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Trial by Data

Litmus Health

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Trial by Data, presented by Litmus Health, is a podcast exploring the data-driven technologies and strategies shaping the future of clinical trials. We cover the most pressing issues and questions facing researchers and clinicians today, in an ever-changing landscape. Listen in as we interview leaders and innovators in the field who are at the forefront of developing and using these data-driven approaches.
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Would you like to reduce your alcohol consumption by 80 percent so you can enjoy drinking socially without relying on alcohol to manage your stress, anxiety, loneliness and boredom when you're by yourself? Most high achieving women assume over-drinking is caused by a lack of willpower--or worse, the incurable disease of "alcoholism." So they beat themselves up and avoid asking for help because they feel ashamed and out of control. Whether you’re a daily drinker who can’t break the habit, or ...
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If you’ve been trying to change so that you can feel ready, healed, better and in control, this episode will explain how it’s possible to feel those things now–before you’ve figured everything out. I’m going to explain how to access your higher self—not as a future fantasy, or as someone you’ll be someday when you get everything right, but as a rea…
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In this episode, Colleen shares a quiet but powerful moment from one of her recent coaching calls—where a client celebrated a huge win, and Colleen noticed her own body signaling that something was off. What unfolded wasn’t a rupture, but a subtle shift: a reminder that even seasoned leaders can bypass consent in moments of well-meaning reflex. And…
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In today's episode, Colleen walks us through a deceptively simple question that came up on a recent coaching call: How do I actually feel my feelings? The answer isn’t mindset. It isn’t a technique. It’s presence. She explores the difference between thinking about emotions and physically experiencing them—without adding a story, a solution, or a la…
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Click here to watch this episode on YouTube! If you've ever wondered whether medication could help you drink less — or you’ve tried naltrexone and felt disappointed — this episode is for you. I’m joined by Katie Lain, founder of Thrive Recovery and a fierce advocate for the Sinclair Method — a science-backed approach that uses naltrexone to reduce …
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In today’s episode, Colleen shares a personal and refreshingly honest story about her relationship with nicotine—and how emotional sobriety has shifted the way she responds to temporary imbalance. What starts as a candid reflection on sneaky vape relapses becomes a powerful reminder that healing isn’t about perfection. It’s about how we respond whe…
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In today’s episode, Colleen lifts the veil on a common self-sabotage mechanism that often flies under the radar: worry. What begins as a moment of genuine joy and success quickly dissolves into anxiety—and not because something actually went wrong, but because her nervous system quietly panicked at how good it all felt. Using a relatable personal s…
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Click here to watch on YouTube! If you’ve ever done an alcohol free challenge for 30, 60 or 90 days, maybe even a year, only to fall back into old habits when you started drinking again— this episode is for you. In today’s deep dive, Colleen Freeland explains why behavior-based sobriety models (like Sober Sis, Annie Grace, and Casey Davidson’s appr…
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In today’s episode, Colleen peels back the curtain on one of the most radical shifts we can make: recognizing that we are not our thoughts—we’re the observer behind them. What starts as a reflection on managing the energy in your body becomes a masterclass in emotional authorship, reminding us that our thoughts, not our circumstances, are what crea…
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In today’s episode, Colleen walks us through a high-stakes moment with one of her clients—standing at the emotional fork in the road between old habits and radical self-responsibility. After a tense night at her childhood home, surrounded by triggering family dynamics and judgment, this client found herself spiraling into shame after a single shot …
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Click here to register for the neural rewrite masterclass! How to escape your negative self-talk. Click here to watch this episode on YouTube! What happens when you’re the person everyone counts and you’re secretly falling apart? In this episode, Colleen sits down with tech founder, entrepreneur and coach Mike Hardenbrook for an honest conversation…
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In today’s episode, Colleen shares a real-life moment of emotional sobriety in action—when an old blog post, a rogue email, and a morning scroll tried to hijack her peace before she even got out of bed. What begins as a minor tech task quickly spirals into a stress response… until she catches it. Instead of reacting from urgency, she pauses, reconn…
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In today’s episode, Colleen reveals the sneaky way our own thoughts quietly become emotional abuse—and how to interrupt the habit of thinking things that hurt. From bedtime mirror pep talks to buried beliefs about being “a hot mess,” this episode explores how subconscious thought loops create the feelings that sabotage your confidence, relationship…
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Click here to register for the Rewrite Neural Pathways to Escape Negative Self-Talk Workshop on July 12th Click here to watch this episode on YouTube Do you have confidence and discipline in most areas of your life, and feel befuddled as to why your drinking feels so hard to control? If your drinking feels out of alignment with your values, your go…
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In today’s episode, Colleen unpacks why your background alarm is going off—and how to finally turn it off. You’re not lazy. You’re not broken. And your bedtime resistance, your anxious spinouts, your self-sabotage? They’re not random. They. Are. Patterns. Habits formed by younger versions of you who were just trying to stay safe. This episode dives…
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You’ve probably heard me say the common phrase “the call is coming from inside the house” — but what if every judgment you make about someone else is too? In this episode, Colleen unpacks the concept of The Black Mirror — the idea that your emotional reactions to other people are often projections of the stories, beliefs, and insecurities you hold …
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Click here to watch the full interview with Carley on YouTube In Part 2 of Carley’s story, we dive into the healing that began once she joined the program. You’ll hear how she learned to regulate her nervous system, rewire her brain, and change the story she told herself about who she was. Carley shares how she finally stopped chasing external vali…
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Most women don’t realize how uncomfortable they are with feeling good—until things start going too well. That’s when the sabotage creeps in. A snappy comment. A skipped workout. An unnecessary glass of wine. In today’s episode, Colleen breaks down the concept of the “upper limit problem” from The Big Leap by Gay Hendricks—and explains how perfectio…
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In today’s episode, Colleen shares a powerful one-on-one coaching conversation with a client who was dreading a weekend trip with her judgmental, high-maintenance mother-in-law. What started as a fear of overdrinking turned into something much deeper—a real-time lesson in emotional ownership, boundaries, and what it means to become unfuckwithable. …
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Click here to watch the full interview with Carley on YouTube In this raw and relatable conversation, I’m joined by one of my incredible clients, Carley — a driven healthcare professional, mom of two, and former daily drinker who once believed her only two choices were to either quit drinking forever or keep white-knuckling it with shame and regret…
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In today’s episode, Colleen unpacks a subtle but powerful mindset that can completely shift how you experience stress, pressure, and time. Whether it’s a packed calendar, an airport sprint, or your own inner critic barking about everything you should be doing, the real problem isn’t your to-do list—it’s your nervous system. This episode explores ho…
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If you’re drinking more than you want to, but every time you try to cut back it feels like one more thing to do… this episode is for you. Today, I’m sharing the real story that kept me stuck in the drinking cycle for years—the one that has nothing to do with alcohol: 🙋🏼‍♀️ “I don’t have enough time.” From the liquor store parking lot to the 87-item…
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In today’s episode, Colleen shares a personal reflection on what it means to stay emotionally sober when things are going really well. When the business is booming, the boxes are checked, and it feels like everything is finally clicking. Most of us assume that emotional work is about learning how to handle hard moments—grief, anxiety, cravings, con…
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In this episode, Colleen breaks down the difference between thinking your feelings and actually feeling them—and why most high-achieving women get stuck in a loop that keeps them stressed, stuck, and searching for answers in the wrong places. You’ll learn a simple, body-based skill that helps you shift out of emotional overwhelm and back into clari…
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Today’s episode is for the woman who’s doing everything right—and still feels like she’s falling apart. Colleen sits down with Laurie James, somatic coach and author of Sandwiched: A Memoir of Holding On and Letting Go to talk about what happens when your nervous system hits a breaking point. Laurie ended up in the hospital—twice—after leaving a to…
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Most of us see anxiety as a personal flaw—something to fix, medicate, or avoid. But what if anxiety isn’t the problem at all? What if it’s the invitation? In today’s episode, Colleen breaks down the two types of anxiety as explained by Dr. Russell Kennedy—foreground alarm and background alarm—and shares a personal story of how unresolved fears and …
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In today’s episode, Colleen dismantles one of the most common mindset traps she see's in her clients: the belief that anxiety is something to get rid of. If you’ve ever said, “I’m just an anxious person,” or used alcohol to calm your nerves before a flight, presentation, or party—you’re not alone. But what if anxiety itself isn’t the problem? She'l…
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After 10 months of consistent progress, one of my clients recently found herself drinking every day for two weeks. In this episode, I walk you through the private coaching conversation we had—what really caused the setback, how she responded, and why it had nothing to do with alcohol. If you’ve ever told yourself “I should be farther along by now,”…
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In today's episode, you’ll hear a deeply personal story about the night Colleen’s college-age kids brought home a big bottle of vodka—and invited her to join them. Years ago, this would’ve been the moment she feared the most. But something powerful has shifted. You’ll hear how self-trust changes everything, how desire—not discipline—is what drives …
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If the solution to alcohol use disorder isn’t a behavior, but a feeling— HOW THE HELL DO YOU PRACTICE A FEELING? In today’s episode, Colleen breaks down the mindset shift that will completely change the way you think about manifestation. Not the toxic, glittery, vision-board version. But the grounded, neuroscience-backed practice of training your b…
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Most women assume their drinking habit is a willpower issue. But what if your body is actually sounding an alarm? In today’s episode, Colleen sits down with functional medicine expert Dr. Meg Mill to unpack the hidden connection between histamines, hormones, and alcohol. If your wine tolerance has changed, your moods are all over the place, or you’…
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In today's episode, Colleen shares a story about a client who unsubscribed from her email list—and how that one glitch almost triggered a cascade of false assumptions, unspoken tension, and missed opportunity. It’s a reminder that the smallest emotional reactions (the ones that barely register) are often the most dangerous. Because they go unchecke…
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In today’s episode, Colleen shares the most powerful skill you can develop on your emotional sobriety journey: how you respond to yourself when you slip into old habits. Whether you drank more than you planned or simply feel like you’ve lost your way again, this episode will rewire how you think about failure—and help you stop reinforcing the very …
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Today’s episode is a must-listen for any woman navigating midlife hormonal changes and struggling with overdrinking. Colleen sits down with Bria Gadd—the Period Whisperer—to talk about the real reason so many high-achieving women hit a wall in their 30s and 40s. This is an honest conversation about how to hear your body’s whispers before they becom…
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In today’s episode, Colleen shares a simple and powerful practice that can shift your energy in seconds—and help you stop carrying what your body is desperate to let go of. If you’ve ever felt like you should stop drinking, overworking, or people-pleasing—but you keep doing it anyway—this episode will show you why resistance doesn’t work, and how t…
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Today’s episode is all about emotional flow—how energy moves through your body and what to do when it gets stuck. Colleen explains how your thoughts can block the natural upward movement of desire, inspiration, and curiosity—reversing the flow and creating emotional heaviness, anxiety, and burnout. You’ll learn why it’s not always necessary to unpa…
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In this episode, Dr. Aimee joins Colleen to explain what it really means to have “stored trauma” in the body—and why unresolved trauma often shows up not as flashbacks, but as fatigue, perfectionism, people-pleasing, and habits like nightly drinking. You’ll hear how trauma is stored at the cellular level, why cognitive awareness isn’t enough to hea…
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Today’s episode is all about the practice of being okay no matter what. Colleen shares the mindset shift that changed everything for her—especially while growing her business on TikTok—and how you can apply the same concept to anything in your life. Whether it's tech glitches, traffic, or your partner’s tone of voice, there’s always an invitation t…
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In today’s episode, Colleen shares a powerful mindset shift that can make changing any habit feel easier, faster, and more sustainable: stop trying to "get it right" — just focus on getting it better. Inspired by the concept of the iterative mindset from Dr. Kira Bobinet's research, Colleen explains why the old black-and-white idea of relapse and f…
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On today's episode, Colleen answers a question from a listener who’s successfully changed her own drinking habits—but finds herself frustrated by her husband’s drinking. If you’ve ever felt like someone else’s behavior is sabotaging your progress, this episode will help you take back your emotional power. Colleen walks through her framework for emo…
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In this episode, Colleen invites you to take your emotional temperature and ask a powerful question that could change everything: How can I make this fun and easy? Whether you’re racing through your day with a nervous system stuck in overdrive or stuck in bed with your to-do list haunting you, the solution isn’t more hustle—it’s ease. But ease isn’…
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In today’s episode, Colleen shares a raw and relatable story about frustration, tech fails, and the moment she remembered one of the most powerful tools she teaches: making friends with your feelings. You’ll hear how a seemingly small trigger (a broken download link before a long workday) became the perfect opportunity to practice emotional sobriet…
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Colleen answers a listener question from a woman who’s done incredible work reducing her drinking—but still finds herself overdoing it when she’s with her best friend. Sound familiar? Whether it’s wine with your ride-or-die or happy hour with the same old crew, this episode gives you the tools to enjoy yourself and feel good the next morning. Colle…
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In today's episode, Colleen breaks down how the language you use—especially when it seems neutral or logical—can silently sabotage your ability to change. You’ll hear why “I just need to stop drinking” is actually a negative thought (and how it keeps your brain stuck in the problem instead of moving toward the solution). She explains how to recogni…
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In today’s episode, Colleen shares a personal reflection she recorded nearly a year ago—but it’s just as relevant now, especially if you’re feeling stuck, off-balance, or like a hot mess who should be further along by now. This episode isn’t about getting it all together—it’s about what to do when you don’t. You’ll hear how she used the exact tools…
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"Stop saying that you want to stay sober or drink in moderation. Because what you really want is to feel calm, capable, and in control." Colleen Freeland Kachmann There are 3 invisible, unmet needs that keep high-achieving women from easily changing their drinking habits: a lack of connection, direction and feedback. If you’ve ever wondered “Why am…
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In today’s episode, we’re flipping the script on what it means to “manifest change” when it comes to your relationship with alcohol. Every habit you have was built through attention, repetition, and belief. You already know how to manifest. You’ve done it before. The question is: can you do it on purpose? If you’ve ever told yourself “I know better…
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In today’s episode, we explore a powerful lightbulb moment from inside the Next Chapter program—one that’s helping women actually enjoy the mindful drinking experiment and finally feel real momentum. This is for you if you’ve meant to try mindful drinking but skipped it, overdid it, or didn’t enjoy the process. That’s not a failure—it’s a sign you …
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On December 6th, 2023, I made the scariest—and most transformative—decision of my life. I chose to believe in myself. Not in a "feel-good" kind of way, but in a way that demanded action before certainty and courage before confidence. This episode is a personal snapshot from that turning point—a moment when I faced fear, financial dependence, and se…
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In today’s episode, you’ll explore one of the most common patterns that keeps high-achieving women stuck: worrying about what other people might think. Colleen breaks down how the fear of being misunderstood, judged, or perceived a certain way can quietly derail your growth, your boundaries, and your goals. You’ll learn why managing other people’s …
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In this reflective episode, Colleen shares a personal moment from a particularly full chapter in her life—a season of growth, transition, and pushing hard to bring her program to life. What began as a weekend packed with work turned into a deeper realization about brain fog, creative blocks, and the quiet wisdom of the body. If you’ve ever tried to…
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