Best Ms Sinclair Podcasts (2025)

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The Science of Muscle, Protein, and Longevity: Insights from Dr. Layne Norton 1:19:20

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13d ago1:19:20

1:19:20

In this episode of Longevity By Design, Dr. Layne Norton, Founder of BioLayne and Carbon app, joins Gil Blander to discuss optimizing nutrition and fitness for a longer, healthier life. Layne emphasizes the importance of prioritizing scientific evidence over popular narratives, highlighting how easily isolated studies can be misinterpreted. He stre…

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Beyond Sick Care: Evelyne Bischof on the Rise of Longevity Medicine 56:39

28d ago56:39

56:39

On this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Evelyne Bischof, President of the Healthy Longevity Medicine Society. Evelyne discusses her background in internal medicine and oncology and how her work puzzling together patient diagnoses led her to the field of longevity medicine. She highlights the importance of optimizi…

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Precision Habits: How Wearables and AI Are Powering Personalized Longevity 51:06

1M ago51:06

51:06

In this episode of Longevity by Design, our host, Dr. Gil Blander talks with Dr. Renee Deehan and Paul Fabian about Inside Tracker's new Healthspan Habits Score feature. This innovative tool analyzes data from wearable devices and daily journal entries to identify the most impactful habit to improve each week for better health span and longevity. T…

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Scanning the Future: How Whole-Body MRI is Transforming Longevity with Dr. Daniel Durand 1:22:16

2M ago1:22:16

1:22:16

Dr. Gil Blander welcomes Dr. Daniel Durand, Chief Medical Officer at Prenuvo, to Longevity by Design for a deep dive into the future of preventative healthcare. Dr. Durand shares how full-body MRI is redefining early detection by making advanced imaging accessible, non-invasive, and radiation-free. He explains why MRI, as a soft tissue imaging moda…

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AI, LLMs & The Future of Longevity: Unlocking Healthspan Innovations with Dr. Eran Segal 1:01:54

3M ago1:01:54

1:01:54

In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Eran Segal, Professor at the Weizmann Institute of Science, to explore the intersection of artificial intelligence (AI) and personalized health. The conversation dives into how AI and machine learning are transforming our understanding of nutrition, disease prediction, and ov…

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GLP-1, Wearables & Longevity: What You Need to Know – AMA with Gil & Ashley 49:25

3M ago49:25

49:25

Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 diabetes but now widely used for weight management and longevity. They explore how these medications work, their effects on appetite, metabolism, and inflammation, and why they might be a game-changer for cardiovascular he…

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Muscle, Longevity, and the Power of Protein with Dr. Gabrielle Lyon 1:18:38

4M ago1:18:38

1:18:38

In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Gabrielle Lyon, a board-certified family physician and New York Times bestselling author of Forever Strong. Gabrielle discusses the growing epidemic of sarcopenia, the loss of muscle mass and strength, accelerated by the use of GLP-1 medications. She emphasizes the importance…

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Mickey 17 28:31

4M ago28:31

28:31

This week, we're heading to the planet Niflheim to discuss Mickey 17, the new film by Bong Joon Ho. With multiple Robert Pattinsons, Creepers, and plenty to talk about, it's sure to be an exciting conversation that can’t be duplicated.By Talk Movie To Me

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The Science, Evolution, and Future of Lifespan and Healthspan with Dr. Michael Ringel 1:12:52

4M ago1:12:52

1:12:52

On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Cal…

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OSCAR SPECIAL 2025 57:34

4M ago57:34

57:34

It's that time of year again! Talk Movie To Me is back with our 8th annual Oscar Special, where we break down the nominations, snubs, surprises, and our (probably incorrect) predictions. Tune in for hot takes, heated debates, and our undying love for cinematic excellence (and chaos).By Talk Movie To Me

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How Long Can Humans Live? Insights from Dr. Jay Olshansky 1:10:08

4M ago1:10:08

1:10:08

In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Jay Olshansky, a leading professor at the University of Illinois Chicago and a renowned expert in aging and biodemography. Together, they delve into the science of longevity, exploring how public health advancements in the 20th century revolutionized life expectancy and what…

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A Real Pain 36:00

5M ago36:00

36:00

This week, we discuss A Real Pain, written and directed by Jesse Eisenberg. This isn't your standard buddy road trip movie that's for sure. Kieran is charming, Jesse is awkward and this movie clocks in at the beautiful run time of one hour, thirty minutes. Bless.By Talk Movie To Me

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The Brutalist 40:06

5M ago40:06

40:06

This week, we brave the lengthy runtime and delve into Brady Corbet’s sprawling American epic, The Brutalist. So grab your snacks and plan your pee breaks, because we’re deep-diving into this thematically rich Oscar nominee.By Talk Movie To Me

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Precision Longevity Medicine with Dr. David Barzilai 1:51:36

5M ago1:51:36

1:51:36

Can personalized medicine unlock the secrets to living longer and healthier lives? In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Barzilai, a renowned longevity physician and founder of Barzilai Longevity Consulting, to explore the science of extending healthspan through precision and innovation. Dr. Barzilai …

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Unknown Showgirl 57:26

5M ago57:26

57:26

It’s a showbiz double feature this episode! First up, there’s some heat blowin’ in the wind when Ms Sinclair and Edison fight it out over the Bob Dylan biopic “A Complete Unknown”, starring Timothée Chalamet. Then, in “The Last Showgirl” (31:24) , starring Pamela Anderson, there’s rhinestones and breasts, but what about joy? Tune in to find out!…

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Queer 46:30

5M ago46:30

46:30

This week we delve into the realm on unrequited love. Queer, based off of the novella by William S. Burroughs, is the latest from one of our fav. director's Luca Guadagnino. Listen to hear our many thoughts!By Talk Movie To Me

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How Can a Nutrition AI Platform Help Us Live Healthier and Longer Lives with Dr. Dmitriy Richard Starson 56:24

5M ago56:24

56:24

On this episode of Longevity by Design, Dr. Gil Blander hosts Dr. Dmitriy Richard Starson, Founder and CEO of Passio, an AI-powered nutrition coaching platform. Dmitriy discusses his career path from astrophysics to the world of nutrition tracking. He explains how his company seeks to make healthy eating more accessible. Passio aims to achieve this…

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Most Anticipated 2025 33:52

6M ago33:52

33:52

This week it’s our 8th annual most anticipated episode! We are heading full force into 2025 and leaving the mistakes of 2024 in the dust! Join us while we each pick five movies that we are most excited about!By Talk Movie To Me

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Babeferatu 1:03:17

6M ago1:03:17

1:03:17

In this week’s episode, we sink our teeth into a chilling and sultry double feature: Robert Eggers’ Nosferatu, the atmospheric reimagining of the vampire legend, and Babygirl , the provocative film examining modern eroticism. From the haunting shadows of Count Orlok to Nicole Kidman’s daring performance as a CEO navigating her sexual desire, we exp…

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The Path to a 1,000-Year Lifespan with Dr. Aubrey de Grey 53:55

6M ago53:55

53:55

In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Aubrey de Grey, a biomedical gerontologist, to explore the frontiers of aging research and lifespan extension. Dr. de Grey shares his work identifying and addressing the seven major categories of aging-related diseases. He discusses how targeted damage repair offers a pro…

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Eighth Annual Christmas Special 50:00

6M ago50:00

50:00

It’s our Eighth Annual Christmas Special! Eight years of rum-nogs, joy and fighting about Christmas movies. This year we’re covering 1940’s The Shop Around the Corner, 1984’s Silent Night Deadly Night and 1996’s The Preacher’s Wife. Happy Holidays everyone!By Talk Movie To Me

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Dietary Changes to Reduce the Risk of Prostate Cancer with Dr. John Erdman 37:09

7M ago37:09

37:09

On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. John Erdman to discuss prostate cancer and the impact of diet on disease progression. John shares his personal connection to this disease and why he’s dedicated his research to understanding dietary interventions. John explains that prostate cancer is often slow-growing, with most…

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Gladiator II 42:39

7M ago42:39

42:39

Like hands moving through a wheat field these are the days of the Roman Empire! This week we’ve got baboons, impossible thighs and yes even sharks! Join us while we discuss the colossal Gladiator II.By Talk Movie To Me

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Wicked 44:16

7M ago44:16

44:16

This week on Talk Movie To Me, we’re diving into one of the most anticipated musical adaptations of the year: Wicked! Directed by Jon M. Chu (Crazy Rich Asians, In the Heights), this cinematic take on the Broadway sensation stars Cynthia Erivo as the misunderstood Elphaba and Ariana Grande as Glinda the Good Witch. With stunning visuals, unforgetta…

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Unlocking Longevity: Dr. Jens Juul Holst on GLP-1’s Life-Changing Impact on Metabolic Health 1:23:16

7M ago1:23:16

1:23:16

In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and …

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Emilia Pérez 32:04

7M ago32:04

32:04

For this week’s episode, we’re talking about the film Emilia Pérez, a bloody, violent drug cartel crime thriller. And a story of trans liberation and the joy of living your authentic life. And a pulpy melodrama. Oh, and a MUSICAL. This is a Spanish language film set in the heart of Mexico City but shot in France, by French filmmaker Jacques Audiard…

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Heretic 40:20

7M ago40:20

40:20

This week we're knock knock knockin' on hell's door and asking if you have a moment to discuss our lord and saviour Jesus Christ. Join us while we chat about Hugh Grant in his villain era in Heretic.By Talk Movie To Me

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Food Fermentation and Its Effect on Healthspan with Dr. Jacob Allen and Dr. Mike Miller 47:57

7M ago47:57

47:57

Episode highlights: Introduction: 00:00:00 Why have you decided to become a scientist: 00:02:30 What is fermentation: 00:07:45 What microbes are involved in fermentation: 00:08:40 How those microbes get into the fermented food: 00:09:35 When the Humankind started to utilize fermentation: 00:11:20 What is the difference between Probiotics and Live C…

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Anora 37:34

8M ago37:34

37:34

This week we’re getting swept up in the whirlwind that is ANORA. Join us while we chat about this Palme d’Or winning film by Talk Movie To Me favourite Sean Baker.By Talk Movie To Me

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We Live In Time 31:56

8M ago31:56

31:56

Whether you view time as relative, as an illusion, as linear, as non-linear, as running out, as infinite … whether time is tough, or wasted, or maybe time is money - the undeniable fact is that we live in it. Starring Florence Pugh and Andrew Garfield, “We Live In Time” asks the age-old question: with the precious time that you are given, what do y…

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Taste and Smell Preferences and Their Impact on Health with Dr. Yanina Pepino 1:01:46

8M ago1:01:46

1:01:46

On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Yanina Pepino, Professor of Ingestive Behavior at the University of Illinois, to discuss the fascinating link between taste, personal preferences, and long-term health. Yanina's research shows our food environment significantly shapes cravings. This exposure starts as early as the…

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Halloween Special: The Omen, Child's Play & Oddity 49:48

8M ago49:48

49:48

It's our eighth annual Halloween Special! We're discussing The Omen, Child's Play and Oddity. Listen, IF YOU DARE!By Talk Movie To Me

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Ask Me Anything (AMA): Nutrition Deep Dive with Dr. Gil Blander and Ashley Reaver 22:39

8M ago22:39

22:39

In this special "Ask Me Anything" episode of the Longevity by Design podcast, Ashley Reaver and Dr. Gil Blander from InsideTracker delve into their latest innovation, the Nutrition Nutrition Deep Dive Solution. After years of research and development, they share the journey of creating a food recognition platform that helps users track their food i…

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Joker: Folie à Deux

9M ago

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This week we’re sending in the clowns and in Todd Phillip’s mind that’s us apparently. Did the new Joker make us laugh, cry, or make us wish we were watching a different film?By Talk Movie To Me

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Unlocking the Secrets of Longevity with Dr. David Sinclair 46:23

9M ago46:23

46:23

In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend both lifespan and healthspan. Dr. Sinclair shares his groundbreaking research on the role of epigenetic changes in aging and the potential to reverse…

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Megalopolis 39:00

9M ago39:00

39:00

This week we’re discussing Francis Ford Coppola’s self-financed,giant swing of a film, Megalopolis. Did this Wow (Platinum) us? Or was it a MegaFLOPolis?By Talk Movie To Me

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The Substance 48:44

9M ago48:44

48:44

It’s the Season 8 premiere! And also a pretty epic mmilestone, as this is the 200th episode of Talk Movie To Me *applause* Speaking of epic, we are launching this season with director Coralie Fargeat’s audacious new film “The Substance”, featuring an absolutely unforgettable performance by Demi Moore. What would you do for a more beautiful, more yo…

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The Impact of Artificial Intelligence, Machine Learning, and Large Language Models on Your Health and Wellness With Dr. Renee Deehan 51:26

9M ago51:26

51:26

In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness. Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how…

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Furiosa: A Mad Max Saga 36:24

9M ago36:24

36:24

Start your engines and cover your foreheads in tar because we’re discussing the latest in the Mad Max Saga - Furiosa! In this prequel, George Miller shows us how our titular character, played by Anya Taylor-Joy, came to be. So buckle up and let Hellcat Helen, Sparkplug Edison and Scrapheap Sinclair lead the way.…

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The Surprising Link Between Space Travel and Aging with Dr. David Furman 1:08:34

10M ago1:08:34

1:08:34

On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his groundbreaking research on inflammaging— uncovering how chronic, low-grade i…

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Improvements in Blood and Fitness Tracker Biomarkers in a Digital Health Platform 1:02:33

10M ago1:02:33

1:02:33

In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computatio…

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Parkinson's and Alzheimer's: The Gut-Brain Connection Explored with Dr. Julie Andersen 1:14:00

11M ago1:14:00

1:14:00

In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transformin…

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The impact of ketones on performance and aging with Dr. Brianna Stubbs 1:15:29

11M ago1:15:29

1:15:29

In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging. Dr. Stubbs discusses the …

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The impact of ultra-processed foods and fructose on metabolic health with Dr. Robert Lustig 1:12:48

12M ago1:12:48

1:12:48

In this episode of Longevity by Design, host Dr. Gil Blander talks with Dr. Robert Lustig, an emeritus professor of pediatrics at UCSF and a renowned neuroendocrinologist. Dr. Lustig dives into the impact of ultra-processed foods and fructose on metabolism, emphasizing how these contribute to obesity and metabolic diseases. He also discusses his jo…

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Ask Me Anything (AMA): Optimizing Health & Longevity with Dr. Gil Blander & Ashley Reaver, MS, RD, CSSD 29:55

1y ago29:55

29:55

In this Longevity by Design Ask Me Anything (AMA) episode with Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, the focus is on user questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription model, emphasizing the importance of continuous engagement for long-term health impr…

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Understanding Aging to Extend Healthspan and Longevity with Dr. Gordon Lithgow 48:50

1y ago48:50

48:50

In this episode of Longevity by Design, hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander sit down with Dr. Gordon Lithgow, a Professor and Vice President for Academic Affairs at the Buck Institute for Research on Aging. Dr. Lithgow's research focuses on understanding the mechanisms of aging and identifying genes and small molecules that can p…

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The Idea of You 36:32

1y ago36:32

36:32

On this week’s episode, we're singing songs of love with The Idea of You a film that tries to prove me wrong when I tell all the 20-somethings who message me on dating apps that they’re sweet and naive, but fully wrong when they say age is just a number. Directed by Michael Showalter and starring Annie Hathaway, this film will make you want to dig …

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The Impact of Exercise & Nutrition on Muscle, Tendons, Ligaments, & Aging with Dr. Keith Baar 1:05:58

1y ago1:05:58

1:05:58

In this episode of Longevity By Design, co-hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander welcome renowned professor Dr. Keith Baar. As the head of the Functional Molecular Biology Lab at UC Davis, Dr. Baar has made groundbreaking discoveries about how exercise and nutrition influence the adaptation of muscles, tendons, and ligaments. Durin…

1
Challengers 36:16

1y ago36:16

36:16

It’s about to get sweaty in here because this week we’re discussing Challengers, the new film directed by the maestro of desire, Luca Guadagnino. So join us while we chat tennis, thouples, and churros. It’s game on!By Talk Movie To Me

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The Impact of DNA Damage & Lifestyle on Aging & Longevity Medicine with Dr. Morten Scheibye-Knudsen 1:18:22

1y ago1:18:22

1:18:22

In this episode of Longevity by Design, host Dr. Gil Blander is joined by Dr. Morten Scheibye-Knudsen, a leading figure in aging research. Dr. Scheibye-Knudsen discusses his groundbreaking research on the role of DNA damage in the aging process and its implications for chronic diseases, aging research, and longevity medicine. The goal of his work i…