Best Remyelination Podcasts (2025)

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Investigating autoimmune mechanisms underlying progressive supranuclear palsy 25:36

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4d ago25:36

25:36

Welcome to the 30th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Professor Gabor G Kovacs of the Brain article entitled: Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy Listen to the fasci…

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Repairing MS: The Quest to Rebuild Myelin 39:30

20d ago39:30

39:30

The quest to repair the damage caused by multiple sclerosis is gaining momentum, with scientists working to restore lost function and slow progression by rebuilding myelin—the protective coating of nerve cells. Within the brain and spinal cord, immature myelin-making cells called OPCs hold promise, but need the right signals to mature into oligoden…

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Can transcriptional analysis detect efficient remyelination in multiple sclerosis? 20:34

1M ago20:34

20:34

Welcome to the 29th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author of the Brain article entitled: Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis We are joined by Alida Chen for an interesting…

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Parenting with MS: Finding Strength, Joy, and Resilience 31:36

1M ago31:36

31:36

Parenting can be both a beautiful adventure and a demanding test. For those living with multiple sclerosis, the joys of raising children often come with added challenges—fatigue, changes in routine, and questions about how MS may affect family life. Despite these obstacles, many parents with MS find that their journey brings deeper meaning, resilie…

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Repair, Reset, Reimagine: Stem Cell Therapies for Multiple Sclerosis 45:40

2M ago45:40

45:40

Stem cells have the extraordinary ability to transform into different types of cells and renew themselves—offering new hope in the treatment of multiple sclerosis. One of the most advanced approaches—autologous hematopoietic stem cell transplantation (AHSCT)—involves collecting a patient’s own bone marrow stem cells, using chemotherapy to wipe out …

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Beyond the Prescription Pad: Complementary and Alternative Medicine for MS 40:50

3M ago40:50

40:50

Most people living with multiple sclerosis explore complementary or alternative medicine (CAM) as part of their care. Complementary therapies—such as supplements, special diets, or mind-body practices—are used alongside disease-modifying treatments (DMTs), while alternative therapies are chosen instead of them. In this episode, we dive into commonl…

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Nephrology Meets Neurology: how kidney health links to neurodegeneration 36:36

3M ago36:36

36:36

Welcome to the 28th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with three authors of the Brain article entitled: The relationship between kidney health and neurodegenerative diseases Ms Melody Zuo, Dr Le Chang and Professor Sarah A Gagliano Taliun grace the …

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Boosting Brain Health: Blueprint for MS 35:40

4M ago35:40

35:40

Living with multiple sclerosis brings unique challenges to brain health, but there are powerful steps you can take to support and protect your mind. Exercise not only improves endurance and reduces fatigue, but also helps rewire brain networks to promote resilience. Restorative sleep is essential, as it helps clear inflammation in the brain—so addr…

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Secondary Progressive MS: Next Chapter 37:47

4M ago37:47

37:47

Figuring out if your multiple sclerosis is changing from the relapsing remitting to the secondary progressive stage can be murky. Signs of progression are discussed like slower walking and worsening memory. The underlying reasons for progression are revealed including nervous system injury, remyelination failure, chronic inflammation and aging. Pra…

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Understanding traumatic brain injury with high dimensional proteomic analysis 24:48

5M ago24:48

24:48

Welcome to the 27th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author Dr Lucia M Li of the Brain article entitled: High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury Listen to the fascinating insigh…

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Glymphatic homeostasis in heart failure- more in but not out? 32:51

6M ago32:51

32:51

Welcome to the 26th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author Dr Marios Kritsilis and senior author Associate Professor Iben Lundgaard of the Brain article entitled: Loss of glymphatic homeostasis in heart failure This academic duo from Lu…

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Adult congenital myasthenic syndromes - discussing the diagnostic dilemma and other findings from a longitudinal cohort 21:37

7M ago21:37

21:37

Welcome to the 25th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Tanya Stojkovic of the Brain article entitled: Congenital myasthenic syndromes in adults: clinical features, diagnosis and long-term prognosis Dr Stojkovic discusses finding…

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Nociceptors are functionally male or female: from mouse to monkey to man? 38:00

8M ago38:00

38:00

Welcome to the first episode of 2025 for The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Frank Porreca of the Brain article entitled: Nociceptors are functionally male or female: from mouse to monkey to man? Dr Porreca discusses important findings into…

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Academic neurology in the UK: a plea to turn away from the precipice 28:59

10M ago28:59

28:59

Welcome to the 23nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode, we bring on authors Dr Helen Devine and Professor Simon Mead to discuss their opinion article entitled: Academic neurology in the UK: a plea to turn away from the precipice. The discussions covers the growing conc…

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Can Epilepsy surgery improve or even reverse cognitive deficits in children with epilepsy? 27:52

12M ago27:52

27:52

Welcome to the 22nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Torsten Baldeweg of the Brain article entitled: Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline? Dr Baldeweg discusses fascina…

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Mind Over MS: Strategies for Staying Positive 38:31

12M ago38:31

38:31

Facing the first symptoms and a new multiple sclerosis diagnosis can be terrifying, leaving you with a flood of questions about your future. How do you navigate your career, relationships, and whether to start a family? The uncertainty can be overwhelming, but you don’t have to go it alone. Support from loved ones and connections with others living…

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Diagnosing Multiple Sclerosis 35:25

1y ago35:25

35:25

In this era of highly effective treatments, early intervention for multiple sclerosis can be life changing. However, the wide range of initial symptoms often leads to many people being undiagnosed or misdiagnosed, leaving them without the proper care for years. In this podcast episode, we'll discuss the early signs of MS and the key tests, such as …

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MS & The Spinal Cord 39:50

1y ago39:50

39:50

The spinal cord serves as the main communication highway between the brain and body. Did you know that 80% of people with multiple sclerosis have spinal cord lesions on MRI? These lesions can disrupt specific neural pathways, leading to common MS symptoms like numbness, weakness, impaired coordination, balance issues, bladder problems, constipation…

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Anti-IgLon5 disease risk is mediated by HLA-DQB1*05 subtypes: when neuroimmunology meets neurodegeneration 34:26

1y ago34:26

34:26

Welcome to the 21th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with the first author Dr Selina Yogeshwar of the Brain article entitled: HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease Dr Yogeshwar offers exciting insight into the…

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The essential Role of PAK2 in Myelinating the Peripheral Nervous System 25:44

1+ y ago25:44

25:44

Welcome to the 20th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with the final author Dr Jun Li of the Brain article entitled: PAK2 is necessary for myelination in the peripheral nervous system How are peripheral nerve cells myelinated and what proteins are i…

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How is the gut microbiota related to cognition and hippocampal neurogenesis in Alzheimer's disease? 29:18

1+ y ago29:18

29:18

Welcome to the 18th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with first author author Dr Stefanie Grabrucker of the Brain article entitled: Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis How does lifestyle an…

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Uncommon Multiple Sclerosis Symptoms 35:54

1+ y ago35:54

35:54

Awareness of the more uncommon multiple sclerosis symptoms can lead to an earlier diagnosis and appropriate treatment. For instance, experiencing electrical shock sensations when bending the neck forward, known as Lhermitte’s sign, may indicate an attack on the cervical spinal cord. Likewise, excruciating bolts of pain across either side of the fac…

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Harnessing AI: Transforming MS Care 39:01

1+ y ago39:01

39:01

Prepare to be intrigued by the groundbreaking intersection of artificial intelligence (AI) and multiple sclerosis care! By combing through extensive databases, including genetic information and real patient records, AI can forecast with remarkable accuracy the likelihood of MS onset. In the near future, AI could even serve as a guiding light for cl…

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Do noradrenergic alterations in Parkinson’s disease indicate a therapeutic target? A combined PET & neuromelanin MRI study 22:38

1+ y ago22:38

22:38

Welcome to the 17th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. This episode features a discussion with senior author Dr Bénédicte Ballanger of the Brain article entitled: Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study Can this multi-modal…

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Navigating MS with Other Medical Conditions 42:17

1+ y ago42:17

42:17

Living with multiple sclerosis isn't just about managing the condition itself, but often involves navigating a myriad of additional health concerns known as comorbidities. Individuals with MS face a higher risk of experiencing new relapses when dealing with comorbidities like high cholesterol or depression. Furthermore, autoimmune diseases such as …

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Hormones and Multiple Sclerosis 38:26

1+ y ago38:26

38:26

Sex hormones, such as estrogens and testosterone, affect each individual's journey living with multiple sclerosis. While both genders face equal MS risk before puberty and after menopause, women experience up to three times higher risk during their reproductive years. Pregnancy generally brings less relapses, potentially attributed to high estriol …

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Altered brain glucose metabolism as a mechanism for delirium? 16:08

1+ y ago16:08

16:08

Welcome to the 16th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. We are very excited to feature a January issue Brain article, where we speak with senior author Dr Lasse M Giil entitled: Impaired glucose utilization in the brain of patients with delirium following hip fracture Delirium is a com…

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Revolutionizing Multiple Sclerosis Care: B-Cell Therapy 39:48

1+ y ago39:48

39:48

In a paradigm-shifting discovery, researchers uncovered that B cells, not T cells, wield significant influence on orchestrating neurological damage in MS. Join UCSF Professor Dr. Stephen Hauser as he shares the remarkable odyssey from hurdles to triumphs of developing B cell monoclonal antibody treatment for multiple sclerosis. Disease impact, safe…

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Recipe for Resilience: The Blind Cook and NMOSD 38:12

2y ago38:12

38:12

Christine Ha, an award-winning blind chef and restauranteur, shares her experience grappling with neuromyelitis optica spectrum disorder (NMOSD). Facing relapses with the inability to walk and feed herself that challenged her independence, she leaned on the support from family and friends. As she lost her sight due to optic neuritis in both eyes, M…

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Are there differences in the immune response among individuals of Black ethnicity with multiple sclerosis? 19:35

2y ago19:35

19:35

Welcome to the 15th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. We are very excited to feature our first article from Brain Communications, where we speak with first author Dr Kiel Telesford of the article entitled: Neuron-binding antibody responses are associated with Black ethnicity in multi…

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Exploring a genetic basis for disordered speech and language: FOXP2 mutations and striatal neurons 20:12

2y ago20:12

20:12

Welcome to the 14th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Fu-Chin Liu, senior author of the article entitled: Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons. This article explores a potential genetic basis for disordere…

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Making Strides: Enhancing MS Mobility 37:40

2y ago37:40

37:40

Wherever you are on your multiple sclerosis journey, there are many reasons to be optimistic about the future of mobility. Our experts, both holding doctorates in physical therapy, offer invaluable guidance on enhancing your walking abilities through targeted exercise and specialized therapy. Learn how to reduce the risk of falls, alleviate spastic…

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Multisite thalamic recordings to characterize seizure propagation in the human brain 28:29

2y ago28:29

28:29

Welcome to the 13th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Josef Parvizi, senior author of the article entitled: Multisite thalamic recordings to characterize seizure propagation in the human brain This article explores the role of the thalamus in seizure pro…

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MS Care Equity: Empowering Underserved Communities 35:18

2y ago35:18

35:18

Health equity represents the pursuit of the highest level of well-being for all individuals, ensuring that every person, regardless of their background, enjoys a fair and just opportunity to achieve their optimal health. Disparities exist within the multiple sclerosis community. It's a stark reality that Black individuals with MS face an increased …

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Bridging MS: Connecting You to Resources 39:20

2y ago39:20

39:20

Navigating life with multiple sclerosis? Gain valuable insights from MS insiders! Stanford nurse practitioner Jong-Mi Lee reveals strategies for accessing MS centers and maximizing available resources. Acquire valuable tips on various topics including overcoming mobility challenges, managing workplace issues, and receiving quality care despite insu…

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A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies 16:25

2y ago16:25

16:25

Welcome to the 12th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Nico Melzer, senior author of the article entitled: A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies This article explores expanding entity of GAD-65…

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MRI in MS: From Pixels to Progress 33:33

2y ago33:33

33:33

Step into the powerful realm of MRI imaging, providing us with an unparalleled view of multiple sclerosis. Discover how acute inflammation becomes vivid with contrast, and how various MRI sequences unveil the past battles fought within your brain and spinal cord. We'll explore advances in techniques, revealing brain shrinkage, gray matter disease a…

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Inside MS: Navigating Inflammation 38:02

2y ago38:02

38:02

Dive into a deeper understanding of the role of inflammation in causing injury to the brain and spinal cord in multiple sclerosis. It’s a journey marked by ups and downs, where the adaptive immune system composed of lymphocytes (T and B cells) attack myelin and the innate immune system clears damaged myelin. An immune cell called microglia can crea…

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RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain 26:42

2y ago26:42

26:42

Welcome to the 11th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Ted Price, senior author of the article entitled: RNA profiling of human dorsal root ganglia (DRG) reveals sex differences in mechanisms promoting neuropathic pain This article explores exciting findi…

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Multiple Sclerosis in Childhood 35:44

2+ y ago35:44

35:44

Yes, children can get multiple sclerosis. Children ages 12 and up are more typically affected and rarely before age 8. Awareness is essential for prompt diagnosis and treatment of pediatric-onset MS (POMS). Accurate diagnosis of multiple sclerosis in children requires screening for other conditions like MOG antibody-associated disease (MOGAD). Risk…

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Being Diagnosed with Multiple Sclerosis 32:22

2+ y ago32:22

32:22

Trying to confirm if you have multiple sclerosis can be a frustrating process. Dealing with a new diagnosis a MS can be overwhelming. Julian Gamboa and Dr. Jakai Nolan shed light on a positive path forward living with multiple sclerosis. Julian Gamboa shares his first symptoms of multiple sclerosis including spinning sensation and double vision. He…

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Earliest Stages of Multiple Sclerosis 41:09

2+ y ago41:09

41:09

Years before the first typical neurological symptoms of multiple sclerosis such as numbness or visual loss, individuals can have other symptoms that are often overlooked. This period of time is called the MS prodrome. During the prodrome phase, there is an increase in symptoms including skin, gastrointestinal and psychiatric issues. Research may le…

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Is My MS Controlled? 39:15

2+ y ago39:15

39:15

Knowing which MS changes are significant enough to warrant speaking up can be hard. Relapses can occur every 1-2 years without treatment, but much less frequently on disease-modifying treatment. Distinguishing between an actual relapse, a pseudorelapse or just brief worsening of symptoms (Uhthoff’s phenomenon) explained. Options for relapses such a…

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Tau positron emission tomography in preclinical Alzheimer’s disease 20:05

2+ y ago20:05

20:05

Welcome to the 11th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Philip Insel, lead author of the article entitled: Tau positron emission tomography in preclinical Alzheimer’s disease The article explores the utility of tau PET imaging in three independent, large c…

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Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis 29:16

2+ y ago29:16

29:16

Welcome to the 10th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Hideaki Nishihara and Britta Engelhardt, lead authors of the article entitled: Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis This was a transcontinental reco…

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COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis 24:58

2+ y ago24:58

24:58

Welcome to the 9th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we chat with Professor Robyn S. Klein, senior author of the article entitled: COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis This article explores the ongoing challenge to better under…

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Gene variant effects across sodium channelopathies predict function and guide precision therapy 31:49

2+ y ago31:49

31:49

Welcome to another episode of The Brain Podcast (first for 2023!) - the official podcast for the journal Brain and sister journal Brain Communications. In this episode, three guests joined us to discuss the article entitled: Gene variant effects across sodium channelopathies predict function and guide precision therapy. Professor Andreas Brunklaus …

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A daily temperature rhythm in the human brain predicts survival after brain injury 32:40

3y ago32:40

32:40

Welcome to the seventh episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we chat with Dr Nina M Rzechorzek, lead author of the article entitled: A daily temperature rhythm in the human brain predicts survival after brain injury We discuss how brain temperature was measured using inva…

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Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes 25:24

3y ago25:24

25:24

Welcome to The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications. In this episode we are joined by Professor Soon-Tae Lee to discuss his review article entitled Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes. Read the full article on the Brain webs…

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Cortical involvement and upcoming therapies in Multiple Sclerosis 22:01

3y ago22:01

22:01

Welcome to The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications. In this episode we are joined by Associate Professor Pavan Bhargava to discuss his review article entitled The contribution of B cells to the cortical damage in multiple sclerosis. Read the full article on the Brain website: https://do…