Join Dr. Grigory Karmy M.D., a distinguished chronic pain management physician with over 20 years of experience, on a captivating journey through the world of pain relief in his podcast series. Delving into the latest regenerative medical treatments like PRP, stem cell injections, and prolozone therapy, alongside educational discussions on pain transmission and the latest medical innovations, Dr. Karmy shares invaluable insights and real-life stories, empowering listeners to find relief and ...
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Prolozone Podcasts

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Episode 22: Interview with Dr. Andrea Furlan - a Physician, Researcher and Educator on Lifestyle Based Approaches to Pain Management
55:37
55:37
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55:37Dr. Andrea Furlan is the closest thing we have to an influencer in the field of chronic pain management. She is a content creator who has a very popular YouTube channel and an author who has written several books for patients with chronic pain. She is also an educator who has developed programs for healthcare providers. Join Dr Karmy for an intervi…
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Episode 21: The Role of AI in Chronic Pain Research
46:15
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46:15Artificial Intelligence (AI) is all over the news with headlines promising that AI will replace all human workers or possibly even take over the world. Hype aside, how will AI impact pain research? Join me for a fascinating interview with Dr. Di Ieva, a neurosurgeon and computer scientist who is using AI to study chronic pain. If you have any quest…
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Episode 20: Zymedyne and the Search for New Medications for Pain
38:39
38:39
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38:39What is it like trying to discover new medication for chronic pain? Join Dr. Karmy for an interview with Dr. Chris Bladen, CEO of Zymedyne, a Calgary biotech start-up, to learn what it takes to bring a new medication for chronic pain to patients. Learn more about Zymedyne Theapeutics here: https://zymedyne.ca/ If you have any questions for Dr. Karm…
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Join Dr. Karmy for an interview with Dr. Warren Goldstein, a neurologist with extensive experience in headache management. In this episode, we will have an in-depth discussion about a new class of migraine medications that block CGRP neuropeptides. Are the risks worth the benefits? What about insurance coverage? Should you try this new class of med…
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Episode 18: A New Non Invasive Treatment for Lower Back Pain - HIFU
47:56
47:56
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47:56Traditionally, the Radio Frequency Ablation (RFA) procedure for chronic back pain requires approximately six injections with 2-4 inch needles followed by the insertion of heated probes to burn the nerves that supply joints of the spine called facet joints. What if you could do all that without the need for injections or heated probes? An innovative…
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Episode 17: Cortisone Side Effects You Did Not Know About!
7:10
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7:10In this episode, join Dr. Karmy as he discusses lesser-known side effects of cortisone injections. If you have any questions for Dr Karmy, feel free to email us at [email protected]. Follow our social media: Instagram https://www.instagram.com/karmychronicpain?igsh=cHZycXdzeGhqN2Zn Facebook https://www.facebook.com/profile.php?id=615502373…
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Episode 16: Journavx - Nerve Block in a Pill! A Game-Changer for Pain Management or Just Hype?
10:11
10:11
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10:11In this episode, Dr. Karmy will review everything known so far about the newest and first-in-class non-addictive pain medication, Journavx. Follow our social media: Instagram https://www.instagram.com/karmychronicpain?igsh=cHZycXdzeGhqN2Zn Facebook https://www.facebook.com/profile.php?id=61550237320641&mibextid=dGKdO6 Send us a text with your thoug…
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Episode 15: Fibromyalgia - A Basic Approach to Management
19:20
19:20
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19:20This episode describes Dr. Karmy's approach to patients with fibromyalgia. He delves into what are the treatments he finds the most helpful and the pros and cons of each approach. If you have any questions for Dr Karmy, feel free to email us at [email protected]. Follow our social media: Instagram https://www.instagram.com/karmychronicpain…
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Episode 14: Why Won't My Earache Go Away? One Patient's Experience of Trying to Deal with a Rare Chronic Pain Disorder
52:52
52:52
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52:52Most of us have experience with earaches, either in our children or sometimes through personal experience. Although the pain is severe, it does resolve in a few days. What if the pain never went away? Join Dr Karmy for an interview with a clinic patient who has a very unusual chronic pain condition. In this interview, we discuss how our patient fou…
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Episode 13: Cervicogenic Headaches, Nerve Blocks and the Birth of Chronic Pain Medicine in Ontario Part 2
27:29
27:29
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27:29In the second part of the interview with Dr.Howard Jacobs, one of the fathers of pain management in Ontario, we discuss how the medical discipline of Chronic Pain developed in the last 20 years and the challenges facing it in the future. Listen to Episode 10-Part 1 of this interview to discover how Dr. Howard Jacobs revolutionized chronic pain mana…
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Episode 12: Regenerative Medicine from a Biotech Industry Perspective
38:40
38:40
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38:40Join Dr. Karmy for an in-depth interview with Dr. Jennifer Woodell-May who was instrumental in the development of the newest treatment for osteoarthritis. In this episode, Dr. Woodell-May answers the following questions: 1. How are new autologous and regenerative treatments created? 2. What are some of the obstacles to creating new autologous, cell…
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Episode 11: Acorn Biolabs and the Future of Stem Cell Treatments in Canada
57:47
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57:47Join Dr. Karmy for an interview with Acorn Biolabs CEO, Dr. Taylor, where they discuss the unique approach his company is taking to stem cell treatments. The wide ranging discussion will also cover his vision for the future of his company and how it fits into the broader field of regenerative medicine. Acorn Biolabs: Acorn Biolabs - Personalized Re…
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Episode 10: Cervicogenic Headaches, Nerve Blocks and the Birth of Chronic Pain Medicine in Ontario Part 1
36:47
36:47
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36:47There was a time in Ontario when chronic pain patients who didn’t respond to physiotherapy or surgery were often given only basic advice to exercise or referred to a psychologist or psychiatrist to ensure they weren’t suffering from depression. But then, Dr. Peter Rothbart changed everything by founding the first community-based chronic pain clinic…
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Episode 9: Can Cortisone Injections Really Help with Joint Pain? Debunking Myths and Clearing Up Misconceptions
16:19
16:19
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16:19In this episode, Dr. Karmy dives into the facts and misconceptions surrounding cortisone injections. Often misunderstood, these powerful anti-inflammatory treatments can offer significant relief for joint pain, tendon issues, and nerve inflammation. Join Dr Karmy as he explores when cortisone is most effective, its potential risks, and why it may n…
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Episode 8: Botox Injections for Chronic Migraines - It's Not Just for Wrinkles
16:11
16:11
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16:11Botox is best known as a cosmetic treatment, however in addition to cosmetic uses it has a wide range of medical applications. In this episode, Dr Karmy explores the role of Botox therapeutic injections in managing chronic migraines—a condition that impacts millions worldwide and is often resistant to traditional medications. Join Dr. Karmy as he b…
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Episode 7: Radiofrequency Ablation - A Novel OHIP Covered Treatment for Back Pain
19:21
19:21
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19:21In this episode, Dr Karmy explores the world of radiofrequency ablation—a novel, OHIP-covered treatment for chronic back pain. He goes over the differences between radiofrequency ablation, pulsed radiofrequency, and cooled radiofrequency ablation, uncovering how each technique works and when they should be considered viable treatment options. Join …
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Episode 6: Neurobiology of Pain - Exploring Neuropeptides
41:35
41:35
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41:35In this episode, Dr Karmy is joined by Dr. James Henry, a pioneering expert in the field, where they dive deep into the neurobiology of pain. Trained at McGill University and with a distinguished career spanning Western University and McMaster's Michael De Groote Pain Center, Dr. Henry brings a wealth of knowledge on the role of neuropeptides in ch…
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Episode 5: Is the nSTRIDE Injection the Future of Knee Osteoarthritis Treatment?
30:08
30:08
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30:08In this episode, Dr Karmy will take an in-depth look at the newest treatment for osteoarthritis—the nSTRIDE Autologous Protein Solution (APS) kit. Like Platelet Rich Plasma (PRP), this treatment is made from the patient's own blood. How does it compare to PRP? Is it worth trying? Dr. Karmy will not only explain the science behind nSTRIDE from exist…
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Episode 4: Regenerative Medicine in Pain Management - Is it a medical breakthrough or a scam?
41:57
41:57
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41:57An in-depth discussion of the most popular regenerative medicine approaches to chronic pain management in Ontario. Approaches discussed include Prolotherapy, Prolozone, nSTRIDE, PRP, and autologous stem cell injections. The pros and cons of each approach is discussed to help you decide whether or not you want to dip your toes into one of these appr…
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Episode 3: Nerve Blocks in Chronic Pain Management - How Nerve Blocks Can Help Manage Your Pain?
26:03
26:03
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26:03Nerve blocks are the most common procedure performed for chronic pain management in Ontario. Over 55,000 patients receive this treatment every year. Yet despite the widespread use of this procedure, there is some controversy about this approach. Nerve blocks happen to be one of the first procedures Dr. Grigory Karmy learned to perform. In this epis…
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Episode 2: Infusions in Chronic Pain Management: Psychedelics, Lidocaine, Vitamins - Which Infusion is Right for You?
11:01
11:01
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11:01Dr. Grigory Karmy offers a comprehensive analysis of the therapeutic potential of ketamine and lidocaine infusions in managing various medical conditions, from chronic pain to treatment-resistant depression. He elucidates how these infusions work, their mechanisms of action, and the scientific evidence supporting their use. Tune in to learn about k…
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Episode 1: Should Opioids be a Part of Your Treatment Regimen for Chronic Pain in 2024?
17:06
17:06
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17:06This episode explores the current approach to opioids in Ontario from the perspective of a clinician with over 20 years of experience in chronic pain management. The segment takes a close look at how the approach to opioids has evolved over the past two decades. Despite their longstanding presence in pain management, opioids remain shrouded in conf…
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