Radical openmindedness to new ideas.
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Igans Podcasts
Experts discuss relevant and actionable strategies for practice improvement as well as timely clinical topics.
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Surviving the matrix with Max Igan. Visit at http://thecrowhouse.com/home.html Podcast by: https://www.youtube.com/channel/UC3BHgelVBQOuvaLlzH7683A?view_as=subscriber
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Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.
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KDIGO Conversations in Nephrology features global experts covering a wide range of topics for clinicians treating patients with kidney disease.
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Welcome to the new Rare Kidney Disease Show part of the RKD Scientific Network sponsored by Travere Therapeutics. The Rare Kidney Disease Show is your primary source for cutting-edge insights, expert perspectives, and pivotal updates in nephrology. Led by our panel of experts, explore the advances in glomerular nephropathies through compelling conversations, challenging case studies, and discussions tackling hot topics. Join us as we strive to provide you with the ultimate resource to suppor ...
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IgA Nephropathy: Current Treatment Landscape, Disease Burden, and 2-Year PROTECT Trial Data Supporting Sparsentan as an Emerging Treatment Option
Travere Therapeutics
Listeners can expect to learn about: • The disease burden and underlying pathophysiology of IgA nephropathy, including the role of endothelin and angiotensin in disease progression • The current IgAN treatment landscape • The response to sparsentan, a dual endothelin angiotensin receptor antagonist, in patients with IgA nephropathy in the phase 3 PROTECT trial
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This is Max Igan's Official LBRY Channel. If you would like to contribute to ensure the continuation of this channel and the crowhouse website, please do so via the link below: In Lak'ech "The illusion of freedom will continue for as long as it's profitable to continue the illusion. At the point where the illusion becomes too expensive to maintain, they will take down the scenery, move the tables and chairs out of the way, then they will pull back the curtains and you will see the brick wall ...
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conversations with the creative forces in Philippine arts
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1
Navigating the Challenges of IgAN Management: Clinical Implications of Emerging B-Cell Therapies
30:32
30:32
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30:32Alarming in immunoglobulin A nephropathy (IgAN): over 40% present late. Explore latest advancements in management of the most common cause of primary glomerulonephritis worldwide. Credit available for this activity expires: 12/23/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/navigating-challenges-igan-mana…
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Episode 29: How I Treat IgAN: Lessons from the Case Files
20:30
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20:30This third episode in KDIGO’s four-part IgAN series explores how to apply KDIGO guidance in real-world IgAN care through two illustrative patient cases. Building on earlier episodes in the series, the discussion highlights dynamic risk assessment, treatment selection, and monitoring strategies, along with practical decisions about RAS inhibitors ve…
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FF 86 Atacicept for IgAN with Jon Barratt
1:15:27
1:15:27
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1:15:27The Filtrate Joel Topf @kidneyboy.bsky.social (COI) Sophia Ambruso @sophia-kidney.bsky.social Swapnil Hiremath @hswapnil.medsky.social and on LinkedIn Special Guests Jonathan Barratt Professor of Renal Medicine, University of Leicester Google Scholar (COI: all the companies) Editing and Show Notes by Nayan Arora @captainchloride.bsky.social The K…
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"It isn't the rebels who create the troubles of the world, it's the troubles who create the rebels." https://thecrowhouse.com YouTube: https://www.youtube.com/channel/UCegOTmclzjfKuQh0SHflqww BitChute https://www.bitchute.com/channel/TheCrowhouse/ TheCrowhouse Official Shorts: * Bitchute: https://www.bitchute.com/channel/j2HNProivSjB/ * Rumble: htt…
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1
Person-Centered Care in EGFR-Mutated Advanced NSCLC: Optimizing Outcomes and Experiences
31:59
31:59
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31:59How well are you managing patients on EGFR inhibitor therapies in your clinical practice? Credit available for this activity expires: 12/18/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/person-centered-care-egfr-mutated-advanced-nsclc-optimizing-2025a1000xxa?ecd=bdc_podcast_libsyn_mscpedu…
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1
Charting the Course in CLL: A Clinician's Compass for BTK Inhibitor Therapy
34:08
34:08
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34:08Learn from the experts about selecting the right BTK inhibitor therapy for patients with chronic lymphocytic leukaemia (CLL) in UK clinical practice. Credit available for this activity expires: 12/16/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/charting-course-cll-clinicians-compass-btk-inhibitor-therapy-…
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Episode 30: Challenges of Implementing Evidence-Based Guidance for IgA Nephropathy
18:15
18:15
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18:15This final episode in KDIGO’s four-part IgAN series focuses on the challenges and opportunities of implementing the updated KDIGO IgAN Guideline in clinical practice. The conversation examines a shifting treatment paradigm that emphasizes earlier intervention and simultaneous, multi-targeted therapy, while addressing persistent barriers to guidelin…
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1
False Flags and Rapid Fire Rules - Here Comes The Big Showdown
1:14:46
1:14:46
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1:14:46"It isn't the rebels who create the troubles of the world, it's the troubles who create the rebels." https://thecrowhouse.com YouTube: https://www.youtube.com/channel/UCegOTmclzjfKuQh0SHflqww BitChute https://www.bitchute.com/channel/TheCrowhouse/ TheCrowhouse Official Shorts: * Bitchute: https://www.bitchute.com/channel/j2HNProivSjB/ * Rumble: htt…
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1
FF 87 Can Fish Oil Knock the Crap out of Dialysis Associated CV Disease?
1:20:20
1:20:20
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1:20:20The Filtrate Joel Topf @kidneyboy.bsky.social (COI) Swapnil Hiremath @hswapnil.medsky.social and on LinkedIn Pedro Teixeira @nephcrit.bsky.social Special Guests Charmaine E Lok, MD Professor of Medicine at the Faculty of Medicine, University of Toronto Editing and Show Notes by Joel Topf The Kidney Connection written and performed by Tim Yau Show…
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How Are ADCs Shaping the Future of Early Breast Cancer Care? Latest Insights and Emerging Strategies
31:48
31:48
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31:48Did you know that, while well established in the metastatic setting, second-generation antibody-drug conjugates are now moving into the early setting? Credit available for this activity expires: 12/10/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/how-are-adcs-shaping-future-early-breast-cancer-care-latest-…
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Pediatric Low-Grade Glioma With BRAF Alterations: Stories, Science, and Strategies
38:04
38:04
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38:04Join the program for an in-depth discussion on low-grade glioma – from burden and diagnosis to therapies. Credit available for this activity expires: 12/10/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/pediatric-low-grade-glioma-braf-alterations-stories-science-2025a1000x3w?ecd=bdc_podcast_libsyn_mscpedu…
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Hot Topics from Berlin 2025: What Experts Say About the Future of Metastatic Breast Cancer Care
30:28
30:28
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30:28Join this program for relevant updates across the advanced and metastatic breast cancer (mBC) spectrum as presented in October 2025. Credit available for this activity expires: 12/8/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/hot-topics-berlin-2025-what-experts-say-about-future-2025a1000x8r?ecd=bdc_podca…
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1
The Smart Grid as Arrived - Will You Comply
1:02:47
1:02:47
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1:02:47"It isn't the rebels who create the troubles of the world, it's the troubles who create the rebels." https://thecrowhouse.com YouTube: https://www.youtube.com/channel/UCegOTmclzjfKuQh0SHflqww BitChute https://www.bitchute.com/channel/TheCrowhouse/ TheCrowhouse Official Shorts: * Bitchute: https://www.bitchute.com/channel/j2HNProivSjB/ * Rumble: htt…
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1
How Are Oral SERDs Changing the Management of Advanced HR-Positive Breast Cancer?
19:55
19:55
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19:55Where do oral selective estrogen receptor degraders (SERDs) fit in the overall landscape of first- and second-line advanced/metastatic breast cancer? Credit available for this activity expires: 12/04/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/how-are-oral-serds-changing-management-advanced-hr-positive-2…
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1
Staying Ahead of the First Event: Evaluating the Evidence for Early LDL-C Lowering
30:36
30:36
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30:36Preventing the first ASCVD is critically important. In this activity, we explore the evidence for early and intensive lipid lowering to significantly reduce patient's cardiovascular (CV) risk. Credit available for this activity expires: 12/05/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/staying-ahead-firs…
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Optimizing Outcomes for Patients With IgAN: Novel B-Cell Targeted Therapies and the Changing Treatment Paradigm
32:18
32:18
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32:18Is your patient's proteinuria low enough? New KDIGO goals: target the immune cause and hit Credit available for this activity expires: 12/2/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003055?ecd=bdc_podcast_libsyn_mscpedu
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1
Advances in the Pharmacologic Management of Obesity: An Expert Digest of the Latest Data
16:01
16:01
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16:01Are you up to date on emerging pharmacologic therapies transforming obesity and type 2 diabetes care? Credit available for this activity expires: 11/28/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/advances-pharmacologic-management-obesity-expert-digest-2025a1000v94…
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1
Digital ID - The Holy Grail of Human Slavery Systems
1:01:04
1:01:04
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1:01:04"It isn't the rebels who create the troubles of the world, it's the troubles who create the rebels." https://thecrowhouse.com YouTube: https://www.youtube.com/channel/UCegOTmclzjfKuQh0SHflqww BitChute https://www.bitchute.com/channel/TheCrowhouse/ TheCrowhouse Official Shorts: * Bitchute: https://www.bitchute.com/channel/j2HNProivSjB/ * Rumble: htt…
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1
Breaking the Silence: Tackling Liver Fibrosis in MASH: Who to Treat With Novel Therapies
18:45
18:45
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18:45Do you know whom to treat and why? Learn about identifying and treating at-risk metabolic dysfunction-associated steatohepatitis (MASH). Credit available for this activity expires: 11/25/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/breaking-silence-tackling-liver-fibrosis-mash-who-treat-2025a1000waj?ecd…
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1
Coexisting Comorbidities: Advancing Holistic Care in COPD
33:50
33:50
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33:50Are you looking beyond the lung to provide holistic care for your patients with multimorbid chronic obstructive pulmonary disease (COPD)? Credit available for this activity expires: 11/26/2025 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/coexisting-comorbidities-advancing-holistic-care-copd-2025a1000uiz?ecd=…
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1
Novel Biological Approaches for Enhanced Obesity and Diabetes Management – What's Next?
39:10
39:10
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39:10Hear from our panel of obesity and diabetes experts about emerging obesity and type 2 diabetes therapies addressing cardiovascular, hepatic, and metabolic complications. Credit available for this activity expires: 11/25/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003022?ecd=bdc_podcast_libsyn_mscpedu…
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1
Latest Advances in mHSPC: An Update From Berlin 2025
20:06
20:06
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20:06Does the year 2025 mark a true, tangible shift toward biomarker-driven precision medicine for metastatic hormone-sensitive prostate cancer (mHSPC)? Credit available for this activity expires: 11/18/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/latest-advances-mhspc-update-berlin-2025-2025a1000vlk?ecd=bdc_p…
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1
Conference Insights: Breaking Developments in ALK-Positive NSCLC and ES-SCLC
35:03
35:03
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35:03Are you staying up to date on the latest practice-changing data revolutionizing the treatment for lung cancer? Credit available for this activity expires: 11/18/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/conference-insights-breaking-developments-alk-positive-nsclc-2025a1000vwn?ecd=bdc_podcast_libsyn_msc…
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Charting the Course for Metastatic Breast Cancer Care: Optimizing First-Line Treatment and Beyond
1:17:23
1:17:23
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1:17:23ADCs as first-line treatment? ESR1 monitoring before progression? Local therapy for CNS disease? Experts tackle today's toughest decisions. Credit available for this activity expires: 11/14/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/charting-course-metastatic-breast-cancer-care-optimizing-2025a1000v4s…
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Paving the Way for Success in Integrating Biosimilars Into Multiple Sclerosis Care: Optimizing Communication
37:33
37:33
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37:33Do you know what words patients do not want to hear? Credit available for this activity expires: 11/13/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/paving-way-success-integrating-biosimilars-multiple-2025a1000v8w?ecd=bdc_podcast_libsyn_mscpedu
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The Filtrate Joel Topf @kidneyboy.bsky.social Sophia Ambruso @sophia-kidney.bsky.social Nayan Arora @captainchloride.bsky.social Special Guests Brian Rifkin @brianrifkin.bsky.social Anna Gaddy @AnnaGaddy Editing and Show Notes by Joel Topf The Kidney Connection written and performed by Tim Yau Show Notes Brian Rifkin and Cristina Popa ascend to c…
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1
Advancing Personalized Care for Prostate Cancer: Patient-Centered Solutions for mHSPC and nmCRPC
1:19:22
1:19:22
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1:19:22What do patients really think about prostate cancer care? Is it true that 50% of men are still being undertreated? Credit available for this activity expires: 11/12/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/advancing-personalized-care-prostate-cancer-patient-centered-2025a1000uyb?ecd=bdc_podcast_libs…
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1
Reshaping Obesity and Diabetes Care With Innovative Multiagonism Concepts
26:39
26:39
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26:39Hear about the promise of combination therapies and dual and triple agonists in helping people with obesity lose weight and improve overall health. Credit available for this activity expires: 11/11/26Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003041?ecd=bdc_podcast_libsyn_mscpedu…
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The Hidden Battle: Understanding Chronic Inflammation in Aging People Living With HIV and Comorbidities
35:11
35:11
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35:11Untangle the hidden links between chronic inflammation, aging, HIV, and comorbidities. Credit available for this activity expires: 11/5/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003078?ecd=bdc_podcast_libsyn_mscpedu
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Emerging Therapies for MASH: From Theory to Clinical Practice
35:49
35:49
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35:49How much do you know about new therapies for treating fibrosis in MASH and the patients who can benefit most from them? Credit available for this activity expires: 10/29/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003068?ecd=bdc_podcast_libsyn_mscpedu
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FF 84 ACHIEVE: Spironolactone flops in dialysis
1:29:05
1:29:05
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1:29:05The Filtrate Joel Topf @kidneyboy.bsky.social Swapnil [email protected] AC @medpeedskidneys.bsky.social Special Guest Mike Walsh Associate Professor in the Departments of Medicine and Health Research Methods, Evidence, and Impact, McMaster University as well as a Scientist at the Population Health Research Institute and a nephrologi…
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1
Interpreting JC Virus Test Results in Multiple Sclerosis Management: Are You Up to Speed?
39:57
39:57
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39:57What do expert recommendations say about John Cunningham (JC) virus testing when switching to a biosimilar? Credit available for this activity expires: 10/31/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/interpreting-jc-virus-test-results-multiple-sclerosis-2025a1000qzm?ecd=bdc_podcast_libsyn_mscpedu…
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Targeting Diabesity From Multiple Angles: Future Prospects and Imminent Realities
15:59
15:59
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15:59Diabesity at the annual European diabetes meeting: What did you miss? Credit available for this activity expires: 10/30/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003003?ecd=bdc_podcast_libsyn_mscpedu
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Episode 28: APOL1 Screening and Early Detection - Patient and Clinician Perspectives
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13:30In the final episode of KDIGO’s three-part Conversations in Nephrology series on APOL1 kidney disease, host Kirk Campbell, MD (University of Pennsylvania, United States), speaks with Titilayo Ilori, MD (Boston University, United States), and kidney health advocate Joshua Albright (United States) about how APOL1 genetic testing can shape the future …
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Episode 27: Management of Patients with APOL1 Kidney Disease
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19:15In this second installment of KDIGO’s three-part podcast series on APOL1 kidney disease, host Kirk Campbell, MD (University of Pennsylvania, United States), welcomes Barry Freedman, MD (Wake Forest University School of Medicine, United States) for a practical discussion on patient management. They examine how APOL1 risk variants influence progressi…
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Episode 26: Burden and Pathophysiology of APOL1 Kidney Disease
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13:00This is the first episode of a three-part KDIGO Conversations in Nephrology series on APOL1 kidney disease. Host Kirk Campbell, MD (University of Pennsylvania, United States), speaks with Bessie Young, MD (University of Washington, United States) about the discovery, burden, and biology of APOL1 kidney disease. Their discussion explores how APOL1 v…
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1
Neovascular AMD: Optimizing Disease Control for Your Patients
28:06
28:06
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28:06When and how to use longer durability therapies in neovascular age-related macular degeneration (nAMD). Credit available for this activity expires: 10/27/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1002961?ecd=bdc_podcast_libsyn_mscpedu
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The Hidden Hurdle: Practical Insights on Drug-Drug Interactions in Prostate Cancer Management
43:58
43:58
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43:58Did you know more patients with prostate cancer die from heart disease than cancer? Learn to master drug interactions to protect both outcomes here. Credit available for this activity expires: 10/17/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1003015?ecd=bdc_podcast_libsyn_mscpedu…
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1
FF 83 CONFIDENCE: Can We Start Flozins and Finerenone Simultaneously?
1:29:10
1:29:10
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1:29:10The Filtrate Joel Topf @kidneyboy.bsky.social Swapnil Hiremath @hswapnil.medsky.social Nayan Arora captainchloride.bsky.social Sopia Ambruso @sophia-kidney.bsky.social Special Guests Brendon Neuen @brendonneuen.bsky.social Associate Professor and Program Lead, Renal and Metabolic at The George Institute for Global Health. Nephrologist and Director …
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"It isn't the rebels who create the troubles of the world, it's the troubles who create the rebels." https://thecrowhouse.com YouTube: https://www.youtube.com/channel/UCegOTmclzjfKuQh0SHflqww BitChute https://www.bitchute.com/channel/TheCrowhouse/ TheCrowhouse Official Shorts: * Bitchute: https://www.bitchute.com/channel/j2HNProivSjB/ * Rumble: htt…
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1
Practical Idealism In Action - The Kalergi Plan
16:26
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16:26The "immigrant invasion" of the west, and the race mixing that will ensue is absolutely deliberate and essential for the fulfillment of the jewish 'Kalergi Plan' to genocide all white people of European descent, as outlined in the 1925 book: 'Practical Idealism" by Richard Coudenhove Kalergi. "It isn't the rebels who create the troubles of the worl…
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1
If There Was Ever A Hill To Die On This Is It
2:17:43
2:17:43
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2:17:43"It isn't the rebels who create the troubles of the world, it's the troubles who create the rebels." https://thecrowhouse.com YouTube: https://www.youtube.com/channel/UCegOTmclzjfKuQh0SHflqww BitChute https://www.bitchute.com/channel/TheCrowhouse/ TheCrowhouse Official Shorts: * Bitchute: https://www.bitchute.com/channel/j2HNProivSjB/ * Rumble: htt…
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1
Managing Diabetic Macular Edema in Clinical Practice
34:03
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34:03The experts discuss strategies, new-generation anti-vascular endothelial growth factors (VEGFs), and the evidence that supports their use. Credit available for this activity expires: 9/30/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1002951?ecd=bdc_podcast_libsyn_mscpedu…
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1
Episode 25: Treatment Revolution in IgA Nephropathy
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14:30This second episode in KDIGO’s four-part IgAN series addresses the treatment revolution in IgAN. Join Dana Rizk, MD (University of Alabama at Birmingham, US), and Shikha Wadhwani, MD (Indiana University School of Medicine, US), as they discuss how breakthroughs in understanding disease pathophysiology are fueling a wave of new therapies that go bey…
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Episode 24: Overview of the Latest Guidance in IgA Nephropathy Management
19:00
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19:00This is the first episode in KDIGO's four-part series on the KDIGO 2025 IgAN/IgAV Guideline. Join Dana Rizk, MD (University of Alabama at Birmingham, United States), and Brad Rovin, MD (Ohio State University, United States), Co-Chair of the 2025 KDIGO IgAN Guideline, for a deep dive into the latest updates in patient care. Their conversation explor…
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