Technical interviews about software topics.
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Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.
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Step into the future, one day at a time, with Atometrix ByteSize! Your indispensable daily dose of the latest and greatest in AI, low-code, and all things tech. Each day, we whisk you through the most exciting updates, providing not just news, but insights, thought-provoking analysis, and of course, a sprinkle of humor. Every episode is a journey through the frontier of technology, exploring new developments in AI, the rapid evolution of low-code platforms, and the very tools that are rewrit ...
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Modern Enterprise Podcast is about the evolution of enterprises in the era of rapidly evolving technologies. In this podcast, we will talk about modern IT stacks, ML/AI, etc.. We will focus on helping end users understand the landscape and to help them figure out the right strategies needed for rapid innovation. Support this podcast: https://podcasters.spotify.com/pod/show/modernenterprise/support
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RAD is the best approach to develop prototypes swiftly for testing software functionalities without worrying about any effects on the end product. Businesses opt RAD approach as it requires little focus on the planning phase while enabling the team to design, review, and iterate features and functionalities quickly.
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TanStack and the Future of Frontend with Tanner Linsley
54:13
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54:13TanStack is an open-source collection of high-performance libraries for JavaScript and TypeScript applications, primarily focused on state management, data fetching, and table utilities. It includes popular libraries like TanStack Query, TanStack Table, and TanStack Router. These libraries emphasize declarative APIs, optimized performance, and deve…
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The Challenge of AI Model Evaluations with Ankur Goyal
44:22
44:22
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44:22Evaluations are critical for assessing the quality, performance, and effectiveness of software during development. Common evaluation methods include code reviews and automated testing, and can help identify bugs, ensure compliance with requirements, and measure software reliability. However, evaluating LLMs presents unique challenges due to their c…
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#352 ‒ Female fertility: optimizing reproductive health, diagnosing and treating infertility and PCOS, and understanding the IVF process | Paula Amato, M.D.
2:23:28
2:23:28
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2:23:28View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter This is part two of a two-part mini-series on fertility and reproductive health. Paula Amato is a leading expert in female reproductive health and infertility, widely recognized for her contributions to advancing ferti…
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Modern Distributed Applications with Stephan Ewen
41:02
41:02
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41:02A major challenge with creating distributed applications is achieving resilience, reliability, and fault tolerance. It can take considerable engineering time to address non-functional concerns like retries, state synchronization, and distributed coordination. Event-driven models aim to simplify these issues, but often introduce new difficulties in …
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Agentic AI is seen as a key frontier in artificial intelligence, enabling systems to autonomously act, adapt in real-time, and solve complex, multi-step problems based on objectives and context. Unlike traditional rule-based or generative AI, which are limited to predefined or reactive tasks, agentic AI processes vast information, models uncertaint…
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#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.
2:19:12
2:19:12
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2:19:12View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter This is part one of a two-part mini-series on fertility and reproductive health, with next week's guest, Dr. Paula Amato, focusing on the female side of the equation. Paul Turek is a world-renowned expert in male ferti…
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51
Chip Design in the AI Era with Thomas Andersen
50:15
50:15
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50:15Synopsys is a leading electronic design automation company specializing in silicon design and verification, as well as software integrity and security. Their tools are foundational to the creation of modern chips and embedded software, powering everything from smartphones to cars. Chip design is a deeply complex process, often taking months or year…
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51
OpenTofu with Cory O’Daniel and Malcolm Matalka
47:58
47:58
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47:58OpenTofu is an open-source alternative to Terraform, designed for managing infrastructure as code. It enables users to define, provision, and manage their cloud and on-premises resources using a declarative configuration language. OpenTofu was created to ensure an open and community-driven approach to infrastructure tooling, and it emphasizes compa…
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#350 ‒ Injury prevention, recovery, and performance optimization for every decade | Kyler Brown, D.C.
1:44:45
1:44:45
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1:44:45View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Kyler Brown is a sports rehab chiropractor who specializes in injury recovery, pre- and post-surgical rehabilitation, and guiding clients from rehab back to peak performance. As co-founder of the private training progr…
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51
Mojo and Building a CUDA Replacement with Chris Lattner
55:56
55:56
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55:56Python is the dominant language for AI and data science applications, but it lacks the performance and low-level control needed to fully leverage GPU hardware. As a result, developers often rely on NVIDIA’s CUDA framework, which adds complexity and fragments the development stack. Mojo is a new programming language designed to combine the simplicit…
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Building PostgreSQL for the Future with Heikki Linnakangas
42:12
42:12
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42:12PostgreSQL is an open-source database known for its robustness, extensibility, and compliance with SQL standards. Its ability to handle complex queries and maintain high data integrity has made it a top choice for both start-ups and large enterprises. Heikki Linnakangas is a leading developer for the PostgreSQL project, and he’s a co-founder at Neo…
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#349 - AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity
11:25
11:25
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11:25View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter dives deep into the topic of muscle mass and strength, examining their essential roles in both lifespan and healthspan. Drawing from over 30 hours of prior discussions wit…
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Cryptocurrency exchanges face unique security challenges that require specialized threat assessments and planning. Coinbase is a cryptocurrency exchange based in the United States. It was founded in 2012 and has evolved alongside cryptocurrency as a technology. Philip Martin is the Chief Security Officer at Coinbase. Prior to Coinbase, Philip built…
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Anthropic and the Model Context Protocol with David Soria Parra
51:02
51:02
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51:02The Model Context Protocol, or MCP, is a new open standard that connects AI assistants to arbitrary data sources and tools, such as codebases, APIs, and content repositories. Instead of building bespoke integrations for each system, developers can use MCP to establish secure, scalable connections between AI models and the data they need. By standar…
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#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.
2:13:28
2:13:28
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2:13:28View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Rachel Rubin is a board-certified urologist and one of the nation's foremost experts in sexual health. In this episode, she shares her deep expertise on the often-overlooked topic of women’s sexual health, exploring wh…
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Grand Theft Auto III on the Dreamcast with Falco Girgis and Stef Kornilios Mitsis Poiitidis
47:40
47:40
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47:40Grand Theft Auto III is a 2001 an open-world action-adventure game developed by Rockstar Games and it had a profound impact on both gaming and popular culture. Its success cemented video games as a dominant form of entertainment and storytelling, and paved the way for future blockbuster franchises. The game was also a technological milestone that r…
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Polypane is a specialized web development browser that simplifies creating and testing modern websites. A key feature is that it provides multiple screen sizes at once, with synchronized scrolling and interactions, so developers can test different layouts and breakpoints simultaneously. Polypane also focuses on accessibility tools, real-time previe…
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#347 – Peter’s takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly ...
33:20
33:20
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33:20View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from his discussions with Jeff English on…
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LiveKit is a platform that provides developers with tools to build real-time audio and video applications at scale. It offers an open-source WebRTC stack for creation of live, interactive experiences like video conferencing, streaming, and virtual events. LiveKit has gained significant attention for its partnership with OpenAI for the Advanced Voic…
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SED News: CoreWeave IPO, Anthropic’s MCP, and Microsoft Turns 50
46:15
46:15
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46:15Welcome to the pilot episode of SED News, a new podcast series from Software Engineering Daily. Join hosts Gregor Van and Sean Falconer as they break down the week’s most important stories in software engineering, machine learning, and developer culture. In this episode, Gregor and Sean discuss the CoreWeave IPO and the company’s recent acquisition…
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#346 - Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H.
2:05:50
2:05:50
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2:05:50View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Susan Desmond-Hellmann is a physician and scientist whose remarkable career has spanned clinical medicine, oncology, biotech innovation, and global health leadership. In this episode, Susan shares insights from her jou…
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AI tools are transforming how developers write code, and although it’s difficult to pinpoint how much code is now AI-generated code, estimates suggest it’s between 20% and 40%, and this figure is poised to grow in the coming years. This evolution has given rise to a new coding paradigm in which developers act as directors, guiding and refining AI-g…
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Glean is a workplace search and knowledge discovery company that helps organizations find and access information across various internal tools and data sources. Their platform uses AI to provide personalized search results to assist members of an organization in retrieving relevant documents, emails, and conversations. The rise of LLM-based agentic…
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#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.
2:47:06
2:47:06
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2:47:06View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Sean Mackey is a professor of pain medicine at Stanford University and the director of the Stanford Systems Neuroscience and Pain Lab, where his research explores the neural mechanisms of pain and the development of no…
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Turing Award Special: A Conversation with Martin Hellman
41:03
41:03
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41:03Martin Hellman is an American cryptographer known for co-inventing public-key cryptography with Whitfield Diffie and Ralph Merkle in the 1970s. Their groundbreaking Diffie-Hellman key exchange method allowed secure communication over insecure channels, laying the foundation for modern encryption protocols. Hellman has also contributed to cybersecur…
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Prometheus and Open-Source Observability with Eric Schabell
46:06
46:06
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46:06Modern cloud-native systems are highly dynamic and distributed, which makes it difficult to monitor cloud infrastructure using traditional tools designed for static environments. This has motivated the development and widespread adoption of dedicated observability platforms. Prometheus is an open-source observability tool designed for cloud-native …
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#344 - AMA #70: Nicotine: impact on cognitive function, performance, and mood, health risks, delivery modalities, and smoking cessation strategies
21:47
21:47
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21:47View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter dives deep into nicotine—a topic increasingly debated both scientifically and publicly. He clarifies the critical differences between nicotine and tobacco, highlighting wh…
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Turing Award Special: A Conversation with David Patterson
55:46
55:46
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55:46David A. Patterson is a pioneering computer scientist known for his contributions to computer architecture, particularly as a co-developer of Reduced Instruction Set Computing, or RISC, which revolutionized processor design. He has co-authored multiple books, including the highly influential Computer Architecture: A Quantitative Approach. David is …
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Uber’s On-Call Copilot with Paarth Chothani and Eduards Sidorovics
44:21
44:21
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44:21At Uber, there are many platform teams supporting engineers across the company, and maintaining robust on-call operations is crucial to keeping services functioning smoothly. The prospect of enhancing the efficiency of these engineering teams motivated Uber to create Genie, which is an AI-powered on-call copilot. Genie assists with on-call manageme…
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#343 – The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions | Sanjay Mehta, M.D.
2:12:12
2:12:12
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2:12:12View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Sanjay Mehta is a radiation oncologist with over 25 years of experience, and is currently the president of Century Cancer Centers in Houston, Texas (drsanjaymehta.com). In this episode, Sanjay explores the rapidly evol…
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Turing Award Special: A Conversation with John Hennessy
38:53
38:53
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38:53John Hennessy is a computer scientist, entrepreneur, and academic known for his significant contributions to computer architecture. He co-developed the RISC architecture, which revolutionized modern computing by enabling faster and more efficient processors. Hennessy served as the president of Stanford University from 2000 to 2016 and later co-foun…
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Sourcegraph and the Frontier of AI in Software Engineering with Beyang Liu
44:19
44:19
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44:19Sourcegraph is a powerful code search and intelligence tool that helps developers navigate and understand large codebases efficiently. It provides advanced search functionality across multiple repositories, making it easier to find references, functions, and dependencies. Additionally, Sourcegraph integrates with various development workflows to st…
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#342 ‒ Aging well: Peter shares strategies for improving longevity with residents at a senior living center
43:33
43:33
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43:33View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this special episode of The Drive, Peter joins a unique conversation inspired by his daughter’s volunteer experience at a senior care center, where she formed meaningful relationships with residents curious about he…
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Turing Award Special: A Conversation with Jeffrey Ullman
37:45
37:45
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37:45Jeffrey Ullman is a renowned computer scientist and professor emeritus at Stanford University, celebrated for his groundbreaking contributions to database systems, compilers, and algorithms. He co-authored influential texts like Principles of Database Systems and Compilers: Principles, Techniques, and Tools (often called the “Dragon Book”), which h…
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Knowledge Graphs as Agentic Memory with Daniel Chalef
53:39
53:39
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53:39Contextual memory in AI is a major challenge because current models struggle to retain and recall relevant information over time. While humans can build long-term semantic relationships, AI systems often rely on fixed context windows, leading to loss of important past interactions. Zep is a startup that’s developing a memory layer for AI agents usi…
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#341 - Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D.
2:05:16
2:05:16
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2:05:16View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Ashley Mason is a clinical psychologist and an associate professor at UCSF, where she leads the Sleep, Eating, and Affect (SEA) Laboratory. In this episode, Ashley provides a masterclass on cognitive behavioral therapy…
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Remix is a full-stack, open-source web framework that was developed by the creators of the popular React Router library. It focuses on features such as server-side rendering and efficient data loading, and it emphasizes developer experience. Ryan Florence is a co-creator of React Remix and in this episode he speaks with Josh Goldberg about the Remi…
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Turing Award Special: A Conversation with Jack Dongarra
49:31
49:31
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49:31Jack Dongarra is an American computer scientist who is celebrated for his pioneering contributions to numerical algorithms and high-performance computing. He developed essential software libraries like LINPACK and LAPACK, which are widely used for solving linear algebra problems on advanced computing systems. Dongarra is also a co-creator of the TO…
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#340 - AMA #69: Scrutinizing supplements: creatine, fish oil, vitamin D, and more—a framework for understanding effectiveness, quality, and individual need
24:36
24:36
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24:36View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores the complex world of supplements by introducing a practical framework for evaluating their effectiveness and relevance to individual health needs. Rather than pro…
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Quantum Computing at Rigetti with David Rivas
53:03
53:03
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53:03Rigetti Computing is an American company specializing in quantum computing, founded in 2013. The company develops quantum processors and hybrid quantum-classical computing systems, and aims to make quantum computing more accessible for research and commercial applications. David Rivas is the CTO at Rigetti Computing. He joins the podcast with Kevin…
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The State of the Ethereum Blockchain with Andrew Koller
41:13
41:13
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41:13Ethereum is a decentralized blockchain platform that was created by Vitalik Buterin and Gavin Wood in 2015. It uses a cryptocurrency called Ether as its native token to power transactions and operations on the Ethereum network. Ethereum’s proponents envision a future where the network forms the foundation for a second platform layer, called L2, whe…
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#339 - Unpacking trauma: How early wounds shape behavior and the path toward healing | Jeff English
2:02:11
2:02:11
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2:02:11View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Jeff English is a trauma-focused clinical counselor with extensive experience working with adults, teens, families, and groups across various settings, including career counseling, life coaching, addiction recovery, pr…
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StackHawk and Shift-Left API Security with Scott Gerlach
46:08
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46:08APIs are a fundamental part of modern software systems and enable communication between services, applications, and third-party integrations. However, their openness and accessibility also make them a prime target for security threats, and this makes APIs a growing focus on software teams. StackHawk is a company that scans and monitors source code …
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NVIDIA RAPIDS and Open Source ML Acceleration with Chris Deotte and Jean-Francois Puget
42:06
42:06
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42:06NVIDIA RAPIDS is an open-source suite of GPU-accelerated data science and AI libraries. It leverages CUDA and significantly enhances the performance of core Python frameworks including Polars, pandas, scikit-learn and NetworkX. Chris Deotte is a Senior Data Scientist at NVIDIA and Jean-Francois Puget is the Director and a Distinguished Engineer at …
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#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4
27:41
27:41
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27:41View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from his discussions on diverse topics su…
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Browser security aims to protect users from cyber threats encountered online, such as phishing, malicious extensions, and malware. It’s a complex, multifaceted challenge that’s increasingly important as cloud-based tools, SaaS platforms, and collaborative applications become the backbone of modern workflows. Jeswin Mathai is the Chief Architect at …
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Troubleshooting Microservices with Julia Blase
43:00
43:00
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43:00A distributed system is a network of independent services that work together to achieve a common goal. Unlike a monolithic system, a distributed system has no central point of control, meaning it must handle challenges like data consistency, network latency, and system failures. Debugging distributed systems is conventionally considered challenging…
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#337 - Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D.
2:26:40
2:26:40
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2:26:40View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Ralph DeFronzo is a distinguished diabetes researcher and clinician whose groundbreaking work on insulin resistance has reshaped the understanding and treatment of type 2 diabetes. In this episode, Ralph shares insight…
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Vercel’s Developer Frameworks with Ary Khandelwal and Max Leiter
52:25
52:25
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52:25The availability of high-quality AI model APIs has drastically lowered the barriers developing AI applications. These tools abstract away complex tasks such as model deployment, scaling, data retrieval, natural language processing, and text generation. Vercel has developed a complementary set of tools for building AI web applications, including the…
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Docusign for Developers with Dan Selman and Larry Jin
45:10
45:10
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45:10Agreements and contracts are a fundamental innovation and govern everything from personal commitments to major financial decisions. They function as trusted artifacts to capture the nature of a commitment and provide clarity and accountability. Software has revolutionized many business functions, including the basic mechanics of digitally signing a…
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