Best MECO Podcasts (2025)

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T+308: Chatting with Casey Handmer 36:09

Play Pause

13d ago36:09

36:09

Casey Handmer, Founder of Terraform Industries, joins me to talk about the state of NASA in 2025, talent acquisition and retention, productivity, and so much more. This episode of Main Engine Cut Off is brought to you by 34 executive producers—Kris, Joakim (Jo-Kim), Creative Taxi, Heiko, Joel, Frank, Josh from Impulse, The Astrogators at SEE, David…

1
The AI Revolution in Drug Development with Jennifer Bittinger, President and Co-founder of Narrativa 55:52

19d ago55:52

55:52

From TV production to trailblazing in generative AI, Jennifer Bittinger’s journey is anything but ordinary. In this episode of Inside Biotech, Jennifer shares how her non-linear career path–from helping launch Hulu to leading Narrativa–prepared her to bring AI innovation into the life sciences. She reveals how Narrativa became the first company to …

1
T+307: Executive Order on Regulatory Reform (with Tom Marotta) 30:47

24d ago30:47

30:47

Tom Marotta of The Spaceport Company joins me to talk about the executive order this week focused on commercial space regulatory reform, what problems it seeks to solve, his experience on both sides of those issues, and how we should understand the positioning of the order. This episode of Main Engine Cut Off is brought to you by 34 executive produ…

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T+306: Lunar Outpost (with Michael Moreno, VP of Strategy) 41:56

1M ago41:56

41:56

Michael Moreno, VP of Strategy at Lunar Outpost, joins me to talk about what they’ve been up to at the company, the NASA Lunar Terrain Vehicle Services contract, the idea of services as a business on the Moon, and more. This episode of Main Engine Cut Off is brought to you by 35 executive producers—Lee, Russell, Fred, The Astrogators at SEE, David,…

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The Nanas in the Village: Hospitality & Anticipation as a Superpower 52:24

1M ago52:24

52:24

This week Richard and Joe are still unpacking Second Harvest leading to some insights into the concept of hospitality as a skill. Convening the right people, the right way, and letting uncommon outcomes happen is a skill both Richard and Joe have developed over decades and applying these ideas to clients and relationships can yield profound outcome…

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Second Harvest! Behind the Scenes 54:57

1M ago54:57

54:57

Richard and Devon launched Second Harvest in Austria successfully and he's here to spill a ton of behind the scenes details, insights into the event, deeper dives into the unique philosophy behind Second Harvest, how it went, and where it goes from here. This is a must-listen if you've followed this event at all along the way!https://www.secondharv…

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T+305: The Starship 36 Explosion, and ESA Policy (with Adrian Beil, NASASpaceflight) 1:06:14

2M ago1:06:14

1:06:14

A special simulcast of this week’s Off-Nominal—the other show I do, if you somehow haven’t heard of it!—because it’s exactly the topic list with exactly the guest I had up next on my list. I’m joined by Adrian Beil of NASASpaceflight to talk about the recent mayhem at Starbase, and to kick around European space policy topics in the run up to the ES…

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The Biotech Hiring Secret Sauce with Colin Smith, ExecNow CEO 52:55

3M ago52:55

52:55

Biotech is bursting with innovation—from gene editing to AI-powered diagnostics—but behind every successful breakthrough is something far less talked about: leadership. In this episode of Inside Biotech, we’re joined by Colin Smith, CEO and co-founder of ExecNow, a next-gen talent partner helping some of the world’s most innovative biotech, greente…

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T+304: The Musk/Trump Breakup, Jared Isaacman’s Withdrawn Nomination, and Starship Flight 9 (with Lori Garver) 49:36

3M ago49:36

49:36

Lori Garver, former NASA Deputy Administrator, joins me to talk about the chaos of the last week: the withdraw of Jared Isaacman’s nomination for NASA Administrator, Starship Flight 9, and of course, the wild public breakup of Elon Musk and President Trump. This episode of Main Engine Cut Off is brought to you by 33 executive producers—David, Donal…

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Alliance Has Direction 51:43

3M ago51:43

51:43

In this episode, Joe and Richard explore the difference between community and alliance: “An alliance is going someplace… it has direction.” They trade time-travel hypotheticals, reflect on the problem-solving joy of The Martian and The Last of Us, and debate whether their businesses are behaving like nouns or verbs. “Do something with this,” Joe in…

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Solid Diagonal Line Up: Anthony Colangelo & MECO's origin story 51:54

4M ago51:54

51:54

While Richard was away Joe catches up with Anthony Colangelo, partner at Pine Works, host of Main Engine Cut Off & cohost of Off-Nominal, Engineering leader, iOS product developer, birds fan, dad, and Joe's spiritual nephew. Anthony has grown a space flght, exploration, and policy podcast empire rooted in his sincere passion and strong opinions re:…

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CRISPR Campaigns & Beyond: Science Marketing with Elizabeth Chabe, Founder/CEO of High Touch Group 56:55

4M ago56:55

56:55

What does it really take to bring cutting-edge science out of the lab and into the world? In this episode of Inside Biotech, we sit down with Elizabeth Chabe, founder and CEO of High Touch Group, a strategic marketing firm specializing in biotech, medtech, and deep tech. Elizabeth shares her unique journey—from working in a structural engineering l…

1
T+303: The Trump 2024 Transition (with Mark Albrecht) 53:42

4M ago53:42

53:42

Mark Albrecht joins me to talk about his time on the Trump 2024 Transition Team, the thinking behind some of the policy decisions we’re starting to see in the space and national security spheres, and more. This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, The Astrogators at SEE, Will and Lars from Agile, Theo a…

1
T+302: A Tour of Marotta Controls 1:38:45

4M ago1:38:45

1:38:45

We take a tour of Marotta Controls in Montville, New Jersey, to see how they work, how they develop, produce, and test products at rate, and we learn about the most feared topic in space—valves! This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, Josh from Impulse, Heiko, Donald, Stealth Julian, Warren, Kris, Fra…

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T+301: Hypersonics and Constellations (with Caleb Henry) 42:05

4M ago42:05

42:05

Caleb Henry, Director of Research at Quilty Space, joins me to talk megaconstellations, the hypersonics industry, and more. This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, Josh from Impulse, Heiko, Donald, Stealth Julian, Warren, Kris, Frank, Steve, Bob, Better Every Day Studios, The Astrogators at SEE, Joaki…

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T+300: Isaacman’s Confirmation Hearing, NASA and NOAA Budgets, NSSL Phase 3 Lane 2 Awards 26:48

5M ago26:48

26:48

Jared Isaacman was in Congress for a confirmation hearing for his nomination as NASA Administrator, which was followed up by reports of huge proposed budget cuts at NASA and NOAA. And as expected, SpaceX, ULA, and Blue Origin all received awards for NSSL Phase 3 Lane 2. This episode of Main Engine Cut Off is brought to you by 33 executive producers…

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From Neuroscience to OmBiome: Dr. Julia Perederiy on Building a Science-Backed Wellness Brand 52:06

5M ago52:06

52:06

In this episode of Inside Biotech, we sit down with Dr. Julia Perederiy, neuroscientist and Founder of OmBiome, a regenerative health company revolutionizing personal care through microalgae. Julia shares her journey from academia to entrepreneurship, the science behind her mission, and how wellness trends are evolving in today’s market. Tune in fo…

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eHouse Gets Acquired: Reaction Pod + The Philadelphia Experiment starts! 46:00

5M ago46:00

46:00

Richard and Joe break down their conversation with Chris & Aaron Quinn, more details about agency acquisitions, private equity vs venture capital, and they spill the beans about The Philadelphia Experiment April 9-11.By Joe Rinaldi & Richard Banfield

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Little By Little, Then All At Once: eHouse Gets Acquired 56:37

5M ago56:37

56:37

Chris and Aaron Quinn join to share their experiences creating, growing, and ultimately scaling eHouse through an acquisition. Thanks to our friends for being so candid and informative about their experiences!By Joe Rinaldi & Richard Banfield

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T+299: Starliner, According to Butch and Suni (with Eric Berger) 28:50

5M ago28:50

28:50

Eric Berger of Ars Technica joins me to talk about his recent interviews with Butch and Suni in the aftermath of their flight, the update NASA put out about Starliner, and how it all lands from where we are now. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Ryan, David, Theo and Violet, Fred, Steve, Warren, The Ast…

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T+298: Eric Schmidt Takes Over at Relativity, Rocket Lab Plans Mynaric Acquisition 20:05

6M ago20:05

20:05

Eric Schmidt has taken a majority stake in Relativity and will serve as its CEO, so this is a good time to check in on their plans. Rocket Lab is planning to acquire Mynaric, and I have a theory I felt like I needed to float. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Matt, Donald, Frank, David, Lee, Will and La…

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T+297: Firefly Blue Ghost 1, Intuitive Machines IM-2, SpaceX Starship Flight 8 (with Josh Dinner) 52:20

6M ago52:20

52:20

Josh Dinner of Space.com joins me to talk about a wild week in space—Firefly’s Blue Ghost 1, Intuitive Machines’ IM-2, SpaceX’s Starship Flight 8, Rocket Lab announcements, and more. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Stealth Julian, Kris, Heiko, Pat, Jan, Warren, Josh from Impulse, Ryan, Lee, Joel, Davi…

1
Repurposing Drugs & Reinventing Biotech: Dr. Adam Watson on Building MeCo Diagnostics 59:52

6M ago59:52

59:52

In this discussion, Dr. Adam Watson, Co-founder and CEO of MeCo Diagnostics, shares the personal and professional experiences that led him to focus on cancer research and, ultimately, to launch his own company. From the profound influence of his family’s battle with cancer to the long and complex journey of developing the MeCo Score™, he walks us t…

1
Take the Credit Out & Get More Done 30:12

6M ago30:12

30:12

Duolingo announced changing their job titles from UX Design to Product Experience Design and created a 2013-Twitter-era dust up so Richard and Joe chime in with their thoughts. We discuss the purpose of job titles, the way identity effs with you, and to bring it back to sales in a meta way we ask what's more important? That you achieve your objecti…

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T+296: Jim Bridenstine on Space Policy 25:56

6M ago25:56

25:56

Former Congressman and NASA Administrator Jim Bridenstine joins me to talk space policy, then and now: CLPS, Commercial Space Stations, Artemis, international partnerships, and more. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Stealth Julian, Kris, Heiko, Pat, Jan, Warren, Josh from Impulse, Ryan, Lee, Joel, Davi…

MECO Podcasts

1
Main Engine Cut Off

Anthony Colangelo

1
You Can't Lose!

Joe Rinaldi & Richard Banfield

1
Inside Biotech

Gabriella Rubert, Daniel Arce, Katherine Merkling, Serena Gao, Bryan Jimenez, Danielle Luu, Stephanie Wu

1
The Seachange Business Podcast

Michael Vincent

1
T+308: Chatting with Casey Handmer 36:09

1
The AI Revolution in Drug Development with Jennifer Bittinger, President and Co-founder of Narrativa 55:52

1
T+307: Executive Order on Regulatory Reform (with Tom Marotta) 30:47

1
T+306: Lunar Outpost (with Michael Moreno, VP of Strategy) 41:56

1
The Nanas in the Village: Hospitality & Anticipation as a Superpower 52:24

1
Second Harvest! Behind the Scenes 54:57

1
T+305: The Starship 36 Explosion, and ESA Policy (with Adrian Beil, NASASpaceflight) 1:06:14

1
The Biotech Hiring Secret Sauce with Colin Smith, ExecNow CEO 52:55

1
T+304: The Musk/Trump Breakup, Jared Isaacman’s Withdrawn Nomination, and Starship Flight 9 (with Lori Garver) 49:36

1
Alliance Has Direction 51:43

1
Solid Diagonal Line Up: Anthony Colangelo & MECO's origin story 51:54

1
CRISPR Campaigns & Beyond: Science Marketing with Elizabeth Chabe, Founder/CEO of High Touch Group 56:55

1
T+303: The Trump 2024 Transition (with Mark Albrecht) 53:42

1
T+302: A Tour of Marotta Controls 1:38:45

1
T+301: Hypersonics and Constellations (with Caleb Henry) 42:05

1
T+300: Isaacman’s Confirmation Hearing, NASA and NOAA Budgets, NSSL Phase 3 Lane 2 Awards 26:48

1
From Neuroscience to OmBiome: Dr. Julia Perederiy on Building a Science-Backed Wellness Brand 52:06

1
eHouse Gets Acquired: Reaction Pod + The Philadelphia Experiment starts! 46:00

1
Little By Little, Then All At Once: eHouse Gets Acquired 56:37

1
T+299: Starliner, According to Butch and Suni (with Eric Berger) 28:50

1
T+298: Eric Schmidt Takes Over at Relativity, Rocket Lab Plans Mynaric Acquisition 20:05

1
T+297: Firefly Blue Ghost 1, Intuitive Machines IM-2, SpaceX Starship Flight 8 (with Josh Dinner) 52:20

1
Repurposing Drugs & Reinventing Biotech: Dr. Adam Watson on Building MeCo Diagnostics 59:52

1
Take the Credit Out & Get More Done 30:12

1
T+296: Jim Bridenstine on Space Policy 25:56