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CCO Oncology Podcast

Clinical Care Options

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Updates on new data and best practices in the care of patients with cancer across a wide variety of solid tumors and hematologic malignancies from Clinical Care Options. Gain practical clinical insights and strategies and earn CME/CE credit for selected episodes.
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The Neuroendocrine Cancer Foundation Podcast is a monthly series where we interview neuroendocrine cancer experts on various NET topics. Each expert will answer the top 10 FAQs in their area of expertise. Whether a listener is newly diagnosed, a longtime NET survivor, or a family member or loved one, the Neuroendocrine Cancer Foundation Podcast serves as a tool to help anyone better understand neuroendocrine cancer. For more information, visit www.ncf.net/podcast.
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Blood Cancer Talks

Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff

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This is a podcast on latest advances in the understanding and management of blood cancers. Here, we will bring a wide range of experts within hematologic malignancies to discuss various topics in depth. Host: Raj Chakraborty, MD from Columbia University, New York, Ashwin Kishtagari, MD, from Vanderbilt University, Nashville, and Edward Cliff, MD, from Harvard University, Boston Tweet your suggestions and feedback to @rajshekharucms @AshKishtagari @Eddie_Cliff @BloodCancerTalk
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The Pediatric and Developmental Pathology Podcast

Pediatric and Developmental Pathology

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Featuring the authors and articles in the journal Pediatric and Developmental Pathology (https://journals.sagepub.com/home/pdp), the official journal of the Society for Pediatric Pathology (https://www.spponline.org/) and the Paediatric Pathology Society (https://www.paedpath.org/).
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Nursology

Joe Jackson

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A podcast by nurses and nursing students, for nurses and nursing students! We aim to add value to your nursing career, whether that be as a student, a new grad, or a practiced nurse!
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Featuring one-on-one discussions with leading oncology investigators, this series assists clinicians with the formulation of up-to-date clinical management strategies so that they can provide optimal care for patients with melanoma and nonmelanoma skin cancer.
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USMLE Step 2 CK Plus

Abdillahi Omar, M.D.

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This book and subsequent audio companion reflect what I would have wanted when I was studying for the USMLE Step 2 CK exam. One of the major hurdles I faced while studying for my exam was the lack of a single reference resource similar to what existed for the USMLE Step 1 exam at the time of writing this book. This meant I had to use multiple resources which presented information in different formats and with different points of emphasis, resulting in a disorganized study approach. Despite m ...
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In this episode of the Pediatric and Developmental Pathology, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Ülgen Çeltik of the Department of Pediatric Surgery, Ege University Faculty of Medicine in Izmir, Turkey. Hear about her article in Pediatric and Developmental Pathology: Is Conservative Management of Noninvas…
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In this episode of Blood Cancer Talks, hosts Eddie, Ashwin, and Raj welcome two distinguished experts to explore the cutting-edge field of circulating tumor DNA (ctDNA) in B-cell lymphomas. Dr. David Russler-Germain, a lymphoma clinician from Siteman Cancer Centre at Washington University in St. Louis, returns as a familiar voice to the podcast aud…
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Substance-Related and Addictive Disorders Alcohol Use Disorder Definition/Overview Clinical Presentation Labs, Studies, and Physical Exam Findings Treatment Key Differentiators Test Alert Opioid Use Disorder Definition/Overview Clinical Presentation Labs, Studies, and Physical Exam Findings Treatment Key Differentiators Test Alert Stimulant Use Dis…
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Personality Disorders Definition/Overview Clusters High-Yield Management Principles Cluster A: Odd / Eccentric (Mad) Paranoid Personality Disorder Definition/Overview Clinical Presentation Labs, Studies, and Physical Exam Findings Treatment Key Differentiators Test Alert Schizoid Personality Disorder Definition/Overview Clinical Presentation Labs, …
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In this episode, Dr Christopher Flowers and Dr John Allan discuss their experience with the use of CD20xCD3 bispecific antibodies in the treatment of patients with relapsed/refractory follicular lymphoma. They also their thoughts on key ongoing clinical trials with bispecific antibodies that they are excited about for their potential to change the …
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Listen in as Zev A. Wainberg, MD; Paul E. Oberstein, MD; and Mark O’Hara, MD, discuss the evolving treatment landscape for metastatic pancreatic cancer, including: How patients often present with disease-related symptoms Treatment selection considerations for the first-line and second-line setting How to approach palliative care discussions with pa…
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In this episode, Dr Brad Kahl and Dr Noopur Raje discuss the recent advances and emerging data for CAR T-cell therapy in lymphomas and multiple myeloma including the latest evidence from long-term clinical trial follow-up and real-world data, plus new data with CAR T-cell therapies in new lymphoma settings and novel CAR T-cell therapies currently u…
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Attention-Deficit/Hyperactivity Disorder (ADHD) Neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. Clinical Presentation Inattention (≥6 symptoms if ≤16; ≥5 if ≥17): Hyperactivity/Impulsivity (≥6 symptoms if ≤16; ≥5 if ≥17): Functional impairment required (academic, social, occupational). Labs, Studies, and Ph…
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In this episode, Drs William J. Gradishar, Heather McArthur, and Joanne Mortimer address audience questions from a recent live event on the use of CDK4/6 inhibitors in patients with early and metastatic breast cancer, including: Genomic testing options for assessing risk of recurrence Adjuvant treatment duration and holidays with CDK4/6 inhibitors …
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In this episode of Blood Cancer Talks, we have Dr. Adrian Minson from the Peter MacCallum Cancer Centre to discuss the latest developments in lymphoma presented at the recent EHA and ICML meetings in June 2025. The episode focuses primarily on the emerging role of bispecific antibodies in various combinations and treatment settings for diffuse larg…
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Bipolar and Related Disorders Chronic mood disorder with episodes of mania/hypomania and depression.Onset typically late teens–20s. Equal in men/women. Strong genetic predisposition. Clinical Presentation Bipolar I Disorder Bipolar II Disorder Cyclothymic Disorder Hallmark exam clues Labs, Studies, and Physical Exam Findings Treatment First-line (m…
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In this episode, Dr. Daniel Morgensztern and Dr. Jonathan Strosberg discuss the emerging role of DLL3-targeted agents in the management of extrapulmonary neuroendocrine carcinomas, including: The clinical implications of using DLL3 as a therapeutic target The impact of emerging DLL3-targeted therapies on evolving treatment paradigms How to incorpor…
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In this episode of the Pediatric and Developmental Pathology, our hosts Drs. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Miss. Tania Marsden of the NHMRC Centre of Research Excellence in Stillbirth, Mater Research Institute – University of Queensland, Brisbane, Australia; Professor Yee Khong of SA Pathology, Women’s and Children’s …
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Generalized Anxiety Disorder (GAD) Clinical Presentation Labs, Studies & Imaging Treatment & Management Panic Disorder Clinical Presentation Labs, Studies & Imaging Treatment & Management Phobias Clinical Presentation Labs, Studies & Imaging Treatment & Management Obsessive-Compulsive Disorder (OCD) Clinical Presentation Labs, Studies & Imaging Tre…
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In this episode, listen to Kelly Romo, PharmD, BCOP; and Shauna Kraft, PharmD, BCOP, share their takeaways from a live webinar on available emerging subcutaneous immunotherapy options for patients with cancer including: Basic mechanism of action and role of hyaluronidase in subcutaneous immunotherapy formulation and available dosing/schedules Avail…
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In this podcast, Max S. Topp, MD, and Pier Luigi Zinzani, MD, PhD, explore the current and future implications of some of their top choices of studies in lymphomas and ALL presented at the EHA and ICML 2025 meetings. Program Abstracts: POLARGO: Rituximab, Gemcitabine and Oxaliplatin ± Polatuzumab Vedotin for R/R DLBCL ECHO: Rituximab-Bendamustine ±…
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In this episode, Kevin Kalinsky, MD, MS, FASCO, and Sara M. Tolaney, MD, MPH, discuss the most clinically relevant data in breast cancer presented at the 2025 ASCO Annual Meeting, including: DESTINY-Breast09: phase III trial of trastuzumab deruxtecan with or without pertuzumab vs THP as first-line treatment of HER2-positive advanced/metastatic brea…
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In this episode, listen to Laura M. Spring, MD; and Shipra Gandhi, MD, MS, share their takeaways from a large educational program on available and emerging first-line treatment options for patients with HER2-positive mBC: Emerging new data from the phase IIII DESTINY-Breast09 trial of first-line treatment with trastuzumab deruxtecan ± pertuzumab vs…
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Dr Rashmi Chugh from Rogel Comprehensive Cancer Center in Ann Arbor, Michigan, and Dr Mrinal Gounder from Memorial Sloan Kettering Cancer Center in New York, New York, summarize major clinical findings presented at the 2025 ASCO Annual Meeting for patients with soft tissue sarcoma and other connective tissue neoplasms. CME information and select pu…
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In this episode, we discuss the management of follicular lymphoma with Dr. Gilles Salles from Memorial Sloan Kettering Cancer Center. Here are the articles we discussed: 1. Relevance of Bone Marrow Biopsy in Follicular Lymphoma: https://pubmed.ncbi.nlm.nih.gov/35787017/ 2. TROG 99.03 (RCT of Systemic Therapy after Involved-Field Radiotherapy in Pat…
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In this episode, Eunice Wang, MD and Eytan Stein, MD explore the latest key clinical updates on menin inhibitors in AML. This episode unpacks evolving treatment strategies and what these developments mean for patient care. Presenters: Eytan M. Stein, MD Chief, Leukemia Service Director, Program for Drug Development in Leukemia Associate Attending P…
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In this episode, James Davis, PharmD, BCOP and Victoria Nachar, PharmD, BCOP summarize the latest key clinical updates on BTK inhibitors in CLL based on data recently presented at the annual ASCO and EHA meetings, including: The randomized phase III FLAIR trial The randomized phase III SEQUOIA trial The randomized phase III BRUIN CLL-321 trial Pres…
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Cauda Equina Syndrome • Neurosurgical emergency due to compression of cauda equina nerve roots, usually from disc herniation, tumor, or trauma Clinical Presentation Labs, Studies, and Physical Exam Findings Treatment Key Differentiators Epidural Abscess • • Spinal epidural infection commonly caused by Staphylococcus aureus Clinical Presentation Lab…
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ABOUT THIS EPISODE Neuroendocrine cancer care typically involves a multidisciplinary team which sometimes involves an Advanced Practice Provider (APP). In this episode, Moffitt Physician Assistant Tiffany Valone clarifies the role of an APP in neuroendocrine cancer. TOP TEN QUESTIONS What is a NP/PA/APP? -Are you a doctor? How are you different fro…
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In this episode, Joseph W. Franses, MD, PhD; Neehar Parikh, MD, MS; and Mark Yarchoan, MD, share their thoughts on incorporating immune checkpoint inhibitors into the care of patients with HCC including: Clinical Considerations for Selecting First-line Immunotherapy Combinations for Metastatic HCC Overview of the Latest Data for the Combination of …
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In this episode, Jonathan W. Friedberg, MD; Alex F. Herrera, MD; and Kara Kelly, MD, discuss the latest frontline treatment options for advanced Hodgkin lymphoma (HL) and approaches to personalizing treatment for the general patient population, older patients, and pediatric patients. This podcast was adapted from a live presentation held in May 202…
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In this episode of the Pediatric and Developmental Pathology, our hosts Drs. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Haiying Chen, Pediatric Pathologist at The Hospital for Sick Children in Toronto, Dr. Gino Sommers, Chief of Pediatric Pathology at The Hospital for Sick Children in Toronto and Professor and Vice Chair of Pa…
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In this episode, Jesus Berdeja, MD; Amrita Krishnan, MD, FACP; and Sagar Lonial, MD, FACP, discuss key topics with CELMoD therapy for multiple myeloma, including: Mechanistic differences between CELMoDs and IMiDs Emerging data with CELMoDs and their potential therapeutic roles across the disease continuum of multiple myeloma The clinical implicatio…
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One of the key aspects of one’s neuroendocrine cancer care is building your medical team, which typically includes a medical oncologist. In this episode, Medical Oncologist Dr. Sandy Kotiah from Mercy Medical Center in Baltimore expounds on the role of a medical oncologist. She sheds light on the first appointment, communication, and care coordinat…
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In this episode, we took a deep dive intro the landscape of menin inhibitors in AML with Dr. Eytan Stein from MSKCC. Here are the key trials and studies we discussed: ELN 2022 AML Classification https://ashpublications.org/blood/article/140/12/1345/485817/Diagnosis-and-management-of-AML-in-adults-2022 Predictors of outcomes in adults with AML and K…
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When in one’s neuroendocrine cancer journey might a clinical trial be considered? What factors influence treatment decisions, including whether to pursue a clinical trial? Dr. Alexandria Phan, medical oncologist at the Medical College of Wisconsin, offers thoughtful guidance on when and how clinical trials fit into the neuroendocrine cancer journey…
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In this episode of the Pediatric and Developmental Pathology, our hosts Drs. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Raquel Ilgenfritz of Hospital CUF Descobertas in Lisbon, Portugal as well as Unidade Local de Saúde Almada-Seixal, Almada, Portugal, and Dr. Ana Lai of Unidade Local de Saúde de Coimbra, Coimbra, Portugal. He…
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In this podcast episode, Sara A. Hurvitz, MD, FACP, La-Urshalar B. Brock, FNP-BC, CNM, and Jordan Hill, PharmD, BCOP, discuss the important role of the multidisciplinary team in achieving comprehensive and individualized care of patients with HR-positive/HER2-negative metastatic breast cancer and preexisting comorbidities, including: Key Comorbidit…
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In this episode, we discuss the recent proceedings at the FDA ODAC meeting on AQUILA trial in smoldering myeloma and STRAGLO in R/R DLBCL, and provide an update to our audience on some of the clinically relevant data presented from those trials, along with insights from the panelists. Here is the link to the webpage with FDA briefing documents and …
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In this episode, Catherine Fahey, MD, PhD; Alexandra Leary, MD, PhD; Funda Meric-Bernstam, MD; and Zev A. Wainberg, MD, discuss the evolving safety considerations and future directions of HER2-targeted antibody–drug conjugates (ADCs) across genitourinary, gastrointestinal, and gynecologic cancers. Toxicity Profiles of HER2-Targeted ADCs: Common and…
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In this episode of the Pediatric and Developmental Pathology, our hosts Drs. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Saeeda Almarzooqi, Assistant Dean for Medical Education and Professor of Pathology at United Arab Emirates University, about her article in Pediatric and Developmental Pathology: Hereditary Multiple Intestina…
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In this episode, we discussed the management of systemic mastocytosis with Dr. Daniel DeAngelo from the Dana Farber Cancer Institute. Here are the key studies we discussed: Midostaurin https://www.nejm.org/doi/10.1056/NEJMoa1513098?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov Avapritinib EXLPORER study: …
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In this episode, Catherine Fahey, MD, PhD; Alexandra Leary, MD, PhD; Funda Meric-Bernstam, MD; and Zev A. Wainberg, MD, explore the mechanisms of HER2-targeted antibody–drug conjugates (ADCs) and emerging clinical data with these agents across genitourinary, gastrointestinal, and gynecologic cancers. Mechanisms of action of ADCs: how ADCs selective…
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Last time, we covered the detailed medical content on infectious neurologic disorders. (If you missed it, you can find it here: physicianassistantexamreview.com/130) This week is about action. We’re taking everything you learned and making it stick by applying it to questions, clues, and decision-making strategies you’ll need on test day. We’ll wor…
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In this episode, hear Lauren Byers, MD and Christine Hann, MD share their insights on the latest data regarding new therapies targeting B7-H3 in small cell lung cancer including: Rationale for targeting B7-H3 Overview of the structure of antibody-drug conjugates (ADCs) Results from the phase I/II IDeate-PanTumor01 trial of ifinatamab deruxtecan (I-…
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In this episode, Zev A. Wainberg, MD; Funda Meric-Bernstam, MD; Alexandra Leary, MD, PhD; and Catherine Fahey, MD, PhD, explore testing for HER2 alterations and the incidence of HER2-positive disease in the treatment of genitourinary, gastrointestinal, and gynecologic malignancies. HER2 Testing in Advanced Cancers: Recommendations for when and how …
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Encephalitis Inflammation of the brain parenchyma, often viral in origin, presenting with altered mental status, seizures, and focal neurologic deficits. Can be life-threatening. Viral Encephalitis (Most Common) HSV-1 Encephalitis Clinical Presentation: Labs & Imaging: Treatment: Arboviral Encephalitis Clinical Presentation: Diagnosis: Treatment: M…
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