Best MECO Podcasts (2025)

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Shaping Tomorrow's Researchers with Dr. Reginald Hill, Founder of Lab Lift-off 1:01:01

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1d ago1:01:01

1:01:01

What if we’ve been focusing on the wrong cells in cancer? In this episode, Dr. Reginald Hill explains how fibroblasts, inflammation, and tissue stiffness shape tumor behavior and chemoresistance—and how mouse models, organoids, and microfluidic devices can turn those insights into better diagnostics. We dig into his path from a Cell cover story to …

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T+315: Autonomy in Space (with Simone D’Amico, DJ Bush, and Al Tadros) 1:03:06

12d ago1:03:06

1:03:06

Simone D’Amico of Stanford and EraDrive, DJ Bush of NVIDIA, and Al Tadros of Redwire join me to talk about autonomy in space, to get into the specific details of what they’re working on and how it comes together, and what it may do for the industry in the next few years. This episode of Main Engine Cut Off is brought to you by 32 executive producer…

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T+314: Jockeying for the Artemis 3 Lander, and the NASA Administrator Position 34:59

22d ago34:59

34:59

Thinking through the chaos that has ensued over the NASA Administrator role, the Artemis 3 lander acceleration movement, the SpaceX Starship HLS update, and a bit on how we actually got here. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Donald, Stealth Julian, Jan, Theo and Violet, The Astrogators at SEE, Joakim, …

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T+313: Starlink, Kuiper, Project Bromo, and More (with Caleb Henry) 33:04

23d ago33:04

33:04

Caleb Henry, Director of Research at Quilty Space, joins me (in studio!) to talk about Starlink V3, Starlink satellite relay, Kuiper’s rollout, the Airbus-Thales-Leonardo merger, and the future of Iridium. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Heiko, Joonas, Joel, The Astrogators at SEE, Russell, Joakim, Ti…

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T+312: Starship Flight 11, Space Policy, and Priorities (with Miles O’Brien) 44:18

1M ago44:18

44:18

Miles O’Brien, science correspondent for PBS News and CNN space analyst, joins me to talk about Starship Flight 11, the current space policy landscape including the ongoing government shutdown, the possible return of Jared Isaacman, and what to do about all the competing budget priorities at NASA. This episode of Main Engine Cut Off is brought to y…

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T+311: Phil McAlister on Commercial LEO and NASA’s Human Spaceflight Budget 42:37

1M ago42:37

42:37

Phil McAlister, former Director of NASA’s Commercial Space Division, joins me to talk about the Commercial LEO Destinations program, the budgetary issues facing NASA and its human spaceflight programs, and to share his perspective on the last (and next) few years in these areas. This episode of Main Engine Cut Off is brought to you by 32 executive …

1
The Future of Mental Health Treatment with Shawn Singh, CEO of Vistagen 51:57

1M ago51:57

51:57

CEO of Vistagen, Shawn Singh, returns to Inside Biotech to discuss groundbreaking developments in intranasal therapeutics. Shawn shares exciting results from Vistagen’s fast-track phase 3 trials, explains how intranasal drug delivery bypasses limitations of traditional therapeutics relying on systemic absorption, and reflects on telehealth’s role i…

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Revolutionizing Biotechnology with Exozymes: Michael Heltzen, CEO of Exozymes 1:05:27

2M ago1:05:27

1:05:27

Serial entrepreneur Michael Heltzen, CEO of Exozymes, reveals how his NASDAQ-listed company is "liberating enzymes from cells" to create a new generation of chemical manufacturing. Instead of using living cells as factories, Exozymes isolates enzymatic pathways to work as pure chemistry—achieving engineering-level control previously deemed impossib…

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T+310: NASA’s “Prove It” Era 19:48

2M ago19:48

19:48

NASA selected Blue Origin to (maybe) deliver the once-cancelled VIPER rover, modified Sierra Space’s ISS resupply contract which likely puts the nail in the coffin of Dream Chaser, and released the draft of its new commercial space station strategy. All different stories with one message: prove it. But maybe not in a good way. This episode of Main …

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Diagnosing the Undiagnosed: John Marlow and Pete Kane of Research to the People 53:31

2M ago53:31

53:31

In this episode of Inside Biotech, we sit down with John Marlowe and Pete Kane to explore how patient-driven innovation is transforming research on rare diseases and oncology. John shares his own 15-year medical odyssey filled with misdiagnoses and being told his symptoms were “in his head” and how his relentless determination led him to long-read …

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T+309: EchoStar’s Spectrum Sale, Starlink’s Financials (with Caleb Henry, Director of Research at Quilty Space) 43:01

2M ago43:01

43:01

Caleb Henry, Director of Research at Quilty Space, joins me to talk about EchoStar’s spectrum sales and constellation cancellation, SpaceX’s spectrum purchase, and the financials of Starlink. This episode of Main Engine Cut Off is brought to you by 34 executive producers—Bob, Heiko, Creative Taxi, Josh from Impulse, Russell, Donald, Will and Lars f…

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T+308: Chatting with Casey Handmer 36:09

3M ago36:09

36:09

Casey Handmer, Founder of Terraform Industries, joins me to talk about the state of NASA in 2025, talent acquisition and retention, productivity, and so much more. This episode of Main Engine Cut Off is brought to you by 34 executive producers—Kris, Joakim (Jo-Kim), Creative Taxi, Heiko, Joel, Frank, Josh from Impulse, The Astrogators at SEE, David…

1
The AI Revolution in Drug Development with Jennifer Bittinger, President and Co-founder of Narrativa 55:52

3M ago55:52

55:52

From TV production to trailblazing in generative AI, Jennifer Bittinger’s journey is anything but ordinary. In this episode of Inside Biotech, Jennifer shares how her non-linear career path–from helping launch Hulu to leading Narrativa–prepared her to bring AI innovation into the life sciences. She reveals how Narrativa became the first company to …

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T+307: Executive Order on Regulatory Reform (with Tom Marotta) 30:47

3M ago30:47

30:47

Tom Marotta of The Spaceport Company joins me to talk about the executive order this week focused on commercial space regulatory reform, what problems it seeks to solve, his experience on both sides of those issues, and how we should understand the positioning of the order. This episode of Main Engine Cut Off is brought to you by 34 executive produ…

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T+306: Lunar Outpost (with Michael Moreno, VP of Strategy) 41:56

4M ago41:56

41:56

Michael Moreno, VP of Strategy at Lunar Outpost, joins me to talk about what they’ve been up to at the company, the NASA Lunar Terrain Vehicle Services contract, the idea of services as a business on the Moon, and more. This episode of Main Engine Cut Off is brought to you by 35 executive producers—Lee, Russell, Fred, The Astrogators at SEE, David,…

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T+305: The Starship 36 Explosion, and ESA Policy (with Adrian Beil, NASASpaceflight) 1:06:14

5M ago1:06:14

1:06:14

A special simulcast of this week’s Off-Nominal—the other show I do, if you somehow haven’t heard of it!—because it’s exactly the topic list with exactly the guest I had up next on my list. I’m joined by Adrian Beil of NASASpaceflight to talk about the recent mayhem at Starbase, and to kick around European space policy topics in the run up to the ES…

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The Biotech Hiring Secret Sauce with Colin Smith, ExecNow CEO 52:55

5M ago52:55

52:55

Biotech is bursting with innovation—from gene editing to AI-powered diagnostics—but behind every successful breakthrough is something far less talked about: leadership. In this episode of Inside Biotech, we’re joined by Colin Smith, CEO and co-founder of ExecNow, a next-gen talent partner helping some of the world’s most innovative biotech, greente…

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T+304: The Musk/Trump Breakup, Jared Isaacman’s Withdrawn Nomination, and Starship Flight 9 (with Lori Garver) 49:36

6M ago49:36

49:36

Lori Garver, former NASA Deputy Administrator, joins me to talk about the chaos of the last week: the withdraw of Jared Isaacman’s nomination for NASA Administrator, Starship Flight 9, and of course, the wild public breakup of Elon Musk and President Trump. This episode of Main Engine Cut Off is brought to you by 33 executive producers—David, Donal…

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CRISPR Campaigns & Beyond: Science Marketing with Elizabeth Chabe, Founder/CEO of High Touch Group 56:55

6M ago56:55

56:55

What does it really take to bring cutting-edge science out of the lab and into the world? In this episode of Inside Biotech, we sit down with Elizabeth Chabe, founder and CEO of High Touch Group, a strategic marketing firm specializing in biotech, medtech, and deep tech. Elizabeth shares her unique journey—from working in a structural engineering l…

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T+303: The Trump 2024 Transition (with Mark Albrecht) 53:42

7M ago53:42

53:42

Mark Albrecht joins me to talk about his time on the Trump 2024 Transition Team, the thinking behind some of the policy decisions we’re starting to see in the space and national security spheres, and more. This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, The Astrogators at SEE, Will and Lars from Agile, Theo a…

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T+302: A Tour of Marotta Controls 1:38:45

7M ago1:38:45

1:38:45

We take a tour of Marotta Controls in Montville, New Jersey, to see how they work, how they develop, produce, and test products at rate, and we learn about the most feared topic in space—valves! This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, Josh from Impulse, Heiko, Donald, Stealth Julian, Warren, Kris, Fra…

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T+301: Hypersonics and Constellations (with Caleb Henry) 42:05

7M ago42:05

42:05

Caleb Henry, Director of Research at Quilty Space, joins me to talk megaconstellations, the hypersonics industry, and more. This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, Josh from Impulse, Heiko, Donald, Stealth Julian, Warren, Kris, Frank, Steve, Bob, Better Every Day Studios, The Astrogators at SEE, Joaki…

MECO Podcasts

1
Main Engine Cut Off

Anthony Colangelo

1
Inside Biotech

Gabriella Rubert, Daniel Arce, Katherine Merkling, Serena Gao, Bryan Jimenez, Danielle Luu, Stephanie Wu

1
The Seachange Business Podcast

Michael Vincent

1
Shaping Tomorrow's Researchers with Dr. Reginald Hill, Founder of Lab Lift-off 1:01:01

1
T+315: Autonomy in Space (with Simone D’Amico, DJ Bush, and Al Tadros) 1:03:06

1
T+314: Jockeying for the Artemis 3 Lander, and the NASA Administrator Position 34:59

1
T+313: Starlink, Kuiper, Project Bromo, and More (with Caleb Henry) 33:04

1
T+312: Starship Flight 11, Space Policy, and Priorities (with Miles O’Brien) 44:18

1
T+311: Phil McAlister on Commercial LEO and NASA’s Human Spaceflight Budget 42:37

1
The Future of Mental Health Treatment with Shawn Singh, CEO of Vistagen 51:57

1
Revolutionizing Biotechnology with Exozymes: Michael Heltzen, CEO of Exozymes 1:05:27

1
T+310: NASA’s “Prove It” Era 19:48

1
Diagnosing the Undiagnosed: John Marlow and Pete Kane of Research to the People 53:31

1
T+309: EchoStar’s Spectrum Sale, Starlink’s Financials (with Caleb Henry, Director of Research at Quilty Space) 43:01

1
T+308: Chatting with Casey Handmer 36:09

1
The AI Revolution in Drug Development with Jennifer Bittinger, President and Co-founder of Narrativa 55:52

1
T+307: Executive Order on Regulatory Reform (with Tom Marotta) 30:47

1
T+306: Lunar Outpost (with Michael Moreno, VP of Strategy) 41:56

1
T+305: The Starship 36 Explosion, and ESA Policy (with Adrian Beil, NASASpaceflight) 1:06:14

1
The Biotech Hiring Secret Sauce with Colin Smith, ExecNow CEO 52:55

1
T+304: The Musk/Trump Breakup, Jared Isaacman’s Withdrawn Nomination, and Starship Flight 9 (with Lori Garver) 49:36

1
CRISPR Campaigns & Beyond: Science Marketing with Elizabeth Chabe, Founder/CEO of High Touch Group 56:55

1
T+303: The Trump 2024 Transition (with Mark Albrecht) 53:42

1
T+302: A Tour of Marotta Controls 1:38:45

1
T+301: Hypersonics and Constellations (with Caleb Henry) 42:05