The Keith and Kelly Show is a weekly real estate podcast focused squarely on the real estate agent and their success. We basically have two characters from different backgrounds converging on a topic that both know very well – the world of real estate. Keith Robert Gordon is a real estate broker and businessperson. Kelly Moser is a professional high-performance coach. Keith brings his vast expertise as a veteran broker since 1984 with over 4000 closed sell-side transactions, the author of “T ...
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Longevity by Design is your go-to podcast for unlocking the secrets to a longer, healthier life. Hosted by Dr. Gil Blander, a renowned scientist and entrepreneur in the fields of aging, nutrition, and personalized health, this show dives into cutting-edge research and practical strategies for optimizing your healthspan and lifespan. In each episode, Dr. Blander sits down with leading longevity and health scientists to explore how we can live better, longer lives. From unpacking complex scien ...
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Precision Habits: How Wearables and AI Are Powering Personalized Longevity
51:06
51:06
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51:06In this episode of Longevity by Design, our host, Dr. Gil Blander talks with Dr. Renee Deehan and Paul Fabian about Inside Tracker's new Healthspan Habits Score feature. This innovative tool analyzes data from wearable devices and daily journal entries to identify the most impactful habit to improve each week for better health span and longevity. T…
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Scanning the Future: How Whole-Body MRI is Transforming Longevity with Dr. Daniel Durand
1:22:16
1:22:16
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1:22:16Dr. Gil Blander welcomes Dr. Daniel Durand, Chief Medical Officer at Prenuvo, to Longevity by Design for a deep dive into the future of preventative healthcare. Dr. Durand shares how full-body MRI is redefining early detection by making advanced imaging accessible, non-invasive, and radiation-free. He explains why MRI, as a soft tissue imaging moda…
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AI, LLMs & The Future of Longevity: Unlocking Healthspan Innovations with Dr. Eran Segal
1:01:54
1:01:54
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1:01:54In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Eran Segal, Professor at the Weizmann Institute of Science, to explore the intersection of artificial intelligence (AI) and personalized health. The conversation dives into how AI and machine learning are transforming our understanding of nutrition, disease prediction, and ov…
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GLP-1, Wearables & Longevity: What You Need to Know – AMA with Gil & Ashley
49:25
49:25
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49:25Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 diabetes but now widely used for weight management and longevity. They explore how these medications work, their effects on appetite, metabolism, and inflammation, and why they might be a game-changer for cardiovascular he…
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Muscle, Longevity, and the Power of Protein with Dr. Gabrielle Lyon
1:18:38
1:18:38
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1:18:38In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Gabrielle Lyon, a board-certified family physician and New York Times bestselling author of Forever Strong. Gabrielle discusses the growing epidemic of sarcopenia, the loss of muscle mass and strength, accelerated by the use of GLP-1 medications. She emphasizes the importance…
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The Science, Evolution, and Future of Lifespan and Healthspan with Dr. Michael Ringel
1:12:52
1:12:52
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1:12:52On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Cal…
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How Long Can Humans Live? Insights from Dr. Jay Olshansky
1:10:08
1:10:08
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1:10:08In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Jay Olshansky, a leading professor at the University of Illinois Chicago and a renowned expert in aging and biodemography. Together, they delve into the science of longevity, exploring how public health advancements in the 20th century revolutionized life expectancy and what…
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Precision Longevity Medicine with Dr. David Barzilai
1:51:36
1:51:36
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1:51:36Can personalized medicine unlock the secrets to living longer and healthier lives? In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Barzilai, a renowned longevity physician and founder of Barzilai Longevity Consulting, to explore the science of extending healthspan through precision and innovation. Dr. Barzilai …
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How Can a Nutrition AI Platform Help Us Live Healthier and Longer Lives with Dr. Dmitriy Richard Starson
56:24
56:24
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56:24On this episode of Longevity by Design, Dr. Gil Blander hosts Dr. Dmitriy Richard Starson, Founder and CEO of Passio, an AI-powered nutrition coaching platform. Dmitriy discusses his career path from astrophysics to the world of nutrition tracking. He explains how his company seeks to make healthy eating more accessible. Passio aims to achieve this…
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The Path to a 1,000-Year Lifespan with Dr. Aubrey de Grey
53:55
53:55
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53:55In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Aubrey de Grey, a biomedical gerontologist, to explore the frontiers of aging research and lifespan extension. Dr. de Grey shares his work identifying and addressing the seven major categories of aging-related diseases. He discusses how targeted damage repair offers a pro…
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Dietary Changes to Reduce the Risk of Prostate Cancer with Dr. John Erdman
37:09
37:09
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37:09On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. John Erdman to discuss prostate cancer and the impact of diet on disease progression. John shares his personal connection to this disease and why he’s dedicated his research to understanding dietary interventions. John explains that prostate cancer is often slow-growing, with most…
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Unlocking Longevity: Dr. Jens Juul Holst on GLP-1’s Life-Changing Impact on Metabolic Health
1:23:16
1:23:16
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1:23:16In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and …
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Food Fermentation and Its Effect on Healthspan with Dr. Jacob Allen and Dr. Mike Miller
47:57
47:57
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47:57Episode highlights: Introduction: 00:00:00 Why have you decided to become a scientist: 00:02:30 What is fermentation: 00:07:45 What microbes are involved in fermentation: 00:08:40 How those microbes get into the fermented food: 00:09:35 When the Humankind started to utilize fermentation: 00:11:20 What is the difference between Probiotics and Live C…
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Taste and Smell Preferences and Their Impact on Health with Dr. Yanina Pepino
1:01:46
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1:01:46On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Yanina Pepino, Professor of Ingestive Behavior at the University of Illinois, to discuss the fascinating link between taste, personal preferences, and long-term health. Yanina's research shows our food environment significantly shapes cravings. This exposure starts as early as the…
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Ask Me Anything (AMA): Nutrition Deep Dive with Dr. Gil Blander and Ashley Reaver
22:39
22:39
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22:39In this special "Ask Me Anything" episode of the Longevity by Design podcast, Ashley Reaver and Dr. Gil Blander from InsideTracker delve into their latest innovation, the Nutrition Nutrition Deep Dive Solution. After years of research and development, they share the journey of creating a food recognition platform that helps users track their food i…
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Unlocking the Secrets of Longevity with Dr. David Sinclair
46:23
46:23
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46:23In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend both lifespan and healthspan. Dr. Sinclair shares his groundbreaking research on the role of epigenetic changes in aging and the potential to reverse…
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The Impact of Artificial Intelligence, Machine Learning, and Large Language Models on Your Health and Wellness With Dr. Renee Deehan
51:26
51:26
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51:26In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness. Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how…
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The Surprising Link Between Space Travel and Aging with Dr. David Furman
1:08:34
1:08:34
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1:08:34On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his groundbreaking research on inflammaging— uncovering how chronic, low-grade i…
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Improvements in Blood and Fitness Tracker Biomarkers in a Digital Health Platform
1:02:33
1:02:33
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1:02:33In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computatio…
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Parkinson's and Alzheimer's: The Gut-Brain Connection Explored with Dr. Julie Andersen
1:14:00
1:14:00
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1:14:00In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transformin…
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The impact of ketones on performance and aging with Dr. Brianna Stubbs
1:15:29
1:15:29
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1:15:29In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging. Dr. Stubbs discusses the …
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The impact of ultra-processed foods and fructose on metabolic health with Dr. Robert Lustig
1:12:48
1:12:48
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1:12:48In this episode of Longevity by Design, host Dr. Gil Blander talks with Dr. Robert Lustig, an emeritus professor of pediatrics at UCSF and a renowned neuroendocrinologist. Dr. Lustig dives into the impact of ultra-processed foods and fructose on metabolism, emphasizing how these contribute to obesity and metabolic diseases. He also discusses his jo…
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Ask Me Anything (AMA): Optimizing Health & Longevity with Dr. Gil Blander & Ashley Reaver, MS, RD, CSSD
29:55
29:55
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29:55In this Longevity by Design Ask Me Anything (AMA) episode with Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, the focus is on user questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription model, emphasizing the importance of continuous engagement for long-term health impr…
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Understanding Aging to Extend Healthspan and Longevity with Dr. Gordon Lithgow
48:50
48:50
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48:50In this episode of Longevity by Design, hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander sit down with Dr. Gordon Lithgow, a Professor and Vice President for Academic Affairs at the Buck Institute for Research on Aging. Dr. Lithgow's research focuses on understanding the mechanisms of aging and identifying genes and small molecules that can p…
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The Impact of Exercise & Nutrition on Muscle, Tendons, Ligaments, & Aging with Dr. Keith Baar
1:05:58
1:05:58
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1:05:58In this episode of Longevity By Design, co-hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander welcome renowned professor Dr. Keith Baar. As the head of the Functional Molecular Biology Lab at UC Davis, Dr. Baar has made groundbreaking discoveries about how exercise and nutrition influence the adaptation of muscles, tendons, and ligaments. Durin…
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The Impact of DNA Damage & Lifestyle on Aging & Longevity Medicine with Dr. Morten Scheibye-Knudsen
1:18:22
1:18:22
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1:18:22In this episode of Longevity by Design, host Dr. Gil Blander is joined by Dr. Morten Scheibye-Knudsen, a leading figure in aging research. Dr. Scheibye-Knudsen discusses his groundbreaking research on the role of DNA damage in the aging process and its implications for chronic diseases, aging research, and longevity medicine. The goal of his work i…
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The Effects of Cellular Senescence and Senolytics on Healthspan with Dr. James Kirkland
1:12:14
1:12:14
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1:12:14Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. This episode is a deep dive into aging research, cellular…
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Aging, Mental Health, Suicide Risk & Prevention with Dr. Peter Franz
39:15
39:15
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39:15This episode of Longevity by Design discusses mental health and suicide risk and prevention. The following topics are discussed: depression, suicide, substance abuse, social isolation, among others also. This episode is intended to raise awareness of mental health issues and suicide risk and prevention. The topics discussed may be distressing or tr…
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XPRIZE Healthspan: Revolutionizing Human Aging & Healthspan with Dr. Jamie Justice
1:07:49
1:07:49
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1:07:49Can we find ways to target human aging and extend healthspan? This ambitious premise is at the heart of XPRIZE Healthspan, a 7-year, $101 million global competition with an audacious challenge: to successfully develop a proactive, accessible therapeutic that restores muscle, cognitive, and immune function by a minimum of 10 years, with a goal of 20…
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Longevity Genes, Blood Biomarkers of Aging, & Targeting Aging with Metformin with Dr. Nir Barzilai
1:19:26
1:19:26
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1:19:26Aging is inevitable, but can we influence how we age? In this episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, interview Dr. Nir Barzilai—the Director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Resear…
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The Impact of Exercise on Blood Biomarkers and InsideTracker’s New DNA Healthspan Report with Dr. Bartek Nogal
39:49
39:49
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39:49In this episode of Longevity by Design, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, sit down with Dr. Bartek Nogal from InsideTracker to explore the cutting-edge intersections of exercise, genetics, blood biomarkers, health optimization, and longevity. Dr. Bartek Nogal, with a strong background in biological engineering and genomics, dives int…
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Ask Me Anything (AMA): Oral Health, Healthspan, and Longevity with Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD
55:45
55:45
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55:45Did you know that your oral health has a profound impact on healthspan and longevity? Do you want to learn about the connections between oral health, healthspan, and longevity and what you can do to improve your oral health to help you live longer and add more healthy years to your life? This episode of Longevity by Design is an Ask Me Anything (AM…
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How Our Blood Impacts Brain Aging and Alzheimer’s Disease with Dr. Tony Wyss-Coray
1:21:44
1:21:44
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1:21:44In this insightful episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver welcome Dr. Tony Wyss-Coray, a distinguished expert in neurology and brain aging. Dr. Wyss-Coray shares his journey from a childhood fascination with nature to becoming a leading figure in neuroscience and immunology. His initial interest in farming evolved i…
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Do NAD Analogs and Resveratrol Boost Cellular Health and Longevity With Dr. Joe Baur
1:11:19
1:11:19
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1:11:19How can you increase NAD+ levels? And do higher NAD+ levels really lead to better metabolic health? What does the research say on their benefits for longevity? These topics and more are discussed in the latest episode of Longevity by Design with Dr. Joe Baur. Dr. Baur, Professor at the Perelman School of Medicine of the University of Pennsylvania, …
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The Latest Updates in Longevity Research with Dr. Eric Verdin
1:06:04
1:06:04
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1:06:04This episode of Longevity by Design features an interview with Dr. Eric Verdin—the CEO of The Buck Institute. The Buck Institute was the first center dedicated to aging research, and many discoveries within the aging field have come out of this research center. For this episode, Dr. Verdin, Dr. Blander, and Ashely Reaver sat down in person to discu…
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How To Be Smarter About Protein Intake With Dr. Nick Burd
1:03:25
1:03:25
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1:03:25Dr. Nick Burd, PhD, is a skeletal muscle physiologist with an expertise in protein metabolism and exercise. In this episode, Dr. Burd discusses the importance of maintaining muscle mass as we age, expressing that “strong is the new healthy.” While adequate protein intake is an important aspect of gaining muscle and maintaining healthspan, many peop…
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Tracking Your Body’s Data to Improve Health Outcomes with Dr. Sara Gottfried
1:22:55
1:22:55
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1:22:55In this episode of Longevity By Design, Dr. Gil Blander and Ashley Reaver interview Dr. Sara Gottfried. Dr. Gottfried received her MD from Harvard Medical School and completed residency at UCSF, however she is more likely to prescribe a continuous glucose monitor and personalized nutrition plan to her patients than the latest pharmaceutical. This e…
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Ask Me Anything: Lowering Cholesterol and Optimizing VO2max
1:24:46
1:24:46
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1:24:46Did you know that blood cholesterol levels are influenced by far more than just the foods we eat? Are you eager to know how to assess healthspan using your own body's data? This episode of Longevity by Design is an Ask Me Anything between Dr. Gil Blander and Ashley Reaver. We gathered frequently asked questions from the Longevity by Design audience…
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How to Improve Your Healthspan Using DNA Insights with Dr. Bartek Nogal
1:12:39
1:12:39
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1:12:39In this episode of Longevity By Design, Dr. Gil Blander interviews Dr. Bartek Nogal about genetic predispositions to conditions of aging. This episode goes deep into explaining how to improve your healthspan using DNA insights. Dr. Blander and Dr. Nogal talk about bone mineral density, epigenetic age acceleration, cognitive decline, risk of elevate…
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Neurosurgery, Preventing Alzheimer’s Disease, and Optimizing VO2max with Dr. Joseph Maroon
1:16:46
1:16:46
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1:16:46Did you know an estimated 6.7 million Americans aged 65 and older are living with Alzheimer's disease? Alzheimer’s disease is the most common form of dementia, contributing to 60–70% of dementia cases. Being that aging is the primary risk factor for developing dementia, the Longevity By Design team has been eager to discuss dementia on the show. In…
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How GLP-1 Agonists Are Changing Obesity Care with Dr. Spencer Nadolsky
1:13:08
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1:13:08GLP-1 agonist medications have been a popular topic of discussion recently. While this weight loss drug was designed for obesity, GLP-1 agonists like Ozempic have made their way into Hollywood. This has people questioning their safety and possible health risks, especially in the long run. Are GLP-1 agonists a quick fix for weight loss or a lifetime…
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Insulin Resistance, Weight Management, and Eating Optimally with Dr. Mitch Roslin
55:05
55:05
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55:05In this episode of Longevity By Design, Dr. Blander sits down with Dr. Mitch Roslin to discuss insulin resistance. Insulin resistance has been top of mind for Dr. Blander recently, and this conversation offers new insights into how we can prevent insulin resistance through diet and lifestyle. Dr. Roslin parses out the different factors that cause i…
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How Hyperbaric Oxygen Therapy improves cognition with Dr. Shai Efrati
1:03:17
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1:03:17Hyperbaric oxygen therapy (HBOT) is a medical treatment in which patients breathe pure oxygen at higher than normal atmospheric pressure. This increases the amount of oxygen dissolved in body tissues, enabling tissue rejuvenation and accelerated recovery. Historically, HBOT has been used for chronic wounds like diabetic foot ulcers, radiation injur…
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Using Synthetic Biology To Extend Lifespan With Dr. Nan Hao
1:01:23
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1:01:23In 2023, a study was published in the journal Science sharing a breakthrough within the longevity field. This study used synthetic biology to alter the gene networks of yeast cells, and what they found was incredible. They were able to increase the lifespan of yeast cells by 82% compared to control cells. Various media outlets have covered the stud…
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How To Prevent And Reverse Insulin Resistance with Dr. Jennifer Lovejoy
1:20:56
1:20:56
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1:20:56When you hear the word “insulin” what comes to mind first? If your first thought was diabetes, you are not alone. Insulin is most often associated with diabetes, but it plays a key role in many aspects of our health. Did you know that insulin is associated with brain health and cognition? Or that managing insulin levels can aid in weight management…
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Dr. Jennifer Lovejoy—How Hormone Balance and Optimal Metabolism Promote Healthy Aging
1:08:32
1:08:32
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1:08:32What if we told you that sugary foods aren't the only driver of insulin resistance? Many people attribute weight gain solely to a slowed metabolic rate, but the reality is that weight is influenced by dozens of other lifestyle factors. The media often misrepresents the term ‘hormone balance,’ leaving women without adequate advice to address menopau…
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Dr. John Oliffe—Overlooking Men’s Mental Health: A Threat To Longevity
1:03:17
1:03:17
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1:03:17In this episode of Longevity By Design, Dr. Gil Blander welcomes guest Dr. John Oliffe, a renowned expert on men’s mental health. Dr. Blander and Dr. Oliffe discuss the intricacies and challenges regarding mental health faced by men in today’s world, and how when left unaddressed, can threaten men’s longevity. They delve into the complexities of mo…
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Dr. Emma Teeling—DNA Repair Mechanisms and Aging: Lessons From Bats
1:08:18
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1:08:18In this episode of Longevity By Design, Dr. Gil Blander interviews Dr. Emma Teeling, a leading bat researcher from the University of Dublin. They delve into the extraordinary world of bats, discussing how these mammals hold the key to understanding disease resistance, immunity, and longevity. Dr. Teeling explains the unique immune system of bats an…
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Dr. Renee Deehan—Why Everyone Should Care About Women’s Health
1:29:30
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1:29:30In this episode of Longevity by Design, Dr. Renee Deehan discusses pertinent topics of women's health—and why women's health should matter to all. Hormone levels shift throughout a woman's lifespan, and the symptoms and risks associated with suboptimal hormone levels have an economic burden worth addressing. Tune in to learn how Dr. Deehan integrat…
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Dr. Leroy Hood + Dr. Nathan Price—How Assessing Biological Age Improves Wellness
1:24:37
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1:24:37In this episode of Longevity By Design, Dr. Leroy Hood and Dr. Nathan Price discuss their approach to scientific wellness—distilling data into a simple, actionable measurement: biological age. Their goal is to leverage technology to compile data from the brain, body, gut microbiome, and more to create a model for scientific wellness. Dr. Leroy Hood…
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