrombectomy is not an available option (the TRACE-III study, published in the New England Journal of Medicine; NEJM in 2024). This is a landmark st…
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First up on the podcast, when will the world hit peak carbon emissions? It’s not an easy question to answer because emissions cannot be directly measured in real time. Instead, there are proxies, satellite measures, and many, many calculations. Staff Writer Paul Voosen joins host Sarah Crespi to discuss how close we are to the top of carbon mountai…
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Hope you’re ready for an important one! In this next instalment in the stroke & cerebrovascular diseases series we discuss how to effectively run a stroke call/code stroke, focussing on establishing the time last seen well (or midpoint of sleep), the baseline function (modified Rankin scale; mRS), stroke deficits (National Institutes of Health Stro…
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If you're going to develop feelings for your AI Chatbot, shouldn't you also let it have your children? Some people seem to think so. A lot of the psychotic murderers hear voices in their heads telling them to kill people. This guy hears it from bugs. If you're going to sneak birds out of a country, do you think putting them in your shorts next to y…
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I'm all about proper protocol but when parents have to start granting consent from their newborn before they can remove a poopy diaper, protocol goes down the commode. You can now chat with the Almighty right from your smartphone and pray to Jesus just like you would do a Google search! Windmills look so picturesque when seen against a sunset. But …
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First up on the podcast: the mysterious fate of Europe’s Neolithic farmers. They arrived from Anatolia around 5500 B.C.E. and began farming fertile land across Europe. Five hundred years later, their buildings, cemeteries, and pottery stopped showing up in the archaeological record, and mass graves with headless bodies started to appear across the …
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If you thought things could get tense when a line of women are trying to get into a bathroom, wait until you hear about what happens when a bunch of men at a Bass Pro Shop need to potty! You've heard stories of naked gardening, but now you're treated in this episode to naked chainsawing. But the neighbors were not amused. Starbucks Coffee may not g…
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An officer with the City of Buffalo couldn't keep his "Breakfast" contained and it went after a woman in his neighborhood. A man in the UK couldn't stop looking at boobs after his eye surgery. A police chief couldn't stop helping prostitutes get off the street and got caught up in a sting operation. My Insane FL Nephew, "Pancho Guero" and I will ex…
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First up on the podcast, Online News Editor David Grimm joins host Sarah Crespi for a rundown of online news stories. They talk about lichen that dine on dino bones, the physics of the lip-out problem in golf, and a brain-computer interface that can decode a tonal language (Chinese) from brain waves. Next on the show, Jeremy Munday, a professor of …
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Halloween really brings out the stupid in people and we have some examples. Also a judge saw too much evidence displayed by a police officer in a Zoom hearing when it was revealed that the cop was revealing more than he focused on. Attention Walmart shopper...loose monkey in a diaper in the Halloween department. A ticket in the hand is better than …
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In this next episode in the movement disorders and Parkinson’s disease series, we begin with a brief overview of the mechanisms of action of the medications used to treat Parkinson’s disease, before focusing on five common and important ward dilemmas encountered in the management of patients with Parkinson’s disease: (1) the patient is unable to ta…
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It's bad enough to cheat on a college paper by using artificial intelligence. But when the profs caught the cheaters, the profs began getting letters of apology....ony to later discover that the apology letters were also written with AI. Riding a roller coaster to experience the thrill of speed and gravity defiance was suddenly interruped for one w…
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First up on the podcast, Contributing Correspondent Sofia Moutinho visited the Xingu Indigenous territory in Brazil to learn about a long-standing collaboration between scientists and the Kuikuro to better understand early Amazon communities. Next on the show, we visit the Pacific pocket mouse recovery program at the San Diego Zoo Wildlife Alliance…
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You can pick your friends and you can pick your nose and now you can pick up some booger candy ...but I wouldn't recommend you put that in your nose. Someone who had more spare time on their hands than time would allow wondered what Glen Campbell's 1975 hit, "Rhinestone Cowboy" would sound like if it were done by an 80's glam metal band. So, he use…
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We’re thrilled to announce the first episode in our movement disorders & Parkinson’s disease series (also continuing our clinical method series), beginning with a discussion of how to perform an extrapyramidal examination, particularly in the context of suspected Parkinson’s disease, progressive supranuclear palsy (PSP), multiple system atrophy (MS…
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Halloween sure brings out the stupid in people and this is the place to find out how. Monkeys one the loose both virtually and literally from NJ to MS. My Insane FL Nephew, "Pancho Guero" who considers himself a "Mexican-In-Law" has news about how New Yorkers are losing their minds over a restaurant that triggers all the left-wingnuts. 67. In This …
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First up on the podcast, increased carbon dioxide emissions sink more acidity into the ocean, but checking pH all over the world, up and down the water column, is incredibly challenging. Staff Writer Paul Voosen joins host Sarah Crespi to discuss a technique that takes advantage of how sound moves through the water to detect ocean acidification. Ne…
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The second episode in the neuro-otology and vertigo series takes a step back to review the clinical approach to the patient presenting with the notoriously misinterpreted symptom of ‘dizziness’, before reviewing the best way to classify common causes of vertigo into either acute persistent vertigo vs. episodic vertigo (which can in turn be triggere…
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Just when you thought Kim Kardashian couldn't get any more stupid ideas, we now have an option to buy our girl a frisky thong with pubic hair. A 30-year long mystery has plagued the Missoula campus of the University of Montana that finds a pumpkin somehow impaled atop of a spire high above the Main Hall. No one knows who, why, or how. Would you tru…
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We’ve got another surprise installed for you today… the first episode in the neuro-otology and vertigo series! (Again as an overlap with our ongoing clinical method series). This episode focuses on the HiNTs+ examination in distinguishing central from peripheral causes of an acute vestibular syndrome, in particular distinguishing a posterior circul…
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Having the insaciable urge to lick something should lead a person to an ice cream cone or a lolipop--not frogs. But some people are just stupid, as you will discover when my Insane FL Nephew Pancho Guero will tell you. A lot of smart beds got stupid when the massive outage occurred at Amazon Web Services (AWS), leaving some night owls sleeping like…
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First up on the podcast, the Bering Sea’s snow crabs are bouncing back after a 50-billion-crab die-off in 2020, but scientists are racing to predict what’s going to happen to this important fishery. Contributing Correspondent Warren Cornwall joins host Sarah Crespi to discuss what’s next for snow crabs. Next on the show, freelance producer Elah Fed…
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This is the first episode in the neurological procedures series… drum roll please… you guessed it, it’s the lumbar puncture (LP)! This episode describes at length the many indications for lumbar punctures (a super helpful procedure!), the contraindications and how to evaluate these, how to consent the patient, what equipment is required and recomme…
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Correction: 19:30 Visual threat testing is for testing visual fields when the patient isn't properly responding to your initial standard field testing (not for when there is already an established field deficit in a cooperative and responsive patient) Correction: 21:31 Should say "retrochiasmal components" (not "upper motor neuron components", oops…
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Imagine waking up to the smell of fresh coffee, bacon, or gasoline. Just pick what suits your fancy the next time you have a hotel stay. Some Holiday Inn Express hotels are introducing scent-based alarm clocks! Was this guy trying to keep his soup warm when he shoved what looks to be a 20-oz. THERMOS up his "exit ramp"? As my Insane FL Nephew, "Pan…
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First up on the podcast, Contributing Correspondent Kai Kupferschmidt takes a trip to Svalbard, an Arctic archipelago where ancient RNA viruses may lie buried in the permafrost. He talks with host Sarah Crespi about why we only have 100 years of evolutionary history for viruses such as coronavirus and influenza, and what we can learn by looking dee…
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This episode further continues our clinical method series by turning to the lower limb examination, focussing on tips and tricks to optimise your examination technique assessing inspection, tone, power, reflexes, sensation, coordination, stance and gait. The diagnostic utility of many of these examination components are critically discussed, and va…
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You might have been the victim of or the perputrator to the dating scam known as "catfishing" where you portray yourself as something you're not. Now this has evolved to the job hunting profession. When you say your wedding vows, you typically promise "to death do us part"...but can you also comimit "to DUI do us serve"? One couple did & ended up c…
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This episode continues our clinical method series by turning to the upper limb examination, focussing on tips and tricks to optimise your examination technique assessing inspection, tone, power, reflexes, sensation and coordination. This episode also introduces some neurophysiological and anatomical principles, and ties these in with key patterns e…
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First up on the podcast, producer Kevin McLean talks with Associate Online News Editor Michael Greshko about the impact of wildfires on wine; a couple horse stories, one modern, one ancient; and why educators are racing to archive government materials. Next on the show, research that took advantage of a natural experiment in unnatural lighting. Hos…
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Would you pick up a cup of "Graveyard Shift Coffee" on your way into the hospital to visit your terminally ill grandma? The Mayo Clinic would probably not endose this, so they booted the death-themed coffee truck from its parking lot. Would you spare the hangover by drinking a mocktail made from mushrooms? Would you consider a career in corrections…
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Forget being a mail-order bride, that's so old-fashioned. Be a Billboard Bride aan tell everyone you're "available" with an online application. One way to teach your neighbors about not feeding your pets is to EAT them. The pets. Not the neighbors. A Florida man did just that with his peacocks. My Insane FL Nephew, "Pancho Guero", thinks ESPN shoul…
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This episode is part 2 of the session taking a deep dive into the specific examination techniques for each cranial nerve, focussing on pearls and pitfalls for optimal testing, along with focussing on linking the examination to relevant neurological pathologies for contextualisation and to aid memorisation. This episode, part 2, focuses on cranial n…
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First up on the podcast, Staff Writer Robert F. Service joins host Sarah Crespi to talk about a boom in nuclear medicine, from new and more powerful radioisotopes to improved precision in cancer cell targeting. Next on the show, we talk about why we sigh. Maria Clara Novaes-Silva, a doctoral student at ETH Zürich, discusses how deep breaths cause m…
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This episode begins with a description of the examinable components of each cranial nerve, and how they are best grouped together for an efficient and logical examination, before taking a deep dive into the specific examination techniques for each cranial nerve, focussing on pearls and pitfalls for optimal testing, along with focussing on linking t…
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When you hit a "home run" at an In-n-Out Burger, you're not coming in first. When you crash a Delta Sky Lounge without credentials, you're are going out first. When you change a baby's diaper, you really don't know what's coming out first. You'll understand all of these when you check out this Midweek BONUS Episode... In this Midweek BONUS Episode.…
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This episode discusses how to semiologically distinguish nocturnal hypermotor (hyperkinetic) seizures typical of sleep-related hypermotor epilepsy (SHE, formerly nocturnal frontal lobe epilepsy, NFLE) from the two main differential diagnoses for paroxysmal sleep behaviours, namely exaggerated/confusional physiological arousals and various parasomni…
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This short (and less serious!) episode explains the many hidden details in our intricate logo, with a few perhaps unexpected learning points discussed along the way, including a brief discussion of different ways of acquiring an electroencephalogram (EEG) recording, the four radiological locations for typical multiple sclerosis (MS) lesions, some o…
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This episode discusses how to distinguish a bilateral tonic-clonic seizure (of generalised, focal or unknown onset) from a convulsive syncope and from a psychogenic non-epileptiform spell/seizure (PNES, as part of functional neurological disorder, FND). To do so, we focus on key aspects of the semiology of the episode in addition to other relevant …
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