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The Phage Therapy Today is the pod dedicated to leaders in the phage therapy industry. We bring you insights into current advancements and challenges in this exciting sector from academia, financial, regulatory, manufacturing and entrepreneurial perspectives. Each episode features accomplished guests serving various roles in developing our bacteriophage-evolved community. If you are a believer in the future shaped by phage therapy and want to share you exciting work with our community, email ...
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PhageLine

Planomicrobium massiliensis

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PhageLine unpacks the science of bacteriophages, one paper at a time. From groundbreaking studies to surprising discoveries, we translate complex research into engaging conversations. Whether you are steeped in microbiology or just discovering the fascinating world of phages, PhageLine delivers a unique perspective on the science behind these bacterial predators. PhageLine is on BlueSky and TikTok. Follow us never to miss anything again. This podcast is generated using artificial intelligenc ...
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Editors at The Lancet Microbe, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy. A monthly audio companion to this open access journal, this podcast covers a broad range of topics, from using probiotics to reduce Staphylococcus aureus, to phage therapy and monitoring antimicrobial resistance using faecal metagenomes, and more.
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This Week in Microbiology

Vincent Racaniello

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Monthly
 
This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.
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Data in Biotech is a fortnightly podcast exploring how companies leverage data to drive innovation in life sciences. Every two weeks, Ross Katz, Principal and Data Science Lead at CorrDyn, sits down with an expert from the world of biotechnology to understand how they use data science to solve technical challenges, streamline operations, and further innovation in their business. You can learn more about CorrDyn - an enterprise data specialist that enables excellent companies to make smarter ...
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We are delighted to present "Making science work for health", the PHG Foundation podcast that explains the most promising developments in science and their implications for healthcare. In each episode, host Ofori Canacoo discusses with a PHG Foundation policy analyst, the underpinning science, the ambitions for improving population health and the impact it could have on patients, on society and on the people delivering your healthcare.
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Everybody Hates Me: Let's Talk About Stigma

Dr. Carmen Logie, Canada Research Chair

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Hosted by Dr. Carmen Logie, Canada Research Chair in Global Health Equity & Social Justice with Marginalized Populations, and Professor at the University of Toronto's Factor-Inwentash Faculty of Social Work. Supported by the Canada Foundation for Innovation (CFI). This podcast invites a range of weekly guests to talk about all different kinds of stigma. Why does it matter? What does it look like? What can we do about it?Thank you for listening! Follow us on Twitter (@let_stigma) and Instagra ...
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ARMOR on the Air

ARMOR on the Air

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ARMOR on the Air is a student-led podcast based out of the University of Colorado Boulder. We discuss the antimicrobial resistance crisis and what we as members of the public can do to help! Join our hosts, undergraduates Ezra and Andy, as we learn more about superbugs and how to stop them! ARMOR is an outreach organization at CU Boulder. We promote safe and responsible use of antibiotics, support research into new antibiotics, and encourage the public to take steps in their daily lives to l ...
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show series
 
Hello and welcome to PhageLine - your line to everything phage. This week, we will discuss personalized inhaled bacteriophage therapy for treating multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis by talking about a recent publication by Chan et al in Nature Medicine. Have fun! This episode was generated using artificial intelligence. A…
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Antimicrobial resistance is a rising global threat. When these become ineffective, infections can become difficult or impossible to treat, leading to an increase in the spread and severity of disease. In a new study, published in Nature Medicine, a team of researchers at the Center for Phage Biology and Therapy at Yale discovered a novel approach t…
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Phage therapy is stepping into the spotlight as antibiotic resistance rises - and Jessica Sacher is helping lead the charge. In this episode, Ross Katz speaks with Jessica, Co-Founder of Phage Directory and Staff Scientist at Stanford, about sourcing phages, operationalizing therapy, and predicting efficacy through data. This conversation explores …
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In this episode of Data in Biotech, host Ross Katz sits down with Scott Lipnick, Co-Founder and President of Etiome, to explore how preemptive medicine is changing the way biotech approaches therapeutic modeling and intervention. Discover how Etiome’s recently launched, AI-driven platform is built to detect disease earlier, identify precise biomark…
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May is Mental Health Awareness Month and on today’s show, we are going to look at four mental health issues -anxiety, adult ADHD, PTSD, and depression. Joining me today to discuss these issues and his personal story is author & social psychologist, Jamie Hughes. Managing Mental Health Watch the video version on YouTube…
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Hello and welcome to PhageLine - your line to everything phage. This week, we will discuss the in vitro genomic characterization and pre-clinical evaluation of a new thermostable lytic Obolenskvirus phage formulated as a hydrogel against carbapenem-resistant Acinetobacter baumannii by discussing a recent paper by Sherif et al. in Scientific Reports…
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TWiM explains a study of the unique and extreme microbial and chemical environment on the International Space Station, and the connection between the gut microbiome and pain in fibromyalgia. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and us…
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A complex field, host genomics research aims to identify genetic variants that might explain different individual responses to an infectious disease. A companion piece to our report, Host genomics: lessons for infectious disease, policy analyst and lead author of the report, Heather Turner, discusses the findings of the report and why host genomics…
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The warm weather of summer is upon us, people will spend more time doing outdoor activities, as will potentially dangerous pathogens carrying critters like mosquitoes and ticks. My guest today will discuss the risks mosquitoes and ticks pose to Americans across the country. In addition, she’ll explain how the public can best protect ourselves and f…
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In this episode of Data in Biotech, host Ross Katz speaks with Patrick Torbey, CEO and Co-Founder of Neoplants, about using genetic engineering and microbiome innovation to tackle indoor air pollution. Patrick explains how Neoplants is turning everyday houseplants into powerful air purifiers using synthetic biology, offering insights into VOC degra…
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Hello and welcome to PhageLine - your line to everything phage. This week, we will discuss the effects of Phage–phage competition and biofilms on interactions between two virulent bacteriophages and Pseudomonas aeruginosa, which were recently published by Bürkle et al. in ISME. Have fun! This episode was generated using artificial intelligence. An …
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Hello and welcome to PhageLine - your line to everything phage. This week, we will discuss PhageDPO, a machine-learning-based computational framework for identifying phage depolymerases, recently published by Viera et al. in Elsevier's Computers in Biology and Medicine. Have fun! This episode was generated using artificial intelligence. An infectio…
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Hello and welcome to PhageLine - your line to everything phage. This week, we will focus on the differences in phage recognition and immunogenicity in humans unraveled in a recent paper by Le et al. in the European Journal of Immunology. Have fun! This episode was generated using artificial intelligence. An infectious disease researcher reviewed th…
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TWiM describes isolation of a novel bacterial species isolated from the China Space Station, and how a chemical radar allows bacteria to detect and kill predators. Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin. Guest Mark O. Martin. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with p…
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Tanya Brigden discusses the ethical implications and regulatory challenges that should be considered in the innovative area of genome editing. In recent years, the potential of somatic genome editing has elicited both excitement and caution among researchers, clinicians, patients, and ethicists. Welcome back to Making science work for health, the P…
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This podcast invited Dr. Mike Lang and Kristy Wolfe, digital storytelling experts at Common Language Digital Storytelling to reflect on the power of digital storytelling and stigma reduction. Carmen met Mike and Kristy at the First International Digital Storytelling Festival in Greece in 2024 where she was blown away by their powerful stories acros…
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How do you drug the undruggable? In this episode of Data in Biotech, Ross Katz sits down with Will Fondrie, Head of Data Science and Engineering at Talus Bio, to explore how machine learning, mass spectrometry, and innovative computational models are transforming drug discovery. Learn how Talus Bio is targeting transcription factors—once considered…
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Hello and welcome to PhageLine - your line to everything phage. This week, we will focus on optimizing phage engineering through an accelerated evolution platform by discussing a recent paper by Favor et al. from Nextbiotics Inc. in Scientific Reports. Have fun! This episode was generated using artificial intelligence. An infectious disease researc…
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TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for …
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A developing area in synthetic biology, electrogenetics is hoped to become a new avenue in precision medicine, helping with the treatment of certain chronic diseases. Chaitanya Erady talks about what electrogenetics is and the ambitions for its use. Welcome back to Making science work for health, the PHG Foundation podcast that explains the most pr…
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Hello and welcome to PhageLine - your line to everything phage. This week, we will focus on 3D models for mimicking biofilms in diabetic foot ulcers for phage therapy. German researchers from Frankfurt and Jena recently reviewed this topic. The phage lab at the University Hospital Frankfurt was recently featured in Capsid & Tail for having built it…
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In this episode of the Data and Biotech Podcast, host Ross Katz sits down with Dr. Jonathan Usuka to discuss Usuka’s extensive background in bioinformatics and genomics, leading to his current role as CEO of Sapient. The conversation dives into the importance of deep molecular characterization of diseases, the role of proteomics and metabolomics in…
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On today’s show, I want to take a look at three news stories about rabies recently and have my expert guest break them down. I want to look at the fatal case in a organ transplant recipient, catching rabies from cow’s milk and the upsurge in positive raccoons in Quebec. Joining me today is Charles E. Rupprecht, VMD, MS, PhD. Dr Rupprecht is the CEO…
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Rebecca Barksby of The Lancet Microbe speaks to Dr Anastasia Theodosiou about performing a controlled human infection study in pregnant women investigating mother-to-infant transmission of Neisseria lactamica. Read the full article: https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(24)00254-4/fulltext?dgcid=buzzsprout_icw_podcast_gene…
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Hello and welcome to PhageLine - your line to everything phage. This week, we will focus on the mechanisms of tailed bacteriophage adsorption. For that, we will discuss a review from Storms and Sauvageau from the Department of Chemical and Materials Engineering at the University of Alberta, which was published in Elsevier's "Virology" in 2015. Have…
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Welcome to PhageLine. This week, we will focus on the applications of bacteriophage-derived endolysins for foodborne bacterial pathogens and food safety, a topic recently reviewed by Kahn et al. from Shenzhen University in Frontiers of Microbiology. Have fun! #medicine #biology #bacteriophages #infection #amr #basicresearch #food #foodsafety This e…
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How can AI improve clinical trials and accelerate drug development? In this episode of Data in Biotech, Ross Katz sits down with Patrick Leung, CTO of Faro Health, to explore how AI-driven tools are reshaping clinical trial design. Patrick shares insights into document generation, patient burden analysis, and AI governance in biotech. Learn how Far…
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TWiM explains Pasteur’s relentless hunt for microbes in the air, and how bacteria hunt for prey by ixotrophy - using grappling hooks! Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Pa…
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Welcome to PhageLine. This week, we will focus on CRISPRi-ART, a method for functional genomics of diverse bacteriophages published by Benjamin Adler et al. from the University of California in Nature Microbiology at the end of February. Have fun! #medicine #biology #bacteriophages #infection #amr #basicresearch #CRISPR #genomics #cas13 This episod…
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Type 1 diabetes is a complex disease affecting millions of people across the world. Though insulin has been discovered as a treatment for patients, research is still being done to find additional and alternative methods to treat and perhaps cure type 1 diabetes. Hayley Wilson discusses how gene therapy is being used as one potential method of treat…
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Welcome to PhageLine. This week we will examine the synergistic action of mucoactive drugs and phages against Pseudomonas aeruginosa and Klebsiella pneumoniae. Have fun! #medicine #biology #bacteriophages #cough #amb #nac #infection #amr This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents…
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Today I want to take a look at the Basic Reproduction Number, or R0 (r-naught). We saw this term become more commonplace in the news and other talk during the COVID-19 pandemic. What is R0 and what does it mean? How do public health officials come up with this number? What are the limitations? And how is it used in everyday public health? Joining m…
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In this episode of Data In Biotech, Ross Katz interviews Naren Tallapragada, CEO and Co-founder of Tessel Bio, about his background in electrical engineering and physics and how personal circumstances led to him pivoting his focus to enter biotech and start Tessel Bio. Naren breaks down Tessel Bio’s unique approach to drug discovery, which involves…
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Welcome to PhageLine. This week we will focus on the molecular basis of foreign DNA recognition by the BREX anti-phage immunity system. Have fun! This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode.#medicine #biology #bacteriophages #bacteria #defense #infection #amr…
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TWiM describes Shigella infection is facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swa…
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Elena Dalla Vecchia of The Lancet Microbe speaks to Susan Meiring, Vanessa Quan, and Nelesh Govender about bloodstream infections in neonates at lower-tier South African hospitals. Read the full paper, Pathogen aetiology and risk factors for death among neonates with bloodstream infections at lower-tier South African hospitals: a cross-sectional st…
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Welcome to PhageLine. This week we will focus on a bacteriophage-based method for infection and thrombosis prevention using a phage-immobilized, nitric oxide-releasing surface. Have fun! This episode was generated using artificial intelligence. An infectious disease researcher reviewed the contents of the episode. #medicine #biology #bacteriophages…
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In this episode of the Data and Biotech Podcast, host Ross Katz sits down with Alexander Junge, Co-Founder and CTO of amass, to break down how AI is reshaping scientific research in life sciences. Alex walks us through how his platform is creating professional tools for researchers, biotech companies, and venture firms to navigate the (rapidly!) gr…
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Welcome to PhageLine. This week we will focus on using specific phage proteins called endolysins instead of whole phages to fight bacteria by discussing the in vitro and in vivo efficacy of an engineered endolysin targeting Gram-negative pathogens. Have fun! This episode was generated using artificial intelligence. An infectious disease researcher …
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In this episode of Data in Biotech, Ross sits down with Dipen Sangurdekar, VP of Data Sciences at KSQ Therapeutics, to discuss the role of data-driven approaches in therapeutic design and development. The conversation explores the intersection of computational biology, machine learning, and bioinformatics in advancing personalized medicine and impr…
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Welcome to PhageLine. In this week's episode, we will focus on one of the biggest phage papers in 2024: a multicentre, multinational, retrospective observational study of personalized bacteriophage therapy outcomes for 100 consecutive cases headed by Jean-Paul Pirnay and Sarah Djebara. This episode was generated using artificial intelligence. An in…
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TWiM explains the remarkable abilities of bacterial ice nucleating proteins to promote freezing of water, and cryoprotective proteins produced by worm microbiomes that prevent freezing. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees…
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If you’re in the field of bacteriophage therapy or looking to break into the space, you won’t want to miss the 7th Bacteriophage Therapy Summit happening next month in Boston! 🌍💡 This is the place to be if you're passionate about combating antibiotic resistance and advancing the next generation of phage-based treatments. 💬 Want to connect with top …
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Welcome to PhageLine. In this week's episode, we will discuss bacteriophage-based biosensor technology by discussing the review Bacteriophage-based biosensors technology: Materials, fabrications, efficiencies and shortcomings (Haq et al., 2025 Biotechnology Reports). This episode was generated using artificial intelligence. An infectious disease re…
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Welcome to PhageLine. In this week's episode, we will discuss the isolation and characterization of phages with clinical relevance from environmental sources. This week's papers are: Isolation of a lytic bacteriophage against extensively drug-resistant Acinetobacter baumannii infections and its dramatic effect in rat model of burn infection (Ghazna…
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TWiM explores the discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson. Guest Mark O. Martin. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a …
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This week on Data in Biotech, we welcome Timothy Jenkins, the Head of Data Science and Associate Professor at DTU Bioengineering, a leading scientific community dedicated to advancing areas of biotechnology, food technology, and health through innovative teaching and research. Timothy starts the conversation by walking us through his background and…
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Hello and welcome to PhageLine - your line to everything phage. This podcast is where we discuss exciting research papers on bacteriophages once a week. To get started let's get a general overview of the topic by talking through a review by Kortright et al. from 2019 (last author Paul E. Turner), titled "Phage Therapy: A Renewed Approach to Combat …
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TWiM reveals that record high atmospheric methane growth has been driven by microbes, and the cecum as an adaptive niche for Salmonella typhi. Hosts: Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed …
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In this episode, Ross Katz sits down with Fred Manby, Co-Founder and Chief Technology Officer of Iambic Therapeutics, to explore how cutting-edge AI technologies are reshaping the landscape of drug discovery. From building advanced machine learning platforms to designing user-friendly interfaces for scientists, Fred shares insights into the company…
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